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Mammalian Phenotype (MP): abnormal ion homeostasis

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ 1:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
0:   abnormal ion homeostasis [MP:0001765] <15>(9|12) (11|4|0)
- 1:   abnormal calcium ion homeostasis [MP:0004231] <4>(2|3) (3|3|0)
- 1:   abnormal erythrocyte ion transport [MP:0012384] <4>(0|0) (0|0|0)
- 1:   abnormal sodium ion homeostasis [MP:0011977] <3>(4|4) (5|0|0)
- 1:   abnormal chloride level [MP:0012007] <2>(1|1) (1|0|0)
- 1:   abnormal circulating phosphate level [MP:0001565] <2>(0|0) (0|0|0)
- 1:   abnormal nitrate level [MP:0020104] <2>(0|0) (0|0|0)
- 1:   abnormal nitrite level [MP:0020107] <2>(0|0) (0|0|0)
- 1:   abnormal plasma anion gap [MP:0005624] <2>(0|0) (0|0|0)
- 1:   abnormal potassium ion homeostasis [MP:0011978] <2>(0|0) (0|0|0)
- 1:   abnormal copper homeostasis [MP:0003951] <1>(1|1) (1|0|0)
- 1:   abnormal iron homeostasis [MP:0005637] <1>(0|0) (0|0|0)
- 1:   abnormal magnesium ion homeostasis [MP:0011979] <1>(0|0) (0|0|0)
- 1:   abnormal renal phosphate reabsorbtion [MP:0010110](0|0) (0|0|0)
- 1:   abnormal urine organic anion level [MP:0006272](0|0) (0|0|0)
- 1:   abnormal urine organic cation level [MP:0006273](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Ammonium transporter0Direct
HMA, heavy metal-associated domain0Direct
PLC-like phosphodiesterases0.01138Inherited
LDL receptor-like module0.03009Inherited
Flavoproteins0.03198Inherited
Riboflavin synthase domain-like0.04532Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.04532Inherited
Transducin (alpha subunit), insertion domain0.1387Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Ammonium transporter0Direct
HMA, heavy metal-associated domain0Direct
Meta-cation ATPase, catalytic domain P0.0000887Direct
ABC transporter transmembrane region0.000301Direct
Cytochrome p450 reductase N-terminal domain-like0.003166Inherited
Mammalian PLC0.004023Inherited
NADPH-cytochrome p450 reductase-like0.01027Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.01027Inherited
LDL receptor-like module0.01945Inherited
PLC-like (P variant)0.04329Inherited
Transducin (alpha subunit), insertion domain0.107Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
HMA, heavy metal-associated domain0Direct
Ammonium transporter0Direct
PLC-like phosphodiesterases0.007185Inherited
LDL receptor-like module0.02047Inherited
Flavoproteins0.02186Inherited
Riboflavin synthase domain-like0.03179Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.03179Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.04308Inherited
Transducin (alpha subunit), insertion domain0.1088Inherited
Family A G protein-coupled receptor-like0.5163Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
81324,81324
  • 81324 - Voltage-gated potassium channels
  • 81324 - Voltage-gated potassium channels
  • 0.0005066Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01666Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.01666Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.08158Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)