Mammalian Phenotype (MP): abnormal muscle morphology

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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)

+ + 2: mammalian phenotype [MP:0000001] <29>

+ 1: muscle phenotype [MP:0005369] <2> (49|57) (54|37|28)

0: abnormal muscle morphology [MP:0002108] <16> (28|31) (31|22|21)

- 1: abnormal skeletal muscle morphology [MP:0000759] <25> (15|15) (16|9|5)

- 1: abnormal smooth muscle morphology [MP:0000767] <13> (6|6) (6|1|0)

- 1: abnormal muscle development [MP:0000733] <7> (1|2) (1|0|0)

- 1: abnormal muscle fiber morphology [MP:0004087] <7> (4|6) (5|7|6)

- 1: abnormal cardiac muscle tissue morphology [MP:0010630] <5> (2|3) (2|0|3)

- 1: abnormal eye muscle morphology [MP:0003686] <4> (1|1) (1|0|0)

- 1: increased muscle tumor incidence [MP:0010290] <4> (0|0) (0|0|0)

- 1: muscular atrophy [MP:0002269] <4> (0|0) (0|0|0)

- 1: abnormal muscle weight [MP:0004233] <3> (3|2) (3|0|0)

- 1: abnormal tendon morphology [MP:0005503] <3> (2|3) (3|0|0)

- 1: abnormal muscle glycogen level [MP:0014068] <2> (1|0) (1|0|0)

- 1: muscle degeneration [MP:0000749] <2> (1|1) (1|0|0)

- 1: decreased muscle tumor incidence [MP:0012413] <1> (0|0) (0|0|0)

- 1: muscle hypoplasia [MP:0000734] <1> (0|0) (0|0|0)

- 1: calcified muscle [MP:0003199] (0|0) (0|0|0)

- 1: dystrophic muscle [MP:0000752] (0|1) (0|2|1)

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Superfamily

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SCOP term	FDR (all)	Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain	0	Direct
Troponin coil-coiled subunits	0	Direct
Lamin A/C globular tail domain	0	Direct
TB module/8-cys domain	0.00004743	Direct
HLH, helix-loop-helix DNA-binding domain	0.0001422	Direct
Growth factor receptor domain	0.001187	Inherited
SRF-like	0.002192	Inherited
Flavoproteins	0.003604	Inherited
Homeodomain-like	0.006681	Inherited
Cystine-knot cytokines	0.01424	Inherited
B-box zinc-binding domain	0.06649	Inherited
BPTI-like	0.07357	Inherited
Kazal-type serine protease inhibitors	0.113	Inherited
Clavaminate synthase-like	0.1482	Inherited
"Winged helix" DNA-binding domain	0.2422	Inherited
Metalloproteases ("zincins"), catalytic domain	0.2495	Inherited
alpha-catenin/vinculin-like	0.3065	Inherited
Thyroglobulin type-1 domain	0.39	Inherited
Notch domain	0.39	Inherited
(Trans)glycosidases	0.3979	Inherited
RING/U-box	0.4471	Inherited
Spermadhesin, CUB domain	0.452	Inherited
Riboflavin synthase domain-like	0.4752	Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain	0.4752	Inherited
TIMP-like	0.4752	Inherited
L domain-like	0.4963	Inherited
Actin-like ATPase domain	0.6713	Inherited
WW domain	0.8734	Inherited

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Family

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SCOP term	FDR (all)	Annotation (direct or inherited)
Lamin A/C globular tail domain	0	Direct
Nitric oxide (NO) synthase oxygenase domain	0	Direct
Troponin T	0	Direct
Cytochrome p450 reductase N-terminal domain-like	0	Direct
L domain	0.000005872	Direct
Growth factor receptor domain	0.00001054	Direct
TB module/8-cys domain	0.00003464	Direct
HLH, helix-loop-helix DNA-binding domain	0.0001881	Direct
NADPH-cytochrome p450 reductase-like	0.0002656	Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like	0.0002656	Direct
Forkhead DNA-binding domain	0.001066	Inherited
Paired domain	0.001353	Inherited
SRF-like	0.001599	Inherited
Homeodomain	0.004297	Inherited
EGF-type module	0.01148	Inherited
Plakin repeat	0.01184	Inherited
ZZ domain	0.03277	Inherited
B-box zinc-binding domain	0.06164	Inherited
Small Kunitz-type inhibitors & BPTI-like toxins	0.0645	Inherited
Transforming growth factor (TGF)-beta	0.07344	Inherited
Ovomucoid domain III-like	0.118	Inherited
Laminin-type module	0.1629	Inherited
28-residue LRR	0.2038	Inherited
I set domains	0.2508	Inherited
EF-hand modules in multidomain proteins	0.3572	Inherited
Notch domain	0.3572	Inherited
Thyroglobulin type-1 domain	0.3572	Inherited
Spermadhesin, CUB domain	0.4222	Inherited
Ngr ectodomain-like	0.6297	Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain	0.6447	Inherited
WW domain	0.857	Inherited

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Supra-domain (including individual superfamily)

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Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain	0	Direct
Troponin coil-coiled subunits	0	Direct
Lamin A/C globular tail domain	0	Direct
TB module/8-cys domain	0.00002229	Direct
HLH, helix-loop-helix DNA-binding domain	0.00007081	Direct
Growth factor receptor domain	0.0006536	Direct
SRF-like	0.00125	Inherited
Flavoproteins	0.002114	Inherited
Homeodomain-like	0.004078	Inherited
Cystine-knot cytokines	0.009129	Inherited
Plakin repeat	0.009526	Inherited
B-box zinc-binding domain	0.04834	Inherited
BPTI-like	0.05403	Inherited
Kazal-type serine protease inhibitors	0.08665	Inherited
Clavaminate synthase-like	0.1171	Inherited
EGF/Laminin	0.1986	Inherited
"Winged helix" DNA-binding domain	0.2025	Inherited
Metalloproteases ("zincins"), catalytic domain	0.2092	Inherited
alpha-catenin/vinculin-like	0.2629	Inherited
Thyroglobulin type-1 domain	0.3436	Inherited
Notch domain	0.3436	Inherited
(Trans)glycosidases	0.3513	Inherited
RING/U-box	0.3996	Inherited
Spermadhesin, CUB domain	0.4044	Inherited
TIMP-like	0.4275	Inherited
Riboflavin synthase domain-like	0.4275	Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain	0.4275	Inherited
L domain-like	0.4487	Inherited
Intermediate filament protein, coiled coil region	0.6291	Inherited
Actin-like ATPase domain	0.6291	Inherited
WW domain	0.8443	Inherited

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Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
54236,57889 54236 - Ubiquitin-like 57889 - Cysteine-rich domain	0	Direct
55486,49854 55486 - Metalloproteases ("zincins"), catalytic domain 49854 - Spermadhesin, CUB domain	0	Direct
49265,56112 49265 - Fibronectin type III 56112 - Protein kinase-like (PK-like)	0	Direct
64593,74853 64593 - Intermediate filament protein, coiled coil region 74853 - Lamin A/C globular tail domain	0	Direct
52058,57184 52058 - L domain-like 57184 - Growth factor receptor domain	0.000003542	Direct
57184,52058 57184 - Growth factor receptor domain 52058 - L domain-like	0.000003542	Direct
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0.0002744	Direct
57581,57196 57581 - TB module/8-cys domain 57196 - EGF/Laminin	0.0008158	Direct
57196,57581 57196 - EGF/Laminin 57581 - TB module/8-cys domain	0.0008158	Direct
57196,90193 57196 - EGF/Laminin 90193 - Notch domain	0.00125	Inherited
57850,57845 57850 - RING/U-box 57845 - B-box zinc-binding domain	0.00238	Inherited
75399,75399 75399 - Plakin repeat 75399 - Plakin repeat	0.004294	Inherited
47473,57850 47473 - EF-hand 57850 - RING/U-box	0.004294	Inherited
100895,100895 100895 - Kazal-type serine protease inhibitors 100895 - Kazal-type serine protease inhibitors	0.009526	Inherited
47473,47473 47473 - EF-hand 47473 - EF-hand	0.1537	Inherited
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III	0.2416	Inherited
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like	0.2629	Inherited
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin	0.2629	Inherited
57184,57610 57184 - Growth factor receptor domain 57610 - Thyroglobulin type-1 domain	0.3436	Inherited
48726,56112 48726 - Immunoglobulin 56112 - Protein kinase-like (PK-like)	0.3436	Inherited
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin	0.3436	Inherited
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin	0.3508	Inherited

(show details)

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
57196,49854,57196 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin	0	Direct
57184,52058,57184 57184 - Growth factor receptor domain 52058 - L domain-like 57184 - Growth factor receptor domain	0	Direct
49854,49854,57196 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin	0	Direct
55486,49854,49854 55486 - Metalloproteases ("zincins"), catalytic domain 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain	0	Direct
48726,49265,56112 48726 - Immunoglobulin 49265 - Fibronectin type III 56112 - Protein kinase-like (PK-like)	0	Direct
52058,57184,52058 52058 - L domain-like 57184 - Growth factor receptor domain 52058 - L domain-like	0.000003542	Direct
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0.00001756	Direct
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin	0.0001933	Direct
57581,57196,57196 57581 - TB module/8-cys domain 57196 - EGF/Laminin 57196 - EGF/Laminin	0.0001943	Direct
57196,57196,57581 57196 - EGF/Laminin 57196 - EGF/Laminin 57581 - TB module/8-cys domain	0.0001943	Direct
90257,90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments 90257 - Myosin rod fragments	0.0001943	Direct
57184,57196,57184 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0.0008158	Direct
57196,57184,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0.0008158	Direct
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin	0.00125	Inherited
47473,47473,57850 47473 - EF-hand 47473 - EF-hand 57850 - RING/U-box	0.004294	Inherited
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III	0.08917	Inherited
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain)	0.1171	Inherited
47220,47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like	0.2629	Inherited
48726,49265,49265 48726 - Immunoglobulin 49265 - Fibronectin type III 49265 - Fibronectin type III	0.3436	Inherited
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat	0.4275	Inherited
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin	0.477	Inherited

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Mammalian Phenotype (MP): abnormal muscle morphology

Superfamily

Family

Supra-domain (including individual superfamily)