SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal alpha-beta T cell number

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + + 9:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + 7:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + + 7:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + 6:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(58|86) (66|47|21)
+ + + + + + 6:   abnormal immune system morphology [MP:0000685] <3>(51|76) (60|35|18)
+ + + + + 5:   abnormal hematopoietic cell morphology [MP:0013656] <9>(49|77) (60|43|18)
+ + + + + 5:   abnormal immune system cell morphology [MP:0000716] <5>(38|63) (48|29|16)
+ + + + 4:   abnormal mononuclear cell morphology [MP:0008247] <2>(34|57) (41|28|14)
+ + + + 4:   abnormal leukocyte morphology [MP:0008246] <4>(37|62) (47|29|15)
+ + + + 4:   abnormal hematopoietic cell number [MP:0011180] <7>(34|57) (43|29|13)
+ + + 3:   abnormal lymphocyte morphology [MP:0002619] <5>(28|46) (33|26|14)
+ + + 3:   abnormal leukocyte cell number [MP:0000217] <8>(29|49) (37|25|12)
+ + 2:   abnormal T cell morphology [MP:0008037] <9>(14|25) (18|19|11)
+ + 2:   abnormal lymphocyte cell number [MP:0000717] <6>(18|38) (25|21|9)
+ 1:   abnormal alpha-beta T cell morphology [MP:0012762] <13>(7|17) (8|14|6)
+ 1:   abnormal T cell number [MP:0006387] <11>(8|22) (16|15|7)
0:   abnormal alpha-beta T cell number [MP:0012763] <5>(3|11) (4|8|2)
- 1:   abnormal CD4-positive, alpha beta T cell number [MP:0008073] <9>(1|8) (2|7|2)
- 1:   abnormal CD8-positive, alpha-beta T cell number [MP:0008077] <6>(2|7) (2|5|2)
- 1:   abnormal NK T cell number [MP:0008038] <5>(0|0) (0|0|0)
- 1:   decreased alpha-beta T cell number [MP:0012765] <3>(3|6) (3|3|1)
- 1:   increased alpha-beta T cell number [MP:0012764] <2>(0|1) (1|1|1)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.2207Inherited
MHC antigen-recognition domain0.3652Inherited
Integrin domains0.4425Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.0003584Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.06497Inherited
Interleukin 17F, IL-17F0.1841Inherited
V set domains (antibody variable domain-like)0.2742Inherited
MHC antigen-recognition domain0.3207Inherited
C1 set domains (antibody constant domain-like)0.327Inherited
Integrin domains0.3962Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.4841Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.6415Inherited
TNF receptor-like0.7315Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.1824Inherited
MHC antigen-recognition domain0.3194Inherited
Integrin domains0.395Inherited
TNF receptor-like0.7307Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.0003088Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.001242Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.002189Inherited
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.006901Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.1824Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.2562Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.3194Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.4821Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0003088Direct
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.006901Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)