SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal interventricular septum morphology

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   cardiovascular system phenotype [MP:0005385] <2>(67|85) (77|57|35)
+ + + 3:   abnormal cardiovascular system morphology [MP:0002127] <7>(48|65) (53|44|33)
+ + 2:   abnormal heart morphology [MP:0000266] <22>(27|44) (28|25|19)
+ 1:   abnormal heart septum morphology [MP:0006113] <4>(5|15) (7|9|3)
+ 1:   abnormal heart ventricle morphology [MP:0005294] <14>(11|22) (13|12|6)
0:   abnormal interventricular septum morphology [MP:0000281] <5>(4|10) (5|6|2)
- 1:   ventricular septal defect [MP:0010402] <4>(3|6) (4|3|0)
- 1:   abnormal interventricular septum membranous part morphology [MP:0008823] <3>(1|1) (1|1|0)
- 1:   abnormal interventricular septum thickness [MP:0020136] <2>(0|2) (0|2|1)
- 1:   abnormal interventricular septum muscular part morphology [MP:0010498] <1>(0|0) (0|0|0)
- 1:   common ventricle [MP:0010432](1|1) (1|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Blood coagulation inhibitor (disintegrin)0.00107Inherited
Orange domain-like0.001263Inherited
SMAD MH1 domain0.002117Inherited
HLH, helix-loop-helix DNA-binding domain0.1499Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Cyclin0.0006735Direct
Blood coagulation inhibitor (disintegrin)0.0006735Direct
Hairy Orange domain0.0007812Direct
SMAD MH1 domain0.001358Inherited
SMAD domain0.001358Inherited
Erythroid transcription factor GATA-10.001358Inherited
HLH, helix-loop-helix DNA-binding domain0.1042Inherited
Forkhead DNA-binding domain0.1302Inherited
Growth factor receptor domain0.1972Inherited
L domain0.2515Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Blood coagulation inhibitor (disintegrin)0.0005865Direct
Orange domain-like0.0007001Direct
SMAD MH1 domain0.001207Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.1163Inherited
HLH, helix-loop-helix DNA-binding domain0.1186Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.000228Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.0005865Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.0007001Direct
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.001136Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.267Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.267Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.00002737Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.267Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)