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Mammalian Phenotype (MP): seizures

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   behavior/neurological phenotype [MP:0005386] <1>(38|61) (42|40|24)
+ + 2:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ 1:   abnormal nervous system physiology [MP:0003633] <38>(43|60) (52|31|18)
+ 1:   abnormal behavior [MP:0004924] <19>(37|56) (41|37|22)
0:   seizures [MP:0002064] <6>(10|15) (13|3|0)
- 1:   abnormal seizure response to inducing agent [MP:0009357] <5>(5|10) (7|1|0)
- 1:   convulsive seizures [MP:0000947] <5>(3|4) (3|2|0)
- 1:   nonconvulsive seizures [MP:0000948] <1>(4|3) (5|1|0)
- 1:   febrile seizures [MP:0012011](0|0) (0|0|0)
- 1:   focal seizures [MP:0014120](0|0) (0|0|0)
- 1:   sporadic seizures [MP:0000951](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Metallothionein0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Voltage-gated potassium channels0.0000003331Direct
Periplasmic binding protein-like II0.0007641Direct
Periplasmic binding protein-like I0.0007652Direct
Neurotransmitter-gated ion-channel transmembrane pore0.001583Inherited
Nicotinic receptor ligand binding domain-like0.001583Inherited
Flavoproteins0.006725Inherited
PreATP-grasp domain0.006833Inherited
Glutathione synthetase ATP-binding domain-like0.05356Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Synapsin C-terminal domain0Direct
Metallothionein0Direct
Synapsin domain0Direct
Voltage-gated potassium channels0.0001085Direct
Phosphate binding protein-like0.0004606Direct
Nicotinic receptor ligand binding domain-like0.0009993Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0009993Direct
NADPH-cytochrome p450 reductase-like0.001303Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.001303Inherited
Cytochrome p450 reductase N-terminal domain-like0.001303Inherited
Tetramerization domain of potassium channels0.002427Inherited
Leucine zipper domain0.003084Inherited
Cytoplasmic domain of inward rectifier potassium channel0.007846Inherited
Rhodopsin-like0.4725Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Metallothionein0Direct
Voltage-gated potassium channels0.000000134Direct
Periplasmic binding protein-like II0.0004112Direct
Periplasmic binding protein-like I0.0004119Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0008886Direct
Nicotinic receptor ligand binding domain-like0.0008886Direct
Leucine zipper domain0.002782Inherited
Flavoproteins0.004106Inherited
PreATP-grasp domain0.004179Inherited
Riboflavin synthase domain-like0.02612Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.02612Inherited
Glutathione synthetase ATP-binding domain-like0.03803Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0008886Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.004106Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.007245Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)