Mammalian Phenotype (MP): abnormal aortic valve morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children)	MP term [MP ID] <#Children>	(#SF|#FA)	#Supra-domain (Single|Duplex|Triple)
+ + + + + + 6:	mammalian phenotype [MP:0000001] <29>
+ + + + + 5:	cardiovascular system phenotype [MP:0005385] <2>	(67|85)	(77|57|35)
+ + + + 4:	abnormal cardiovascular system morphology [MP:0002127] <7>	(48|65)	(53|44|33)
+ + + 3:	abnormal heart ventricle morphology [MP:0005294] <14>	(11|22)	(13|12|6)
+ + + 3:	abnormal heart morphology [MP:0000266] <22>	(27|44)	(28|25|19)
+ + 2:	abnormal heart valve morphology [MP:0000285] <9>	(4|5)	(4|3|0)
+ + 2:	abnormal heart left ventricle morphology [MP:0003921] <5>	(4|3)	(4|3|2)
+ + 2:	abnormal heart ventricle outflow tract morphology [MP:0010224] <2>	(2|3)	(2|3|0)
+ 1:	abnormal heart left ventricle outflow tract morphology [MP:0010429] <2>	(1|2)	(1|2|0)
+ 1:	abnormal semilunar valve morphology [MP:0002746] <2>	(2|3)	(2|3|0)
0:	abnormal aortic valve morphology [MP:0002747] <9>	(1|2)	(1|2|0)
- 1:	abnormal aortic valve cusp morphology [MP:0010595] <4>	(0|0)	(0|0|0)
- 1:	thick aortic valve [MP:0010594] <1>	(0|0)	(0|0|0)
- 1:	abnormal aortic valve anulus morphology [MP:0010598]	(0|0)	(0|0|0)
- 1:	aortic valve atresia [MP:0006115]	(0|0)	(0|0|0)
- 1:	aortic valve prolapse [MP:0006118]	(0|0)	(0|0|0)
- 1:	aortic valve stenosis [MP:0006117]	(0|0)	(0|0|0)
- 1:	calcified aortic valve [MP:0006116]	(0|0)	(0|0|0)
- 1:	enlarged aortic valve [MP:0010591]	(0|0)	(0|0|0)
- 1:	patent aortic valve [MP:0010610]	(0|0)	(0|0|0)

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Superfamily

Superfamily domains annotated to this MP term (Not in SDMP)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
Blood coagulation inhibitor (disintegrin)	0.0000003598	DIRECT

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Family

Family domains annotated to this MP term (Not in SDMP)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
Blood coagulation inhibitor (disintegrin)	0.0000003191	DIRECT
Reprolysin-like	0.00009788	DIRECT

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Supra-domain (including individual superfamily)

Supra-domains annotated to this MP term (Not in SPMP)
Highlighted in gray are those with FDR>0.001

Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
Blood coagulation inhibitor (disintegrin)	0.0000001451	DIRECT

Supra-domains annotated to this MP term (Not in SPMP)
Highlighted in gray are those with FDR>0.001

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
55486,57552 55486 - Metalloproteases ("zincins"), catalytic domain 57552 - Blood coagulation inhibitor (disintegrin)	0.0000001451	DIRECT
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain	0.0009816	DIRECT