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Mammalian Phenotype (MP): abnormal leukocyte migration

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + 4:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   abnormal hematopoietic system physiology [MP:0001545] <5>(39|53) (40|38|21)
+ + + 3:   cellular phenotype [MP:0005384] <6>(95|116) (103|56|31)
+ + + 3:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + 2:   abnormal cell-mediated immunity [MP:0002421] <3>(35|48) (37|33|21)
+ + 2:   abnormal immune cell physiology [MP:0001819] <3>(35|48) (37|33|21)
+ + 2:   abnormal blood cell physiology [MP:0012382] <3>(38|53) (39|38|21)
+ + 2:   abnormal cell physiology [MP:0005621] <24>(77|96) (84|46|25)
+ + 2:   abnormal adaptive immunity [MP:0002420] <8>(36|48) (38|33|21)
+ 1:   abnormal leukocyte physiology [MP:0002442] <5>(34|48) (36|33|20)
+ 1:   abnormal cell migration [MP:0003091] <14>(13|16) (14|12|6)
0:   abnormal leukocyte migration [MP:0003156] <7>(8|9) (8|5|3)
- 1:   abnormal macrophage chemotaxis [MP:0010760] <2>(1|0) (1|0|0)
- 1:   abnormal cellular extravasation [MP:0009858] <1>(3|4) (4|3|2)
- 1:   abnormal dendritic cell migration [MP:0020349] <1>(0|0) (0|0|0)
- 1:   abnormal leukocyte adhesion [MP:0003628] <1>(2|3) (2|1|0)
- 1:   enhanced leukocyte migration [MP:0020213](0|0) (0|0|0)
- 1:   impaired leukocyte migration [MP:0020212](0|0) (0|0|0)
- 1:   increased lymphocyte chemotaxis [MP:0011826](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin beta tail domain0.000003118Direct
Integrin domains0.00002314Direct
vWA-like0.0002823Direct
Family A G protein-coupled receptor-like0.0003278Direct
EGF/Laminin0.0006656Direct
Complement control module/SCR domain0.006048Inherited
Integrin alpha N-terminal domain0.015Inherited
C-type lectin-like0.05345Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin beta tail domain0.00000208Direct
Integrin beta EGF-like domains0.000004995Direct
Integrin A (or I) domain0.000009203Direct
Integrin domains0.00001481Direct
Rhodopsin-like0.00006522Direct
Complement control module/SCR domain0.004879Inherited
Integrin alpha N-terminal domain0.007054Inherited
EGF-type module0.02499Inherited
C-type lectin domain0.1652Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Integrin beta tail domain0.000001319Direct
Integrin domains0.00001049Direct
vWA-like0.0001449Direct
Family A G protein-coupled receptor-like0.0001698Direct
EGF/Laminin0.000356Direct
Complement control module/SCR domain0.003657Inherited
Integrin alpha N-terminal domain0.009622Inherited
C-type lectin-like0.03795Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.000001319Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.000001319Direct
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.006014Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.006014Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.007963Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.000001319Direct
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.006014Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.02269Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)