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Mammalian Phenotype (MP): abnormal nephron morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   renal/urinary system phenotype [MP:0005367] <2>(41|47) (46|26|11)
+ + 2:   abnormal renal/urinary system morphology [MP:0000516] <14>(31|36) (36|22|11)
+ 1:   abnormal kidney morphology [MP:0002135] <29>(26|28) (28|15|6)
0:   abnormal nephron morphology [MP:0003881] <8>(19|22) (21|12|3)
- 1:   abnormal renal tubule morphology [MP:0002703] <11>(8|9) (9|4|0)
- 1:   abnormal renal corpuscle morphology [MP:0002827] <6>(10|15) (12|9|3)
- 1:   abnormal nephron morphogenesis [MP:0012024] <2>(0|0) (0|0|0)
- 1:   abnormal nephron number [MP:0011289] <1>(2|1) (2|0|0)
- 1:   absent nephron [MP:0011292](0|0) (0|0|0)
- 1:   dilated nephron [MP:0011293](0|0) (0|0|0)
- 1:   nephron necrosis [MP:0011291](0|0) (0|0|0)
- 1:   renal cast [MP:0011402](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Families 57/38 glycoside transferase middle domain0.00002047Direct
Glycoside hydrolase/deacetylase0.00009308Direct
Galactose mutarotase-like0.0002543Direct
HCP-like0.003732Inherited
L30e-like0.006112Inherited
Bcl-2 inhibitors of programmed cell death0.009216Inherited
Nuclear receptor ligand-binding domain0.06245Inherited
Sema domain0.08992Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.1233Inherited
TNF receptor-like0.1283Inherited
Plexin repeat0.165Inherited
(Trans)glycosidases0.2311Inherited
C-type lectin-like0.2341Inherited
Riboflavin synthase domain-like0.2572Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.2572Inherited
Flavoproteins0.2572Inherited
Integrin domains0.4826Inherited
Cystine-knot cytokines0.5614Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
alpha-mannosidase0.00001351Direct
alpha-mannosidase, domain 20.00001351Direct
alpha-mannosidase, C-terminal domain0.0001641Direct
Bcl-2 inhibitors of programmed cell death0.007178Inherited
Short-chain cytokines0.0235Inherited
Nuclear receptor ligand-binding domain0.05465Inherited
Nuclear receptor0.05465Inherited
Sema domain0.0796Inherited
Leucine zipper domain0.144Inherited
Plexin repeat0.1542Inherited
TNF receptor-like0.1661Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.1661Inherited
NADPH-cytochrome p450 reductase-like0.2379Inherited
Noncollagenous (NC1) domain of collagen IV0.2379Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.2379Inherited
Cytochrome p450 reductase N-terminal domain-like0.2379Inherited
Laminin-type module0.361Inherited
VWC domain0.361Inherited
Transforming growth factor (TGF)-beta0.4262Inherited
Integrin domains0.4681Inherited
Tetratricopeptide repeat (TPR)0.5456Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Families 57/38 glycoside transferase middle domain0.000009188Direct
Glycoside hydrolase/deacetylase0.00004472Direct
Galactose mutarotase-like0.0001298Direct
HCP-like0.00219Inherited
L30e-like0.003703Inherited
Bcl-2 inhibitors of programmed cell death0.00572Inherited
Nuclear receptor ligand-binding domain0.04514Inherited
Sema domain0.06711Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.09532Inherited
TNF receptor-like0.09968Inherited
Leucine zipper domain0.1193Inherited
Plexin repeat0.1319Inherited
(Trans)glycosidases0.1922Inherited
C-type lectin-like0.1949Inherited
Riboflavin synthase domain-like0.2164Inherited
Flavoproteins0.2164Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.2164Inherited
EGF/Laminin0.4078Inherited
Integrin domains0.4349Inherited
Cystine-knot cytokines0.5149Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0.000009188Direct
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.0001245Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0001298Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.001135Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.01495Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.06435Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.06711Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.06711Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.2164Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.2442Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.6225Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.6612Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.00004472Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.05622Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.7928Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)