SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Mammalian Phenotype (MP): decreased circulating insulin-like growth factor I level

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ + + + 4:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
+ + + 3:   abnormal hormone level [MP:0003953] <15>(27|29) (30|17|8)
+ + + 3:   abnormal blood homeostasis [MP:0009642] <23>(63|82) (70|45|21)
+ + 2:   abnormal circulating hormone level [MP:0005418] <26>(24|23) (25|13|4)
+ + 2:   abnormal insulin-like growth factor I level [MP:0008831] <1>(5|6) (5|5|2)
+ 1:   abnormal circulating insulin-like growth factor I level [MP:0004700] <2>(5|6) (5|5|2)
0:   decreased circulating insulin-like growth factor I level [MP:0004701](2|3) (2|2|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Thyroglobulin type-1 domain0.00009906Direct
Nuclear receptor ligand-binding domain0.0004682Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Thyroglobulin type-1 domain0.00006967Direct
Nuclear receptor0.0003065Direct
Nuclear receptor ligand-binding domain0.0003683Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Thyroglobulin type-1 domain0.00004785Direct
Nuclear receptor ligand-binding domain0.0002461Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
  • 0.0000007798Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.00003908Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)