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Mammalian Phenotype (MP): abnormal vertebral column morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   skeleton phenotype [MP:0005390] <2>(46|63) (50|41|26)
+ + 2:   abnormal skeleton morphology [MP:0005508] <15>(41|59) (47|38|25)
+ 1:   abnormal axial skeleton morphology [MP:0002114] <4>(24|40) (25|21|14)
0:   abnormal vertebral column morphology [MP:0004703] <9>(14|16) (15|11|5)
- 1:   abnormal vertebrae morphology [MP:0000137] <15>(10|10) (11|5|1)
- 1:   abnormal intervertebral disk morphology [MP:0004173] <8>(4|5) (4|3|0)
- 1:   abnormal spine curvature [MP:0004174] <4>(3|4) (3|3|1)
- 1:   abnormal costovertebral joint morphology [MP:0008149] <3>(0|0) (0|0|0)
- 1:   abnormal coccyx morphology [MP:0010114](0|0) (0|0|0)
- 1:   abnormal sacrum morphology [MP:0010113](0|0) (0|0|0)
- 1:   elongated vertebral column [MP:0008771](0|0) (0|0|0)
- 1:   meningomyelocele [MP:0009929](0|0) (0|0|0)
- 1:   short vertebral column [MP:0004704](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
FnI-like domain0.01843Inherited
Glycosyl hydrolase domain0.03011Inherited
Cystine-knot cytokines0.09544Inherited
TIMP-like0.1046Inherited
(Trans)glycosidases0.1482Inherited
SCOP hierarchy in SUPERFAMILY0.2046Inherited
Nuclear receptor ligand-binding domain0.2702Inherited
Clc chloride channel0.2815Inherited
Transducin (alpha subunit), insertion domain0.4107Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.5176Inherited
Kazal-type serine protease inhibitors0.5962Inherited
Homeodomain-like0.6674Inherited
p53-like transcription factors0.8011Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
Extracellular domain of cell surface receptors0.00006343Direct
MBT repeat0.0003634Direct
EF-hand modules in multidomain proteins0.04617Inherited
SAM (sterile alpha motif) domain0.05271Inherited
VWC domain0.05684Inherited
Laminin G-like module0.2306Inherited
Nuclear receptor ligand-binding domain0.2306Inherited
Nuclear receptor0.2306Inherited
Clc chloride channel0.2426Inherited
TB module/8-cys domain0.2426Inherited
T-box0.2808Inherited
Transducin (alpha subunit), insertion domain0.3674Inherited
Bromodomain0.5201Inherited
Homeodomain0.6329Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
FnI-like domain0.01202Inherited
Glycosyl hydrolase domain0.02048Inherited
Cystine-knot cytokines0.07166Inherited
TIMP-like0.07936Inherited
(Trans)glycosidases0.117Inherited
Nuclear receptor ligand-binding domain0.2286Inherited
TB module/8-cys domain0.2394Inherited
Clc chloride channel0.2394Inherited
Transducin (alpha subunit), insertion domain0.364Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4701Inherited
Bromodomain0.5173Inherited
Kazal-type serine protease inhibitors0.5507Inherited
Homeodomain-like0.6249Inherited
p53-like transcription factors0.7663Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.0005593Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.001998Inherited
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0.005066Inherited
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0.02048Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.0285Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.1673Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.2394Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.3638Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4713Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.000301Direct
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.001998Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.08067Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)