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Mammalian Phenotype (MP): limbs/digits/tail phenotype

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   limbs/digits/tail phenotype [MP:0005371] <2>(18|26) (22|21|17)
- 1:   abnormal tail morphology [MP:0002111] <18>(1|3) (2|4|1)
- 1:   abnormal limb morphology [MP:0002109] <13>(12|21) (15|17|16)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Homeodomain-like0.000000001496Direct
Growth factor receptor domain0.0000000343Direct
FnI-like domain0.00001871Direct
p53-like transcription factors0.00005733Direct
EGF/Laminin0.0001097Direct
Frizzled cysteine-rich domain0.0002356Direct
TSP type-3 repeat0.000379Direct
TIMP-like0.0005974Direct
Kringle-like0.01364Inherited
YWTD domain0.01813Inherited
Cystine-knot cytokines0.0292Inherited
Cytokine0.03826Inherited
CalX-like0.03947Inherited
Metalloproteases ("zincins"), catalytic domain0.06597Inherited
PGBD-like0.1283Inherited
Intermediate filament protein, coiled coil region0.1626Inherited
Integrin domains0.2764Inherited
SAM/Pointed domain0.8407Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Homeodomain0.00000001056Direct
Growth factor receptor domain0.000001356Direct
VWC domain0.00002299Direct
Frizzled cysteine-rich domain0.0001474Direct
TSP type-3 repeat0.0002293Direct
Thrombospondin C-terminal domain0.0002293Direct
T-box0.000339Direct
DIX domain0.0009425Direct
HMG-box0.005217Inherited
Transforming growth factor (TGF)-beta0.009871Inherited
Fibroblast growth factors (FGF)0.01005Inherited
Proprotein convertase P-domain0.01071Inherited
Prohormone convertase 1 pro-domain0.01071Inherited
Ovomucoid domain III-like0.01186Inherited
YWTD domain0.01337Inherited
CalX-beta domain0.02983Inherited
Linker histone H1/H50.04333Inherited
Kringle modules0.04908Inherited
Hemopexin-like domain0.07029Inherited
MMP N-terminal domain0.1075Inherited
Matrix metalloproteases, catalytic domain0.1251Inherited
Intermediate filament protein, coiled coil region0.141Inherited
Reprolysin-like0.2113Inherited
SAM (sterile alpha motif) domain0.2297Inherited
Integrin domains0.2483Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Homeodomain-like0.0000000005575Direct
Growth factor receptor domain0.0000000132Direct
FnI-like domain0.000008349Direct
p53-like transcription factors0.00002702Direct
EGF/Laminin0.0000534Direct
Frizzled cysteine-rich domain0.0001195Direct
TSP type-3 repeat0.0001974Direct
TIMP-like0.0003172Direct
HMG-box0.004344Inherited
Kringle-like0.008715Inherited
YWTD domain0.01183Inherited
Cystine-knot cytokines0.0198Inherited
Cytokine0.02646Inherited
CalX-like0.02735Inherited
LDL receptor-like module0.02859Inherited
Metalloproteases ("zincins"), catalytic domain0.04796Inherited
Hemopexin-like domain0.06415Inherited
WD40 repeat-like0.07802Inherited
PGBD-like0.09965Inherited
Intermediate filament protein, coiled coil region0.1297Inherited
Integrin domains0.2345Inherited
SAM/Pointed domain0.809Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.0001974Direct
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001974Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0008267Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0008267Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.000995Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.001064Inherited
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.001264Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.001647Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.002139Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.009611Inherited
    48726,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 0.009611Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.01222Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.01373Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.02568Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.02735Inherited
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0.03443Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.09965Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1463Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.1788Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0000282Direct
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001974Direct
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.0001974Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0006495Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0008267Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0008267Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.001264Inherited
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.002139Inherited
    48726,56436,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.009611Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.009611Inherited
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.009611Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.01825Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.155Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.2372Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4375Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)