SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Mammalian Phenotype (MP): increased alimentary system tumor incidence

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   neoplasm [MP:0002006] <2>(32|37) (38|18|7)
+ + + + 4:   altered tumor susceptibility [MP:0002166] <3>(25|29) (30|11|3)
+ + + 3:   abnormal tumor incidence [MP:0002019] <6>(25|29) (30|11|3)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   digestive/alimentary phenotype [MP:0005381] <2>(38|46) (40|19|9)
+ + 2:   abnormal organ/body region tumor incidence [MP:0013152] <2>(21|24) (24|8|3)
+ + 2:   increased tumor incidence [MP:0002020] <3>(25|27) (30|10|3)
+ 1:   increased organ/body region tumor incidence [MP:0010274] <14>(21|24) (24|8|3)
+ 1:   abnormal digestive system morphology [MP:0000462] <21>(30|38) (31|13|3)
0:   increased alimentary system tumor incidence [MP:0010292] <3>(3|5) (3|2|0)
- 1:   increased gastrointestinal tumor incidence [MP:0010279] <8>(2|3) (2|1|0)
- 1:   increased mouth tumor incidence [MP:0003750] <4>(1|2) (1|1|0)
- 1:   increased esophageal papilloma incidence [MP:0003277](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
DNA repair protein MutS, domain III0.00001037Direct
SMAD MH1 domain0.01629Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
DNA repair protein MutS, domain III0.000006484Direct
SMAD MH1 domain0.01125Inherited
SMAD domain0.01125Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
DNA repair protein MutS, domain III0.000004567Direct
SMAD MH1 domain0.01053Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000004567Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)