SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Mammalian Phenotype (MP): increased skin tumor incidence

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   neoplasm [MP:0002006] <2>(32|37) (38|18|7)
+ + + + + 5:   altered tumor susceptibility [MP:0002166] <3>(25|29) (30|11|3)
+ + + + 4:   abnormal tumor incidence [MP:0002019] <6>(25|29) (30|11|3)
+ + + 3:   increased tumor incidence [MP:0002020] <3>(25|27) (30|10|3)
+ + + 3:   abnormal organ/body region tumor incidence [MP:0013152] <2>(21|24) (24|8|3)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   increased organ/body region tumor incidence [MP:0010274] <14>(21|24) (24|8|3)
+ + 2:   integument phenotype [MP:0010771] <5>(46|64) (53|34|18)
+ 1:   increased integument system tumor incidence [MP:0010293] <3>(4|7) (7|5|2)
+ 1:   abnormal skin morphology [MP:0002060] <16>(19|26) (24|13|8)
0:   increased skin tumor incidence [MP:0010300] <9>(3|3) (6|1|0)
- 1:   increased skin hamartoma incidence [MP:0009469] <1>(1|0) (1|0|0)
- 1:   increased basal cell carcinoma incidence [MP:0004208](0|0) (0|0|0)
- 1:   increased cutaneous melanoma incidence [MP:0010322](0|0) (0|0|0)
- 1:   increased fibrohistocytoma incidence [MP:0002037](0|0) (0|0|0)
- 1:   increased keratoacanthoma incidence [MP:0013488](0|0) (0|0|0)
- 1:   increased pilomatricoma incidence [MP:0002013](0|0) (0|0|0)
- 1:   increased skin papilloma incidence [MP:0002051](1|2) (3|0|0)
- 1:   increased skin squamous cell carcinoma incidence [MP:0009704](0|0) (0|0|0)
- 1:   increased trichoepithelioma incidence [MP:0002732](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
DNA repair protein MutS, domain III0.000002977Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.002821Inherited
Intermediate filament protein, coiled coil region0.1585Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
DNA repair protein MutS, domain III0.000001675Direct
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.004002Inherited
Intermediate filament protein, coiled coil region0.1275Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DNA repair protein MutS, domain III0.000001258Direct
DNA/RNA polymerases0.0007417Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.001631Inherited
Cysteine-rich domain0.006397Inherited
Leucine zipper domain0.03574Inherited
Intermediate filament protein, coiled coil region0.1262Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000001258Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)