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Mammalian Phenotype (MP): abnormal pulmonary acinus morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   respiratory system phenotype [MP:0005388] <2>(33|46) (36|29|15)
+ + + 3:   abnormal respiratory system morphology [MP:0002132] <12>(22|34) (27|22|13)
+ + 2:   abnormal lung morphology [MP:0001175] <18>(15|25) (17|18|12)
+ 1:   abnormal pulmonary alveolar system morphology [MP:0010899] <2>(3|7) (3|10|5)
0:   abnormal pulmonary acinus morphology [MP:0010911] <6>(3|6) (3|8|4)
- 1:   abnormal pulmonary alveolus morphology [MP:0002270] <6>(3|5) (3|6|4)
- 1:   abnormal pulmonary alveolar duct morphology [MP:0002271] <3>(0|0) (0|0|0)
- 1:   abnormal pulmonary interalveolar septum morphology [MP:0010900] <3>(0|0) (0|0|0)
- 1:   abnormal respiratory bronchiole morphology [MP:0004389] <2>(0|0) (0|0|0)
- 1:   abnormal pulmonary alveolar sac morphology [MP:0010902] <1>(0|0) (0|0|0)
- 1:   emphysema [MP:0001958](0|0) (0|3|2)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
FnI-like domain0.007154Inherited
PGBD-like0.01351Inherited
Hemopexin-like domain0.0208Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Short-chain cytokines0.00002326Direct
Hypoxia-inducible factor Hif2a, C-terminal domain0.0005132Direct
MMP N-terminal domain0.01093Inherited
Matrix metalloproteases, catalytic domain0.01284Inherited
Hemopexin-like domain0.01726Inherited
Phosphotyrosine-binding domain (PTB)0.02547Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
FnI-like domain0.004386Inherited
PGBD-like0.008617Inherited
Hemopexin-like domain0.01369Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0001355Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.000532Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0007742Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0008914Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.007223Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.008617Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.01016Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.01795Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0001355Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.000275Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0004838Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.001643Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)