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Mammalian Phenotype (MP): abnormal circulating non-HDL cholesterol level

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + 8:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ + + + 4:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
+ + + + 4:   abnormal lipid homeostasis [MP:0002118] <9>(25|29) (29|17|10)
+ + + 3:   abnormal blood homeostasis [MP:0009642] <23>(63|82) (70|45|21)
+ + + 3:   abnormal cholesterol homeostasis [MP:0005278] <1>(11|12) (13|10|8)
+ + + 3:   abnormal lipid level [MP:0001547] <16>(24|28) (26|16|10)
+ + + 3:   abnormal sterol level [MP:0012224] <5>(11|13) (14|10|8)
+ + 2:   abnormal circulating lipid level [MP:0003949] <9>(16|23) (19|13|10)
+ + 2:   abnormal cholesterol level [MP:0003947] <5>(11|12) (13|10|8)
+ 1:   abnormal circulating cholesterol level [MP:0000180] <4>(9|12) (11|9|8)
0:   abnormal circulating non-HDL cholesterol level [MP:0020151] <2>(5|5) (5|4|5)
- 1:   abnormal circulating LDL cholesterol level [MP:0000181] <2>(5|5) (5|1|0)
- 1:   abnormal circulating VLDL cholesterol level [MP:0005144] <2>(0|0) (0|1|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Multidrug efflux transporter AcrB transmembrane domain0.0001534Direct
Riboflavin synthase domain-like0.04323Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.04323Inherited
Flavoproteins0.04323Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
NADPH-cytochrome p450 reductase-like0.03102Inherited
Pancreatic lipase, N-terminal domain0.03102Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.03102Inherited
Cytochrome p450 reductase N-terminal domain-like0.03102Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Multidrug efflux transporter AcrB transmembrane domain0.00007668Direct
Riboflavin synthase domain-like0.03017Inherited
Flavoproteins0.03017Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.03017Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.000003129Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.004593Inherited
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.03017Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0000199Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0000199Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.004593Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)