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Worm Phenotype (WP): embryonic lethal
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Doublecortin (DC) | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| SMR domain-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Ricin B-like lectins | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| FAD/NAD(P)-binding domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| Tudor/PWWP/MBT | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Pseudouridine synthase | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| BPTI-like | 0 | DIRECT |
| Ganglioside M2 (gm2) activator | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Hairpin loop containing domain-like | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Immunoglobulin | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| p53-like transcription factors | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| alpha-helical ferredoxin | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Actin-crosslinking proteins | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Lipocalins | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
| Glutamine synthetase, N-terminal domain | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Translation proteins SH3-like domain | 0 | DIRECT |
| Leucine zipper domain | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| Osmotin, thaumatin-like protein | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Concanavalin A-like lectins/glucanases | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| SpoIIaa-like | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Tautomerase/MIF | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Cystine-knot cytokines | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| CalX-like | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Nucleic acid-binding proteins | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Serine protease inhibitors | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIc | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Periplasmic binding protein-like I | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| UBA-like | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| RNA-binding domain, RBD | 0.2543 | INHERITED FROM: embryonic lethal late emb |
| ARM repeat | 0.3368 | INHERITED FROM: early embryonic lethal || EMS anterior extension fails early emb || cytokinesis variant emb || failure to hatch |
| TPR-like | 0.3649 | INHERITED FROM: pronucleus centrosomes defective early emb || early embryonic lethal || mitotic spindle defective early emb |
| POZ domain | 0.3824 | INHERITED FROM: excessive blebbing early emb || spindle defective early emb || spindle position orientation defective early emb || cytoplasmic appearance defective early emb || mitotic spindle defective early emb || polar body defective early emb || cytoplasmic dynamics defective early emb || spindle position defective early emb |
| WD40 repeat-like | 0.7283 | INHERITED FROM: cytoplasmic morphology defective early emb || embryonic lethal late emb |
| GTPase activation domain, GAP | 0.7669 | INHERITED FROM: cleavage furrow defective early emb |
| Cyclin-like | 0.7867 | INHERITED FROM: Aba ABp division axis defective early emb || excess pronucleus early emb || multiple cytoplasmic cavities early emb || pronucleus centrosomes defective early emb || early embryonic lethal || chromosome segregation variant karyomeres early emb || pronuclear morphology defective early emb || excess maternal pronucleus early emb || pronuclear size defective early emb |
| "Winged helix" DNA-binding domain | 0.9251 | INHERITED FROM: early embryonic lethal || mitotic spindle defective early emb || passage through meiosis defective early emb |
| P-loop containing nucleoside triphosphate hydrolases | 0.937 | INHERITED FROM: excessive blebbing early emb || cell cell contacts abnormal in four cell embryo || early embryonic lethal || cell cycle timing defective early emb || cytokinesis variant emb || maternal effect lethal emb || cell cycle slow early emb || passage through meiosis defective early emb |
| LuxS/MPP-like metallohydrolase | 0.9497 | INHERITED FROM: embryonic lethal late emb |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9929 | INHERITED FROM: failure to hatch |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: failure to hatch |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Doublecortin (DC) | 0 | Direct |
| Ras GEF | 0 | Direct |
| GAT-like domain | 0 | Direct |
| SMR domain-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Ricin B-like lectins | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| FF domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| ARID-like | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| UBC-like | 0 | Direct |
| Annexin | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| FAD/NAD(P)-binding domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Aldolase | 0 | Direct |
| HCP-like | 0 | Direct |
| DEATH domain | 0 | Direct |
| ADC-like | 0 | Direct |
| PH domain-like | 0 | Direct |
| Tudor/PWWP/MBT | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Tim10-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Pseudouridine synthase | 0 | Direct |
| WWE domain | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| PX domain | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Pentein | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| TAZ domain | 0 | Direct |
| Elafin-like | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| BPTI-like | 0 | Direct |
| Ganglioside M2 (gm2) activator | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| ALDH-like | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| Tropomyosin | 0 | Direct |
| GroES-like | 0 | Direct |
| t-snare proteins | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Hairpin loop containing domain-like | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Lysozyme-like | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| PIN domain-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| Acid proteases | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Sema domain | 0 | Direct |
| Immunoglobulin | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| MIR domain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| WGR domain-like | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| p53-like transcription factors | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| alpha-helical ferredoxin | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Actin-crosslinking proteins | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Nudix | 0 | Direct |
| NHL repeat | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| LEM domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| WW domain | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Lipocalins | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Cupredoxins | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| L domain-like | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| PR-1-like | 0 | Direct |
| Multidrug resistance efflux transporter EmrE | 0 | Direct |
| Glutamine synthetase, N-terminal domain | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| SNARE-like | 0 | Direct |
| DNase I-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Translation proteins SH3-like domain | 0 | Direct |
| Leucine zipper domain | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| CBD9-like | 0 | Direct |
| Kringle-like | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| PUA domain-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| SET domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| SIS domain | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| Osmotin, thaumatin-like protein | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| ACP-like | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| KA1-like | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| MIT domain | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Polo-box domain | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Concanavalin A-like lectins/glucanases | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| GYF domain | 0 | Direct |
| Histone-fold | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| LysM domain | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| BEACH domain | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| SpoIIaa-like | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| ISP domain | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Nop domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| HIT-like | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Tautomerase/MIF | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| SAP domain | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| DNA clamp | 0 | Direct |
| Cystine-knot cytokines | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| BSD domain-like | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| BolA-like | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| eIF1-like | 0 | Direct |
| CalX-like | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Nucleic acid-binding proteins | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Kelch motif | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| Flavoproteins | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| TIMP-like | 0 | Direct |
| SAND domain-like | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| Translation proteins | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| PGBD-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Caspase-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Mss4-like | 0 | Direct |
| HMG-box | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Serine protease inhibitors | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| SH3-domain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIc | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Periplasmic binding protein-like I | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| TGS-like | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| HAD-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Bet v1-like | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| L30e-like | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| UBA-like | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| SCP-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| YbiA-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| R3H domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| RNA-binding domain, RBD | 0.2543 | Inherited |
| ARM repeat | 0.3368 | Inherited |
| TPR-like | 0.3649 | Inherited |
| POZ domain | 0.3824 | Inherited |
| WD40 repeat-like | 0.7283 | Inherited |
| GTPase activation domain, GAP | 0.7669 | Inherited |
| Cyclin-like | 0.7867 | Inherited |
| "Winged helix" DNA-binding domain | 0.9251 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.937 | Inherited |
| LuxS/MPP-like metallohydrolase | 0.9497 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9929 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| Tudor domain | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Aldo-keto reductases (NADP) | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Ephrin ectodomain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| Autophagin-like | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | DIRECT |
| beta-glycanases | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| H-NOX domain | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Purple acid phosphatase-like | 0 | DIRECT |
| Arylamine N-methyltransferase | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Integrin A (or I) domain | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Patatin | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| FAD/NAD-linked reductases, N-terminal and central domains | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| Internalin LRR domain | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Cyclophilin (peptidylprolyl isomerase) | 0 | DIRECT |
| Pseudouridine synthase I TruA | 0 | DIRECT |
| Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| PEP carboxykinase C-terminal domain | 0 | DIRECT |
| L-arabinose binding protein-like | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Laminin-type module | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| La domain | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| F-box domain | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| T-box | 0 | DIRECT |
| Brix domain | 0 | DIRECT |
| Glycerol-3-phosphate transporter | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| Transforming growth factor (TGF)-beta | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| Nucleosome core histones | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Heme-dependent catalases | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Pepsin-like | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| GABA-aminotransferase-like | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| FabD-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| Fungal lipases | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Cytochrome b5 | 0 | DIRECT |
| Fatty acid binding protein-like | 0 | DIRECT |
| Astacin | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| Ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| TBP-associated factors, TAFs | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Rv2717c-like | 0 | DIRECT |
| NADPH-cytochrome p450 reductase-like | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| 28-residue LRR | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| Carboxylesterase | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| RUN domain | 0 | DIRECT |
| Ribonuclease H | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| Ganglioside M2 (gm2) activator | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| SPRY domain | 0 | DIRECT |
| HSP20 | 0 | DIRECT |
| Bacterial lipase | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| RIO1-like kinases | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| Diap1 N-terninal region-like | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| Vertebrate phospholipase A2 | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Small Kunitz-type inhibitors & BPTI-like toxins | 0 | DIRECT |
| GAS2 domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
| Smr domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| L domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| STAR domain | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| Globins | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| N-acetyl transferase, NAT | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| Acireductone dioxygenase | 0 | DIRECT |
| PhzC/PhzF-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Ricin B-like | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| Osmotin, thaumatin-like protein | 0 | DIRECT |
| Cadherin | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| CalX-beta domain | 0 | DIRECT |
| MFPT repeat | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| PDZ domain | 0 | DIRECT |
| RING finger domain, C3HC4 | 0 | DIRECT |
| Acyl-CoA thioesterase | 0 | DIRECT |
| PhyH-like | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Nucleotide and nucleoside kinases | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| N-acetylglucosaminyltransferase I | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| Nitrogenase iron protein-like | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Mammalian PLC | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| BTB/POZ domain | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| ATI-like | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| AraD-like aldolase/epimerase | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| AlkB-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| CoA transferase alpha subunit-like | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| LacY-like proton/sugar symporter | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Papain-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| Cell cycle transcription factor e2f-dp | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Galectin (animal S-lectin) | 0 | DIRECT |
| MIF-related | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| Hermes transposase-like | 0 | DIRECT |
| Gastric lipase | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| Glutamine synthetase, N-terminal domain | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| Tetramerization domain of potassium channels | 0 | DIRECT |
| Trehalase-like | 0 | DIRECT |
| Gelsolin-like | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| AMPK-beta glycogen binding domain-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| Ubiquitin-related | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Hemocyanin middle domain | 0 | DIRECT |
| Elongation factors | 0 | DIRECT |
| beta-CASP RNA-metabolising hydrolases | 0 | DIRECT |
| Pyridoxal-dependent decarboxylase | 0 | DIRECT |
| NLI interacting factor-like phosphatase | 0 | DIRECT |
| Classic zinc finger, C2H2 | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Leucine zipper domain | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| LIM domain | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| Glutamine synthetase catalytic domain | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| BSD domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| YihX-like | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Cold shock DNA-binding domain-like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Synaptotagmin-like (S variant) | 0 | DIRECT |
| Multidomain sulfurtransferase (rhodanese) | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| EF-hand modules in multidomain proteins | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Family 19 glycosidase | 0 | DIRECT |
| UBX domain | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| CoA-binding domain | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| RNA methyltransferase FtsJ | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| PaaI/YdiI-like | 0 | DIRECT |
| Cdc48 N-terminal domain-like | 0 | DIRECT |
| Mo25 protein | 0 | DIRECT |
| Catalytic, N-terminal domain of histone methyltransferase Dot1l | 0 | DIRECT |
| Filamin repeat (rod domain) | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| Aminomethyltransferase folate-binding domain | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| I set domains | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Leukotriene A4 hydrolase catalytic domain | 0 | DIRECT |
| TatD Mg-dependent DNase-like | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| UDPGT-like | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| ZZ domain | 0 | DIRECT |
| Caspase catalytic domain | 0 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| NagD-like | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| Canonical RBD | 0.3339 | INHERITED FROM: embryonic lethal late emb |
| G proteins | 0.5203 | INHERITED FROM: spindle position orientation defective early emb || early embryonic lethal || cytokinesis variant emb || mitotic spindle defective early emb |
| Protein serine/threonine phosphatase | 0.6143 | INHERITED FROM: meiosis defective early emb |
| Extended AAA-ATPase domain | 0.6625 | INHERITED FROM: ectopic cleavage furrow early emb || excessive blebbing early emb || cell cell contacts abnormal in four cell embryo || multiple cytoplasmic cavities early emb || meiosis defective early emb || early embryonic lethal || relative cell cycle timing defective early emb || cell cycle timing defective early emb || cytokinesis variant emb || meiotic spindle defective early emb || one cell arrest early emb || passage through meiosis defective early emb |
| Motor proteins | 0.6886 | INHERITED FROM: cleavage furrow defective early emb || spindle defective early emb || pronucleus centrosomes defective early emb || early embryonic lethal || cytokinesis variant emb || passage through meiosis defective early emb |
| BCR-homology GTPase activation domain (BH-domain) | 0.8353 | INHERITED FROM: cleavage furrow defective early emb |
| Cyclin | 0.876 | INHERITED FROM: Aba ABp division axis defective early emb || excess pronucleus early emb || multiple cytoplasmic cavities early emb || pronucleus centrosomes defective early emb || early embryonic lethal || chromosome segregation variant karyomeres early emb || pronuclear morphology defective early emb || excess maternal pronucleus early emb || pronuclear size defective early emb |
| WD40-repeat | 0.8905 | INHERITED FROM: cytoplasmic morphology defective early emb || embryonic lethal late emb |
| MPP-like | 0.9399 | INHERITED FROM: embryonic lethal late emb |
| Nuclear receptor | 1 | INHERITED FROM: failure to hatch |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: failure to hatch |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| Tudor domain | 0 | Direct |
| GAPDH-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Aldo-keto reductases (NADP) | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| PDI-like | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Ephrin ectodomain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| CAT-like | 0 | Direct |
| Autophagin-like | 0 | Direct |
| Reductases | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Prefoldin | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | Direct |
| beta-glycanases | 0 | Direct |
| BAR domain | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| MIR domain | 0 | Direct |
| H-NOX domain | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Purple acid phosphatase-like | 0 | Direct |
| Arylamine N-methyltransferase | 0 | Direct |
| SAP domain | 0 | Direct |
| Integrin A (or I) domain | 0 | Direct |
| FCH domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Patatin | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| FAD/NAD-linked reductases, N-terminal and central domains | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Nop domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| Internalin LRR domain | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Cyclophilin (peptidylprolyl isomerase) | 0 | Direct |
| Pseudouridine synthase I TruA | 0 | Direct |
| Phosphotyrosine-binding domain (PTB) | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Meta-cation ATPase, catalytic domain P | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| PEP carboxykinase C-terminal domain | 0 | Direct |
| L-arabinose binding protein-like | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Laminin-type module | 0 | Direct |
| UBC-related | 0 | Direct |
| Crotonase-like | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| La domain | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| TAZ domain | 0 | Direct |
| F-box domain | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Annexin | 0 | Direct |
| T-box | 0 | Direct |
| Brix domain | 0 | Direct |
| Glycerol-3-phosphate transporter | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| WW domain | 0 | Direct |
| Transforming growth factor (TGF)-beta | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| Nucleosome core histones | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Heme-dependent catalases | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| PX domain | 0 | Direct |
| Pepsin-like | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| WGR domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| SWIRM domain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| GABA-aminotransferase-like | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| First domain of FERM | 0 | Direct |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| FF domain | 0 | Direct |
| Cullin repeat | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| CUT domain | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| FabD-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| PR-1-like | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| Fungal lipases | 0 | Direct |
| SMAD domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Cytochrome b5 | 0 | Direct |
| Fatty acid binding protein-like | 0 | Direct |
| Astacin | 0 | Direct |
| ARID domain | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| Ferredoxin domains from multidomain proteins | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| TBP-associated factors, TAFs | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| WWE domain | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Rv2717c-like | 0 | Direct |
| NADPH-cytochrome p450 reductase-like | 0 | Direct |
| Ras GEF | 0 | Direct |
| 28-residue LRR | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| Carboxylesterase | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Sema domain | 0 | Direct |
| RUN domain | 0 | Direct |
| Ribonuclease H | 0 | Direct |
| COMT-like | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Hexokinase | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| Ganglioside M2 (gm2) activator | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| SPRY domain | 0 | Direct |
| HSP20 | 0 | Direct |
| Bacterial lipase | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| PUA domain | 0 | Direct |
| U-box | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| RIO1-like kinases | 0 | Direct |
| Tetraspanin | 0 | Direct |
| Subtilases | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| Diap1 N-terninal region-like | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| MutT-like | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| Vertebrate phospholipase A2 | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Small Kunitz-type inhibitors & BPTI-like toxins | 0 | Direct |
| GAS2 domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Glycogenin | 0 | Direct |
| D-aminoacid oxidase, N-terminal domain | 0 | Direct |
| Smr domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| L domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| STAR domain | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Phoshatidylinositol transfer protein, PITP | 0 | Direct |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| Globins | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| GYF domain | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| N-acetyl transferase, NAT | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| Acireductone dioxygenase | 0 | Direct |
| PhzC/PhzF-like | 0 | Direct |
| LysM domain | 0 | Direct |
| Ricin B-like | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| Osmotin, thaumatin-like protein | 0 | Direct |
| Cadherin | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| CalX-beta domain | 0 | Direct |
| MFPT repeat | 0 | Direct |
| Sec7 domain | 0 | Direct |
| PDZ domain | 0 | Direct |
| RING finger domain, C3HC4 | 0 | Direct |
| Acyl-CoA thioesterase | 0 | Direct |
| PhyH-like | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| Kelch motif | 0 | Direct |
| Nucleotide and nucleoside kinases | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| N-acetylglucosaminyltransferase I | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| Nitrogenase iron protein-like | 0 | Direct |
| MIT domain | 0 | Direct |
| Mammalian PLC | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Paired domain | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| Chromo domain | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| BTB/POZ domain | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| HEAT repeat | 0 | Direct |
| ATI-like | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| LEM domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| DEP domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| AraD-like aldolase/epimerase | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| eIF1-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| BolA-like | 0 | Direct |
| AlkB-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| CoA transferase alpha subunit-like | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| LacY-like proton/sugar symporter | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Troponin I | 0 | Direct |
| Adenain-like | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Papain-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
| Tropomyosin | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| IF2B-like | 0 | Direct |
| Cell cycle transcription factor e2f-dp | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Galectin (animal S-lectin) | 0 | Direct |
| MIF-related | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
| Class I aldolase | 0 | Direct |
| Hermes transposase-like | 0 | Direct |
| Gastric lipase | 0 | Direct |
| VHS domain | 0 | Direct |
| Glutamine synthetase, N-terminal domain | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| Tetramerization domain of potassium channels | 0 | Direct |
| Trehalase-like | 0 | Direct |
| Gelsolin-like | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| AMPK-beta glycogen binding domain-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| Ubiquitin-related | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Hemocyanin middle domain | 0 | Direct |
| Elongation factors | 0 | Direct |
| beta-CASP RNA-metabolising hydrolases | 0 | Direct |
| Pyridoxal-dependent decarboxylase | 0 | Direct |
| NLI interacting factor-like phosphatase | 0 | Direct |
| Classic zinc finger, C2H2 | 0 | Direct |
| YbiA-like | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Leucine zipper domain | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Integrin domains | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| LIM domain | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| SH3-domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| PDEase | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| Choline kinase | 0 | Direct |
| Elafin-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| ets domain | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| PP2C-like | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| Glutamine synthetase catalytic domain | 0 | Direct |
| Glutaminase | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| BSD domain | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| YihX-like | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| HMG-box | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Cold shock DNA-binding domain-like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Synaptotagmin-like (S variant) | 0 | Direct |
| Multidomain sulfurtransferase (rhodanese) | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| EF-hand modules in multidomain proteins | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Family 19 glycosidase | 0 | Direct |
| UBX domain | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| CoA-binding domain | 0 | Direct |
| UBA domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| FHA domain | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| RNA methyltransferase FtsJ | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| PaaI/YdiI-like | 0 | Direct |
| Cdc48 N-terminal domain-like | 0 | Direct |
| Mo25 protein | 0 | Direct |
| Catalytic, N-terminal domain of histone methyltransferase Dot1l | 0 | Direct |
| Filamin repeat (rod domain) | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| Aminomethyltransferase folate-binding domain | 0 | Direct |
| HD domain | 0 | Direct |
| SAND domain | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| I set domains | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Leukotriene A4 hydrolase catalytic domain | 0 | Direct |
| TatD Mg-dependent DNase-like | 0 | Direct |
| NHL repeat | 0 | Direct |
| UDPGT-like | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| Plexin repeat | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| ZZ domain | 0 | Direct |
| Caspase catalytic domain | 0 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| NagD-like | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| Canonical RBD | 0.3339 | Inherited |
| G proteins | 0.5203 | Inherited |
| Protein serine/threonine phosphatase | 0.6143 | Inherited |
| Extended AAA-ATPase domain | 0.6625 | Inherited |
| Motor proteins | 0.6886 | Inherited |
| BCR-homology GTPase activation domain (BH-domain) | 0.8353 | Inherited |
| Cyclin | 0.876 | Inherited |
| WD40-repeat | 0.8905 | Inherited |
| MPP-like | 0.9399 | Inherited |
| Nuclear receptor | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Mss4-like | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Concanavalin A-like lectins/glucanases | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Ganglioside M2 (gm2) activator | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Translation proteins SH3-like domain | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| UBA-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| Pseudouridine synthase | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Actin-crosslinking proteins | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| Hairpin loop containing domain-like | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| BPTI-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| Immunoglobulin | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| CalX-like | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| SMR domain-like | 0 | DIRECT |
| Cystine-knot cytokines | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| Ricin B-like lectins | 0 | DIRECT |
| Nucleic acid-binding proteins | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Serine protease inhibitors | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Leucine zipper domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| alpha-helical ferredoxin | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIc | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Glutamine synthetase, N-terminal domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Lipocalins | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| p53-like transcription factors | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Periplasmic binding protein-like I | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
| Tautomerase/MIF | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| FAD/NAD(P)-binding domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Osmotin, thaumatin-like protein | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| Tudor/PWWP/MBT | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| SpoIIaa-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| RNA-binding domain, RBD | 0.2364 | INHERITED FROM: embryonic lethal late emb |
| ARM repeat | 0.3171 | INHERITED FROM: EMS anterior extension fails early emb || early embryonic lethal || cytokinesis variant emb || failure to hatch |
| TPR-like | 0.3445 | INHERITED FROM: pronucleus centrosomes defective early emb || mitotic spindle defective early emb || early embryonic lethal |
| POZ domain | 0.3619 | INHERITED FROM: polar body defective early emb || cytoplasmic appearance defective early emb || spindle defective early emb || spindle position orientation defective early emb || mitotic spindle defective early emb || excessive blebbing early emb || spindle position defective early emb || cytoplasmic dynamics defective early emb |
| WD40 repeat-like | 0.708 | INHERITED FROM: embryonic lethal late emb || cytoplasmic morphology defective early emb |
| GTPase activation domain, GAP | 0.7478 | INHERITED FROM: cleavage furrow defective early emb |
| Cyclin-like | 0.7681 | INHERITED FROM: multiple cytoplasmic cavities early emb || pronuclear morphology defective early emb || excess maternal pronucleus early emb || pronuclear size defective early emb || Aba ABp division axis defective early emb || pronucleus centrosomes defective early emb || excess pronucleus early emb || chromosome segregation variant karyomeres early emb || early embryonic lethal |
| "Winged helix" DNA-binding domain | 0.9108 | INHERITED FROM: mitotic spindle defective early emb || passage through meiosis defective early emb || early embryonic lethal |
| P-loop containing nucleoside triphosphate hydrolases | 0.9232 | INHERITED FROM: cell cell contacts abnormal in four cell embryo || maternal effect lethal emb || cell cycle timing defective early emb || excessive blebbing early emb || passage through meiosis defective early emb || early embryonic lethal || cytokinesis variant emb || cell cycle slow early emb |
| LuxS/MPP-like metallohydrolase | 0.9365 | INHERITED FROM: embryonic lethal late emb |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9824 | INHERITED FROM: failure to hatch |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: failure to hatch |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Mss4-like | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| SAP domain | 0 | Direct |
| HMG-box | 0 | Direct |
| PH domain-like | 0 | Direct |
| HAD-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| NTF2-like | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| ALDH-like | 0 | Direct |
| Concanavalin A-like lectins/glucanases | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| SNARE-like | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| KA1-like | 0 | Direct |
| Ganglioside M2 (gm2) activator | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Sema domain | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| Elafin-like | 0 | Direct |
| Translation proteins SH3-like domain | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| UBA-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| PUA domain-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Tim10-like | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| L domain-like | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| SH3-domain | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| Pseudouridine synthase | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| BSD domain-like | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| Nudix | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Actin-crosslinking proteins | 0 | Direct |
| ARID-like | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| Lysozyme-like | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| Hairpin loop containing domain-like | 0 | Direct |
| PGBD-like | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| TAZ domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| Integrin domains | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| PIN domain-like | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| LEM domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| LysM domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| CBD9-like | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| YbiA-like | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| SET domain | 0 | Direct |
| WW domain | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| L30e-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| RUN domain-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| DNA clamp | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| BPTI-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Kelch motif | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| MIT domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cupredoxins | 0 | Direct |
| Immunoglobulin | 0 | Direct |
| Aldolase | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| CalX-like | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| HCP-like | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| SMR domain-like | 0 | Direct |
| Cystine-knot cytokines | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| VPS9 domain | 0 | Direct |
| BolA-like | 0 | Direct |
| TIMP-like | 0 | Direct |
| Ricin B-like lectins | 0 | Direct |
| Nucleic acid-binding proteins | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| Flavoproteins | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Serine protease inhibitors | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| GroES-like | 0 | Direct |
| Bet v1-like | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Leucine zipper domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| alpha-helical ferredoxin | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| BEACH domain | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIc | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| eIF1-like | 0 | Direct |
| FF domain | 0 | Direct |
| Glutamine synthetase, N-terminal domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| NHL repeat | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| Kringle-like | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Lipocalins | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| DNase I-like | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| SCP-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Nop domain | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Translation proteins | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| p53-like transcription factors | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Caspase-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| ISP domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| PR-1-like | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| SIS domain | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Periplasmic binding protein-like I | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Cytochrome c | 0 | Direct |
| UBC-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| HIT-like | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| DEATH domain | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Acid proteases | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| MIR domain | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| ACP-like | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| SAND domain-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Pentein | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| TGS-like | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Multidrug resistance efflux transporter EmrE | 0 | Direct |
| Tautomerase/MIF | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| PX domain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| PP2C-like | 0 | Direct |
| GYF domain | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| FAD/NAD(P)-binding domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Osmotin, thaumatin-like protein | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| Ras GEF | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Histone-fold | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| Tudor/PWWP/MBT | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| SpoIIaa-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| PEBP-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| WWE domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| ADC-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| RNA-binding domain, RBD | 0.2364 | Inherited |
| ARM repeat | 0.3171 | Inherited |
| TPR-like | 0.3445 | Inherited |
| POZ domain | 0.3619 | Inherited |
| WD40 repeat-like | 0.708 | Inherited |
| GTPase activation domain, GAP | 0.7478 | Inherited |
| Cyclin-like | 0.7681 | Inherited |
| "Winged helix" DNA-binding domain | 0.9108 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.9232 | Inherited |
| LuxS/MPP-like metallohydrolase | 0.9365 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9824 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54368,55931
54368 - Glutamine synthetase, N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | DIRECT |
52374,52374
52374 - Nucleotidylyl transferase
52374 - Nucleotidylyl transferase | 0 | DIRECT |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
141072,141072
141072 - CalX-like
141072 - CalX-like | 0 | DIRECT |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | DIRECT |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
49599,54695
49599 - TRAF domain-like
54695 - POZ domain | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | DIRECT |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
51126,51126
51126 - Pectin lyase-like
51126 - Pectin lyase-like | 0 | DIRECT |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
48403,52113
48403 - Ankyrin repeat
52113 - BRCT domain | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | DIRECT |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
54495,57850
54495 - UBC-like
57850 - RING/U-box | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
49363,56300
49363 - Purple acid phosphatase, N-terminal domain
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
52821,52821
52821 - Rhodanese/Cell cycle control phosphatase
52821 - Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0.9365 | INHERITED FROM: embryonic lethal late emb |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: meiotic spindle defective early emb |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54368,55931
54368 - Glutamine synthetase, N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | Direct |
52374,52374
52374 - Nucleotidylyl transferase
52374 - Nucleotidylyl transferase | 0 | Direct |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
141072,141072
141072 - CalX-like
141072 - CalX-like | 0 | Direct |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | Direct |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
49599,54695
49599 - TRAF domain-like
54695 - POZ domain | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | Direct |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
51126,51126
51126 - Pectin lyase-like
51126 - Pectin lyase-like | 0 | Direct |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
48403,52113
48403 - Ankyrin repeat
52113 - BRCT domain | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | Direct |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
54495,57850
54495 - UBC-like
57850 - RING/U-box | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
49363,56300
49363 - Purple acid phosphatase, N-terminal domain
56300 - Metallo-dependent phosphatases | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
52821,52821
52821 - Rhodanese/Cell cycle control phosphatase
52821 - Rhodanese/Cell cycle control phosphatase | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0.9365 | Inherited |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49599,49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
90257,90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49599,49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
90257,90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
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