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Worm Phenotype (WP): behavior variant
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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0.0000000000001202 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0.0000000000006711 | DIRECT |
| HSP20-like chaperones | 0.00000000001145 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.00000000004973 | DIRECT |
| Histone-fold | 0.0000000001923 | DIRECT |
| Periplasmic binding protein-like I | 0.000000001853 | DIRECT |
| Nucleotide cyclase | 0.000000005384 | DIRECT |
| Homeodomain-like | 0.000000008673 | DIRECT |
| Insulin-like | 0.000000009713 | DIRECT |
| ARM repeat | 0.0000003995 | DIRECT |
| TPR-like | 0.000001038 | DIRECT |
| Band 7/SPFH domain | 0.000003688 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.000005834 | DIRECT |
| Bromodomain | 0.000005837 | DIRECT |
| "Winged helix" DNA-binding domain | 0.00001155 | DIRECT |
| Actin-like ATPase domain | 0.00001593 | DIRECT |
| GroEL-intermediate domain like | 0.00001981 | DIRECT |
| GroEL equatorial domain-like | 0.00001981 | DIRECT |
| Sm-like ribonucleoproteins | 0.00002453 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.00002697 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0.00002976 | DIRECT |
| Tubulin C-terminal domain-like | 0.00007093 | DIRECT |
| Nicotinic receptor ligand binding domain-like | 0.0001294 | DIRECT |
| GroEL apical domain-like | 0.0001422 | DIRECT |
| SNF-like | 0.0002005 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0.0002005 | DIRECT |
| PH domain-like | 0.0002013 | DIRECT |
| SMAD/FHA domain | 0.0003064 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.0003855 | DIRECT |
| RNA-binding domain, RBD | 0.0004119 | DIRECT |
| Growth factor receptor domain | 0.0004808 | DIRECT |
| Tropomyosin | 0.0005615 | DIRECT |
| Immunoglobulin | 0.0007898 | DIRECT |
| Class II aaRS and biotin synthetases | 0.0009023 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0.000942 | DIRECT |
| Cysteine-rich domain | 0.001457 | INHERITED FROM: thermosensory behavior variant || odorant chemosensory response variant || eating variant || odorant positive chemotaxis variant || positive chemotaxis variant || thermotaxis variant |
| Prefoldin | 0.001486 | INHERITED FROM: locomotion variant |
| Hedgehog/intein (Hint) domain | 0.001665 | INHERITED FROM: movement variant || locomotion variant |
| Protein kinase-like (PK-like) | 0.003053 | INHERITED FROM: aqueous chemosensory response variant || postembryonic behavior variant || organism region behavior variant || dauer nictation behavior variant || chemosensory behavior variant || egg laying response to food variant || velocity of movement increased || body muscle dystrophy || positive chemotaxis variant || alkaline pH chemotaxis variant || mechanosensation variant || developmental behavior variant || dauer behavior variant || octanol chemotaxis defective || organism segment behavior variant || late stage egg laid |
| NAD(P)-linked oxidoreductase | 0.003219 | INHERITED FROM: defecation cycle variant || defecation variant |
| Voltage-gated potassium channels | 0.003228 | INHERITED FROM: hyperactive egg laying || spicule insertion defective || egg laying defective || backward point velocity variant || body bend variant || backward locomotion variant || body posture variant || head bend angle variant || eating variant || localized movement variant || positive chemotaxis defective || plate tap habituation variant || turning frequency variant || forward locomotion variant || expulsion defective || expulsion variant || habituation variant || forward point velocity variant || locomotor coordination variant || coiling frequency variant || tail bend angle variant || mechanosensation variant || roller || bag of worms || bloated || flaccid || activity level variant || head movement variant |
| F1F0 ATP synthase subunit C | 0.00332 | INHERITED FROM: avoids bacterial lawn |
| ARID-like | 0.00332 | INHERITED FROM: light response variant || organism UV hypersensitive || organism UV response variant |
| S15/NS1 RNA-binding domain | 0.00332 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| Frizzled cysteine-rich domain | 0.00332 | INHERITED FROM: organism region behavior variant || body behavior variant || body muscle dystrophy || organism segment behavior variant |
| Nucleic acid-binding proteins | 0.003527 | INHERITED FROM: avoids bacterial lawn |
| Spectrin repeat | 0.004391 | INHERITED FROM: movement variant || locomotion variant |
| Zn-binding ribosomal proteins | 0.004609 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| cAMP-binding domain-like | 0.007763 | INHERITED FROM: thermosensory behavior variant || odorant chemosensory response variant || frequency of body bend variant || egg laying defective || body posture wavelength variant || backward point velocity variant || body bend variant || odorant negative chemotaxis defective || male mating variant || chemosensory behavior variant || head bend angle variant || male mating defective || benzaldehyde chemotaxis defective || odorant positive chemotaxis variant || coiling variant || positive chemotaxis variant || positive chemotaxis defective || turning frequency variant || butanone chemotaxis variant || forward point velocity variant || sodium chloride chemotaxis defective || chemotaxis variant || thermotaxis variant || odorant positive chemotaxis defective || coiling frequency variant || directionality variant || roller || nose movement variant || bloated || body posture amplitude variant || path curvature variant || sodium chloride chemotaxis variant || turning variant || benzaldehyde chemotaxis variant || head movement variant || amplitude of sinusoidal movement variant |
| Translation proteins SH3-like domain | 0.009521 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| EGF/Laminin | 0.01004 | INHERITED FROM: odorant negative chemotaxis defective || movement variant || locomotion variant || octanol chemotaxis variant || octanol chemotaxis defective |
| E2F-DP heterodimerization region | 0.01142 | INHERITED FROM: backward locomotion variant || locomotor coordination variant || reversal variant || directionality variant |
| Cu,Zn superoxide dismutase-like | 0.01142 | INHERITED FROM: defecation cycle variant || defecation cycle variable length || defecation variant |
| Integrin domains | 0.01142 | INHERITED FROM: egg laying variant |
| PYP-like sensor domain (PAS domain) | 0.01311 | INHERITED FROM: egg laying defective || egg laying variant |
| WD40 repeat-like | 0.01763 | INHERITED FROM: osmotic avoidance variant |
| PLC-like phosphodiesterases | 0.01794 | INHERITED FROM: spicule insertion defective || male mating variant || sexually dimorphic behavior variant || male mating defective || posterior body wall contraction defecation cycle variant || ovulation variant || defecation variant || defecation contraction variant || copulation variant |
| Fibronectin type III | 0.01908 | INHERITED FROM: body posture variant || forward locomotion decreased || reversal variant || path curvature increased || locomotion reduced |
| Intermediate filament protein, coiled coil region | 0.02274 | INHERITED FROM: paralyzed |
| Lamin A/C globular tail domain | 0.02274 | INHERITED FROM: paralyzed |
| Arginase/deacetylase | 0.02839 | INHERITED FROM: light response variant || organism UV hypersensitive || organism UV response variant |
| SH3-domain | 0.03064 | INHERITED FROM: ovulation variant |
| FYVE/PHD zinc finger | 0.03139 | INHERITED FROM: light response variant || organism UV hypersensitive || organism UV response variant |
| Periplasmic binding protein-like II | 0.04841 | INHERITED FROM: thermosensory behavior variant || aqueous positive chemotaxis defective || chemosensory behavior variant || eating variant || positive chemotaxis defective || sodium chloride chemotaxis defective || chemotaxis variant || thermotaxis variant || pharyngeal pumping reduced || pharyngeal pumping rate variant || aqueous positive chemotaxis variant || sodium chloride chemotaxis variant || chemosensory response variant |
| beta-beta-alpha zinc fingers | 0.04847 | INHERITED FROM: egg laying imipramine resistant |
| FKBP-like | 0.05182 | INHERITED FROM: postembryonic behavior variant || developmental behavior variant || dauer behavior variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.05182 | INHERITED FROM: eating variant || pharyngeal pumping rate variant || induced pharyngeal pumping variant |
| HD-domain/PDEase-like | 0.05182 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant |
| DNA/RNA polymerases | 0.06367 | INHERITED FROM: light response variant || organism UV hypersensitive || organism UV response variant |
| Class II aaRS ABD-related | 0.06728 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.08391 | INHERITED FROM: avoids bacterial lawn |
| Lipovitellin-phosvitin complex, superhelical domain | 0.08645 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.08645 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| PDZ domain-like | 0.09133 | INHERITED FROM: organism region behavior variant || body behavior variant || body muscle dystrophy || ovulation variant || organism segment behavior variant |
| NTF2-like | 0.1032 | INHERITED FROM: male mating variant || male mating defective |
| Nucleotidylyl transferase | 0.1048 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| Thiamin diphosphate-binding fold (THDP-binding) | 0.1112 | INHERITED FROM: avoids bacterial lawn |
| Myosin rod fragments | 0.1112 | INHERITED FROM: sluggish |
| L30e-like | 0.1112 | INHERITED FROM: avoids bacterial lawn |
| Regulator of G-protein signaling, RGS | 0.1348 | INHERITED FROM: negative chemotaxis variant || chemotaxis variant || mechanosensation variant |
| Glutathione synthetase ATP-binding domain-like | 0.1703 | INHERITED FROM: male mating variant || chemosensory behavior variant || sexually dimorphic behavior variant || male mating efficiency reduced || negative chemotaxis variant || osmotic avoidance variant || chemotaxis variant || copulation variant |
| EF-hand | 0.202 | INHERITED FROM: ovulation variant || defecation contraction variant |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.2099 | INHERITED FROM: defecation cycle variant || defecation variant |
| Acyl-CoA dehydrogenase NM domain-like | 0.2099 | INHERITED FROM: defecation cycle variant || defecation variant |
| Chromo domain-like | 0.2164 | INHERITED FROM: light response variant || organism UV hypersensitive || organism UV response variant |
| PLP-dependent transferases | 0.3029 | INHERITED FROM: path curvature decreased || forward locomotion increased || expulsion variant || body posture amplitude increased || defecation contraction variant |
| NAD kinase/diacylglycerol kinase-like | 0.3829 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant |
| Ubiquitin-like | 0.3896 | INHERITED FROM: organism region behavior variant || body behavior variant || body muscle dystrophy || organism segment behavior variant |
| LDL receptor-like module | 0.4137 | INHERITED FROM: paralyzed |
| Ankyrin repeat | 0.4982 | INHERITED FROM: body bend variant || odorant negative chemotaxis defective || body posture wavelength decreased || backward locomotion variant || sinusoidal movement variant || body posture variant || head bend angle variant || localized movement variant || turning frequency variant || forward locomotion variant || chemotaxis variant || reversal variant || tail bend angle variant || octanol chemotaxis variant || nose movement variant || octanol chemotaxis defective || turning variant || chemosensory response variant || tail movement variant || head movement variant |
| FAD/NAD(P)-binding domain | 0.6845 | INHERITED FROM: fewer eggs laid |
| BPTI-like | 0.7446 | INHERITED FROM: male mating defective |
| Saposin | 0.8202 | INHERITED FROM: fewer eggs laid |
| C-type lectin-like | 1 | INHERITED FROM: male mating variant || sexually dimorphic behavior variant || male mating defective || copulation variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | INHERITED FROM: solitary feeding increased |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: serotonin induced pumping variant || induced pharyngeal pumping variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: solitary feeding increased |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Cytochrome c | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0.0000000000001202 | Direct |
| Transducin (alpha subunit), insertion domain | 0.0000000000006711 | Direct |
| HSP20-like chaperones | 0.00000000001145 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.00000000004973 | Direct |
| Histone-fold | 0.0000000001923 | Direct |
| Periplasmic binding protein-like I | 0.000000001853 | Direct |
| Nucleotide cyclase | 0.000000005384 | Direct |
| Homeodomain-like | 0.000000008673 | Direct |
| Insulin-like | 0.000000009713 | Direct |
| ARM repeat | 0.0000003995 | Direct |
| TPR-like | 0.000001038 | Direct |
| Band 7/SPFH domain | 0.000003688 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.000005834 | Direct |
| Bromodomain | 0.000005837 | Direct |
| "Winged helix" DNA-binding domain | 0.00001155 | Direct |
| Actin-like ATPase domain | 0.00001593 | Direct |
| GroEL-intermediate domain like | 0.00001981 | Direct |
| GroEL equatorial domain-like | 0.00001981 | Direct |
| Sm-like ribonucleoproteins | 0.00002453 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.00002697 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0.00002976 | Direct |
| Tubulin C-terminal domain-like | 0.00007093 | Direct |
| Nicotinic receptor ligand binding domain-like | 0.0001294 | Direct |
| GroEL apical domain-like | 0.0001422 | Direct |
| SNF-like | 0.0002005 | Direct |
| Tubulin nucleotide-binding domain-like | 0.0002005 | Direct |
| PH domain-like | 0.0002013 | Direct |
| SMAD/FHA domain | 0.0003064 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.0003855 | Direct |
| RNA-binding domain, RBD | 0.0004119 | Direct |
| Growth factor receptor domain | 0.0004808 | Direct |
| Tropomyosin | 0.0005615 | Direct |
| Immunoglobulin | 0.0007898 | Direct |
| Class II aaRS and biotin synthetases | 0.0009023 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0.000942 | Direct |
| Cysteine-rich domain | 0.001457 | Inherited |
| Prefoldin | 0.001486 | Inherited |
| Hedgehog/intein (Hint) domain | 0.001665 | Inherited |
| Protein kinase-like (PK-like) | 0.003053 | Inherited |
| NAD(P)-linked oxidoreductase | 0.003219 | Inherited |
| Voltage-gated potassium channels | 0.003228 | Inherited |
| F1F0 ATP synthase subunit C | 0.00332 | Inherited |
| ARID-like | 0.00332 | Inherited |
| S15/NS1 RNA-binding domain | 0.00332 | Inherited |
| Frizzled cysteine-rich domain | 0.00332 | Inherited |
| Nucleic acid-binding proteins | 0.003527 | Inherited |
| Spectrin repeat | 0.004391 | Inherited |
| Zn-binding ribosomal proteins | 0.004609 | Inherited |
| cAMP-binding domain-like | 0.007763 | Inherited |
| Translation proteins SH3-like domain | 0.009521 | Inherited |
| EGF/Laminin | 0.01004 | Inherited |
| E2F-DP heterodimerization region | 0.01142 | Inherited |
| Cu,Zn superoxide dismutase-like | 0.01142 | Inherited |
| Integrin domains | 0.01142 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.01311 | Inherited |
| WD40 repeat-like | 0.01763 | Inherited |
| PLC-like phosphodiesterases | 0.01794 | Inherited |
| Fibronectin type III | 0.01908 | Inherited |
| Intermediate filament protein, coiled coil region | 0.02274 | Inherited |
| Lamin A/C globular tail domain | 0.02274 | Inherited |
| Arginase/deacetylase | 0.02839 | Inherited |
| SH3-domain | 0.03064 | Inherited |
| FYVE/PHD zinc finger | 0.03139 | Inherited |
| Periplasmic binding protein-like II | 0.04841 | Inherited |
| beta-beta-alpha zinc fingers | 0.04847 | Inherited |
| FKBP-like | 0.05182 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.05182 | Inherited |
| HD-domain/PDEase-like | 0.05182 | Inherited |
| DNA/RNA polymerases | 0.06367 | Inherited |
| Class II aaRS ABD-related | 0.06728 | Inherited |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.08391 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.08645 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.08645 | Inherited |
| PDZ domain-like | 0.09133 | Inherited |
| NTF2-like | 0.1032 | Inherited |
| Nucleotidylyl transferase | 0.1048 | Inherited |
| Thiamin diphosphate-binding fold (THDP-binding) | 0.1112 | Inherited |
| Myosin rod fragments | 0.1112 | Inherited |
| L30e-like | 0.1112 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1348 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 0.1703 | Inherited |
| EF-hand | 0.202 | Inherited |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.2099 | Inherited |
| Acyl-CoA dehydrogenase NM domain-like | 0.2099 | Inherited |
| Chromo domain-like | 0.2164 | Inherited |
| PLP-dependent transferases | 0.3029 | Inherited |
| NAD kinase/diacylglycerol kinase-like | 0.3829 | Inherited |
| Ubiquitin-like | 0.3896 | Inherited |
| LDL receptor-like module | 0.4137 | Inherited |
| Ankyrin repeat | 0.4982 | Inherited |
| FAD/NAD(P)-binding domain | 0.6845 | Inherited |
| BPTI-like | 0.7446 | Inherited |
| Saposin | 0.8202 | Inherited |
| C-type lectin-like | 1 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Laminin-type module | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| HSP20 | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
| Mammalian PLC | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0.00000000001627 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0.00000000002644 | DIRECT |
| Actin/HSP70 | 0.000000003485 | DIRECT |
| Homeodomain | 0.00000002768 | DIRECT |
| Nucleosome core histones | 0.00000004306 | DIRECT |
| Insulin-like | 0.0000002402 | DIRECT |
| Proteasome subunits | 0.0000002549 | DIRECT |
| Adenylyl and guanylyl cyclase catalytic domain | 0.0000003116 | DIRECT |
| L-arabinose binding protein-like | 0.000000523 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0.000008505 | DIRECT |
| Bromodomain | 0.00003878 | DIRECT |
| Band 7/SPFH domain | 0.00007323 | DIRECT |
| PLC-like (P variant) | 0.0001766 | DIRECT |
| SMAD domain | 0.0002242 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.0002242 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.0002297 | DIRECT |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.0002758 | DIRECT |
| SNF-like | 0.0003552 | DIRECT |
| Tubulin, C-terminal domain | 0.0004103 | DIRECT |
| PHD domain | 0.0004557 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0.0004851 | DIRECT |
| G proteins | 0.0005705 | DIRECT |
| PDZ domain | 0.0006707 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0.0006822 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0.0006822 | DIRECT |
| Tubulin, GTPase domain | 0.0009715 | DIRECT |
| Synaptotagmin-like (S variant) | 0.0009715 | DIRECT |
| Nicotinic receptor ligand binding domain-like | 0.0009753 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.001012 | INHERITED FROM: organism behavior variant || avoids bacterial lawn || feeding behavior variant |
| Tetratricopeptide repeat (TPR) | 0.001315 | INHERITED FROM: movement variant |
| Group II chaperonin (CCT, TRIC), apical domain | 0.001354 | INHERITED FROM: avoids bacterial lawn |
| Tandem AAA-ATPase domain | 0.001542 | INHERITED FROM: light response variant || organism UV response variant |
| Tropomyosin | 0.00184 | INHERITED FROM: sluggish || locomotion variant || locomotion reduced |
| Canonical RBD | 0.001934 | INHERITED FROM: locomotion variant || unfertilized oocytes laid |
| PDEase | 0.002063 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant |
| RecA protein-like (ATPase-domain) | 0.002063 | INHERITED FROM: avoids bacterial lawn |
| Growth factor receptor domain | 0.002255 | INHERITED FROM: quiescence variant |
| Spectrin repeat | 0.004612 | INHERITED FROM: movement variant || locomotion variant |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0.004612 | INHERITED FROM: movement variant || locomotion variant |
| Ubiquitin activating enzymes (UBA) | 0.006175 | INHERITED FROM: movement variant || locomotion variant |
| ARID domain | 0.006175 | INHERITED FROM: light response variant || organism UV hypersensitive || organism UV response variant |
| Smc hinge domain | 0.006175 | INHERITED FROM: movement variant || locomotion variant |
| Frizzled cysteine-rich domain | 0.006175 | INHERITED FROM: organism region behavior variant || body behavior variant || body muscle dystrophy || organism segment behavior variant |
| F1F0 ATP synthase subunit C | 0.006175 | INHERITED FROM: avoids bacterial lawn |
| I set domains | 0.008734 | INHERITED FROM: body posture variant || movement variant || forward locomotion decreased || path curvature increased || locomotion reduced || pausing increased |
| Clathrin coat assembly domain | 0.009703 | INHERITED FROM: movement variant || locomotion variant |
| Aldo-keto reductases (NADP) | 0.01054 | INHERITED FROM: defecation cycle variant || defecation variant |
| cAMP-binding domain | 0.01124 | INHERITED FROM: thermosensory behavior variant || odorant chemosensory response variant || frequency of body bend variant || egg laying defective || body posture wavelength variant || backward point velocity variant || odorant negative chemotaxis defective || male mating variant || chemosensory behavior variant || head bend angle variant || male mating defective || benzaldehyde chemotaxis defective || odorant positive chemotaxis variant || coiling variant || positive chemotaxis variant || positive chemotaxis defective || turning frequency variant || butanone chemotaxis variant || forward point velocity variant || sodium chloride chemotaxis defective || chemotaxis variant || thermotaxis variant || odorant positive chemotaxis defective || coiling frequency variant || directionality variant || roller || nose movement variant || bloated || body posture amplitude variant || path curvature variant || sodium chloride chemotaxis variant || turning variant || benzaldehyde chemotaxis variant || head movement variant || amplitude of sinusoidal movement variant |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.0132 | INHERITED FROM: thermosensory behavior variant || nose touch variant || eating variant || odorant positive chemotaxis variant || thermotaxis variant |
| H-NOX domain | 0.01835 | INHERITED FROM: eating variant || pharyngeal pumping rate variant || feeding behavior variant || induced pharyngeal pumping variant |
| Anticodon-binding domain | 0.01835 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| Cu,Zn superoxide dismutase-like | 0.01835 | INHERITED FROM: defecation cycle variant || defecation cycle variable length || defecation variant |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0.01835 | INHERITED FROM: defecation variant |
| Cell cycle transcription factor e2f-dp | 0.01835 | INHERITED FROM: backward locomotion variant || locomotor coordination variant || reversal variant || directionality variant |
| LIM domain | 0.02588 | INHERITED FROM: eating variant |
| Histone deacetylase, HDAC | 0.02669 | INHERITED FROM: light response variant || organism UV hypersensitive || organism UV response variant |
| Extended AAA-ATPase domain | 0.02852 | INHERITED FROM: feeding behavior variant |
| WD40-repeat | 0.03049 | INHERITED FROM: osmotic avoidance variant |
| Rhodopsin-like | 0.03647 | INHERITED FROM: egg laying phases variant || body bend variant || backward locomotion variant || egg laying variant || sinusoidal movement variant || body posture variant || serotonin induced pumping variant || fewer egg laying events during active || active phase variant || head bend angle variant || movement variant || eating variant || localized movement variant || velocity of movement variant || foraging behavior variant || satiety behavior variant || amplitude of sinusoidal movement decreased || pausing variant || turning frequency variant || forward locomotion variant || locomotor coordination variant || egg laying response to drug variant || coiling frequency variant || tail bend angle variant || directionality variant || nose movement variant || induced pharyngeal pumping variant || head movement variant || aqueous adaptation defective |
| Phosphate binding protein-like | 0.04342 | INHERITED FROM: thermosensory behavior variant || aqueous positive chemotaxis defective || chemosensory behavior variant || eating variant || positive chemotaxis defective || sodium chloride chemotaxis defective || chemotaxis variant || thermotaxis variant || pharyngeal pumping reduced || pharyngeal pumping rate variant || aqueous positive chemotaxis variant || sodium chloride chemotaxis variant || chemosensory response variant |
| Intermediate filament protein, coiled coil region | 0.04946 | INHERITED FROM: paralyzed |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.05138 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| Protein kinases, catalytic subunit | 0.05204 | INHERITED FROM: postembryonic behavior variant || organism region behavior variant || dauer nictation behavior variant || chemosensory behavior variant || egg laying response to food variant || velocity of movement increased || body muscle dystrophy || positive chemotaxis variant || alkaline pH chemotaxis variant || mechanosensation variant || dauer behavior variant || octanol chemotaxis defective || organism segment behavior variant |
| Pyridoxal-dependent decarboxylase | 0.05552 | INHERITED FROM: roaming increased || body posture wavelength variant || backward point velocity variant || body bend variant || backward locomotion variant || egg laying variant || sinusoidal movement variant || body posture variant || path curvature decreased || forward point velocity increased || localized movement variant || foraging behavior variant || turning frequency variant || forward locomotion variant || forward locomotion increased || forward point velocity variant || locomotor coordination variant || reversal variant || egg laying response to drug variant || body posture amplitude increased || tail bend angle variant || directionality variant || body posture amplitude variant || backward point velocity increased || activity level variant || head movement variant || amplitude of sinusoidal movement variant |
| Lamin A/C globular tail domain | 0.05552 | INHERITED FROM: paralyzed |
| Transforming growth factor (TGF)-beta | 0.06264 | INHERITED FROM: egg laying defective || egg laying variant |
| L30e/L7ae ribosomal proteins | 0.06264 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| DEP domain | 0.06264 | INHERITED FROM: organism region behavior variant || body behavior variant || body muscle dystrophy || organism segment behavior variant |
| Fibronectin type III | 0.09075 | INHERITED FROM: body posture variant || forward locomotion decreased || path curvature increased || locomotion reduced |
| FKBP immunophilin/proline isomerase | 0.0969 | INHERITED FROM: postembryonic behavior variant || developmental behavior variant || dauer behavior variant |
| Voltage-gated potassium channels | 0.1258 | INHERITED FROM: egg laying defective || backward point velocity variant || body bend variant || body posture variant || head bend angle variant || eating variant || localized movement variant || plate tap habituation variant || turning frequency variant || forward locomotion variant || expulsion defective || expulsion variant || habituation variant || forward point velocity variant || locomotor coordination variant || coiling frequency variant || roller || nose movement variant || flaccid || head movement variant |
| Lipovitellin-phosvitin complex, superhelical domain | 0.1314 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.1314 | INHERITED FROM: avoids bacterial lawn || feeding behavior variant |
| SH3-domain | 0.1601 | INHERITED FROM: ovulation variant |
| Motor proteins | 0.1713 | INHERITED FROM: sexually dimorphic mechanosensation variant || post hermaphrodite contact variant || male response to hermaphrodite variant || vulva location variant |
| Myosin rod fragments | 0.1812 | INHERITED FROM: sluggish |
| Regulator of G-protein signaling, RGS | 0.2182 | INHERITED FROM: negative chemotaxis variant || chemotaxis variant || mechanosensation variant |
| EGF-type module | 0.2392 | INHERITED FROM: activity level variant |
| Chromo domain | 0.2858 | INHERITED FROM: light response variant || organism UV hypersensitive || organism UV response variant |
| LDL receptor-like module | 0.6258 | INHERITED FROM: paralyzed |
| Ankyrin repeat | 0.8522 | INHERITED FROM: body bend variant || odorant negative chemotaxis defective || body posture wavelength decreased || backward locomotion variant || sinusoidal movement variant || head bend angle variant || localized movement variant || turning frequency variant || forward locomotion variant || reversal variant || tail bend angle variant || octanol chemotaxis variant || nose movement variant || octanol chemotaxis defective || turning variant || tail movement variant || head movement variant |
| Integrin A (or I) domain | 0.8929 | INHERITED FROM: paralyzed |
| Nuclear receptor | 1 | INHERITED FROM: solitary feeding increased |
| Acetylcholinesterase-like | 1 | INHERITED FROM: swimming variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: solitary feeding increased |
| C-type lectin domain | 1 | INHERITED FROM: male mating variant || sexually dimorphic behavior variant || male mating defective || copulation variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Laminin-type module | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| HSP20 | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Phoshatidylinositol transfer protein, PITP | 0 | Direct |
| Mammalian PLC | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Troponin I | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0.00000000001627 | Direct |
| Transducin (alpha subunit), insertion domain | 0.00000000002644 | Direct |
| Actin/HSP70 | 0.000000003485 | Direct |
| Homeodomain | 0.00000002768 | Direct |
| Nucleosome core histones | 0.00000004306 | Direct |
| Insulin-like | 0.0000002402 | Direct |
| Proteasome subunits | 0.0000002549 | Direct |
| Adenylyl and guanylyl cyclase catalytic domain | 0.0000003116 | Direct |
| L-arabinose binding protein-like | 0.000000523 | Direct |
| Pleckstrin-homology domain (PH domain) | 0.000008505 | Direct |
| Bromodomain | 0.00003878 | Direct |
| Band 7/SPFH domain | 0.00007323 | Direct |
| PLC-like (P variant) | 0.0001766 | Direct |
| SMAD domain | 0.0002242 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.0002242 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.0002297 | Direct |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.0002758 | Direct |
| SNF-like | 0.0003552 | Direct |
| Tubulin, C-terminal domain | 0.0004103 | Direct |
| PHD domain | 0.0004557 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0.0004851 | Direct |
| G proteins | 0.0005705 | Direct |
| PDZ domain | 0.0006707 | Direct |
| acyl-CoA oxidase C-terminal domains | 0.0006822 | Direct |
| acyl-CoA oxidase N-terminal domains | 0.0006822 | Direct |
| Tubulin, GTPase domain | 0.0009715 | Direct |
| Synaptotagmin-like (S variant) | 0.0009715 | Direct |
| Nicotinic receptor ligand binding domain-like | 0.0009753 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.001012 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.001315 | Inherited |
| Group II chaperonin (CCT, TRIC), apical domain | 0.001354 | Inherited |
| Tandem AAA-ATPase domain | 0.001542 | Inherited |
| Tropomyosin | 0.00184 | Inherited |
| Canonical RBD | 0.001934 | Inherited |
| PDEase | 0.002063 | Inherited |
| RecA protein-like (ATPase-domain) | 0.002063 | Inherited |
| Growth factor receptor domain | 0.002255 | Inherited |
| Spectrin repeat | 0.004612 | Inherited |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0.004612 | Inherited |
| Ubiquitin activating enzymes (UBA) | 0.006175 | Inherited |
| ARID domain | 0.006175 | Inherited |
| Smc hinge domain | 0.006175 | Inherited |
| Frizzled cysteine-rich domain | 0.006175 | Inherited |
| F1F0 ATP synthase subunit C | 0.006175 | Inherited |
| I set domains | 0.008734 | Inherited |
| Clathrin coat assembly domain | 0.009703 | Inherited |
| Aldo-keto reductases (NADP) | 0.01054 | Inherited |
| cAMP-binding domain | 0.01124 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.0132 | Inherited |
| H-NOX domain | 0.01835 | Inherited |
| Anticodon-binding domain | 0.01835 | Inherited |
| Cu,Zn superoxide dismutase-like | 0.01835 | Inherited |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0.01835 | Inherited |
| Cell cycle transcription factor e2f-dp | 0.01835 | Inherited |
| LIM domain | 0.02588 | Inherited |
| Histone deacetylase, HDAC | 0.02669 | Inherited |
| Extended AAA-ATPase domain | 0.02852 | Inherited |
| WD40-repeat | 0.03049 | Inherited |
| Rhodopsin-like | 0.03647 | Inherited |
| Phosphate binding protein-like | 0.04342 | Inherited |
| Intermediate filament protein, coiled coil region | 0.04946 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.05138 | Inherited |
| Protein kinases, catalytic subunit | 0.05204 | Inherited |
| Pyridoxal-dependent decarboxylase | 0.05552 | Inherited |
| Lamin A/C globular tail domain | 0.05552 | Inherited |
| Transforming growth factor (TGF)-beta | 0.06264 | Inherited |
| L30e/L7ae ribosomal proteins | 0.06264 | Inherited |
| DEP domain | 0.06264 | Inherited |
| Fibronectin type III | 0.09075 | Inherited |
| FKBP immunophilin/proline isomerase | 0.0969 | Inherited |
| Voltage-gated potassium channels | 0.1258 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.1314 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.1314 | Inherited |
| SH3-domain | 0.1601 | Inherited |
| Motor proteins | 0.1713 | Inherited |
| Myosin rod fragments | 0.1812 | Inherited |
| Regulator of G-protein signaling, RGS | 0.2182 | Inherited |
| EGF-type module | 0.2392 | Inherited |
| Chromo domain | 0.2858 | Inherited |
| LDL receptor-like module | 0.6258 | Inherited |
| Ankyrin repeat | 0.8522 | Inherited |
| Integrin A (or I) domain | 0.8929 | Inherited |
| Nuclear receptor | 1 | Inherited |
| Acetylcholinesterase-like | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| C-type lectin domain | 1 | Inherited |
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0.00000000000009442 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0.0000000000005283 | DIRECT |
| HSP20-like chaperones | 0.000000000009038 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0.00000000003932 | DIRECT |
| Histone-fold | 0.0000000001523 | DIRECT |
| Periplasmic binding protein-like I | 0.000000001472 | DIRECT |
| Nucleotide cyclase | 0.000000004288 | DIRECT |
| Homeodomain-like | 0.000000006914 | DIRECT |
| Insulin-like | 0.000000007745 | DIRECT |
| ARM repeat | 0.0000003217 | DIRECT |
| TPR-like | 0.0000008391 | DIRECT |
| Band 7/SPFH domain | 0.000002995 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.000004744 | DIRECT |
| Bromodomain | 0.000004747 | DIRECT |
| "Winged helix" DNA-binding domain | 0.000009399 | DIRECT |
| Actin-like ATPase domain | 0.00001298 | DIRECT |
| GroEL equatorial domain-like | 0.00001614 | DIRECT |
| GroEL-intermediate domain like | 0.00001614 | DIRECT |
| Sm-like ribonucleoproteins | 0.00002001 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.00002201 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0.0000243 | DIRECT |
| Tubulin C-terminal domain-like | 0.00005802 | DIRECT |
| Nicotinic receptor ligand binding domain-like | 0.0001062 | DIRECT |
| GroEL apical domain-like | 0.0001166 | DIRECT |
| SNF-like | 0.0001647 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0.0001647 | DIRECT |
| PH domain-like | 0.0001653 | DIRECT |
| SMAD/FHA domain | 0.0002524 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.0003179 | DIRECT |
| RNA-binding domain, RBD | 0.0003401 | DIRECT |
| Growth factor receptor domain | 0.0003978 | DIRECT |
| Tropomyosin | 0.0004651 | DIRECT |
| Immunoglobulin | 0.0006567 | DIRECT |
| Class II aaRS and biotin synthetases | 0.0007507 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0.0007838 | DIRECT |
| Cysteine-rich domain | 0.001217 | INHERITED FROM: thermosensory behavior variant || odorant chemosensory response variant || eating variant || positive chemotaxis variant || odorant positive chemotaxis variant || thermotaxis variant |
| Prefoldin | 0.001241 | INHERITED FROM: locomotion variant |
| Hedgehog/intein (Hint) domain | 0.001392 | INHERITED FROM: locomotion variant || movement variant |
| Protein kinase-like (PK-like) | 0.002577 | INHERITED FROM: velocity of movement increased || dauer behavior variant || aqueous chemosensory response variant || dauer nictation behavior variant || alkaline pH chemotaxis variant || chemosensory behavior variant || body muscle dystrophy || positive chemotaxis variant || late stage egg laid || developmental behavior variant || organism segment behavior variant || egg laying response to food variant || octanol chemotaxis defective || mechanosensation variant || organism region behavior variant || postembryonic behavior variant |
| NAD(P)-linked oxidoreductase | 0.00272 | INHERITED FROM: defecation variant || defecation cycle variant |
| Voltage-gated potassium channels | 0.002728 | INHERITED FROM: bloated || plate tap habituation variant || turning frequency variant || head bend angle variant || flaccid || body posture variant || positive chemotaxis defective || forward locomotion variant || expulsion variant || localized movement variant || backward point velocity variant || spicule insertion defective || expulsion defective || locomotor coordination variant || tail bend angle variant || hyperactive egg laying || activity level variant || forward point velocity variant || head movement variant || backward locomotion variant || eating variant || roller || coiling frequency variant || bag of worms || mechanosensation variant || egg laying defective || habituation variant || body bend variant |
| F1F0 ATP synthase subunit C | 0.002806 | INHERITED FROM: avoids bacterial lawn |
| ARID-like | 0.002806 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
| Frizzled cysteine-rich domain | 0.002806 | INHERITED FROM: body muscle dystrophy || organism segment behavior variant || body behavior variant || organism region behavior variant |
| S15/NS1 RNA-binding domain | 0.002806 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
| Nucleic acid-binding proteins | 0.002984 | INHERITED FROM: avoids bacterial lawn |
| Spectrin repeat | 0.003723 | INHERITED FROM: locomotion variant || movement variant |
| Zn-binding ribosomal proteins | 0.003912 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
| cAMP-binding domain-like | 0.006637 | INHERITED FROM: male mating variant || benzaldehyde chemotaxis defective || bloated || turning frequency variant || head bend angle variant || amplitude of sinusoidal movement variant || directionality variant || positive chemotaxis defective || thermosensory behavior variant || coiling variant || male mating defective || frequency of body bend variant || body posture wavelength variant || backward point velocity variant || butanone chemotaxis variant || odorant chemosensory response variant || chemosensory behavior variant || benzaldehyde chemotaxis variant || sodium chloride chemotaxis variant || forward point velocity variant || head movement variant || turning variant || positive chemotaxis variant || roller || odorant positive chemotaxis defective || coiling frequency variant || odorant positive chemotaxis variant || sodium chloride chemotaxis defective || nose movement variant || path curvature variant || chemotaxis variant || odorant negative chemotaxis defective || egg laying defective || body bend variant || sinusoidal movement variant || body posture amplitude variant || thermotaxis variant |
| Translation proteins SH3-like domain | 0.008179 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
| EGF/Laminin | 0.008633 | INHERITED FROM: locomotion variant || octanol chemotaxis variant || movement variant || octanol chemotaxis defective || odorant negative chemotaxis defective |
| Integrin domains | 0.009843 | INHERITED FROM: egg laying variant |
| E2F-DP heterodimerization region | 0.009843 | INHERITED FROM: directionality variant || locomotor coordination variant || backward locomotion variant || reversal variant |
| Cu,Zn superoxide dismutase-like | 0.009843 | INHERITED FROM: defecation variant || defecation cycle variant || defecation cycle variable length |
| PYP-like sensor domain (PAS domain) | 0.01133 | INHERITED FROM: egg laying variant || egg laying defective |
| WD40 repeat-like | 0.01532 | INHERITED FROM: osmotic avoidance variant |
| PLC-like phosphodiesterases | 0.01558 | INHERITED FROM: male mating variant || defecation variant || male mating defective || copulation variant || defecation contraction variant || spicule insertion defective || posterior body wall contraction defecation cycle variant || sexually dimorphic behavior variant || ovulation variant |
| Fibronectin type III | 0.01658 | INHERITED FROM: locomotion reduced || body posture variant || reversal variant || forward locomotion decreased || path curvature increased |
| Lamin A/C globular tail domain | 0.01984 | INHERITED FROM: paralyzed |
| Intermediate filament protein, coiled coil region | 0.01984 | INHERITED FROM: paralyzed |
| Arginase/deacetylase | 0.0249 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
| SH3-domain | 0.02691 | INHERITED FROM: ovulation variant |
| FYVE/PHD zinc finger | 0.02759 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
| Periplasmic binding protein-like II | 0.04286 | INHERITED FROM: aqueous positive chemotaxis defective || positive chemotaxis defective || thermosensory behavior variant || pharyngeal pumping rate variant || chemosensory behavior variant || sodium chloride chemotaxis variant || eating variant || sodium chloride chemotaxis defective || pharyngeal pumping reduced || aqueous positive chemotaxis variant || chemotaxis variant || chemosensory response variant || thermotaxis variant |
| beta-beta-alpha zinc fingers | 0.04291 | INHERITED FROM: egg laying serotonin resistant || egg laying imipramine resistant |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.04598 | INHERITED FROM: induced pharyngeal pumping variant || pharyngeal pumping rate variant || eating variant |
| FKBP-like | 0.04598 | INHERITED FROM: dauer behavior variant || developmental behavior variant || postembryonic behavior variant |
| HD-domain/PDEase-like | 0.04598 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant |
| DNA/RNA polymerases | 0.05675 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
| Class II aaRS ABD-related | 0.06006 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.0754 | INHERITED FROM: avoids bacterial lawn |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0777 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
| Lipovitellin-phosvitin complex, superhelical domain | 0.0777 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
| PDZ domain-like | 0.08224 | INHERITED FROM: body muscle dystrophy || ovulation variant || organism segment behavior variant || body behavior variant || organism region behavior variant |
| NTF2-like | 0.09325 | INHERITED FROM: male mating variant || male mating defective || copulation variant || sexually dimorphic behavior variant |
| Nucleotidylyl transferase | 0.09475 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
| Thiamin diphosphate-binding fold (THDP-binding) | 0.1007 | INHERITED FROM: avoids bacterial lawn |
| L30e-like | 0.1007 | INHERITED FROM: avoids bacterial lawn |
| Myosin rod fragments | 0.1007 | INHERITED FROM: sluggish |
| Regulator of G-protein signaling, RGS | 0.1227 | INHERITED FROM: chemotaxis variant || mechanosensation variant || negative chemotaxis variant |
| Glutathione synthetase ATP-binding domain-like | 0.1561 | INHERITED FROM: male mating variant || copulation variant || chemosensory behavior variant || sexually dimorphic behavior variant || osmotic avoidance variant || male mating efficiency reduced || chemotaxis variant || negative chemotaxis variant |
| EF-hand | 0.1861 | INHERITED FROM: defecation contraction variant || ovulation variant |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.1937 | INHERITED FROM: defecation variant || defecation cycle variant |
| Acyl-CoA dehydrogenase NM domain-like | 0.1937 | INHERITED FROM: defecation variant || defecation cycle variant |
| Chromo domain-like | 0.1999 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
| PLP-dependent transferases | 0.2837 | INHERITED FROM: forward point velocity increased || backward point velocity increased || defecation contraction variant || expulsion variant || forward locomotion increased || path curvature decreased || body posture amplitude increased |
| NAD kinase/diacylglycerol kinase-like | 0.3624 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant |
| Ubiquitin-like | 0.3691 | INHERITED FROM: body muscle dystrophy || organism segment behavior variant || body behavior variant || organism region behavior variant |
| LDL receptor-like module | 0.393 | INHERITED FROM: paralyzed |
| Ankyrin repeat | 0.4765 | INHERITED FROM: turning frequency variant || head bend angle variant || body posture variant || forward locomotion variant || localized movement variant || tail bend angle variant || head movement variant || backward locomotion variant || turning variant || tail movement variant || octanol chemotaxis variant || nose movement variant || octanol chemotaxis defective || reversal variant || body posture wavelength decreased || chemotaxis variant || odorant negative chemotaxis defective || chemosensory response variant || body bend variant || sinusoidal movement variant |
| FAD/NAD(P)-binding domain | 0.6633 | INHERITED FROM: fewer eggs laid |
| BPTI-like | 0.7247 | INHERITED FROM: male mating defective |
| Saposin | 0.8023 | INHERITED FROM: fewer eggs laid |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: solitary feeding increased |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | INHERITED FROM: solitary feeding increased |
| C-type lectin-like | 1 | INHERITED FROM: male mating variant || male mating defective || copulation variant || sexually dimorphic behavior variant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: induced pharyngeal pumping variant || serotonin induced pumping variant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0.00000000000009442 | Direct |
| Transducin (alpha subunit), insertion domain | 0.0000000000005283 | Direct |
| HSP20-like chaperones | 0.000000000009038 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0.00000000003932 | Direct |
| Histone-fold | 0.0000000001523 | Direct |
| Periplasmic binding protein-like I | 0.000000001472 | Direct |
| Nucleotide cyclase | 0.000000004288 | Direct |
| Homeodomain-like | 0.000000006914 | Direct |
| Insulin-like | 0.000000007745 | Direct |
| ARM repeat | 0.0000003217 | Direct |
| TPR-like | 0.0000008391 | Direct |
| Band 7/SPFH domain | 0.000002995 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.000004744 | Direct |
| Bromodomain | 0.000004747 | Direct |
| "Winged helix" DNA-binding domain | 0.000009399 | Direct |
| Actin-like ATPase domain | 0.00001298 | Direct |
| GroEL equatorial domain-like | 0.00001614 | Direct |
| GroEL-intermediate domain like | 0.00001614 | Direct |
| Sm-like ribonucleoproteins | 0.00002001 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.00002201 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0.0000243 | Direct |
| Tubulin C-terminal domain-like | 0.00005802 | Direct |
| Nicotinic receptor ligand binding domain-like | 0.0001062 | Direct |
| GroEL apical domain-like | 0.0001166 | Direct |
| SNF-like | 0.0001647 | Direct |
| Tubulin nucleotide-binding domain-like | 0.0001647 | Direct |
| PH domain-like | 0.0001653 | Direct |
| SMAD/FHA domain | 0.0002524 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.0003179 | Direct |
| RNA-binding domain, RBD | 0.0003401 | Direct |
| Growth factor receptor domain | 0.0003978 | Direct |
| Tropomyosin | 0.0004651 | Direct |
| Immunoglobulin | 0.0006567 | Direct |
| Class II aaRS and biotin synthetases | 0.0007507 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0.0007838 | Direct |
| Cysteine-rich domain | 0.001217 | Inherited |
| Prefoldin | 0.001241 | Inherited |
| Hedgehog/intein (Hint) domain | 0.001392 | Inherited |
| Protein kinase-like (PK-like) | 0.002577 | Inherited |
| NAD(P)-linked oxidoreductase | 0.00272 | Inherited |
| Voltage-gated potassium channels | 0.002728 | Inherited |
| F1F0 ATP synthase subunit C | 0.002806 | Inherited |
| ARID-like | 0.002806 | Inherited |
| Frizzled cysteine-rich domain | 0.002806 | Inherited |
| S15/NS1 RNA-binding domain | 0.002806 | Inherited |
| Nucleic acid-binding proteins | 0.002984 | Inherited |
| Spectrin repeat | 0.003723 | Inherited |
| Zn-binding ribosomal proteins | 0.003912 | Inherited |
| cAMP-binding domain-like | 0.006637 | Inherited |
| Translation proteins SH3-like domain | 0.008179 | Inherited |
| EGF/Laminin | 0.008633 | Inherited |
| Integrin domains | 0.009843 | Inherited |
| E2F-DP heterodimerization region | 0.009843 | Inherited |
| Cu,Zn superoxide dismutase-like | 0.009843 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.01133 | Inherited |
| WD40 repeat-like | 0.01532 | Inherited |
| PLC-like phosphodiesterases | 0.01558 | Inherited |
| Fibronectin type III | 0.01658 | Inherited |
| Lamin A/C globular tail domain | 0.01984 | Inherited |
| Intermediate filament protein, coiled coil region | 0.01984 | Inherited |
| Arginase/deacetylase | 0.0249 | Inherited |
| SH3-domain | 0.02691 | Inherited |
| FYVE/PHD zinc finger | 0.02759 | Inherited |
| Periplasmic binding protein-like II | 0.04286 | Inherited |
| beta-beta-alpha zinc fingers | 0.04291 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.04598 | Inherited |
| FKBP-like | 0.04598 | Inherited |
| HD-domain/PDEase-like | 0.04598 | Inherited |
| DNA/RNA polymerases | 0.05675 | Inherited |
| Class II aaRS ABD-related | 0.06006 | Inherited |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.0754 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0777 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.0777 | Inherited |
| PDZ domain-like | 0.08224 | Inherited |
| NTF2-like | 0.09325 | Inherited |
| Nucleotidylyl transferase | 0.09475 | Inherited |
| Thiamin diphosphate-binding fold (THDP-binding) | 0.1007 | Inherited |
| L30e-like | 0.1007 | Inherited |
| Myosin rod fragments | 0.1007 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1227 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 0.1561 | Inherited |
| EF-hand | 0.1861 | Inherited |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.1937 | Inherited |
| Acyl-CoA dehydrogenase NM domain-like | 0.1937 | Inherited |
| Chromo domain-like | 0.1999 | Inherited |
| PLP-dependent transferases | 0.2837 | Inherited |
| NAD kinase/diacylglycerol kinase-like | 0.3624 | Inherited |
| Ubiquitin-like | 0.3691 | Inherited |
| LDL receptor-like module | 0.393 | Inherited |
| Ankyrin repeat | 0.4765 | Inherited |
| FAD/NAD(P)-binding domain | 0.6633 | Inherited |
| BPTI-like | 0.7247 | Inherited |
| Saposin | 0.8023 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | Inherited |
| C-type lectin-like | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0000000000005283 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.0000002693 | DIRECT |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.000004744 | DIRECT |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.000005156 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000007586 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.00001614 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.00001614 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.0001647 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0.0002164 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.0002164 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.0002524 | DIRECT |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.000349 | DIRECT |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.0003565 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.001072 | INHERITED FROM: locomotion variant |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.001449 | INHERITED FROM: iodide chemotaxis defective || bromide chemotaxis defective || aqueous chemosensory response variant || alkaline pH chemotaxis variant || lithium chemotaxis defective || chemosensory behavior variant || AWC odorant chemotaxis variant || cation positive chemotaxis defective || AWC odorant chemotaxis defective || benzaldehyde chemotaxis variant || magnesium chemotaxis defective || positive chemotaxis variant || cation positive chemotaxis variant || iodide chemotaxis variant || anion positive chemotaxis variant || chemotaxis variant || anion positive chemotaxis defective || chemosensory response variant || bromide chemotaxis variant |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.002806 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0.002806 | INHERITED FROM: dauer behavior variant || developmental behavior variant || postembryonic behavior variant |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.003239 | INHERITED FROM: defecation variant || defecation contraction variant || expulsion variant |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.003239 | INHERITED FROM: eating variant |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0.003912 | INHERITED FROM: paralyzed || locomotion reduced |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0.004043 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.009516 | INHERITED FROM: turning frequency variant || head bend angle variant || locomotion reduced || amplitude of sinusoidal movement variant || body posture variant || backward point velocity variant || locomotor coordination variant || body posture amplitude decreased || tail bend angle variant || forward point velocity variant || head movement variant || backward locomotion variant || turning variant || tail movement variant || nose movement variant || movement variant || reversal variant || forward locomotion decreased || egg laying defective |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0.009843 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.009843 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.0249 | INHERITED FROM: turning frequency variant || head bend angle variant || amplitude of sinusoidal movement variant || backing decreased || directionality variant || body posture variant || coiling variant || frequency of body bend variant || forward locomotion variant || localized movement variant || backward point velocity variant || velocity of movement variant || tail bend angle variant || forward point velocity variant || head movement variant || backward locomotion variant || turning variant || coiling frequency variant || tail movement variant || nose movement variant || path curvature variant || reversal variant || pausing variant || coiling frequency increased || body bend variant || sinusoidal movement variant || body posture amplitude variant |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0.03049 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0.03525 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.03525 | INHERITED FROM: body bend variant || sinusoidal movement variant |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.0777 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0777 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.158 | INHERITED FROM: aqueous positive chemotaxis defective || positive chemotaxis defective || aqueous chemosensory response variant || odorant chemosensory response variant || positive chemotaxis variant || osmotic avoidance variant || aqueous positive chemotaxis variant || chemotaxis variant || mechanosensation variant || negative chemotaxis variant |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.1937 | INHERITED FROM: defecation variant || defecation cycle variant |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.2094 | INHERITED FROM: paralyzed |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0000000000005283 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.0000002693 | Direct |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.000004744 | Direct |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.000005156 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000007586 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.00001614 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.00001614 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.0001647 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0.0002164 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.0002164 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.0002524 | Direct |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.000349 | Direct |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.0003565 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.001072 | Inherited |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.001449 | Inherited |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.002806 | Inherited |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0.002806 | Inherited |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.003239 | Inherited |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.003239 | Inherited |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0.003912 | Inherited |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0.004043 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.009516 | Inherited |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0.009843 | Inherited |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.009843 | Inherited |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.0249 | Inherited |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0.03049 | Inherited |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0.03525 | Inherited |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.03525 | Inherited |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.0777 | Inherited |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0777 | Inherited |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.158 | Inherited |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.1937 | Inherited |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.2094 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.00001614 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.0002164 | DIRECT |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.0004556 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.004043 | INHERITED FROM: locomotion variant || locomotion reduced || movement variant |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.009829 | INHERITED FROM: locomotion reduced || body posture variant || movement variant || egg laying defective |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.009843 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.009843 | INHERITED FROM: organism UV hypersensitive || organism UV response variant || light response variant |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.01098 | INHERITED FROM: turning frequency variant || head bend angle variant || locomotion reduced || amplitude of sinusoidal movement variant || body posture variant || backward point velocity variant || body posture amplitude decreased || tail bend angle variant || forward point velocity variant || head movement variant || backward locomotion variant || turning variant || tail movement variant || nose movement variant || movement variant || reversal variant || body posture wavelength decreased || body bend variant |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.0754 | INHERITED FROM: paralyzed |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0777 | INHERITED FROM: feeding behavior variant || avoids bacterial lawn |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.00001614 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.0002164 | Direct |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.0004556 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.004043 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.009829 | Inherited |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.009843 | Inherited |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.009843 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.01098 | Inherited |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.0754 | Inherited |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0777 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
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