|
|
Worm Phenotype (WP): morphology variant
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Doublecortin (DC) | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| SMR domain-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Ricin B-like lectins | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| Tudor/PWWP/MBT | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Pseudouridine synthase | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| BPTI-like | 0 | DIRECT |
| Ganglioside M2 (gm2) activator | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Hairpin loop containing domain-like | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| alpha-helical ferredoxin | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Actin-crosslinking proteins | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
| Glutamine synthetase, N-terminal domain | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| SNF-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| Osmotin, thaumatin-like protein | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Concanavalin A-like lectins/glucanases | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| SpoIIaa-like | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| Tautomerase/MIF | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Cystine-knot cytokines | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| LDL receptor-like module | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| CalX-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Nucleic acid-binding proteins | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIc | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| Periplasmic binding protein-like I | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| UBA-like | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| ARM repeat | 0.01092 | INHERITED FROM: P granule localization defective || embryonic cell organization biogenesis variant || developmental morphology variant || vesicle organization variant || seam cell morphology variant || pigmentation variant || organ system morphology variant || vulva morphology variant || EMS anterior extension fails early emb || cell morphology variant || dye filling defect || amphid phasmid neuron morphology variant || microtubule organization biogenesis variant |
| MFS general substrate transporter | 0.02984 | INHERITED FROM: organism morphology variant |
| RNA-binding domain, RBD | 0.06234 | INHERITED FROM: P granule localization defective || egg morphology variant || oocytes disorganized || reproductive system morphology variant || developmental morphology variant || cuticle morphology variant || embryonic morphology variant || vulva morphology variant || cell morphology variant |
| L domain-like | 0.06403 | INHERITED FROM: myopodia present |
| Ankyrin repeat | 0.145 | INHERITED FROM: fat |
| P-loop containing nucleoside triphosphate hydrolases | 0.1965 | INHERITED FROM: embryonic cell organization biogenesis variant || actin organization biogenesis variant || embryonic cell morphology variant || vesicle organization variant || cell type morphology variant || endoplasmic reticulum morphology variant || body region morphology variant || organism segment morphology variant || gonad arm morphology variant || organ system morphology variant || cell cell contacts abnormal in four cell embryo || cell morphology variant || lumpy || axon morphology variant || excessive blebbing early emb || microtubule organization biogenesis variant |
| Immunoglobulin | 0.1979 | INHERITED FROM: neurite morphology variant || sperm morphology variant || synapse morphology variant || nervous system morphology variant || neuron morphology variant || sperm pseudopod variant || body wall muscle sarcomere morphology variant || mitochondria morphology variant || body region morphology variant || organism segment morphology variant || cell morphology variant || muscle system morphology variant || muscle cell morphology variant |
| EGF/Laminin | 0.2082 | INHERITED FROM: developmental morphology variant || clear || body wall muscle sarcomere morphology variant || axon trajectory variant || rectal morphology variant || muscle cell morphology variant || no rectum |
| FYVE/PHD zinc finger | 0.3116 | INHERITED FROM: tail morphology variant |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3439 | INHERITED FROM: body wall muscle sarcomere morphology variant || mitochondria morphology variant || endomitotic oocytes || mitochondria alignment variant || cell morphology variant || muscle system morphology variant || striated muscle morphology variant |
| Voltage-gated potassium channels | 0.3863 | INHERITED FROM: body wall muscle sarcomere morphology variant || mitochondria morphology variant || dumpy || short || muscle system morphology variant || striated muscle morphology variant || muscle cell morphology variant |
| TPR-like | 0.3863 | INHERITED FROM: ciliated neuron morphology variant || cilia morphology variant || embryonic cell organization biogenesis variant || mitotic spindle defective early emb || sensillum morphology variant || pronucleus centrosomes defective early emb || organ system morphology variant || sexually dimorphic morphology variant || cell morphology variant || dye filling defect || male morphology variant || spindle variant || microtubule organization biogenesis variant |
| Homeodomain-like | 0.3874 | INHERITED FROM: neuron positioning variant || nervous system morphology variant || body axis morphology variant || tail morphology variant || organism morphology variable || body region morphology variant || organism segment morphology variant || organ system morphology variant || sexually dimorphic morphology variant || male morphology variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3932 | INHERITED FROM: fat || body size variant || body region morphology variant || organism segment morphology variant || short |
| Ubiquitin-like | 0.45 | INHERITED FROM: cell morphology variant |
| HLH, helix-loop-helix DNA-binding domain | 0.4596 | INHERITED FROM: organ system morphology variant |
| Ribosomal protein S5 domain 2-like | 0.4711 | INHERITED FROM: nuclear appearance variant || germ cell compartment expansion variant |
| WD40 repeat-like | 0.4993 | INHERITED FROM: endosome morphology variant || embryonic cell organization biogenesis variant || vesicle organization variant || organ system morphology variant || vulva morphology variant || early endosome morphology variant || cell morphology variant || vesicle morphology variant || cytoplasmic morphology defective early emb |
| GTPase activation domain, GAP | 0.5566 | INHERITED FROM: neurite morphology variant || axon branching variant || nervous system morphology variant || neuron morphology variant || mitochondria alignment variant || organ system morphology variant || mitochondria spacing variant || cell morphology variant || axon morphology variant |
| Calponin-homology domain, CH-domain | 0.5693 | INHERITED FROM: actin organization biogenesis variant || mitochondria alignment variant || organ system morphology variant || cell morphology variant || muscle system morphology variant || body wall muscle myosin organization defective || striated muscle morphology variant |
| Nicotinic receptor ligand binding domain-like | 0.5795 | INHERITED FROM: fat || body size variant || body region morphology variant || organism segment morphology variant || short |
| EF-hand | 0.5795 | INHERITED FROM: annulae morphology variant || endomitotic oocytes |
| p53-like transcription factors | 0.5813 | INHERITED FROM: developmental morphology variant || alimentary system morphology variant || epithelial system morphology variant || epithelial morphology variant |
| Cyclin-like | 0.5813 | INHERITED FROM: pronuclear size defective early emb || embryonic cell organization biogenesis variant || multiple nuclei early emb || nuclear appearance number defective early emb || embryonic cell morphology variant || multiple cytoplasmic cavities early emb || pigmentation variant || organism pigmentation variant || nuclear morphology variation early emb || pronucleus centrosomes defective early emb || pronuclear morphology defective early emb || excess pronucleus early emb || excess maternal pronucleus early emb || cytoplasmic appearance variant || nucleus defective early emb |
| "Winged helix" DNA-binding domain | 0.5936 | INHERITED FROM: embryonic cell organization biogenesis variant || age associated fluorescence increased || reproductive system morphology variant || mitotic spindle defective early emb || organ system morphology variant || spindle rotation variant || vulva morphology variant || cell morphology variant || rachis absent || microtubule organization biogenesis variant |
| BAR/IMD domain-like | 0.5947 | INHERITED FROM: amphid phasmid sensillum morphology variant || dye filling defect |
| Lipocalins | 0.6087 | INHERITED FROM: age associated fluorescence increased || developmental pigmentation variant |
| SAM/Pointed domain | 0.6087 | INHERITED FROM: synapse morphology variant |
| NAD(P)-binding Rossmann-fold domains | 0.6904 | INHERITED FROM: vulval invagination variant L4 || fat associated bodies variant |
| Protein kinase-like (PK-like) | 0.7095 | INHERITED FROM: mitochondrial content variant || germ nuclei rachis || mitochondria alignment variant || myopodia present || rod like larval lethal || muscle cell morphology variant |
| dsRNA-binding domain-like | 0.7863 | INHERITED FROM: alae morphology variant || pericellular component morphology variant || cuticle morphology variant || germ cell morphology variant || cytoplasmic processing body variant |
| LuxS/MPP-like metallohydrolase | 0.8403 | INHERITED FROM: egg morphology variant || developmental morphology variant || embryonic morphology variant |
| Translation proteins SH3-like domain | 0.8403 | INHERITED FROM: rachis morphology variant || cell membrane organization biogenesis variant || gonad vesiculated || rachis narrow || pachytene region organization variant || cell type morphology variant || germ cell morphology variant || organ system morphology variant || oocyte number decreased || germ cell compartment expansion variant || cell component morphology variant |
| Cysteine proteinases | 0.8589 | INHERITED FROM: developmental pigmentation variant |
| (Phosphotyrosine protein) phosphatases II | 0.8894 | INHERITED FROM: mitochondria alignment variant || mitochondria spacing variant |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.9292 | INHERITED FROM: endosome morphology variant || gonad morphology variant || recycling endosome localization variant || rachis morphology variant || cell membrane organization biogenesis variant || reproductive system morphology variant || gonad vesiculated || rachis narrow || vesicle organization variant || cell type morphology variant || lysosome-related organelle morphology variant || germ cell morphology variant || germ cell compartment morphology variant || cell morphology variant || oocytes lack nucleus || vesicle morphology variant || cell component morphology variant || RAB-11 recycling endosome localization variant || recycling endosome morphology variant |
| Zn-binding ribosomal proteins | 0.9384 | INHERITED FROM: reproductive system morphology variant || body size variant || body morphology variant || body region morphology variant || germ cell morphology variant || organism segment morphology variant || body width variant || cytoplasmic processing body variant |
| Thioredoxin-like | 0.9607 | INHERITED FROM: pseudocoelom morphology variant |
| GST C-terminal domain-like | 0.9626 | INHERITED FROM: pseudocoelom morphology variant |
| Trimeric LpxA-like enzymes | 0.977 | INHERITED FROM: cell morphology variant |
| S15/NS1 RNA-binding domain | 0.977 | INHERITED FROM: gonad morphology variant || rachis morphology variant || rachis narrow || pachytene region organization variant || germ cell morphology variant || germ cell compartment morphology variant || oocyte morphology variant || germ cell compartment expansion variant |
| POZ domain | 0.9879 | INHERITED FROM: embryonic cell organization biogenesis variant || cytoskeleton organization biogenesis variant || spindle position orientation defective early emb || cytoplasmic appearance defective early emb || spindle position defective early emb || spindle position variant || body axis morphology variant || mitotic spindle defective early emb || cytoplasmic dynamics defective early emb || posterior body morphology variant || spindle defective early emb || excessive blebbing early emb || spindle variant || cytoplasmic appearance variant || microtubule organization biogenesis variant |
| Class II aaRS and biotin synthetases | 0.9927 | INHERITED FROM: germline nuclear positioning variant || germ cell morphology variant || diakinesis region organization variant || organ system morphology variant || cytoplasmic processing body variant || cell morphology variant || germ cell compartment anucleate || germ cell compartment expansion variant || cell component morphology variant |
| GINS helical bundle-like | 0.9954 | INHERITED FROM: hermaphrodite reproductive system morphology variant || reproductive system morphology variant || protruding vulva || vulva morphology variant |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | INHERITED FROM: gonad morphology variant || rachis morphology variant || germline nuclear positioning variant || pachytene region organization variant || germ cell compartment morphology variant || oocyte number decreased || oocyte morphology variant || germ cell compartment expansion variant || nuclei enlarged |
| C-type lectin-like | 1 | INHERITED FROM: tail swelling || rays displaced |
| PAZ domain | 1 | INHERITED FROM: alae morphology variant || breaks in alae |
| SH2 domain | 1 | INHERITED FROM: body wall muscle sarcomere morphology variant || mitochondria morphology variant || mitochondria alignment variant || mitochondria spacing variant || cell component localization variant || muscle system morphology variant || striated muscle morphology variant || muscle cell morphology variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: protruding vulva || sexually dimorphic morphology variant || male morphology variant |
| Nucleotidylyl transferase | 1 | INHERITED FROM: nuclei enlarged |
| Histone-fold | 1 | INHERITED FROM: endosome morphology variant || gonad small || recycling endosome localization variant || intestinal degeneration || protruding vulva || vesicle organization variant || lysosome-related organelle morphology variant || thin || cell component localization variant || cell morphology variant || vesicle morphology variant || RAB-11 recycling endosome localization variant || endosome localization variant || recycling endosome morphology variant |
| Insulin-like | 1 | INHERITED FROM: body length variant || body morphology variant || body region morphology variant || small || organism segment morphology variant || body width variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Doublecortin (DC) | 0 | Direct |
| Ras GEF | 0 | Direct |
| GAT-like domain | 0 | Direct |
| SMR domain-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Ricin B-like lectins | 0 | Direct |
| PapD-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| FF domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| ARID-like | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| UBC-like | 0 | Direct |
| Annexin | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Aldolase | 0 | Direct |
| HCP-like | 0 | Direct |
| DEATH domain | 0 | Direct |
| ADC-like | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| PH domain-like | 0 | Direct |
| Tudor/PWWP/MBT | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Tim10-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Pseudouridine synthase | 0 | Direct |
| WWE domain | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| PX domain | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Pentein | 0 | Direct |
| TAZ domain | 0 | Direct |
| Elafin-like | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| BPTI-like | 0 | Direct |
| Ganglioside M2 (gm2) activator | 0 | Direct |
| ALDH-like | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| Tropomyosin | 0 | Direct |
| GroES-like | 0 | Direct |
| t-snare proteins | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Hairpin loop containing domain-like | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Lysozyme-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| Acid proteases | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Sema domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| MIR domain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Plexin repeat | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| WGR domain-like | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| alpha-helical ferredoxin | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Actin-crosslinking proteins | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Nudix | 0 | Direct |
| NHL repeat | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| LEM domain | 0 | Direct |
| WW domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Cupredoxins | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| PR-1-like | 0 | Direct |
| Multidrug resistance efflux transporter EmrE | 0 | Direct |
| Glutamine synthetase, N-terminal domain | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| SNARE-like | 0 | Direct |
| DNase I-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| SNF-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| CBD9-like | 0 | Direct |
| Kringle-like | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| PUA domain-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| SET domain | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| SIS domain | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| Osmotin, thaumatin-like protein | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| ACP-like | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| KA1-like | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| MIT domain | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Polo-box domain | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Concanavalin A-like lectins/glucanases | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| GYF domain | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| LysM domain | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| BEACH domain | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| SpoIIaa-like | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| ISP domain | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Nop domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| HIT-like | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| vWA-like | 0 | Direct |
| Tautomerase/MIF | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| SAP domain | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| DNA clamp | 0 | Direct |
| Cystine-knot cytokines | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| LDL receptor-like module | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| BSD domain-like | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| BolA-like | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| eIF1-like | 0 | Direct |
| CalX-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Nucleic acid-binding proteins | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Kelch motif | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| Flavoproteins | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| TIMP-like | 0 | Direct |
| SAND domain-like | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| Translation proteins | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| PGBD-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Caspase-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Mss4-like | 0 | Direct |
| HMG-box | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| SH3-domain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIc | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| Periplasmic binding protein-like I | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| TGS-like | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| HAD-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Bet v1-like | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| L30e-like | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| UBA-like | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| SCP-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| PRTase-like | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| YbiA-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| R3H domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| ARM repeat | 0.01092 | Inherited |
| MFS general substrate transporter | 0.02984 | Inherited |
| RNA-binding domain, RBD | 0.06234 | Inherited |
| L domain-like | 0.06403 | Inherited |
| Ankyrin repeat | 0.145 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.1965 | Inherited |
| Immunoglobulin | 0.1979 | Inherited |
| EGF/Laminin | 0.2082 | Inherited |
| FYVE/PHD zinc finger | 0.3116 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.3439 | Inherited |
| Voltage-gated potassium channels | 0.3863 | Inherited |
| TPR-like | 0.3863 | Inherited |
| Homeodomain-like | 0.3874 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3932 | Inherited |
| Ubiquitin-like | 0.45 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.4596 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.4711 | Inherited |
| WD40 repeat-like | 0.4993 | Inherited |
| GTPase activation domain, GAP | 0.5566 | Inherited |
| Calponin-homology domain, CH-domain | 0.5693 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.5795 | Inherited |
| EF-hand | 0.5795 | Inherited |
| p53-like transcription factors | 0.5813 | Inherited |
| Cyclin-like | 0.5813 | Inherited |
| "Winged helix" DNA-binding domain | 0.5936 | Inherited |
| BAR/IMD domain-like | 0.5947 | Inherited |
| Lipocalins | 0.6087 | Inherited |
| SAM/Pointed domain | 0.6087 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.6904 | Inherited |
| Protein kinase-like (PK-like) | 0.7095 | Inherited |
| dsRNA-binding domain-like | 0.7863 | Inherited |
| LuxS/MPP-like metallohydrolase | 0.8403 | Inherited |
| Translation proteins SH3-like domain | 0.8403 | Inherited |
| Cysteine proteinases | 0.8589 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 0.8894 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.9292 | Inherited |
| Zn-binding ribosomal proteins | 0.9384 | Inherited |
| Thioredoxin-like | 0.9607 | Inherited |
| GST C-terminal domain-like | 0.9626 | Inherited |
| Trimeric LpxA-like enzymes | 0.977 | Inherited |
| S15/NS1 RNA-binding domain | 0.977 | Inherited |
| POZ domain | 0.9879 | Inherited |
| Class II aaRS and biotin synthetases | 0.9927 | Inherited |
| GINS helical bundle-like | 0.9954 | Inherited |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | Inherited |
| C-type lectin-like | 1 | Inherited |
| PAZ domain | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Nucleotidylyl transferase | 1 | Inherited |
| Histone-fold | 1 | Inherited |
| Insulin-like | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| Tudor domain | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Aldo-keto reductases (NADP) | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Ephrin ectodomain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Autophagin-like | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | DIRECT |
| beta-glycanases | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| H-NOX domain | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Purple acid phosphatase-like | 0 | DIRECT |
| Arylamine N-methyltransferase | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Integrin A (or I) domain | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Patatin | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| Internalin LRR domain | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Cyclophilin (peptidylprolyl isomerase) | 0 | DIRECT |
| Pseudouridine synthase I TruA | 0 | DIRECT |
| Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| PEP carboxykinase C-terminal domain | 0 | DIRECT |
| L-arabinose binding protein-like | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Laminin-type module | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| La domain | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| F-box domain | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Brix domain | 0 | DIRECT |
| Glycerol-3-phosphate transporter | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| Transforming growth factor (TGF)-beta | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Heme-dependent catalases | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Pepsin-like | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| GABA-aminotransferase-like | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| FabD-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Cytochrome b5 | 0 | DIRECT |
| Fatty acid binding protein-like | 0 | DIRECT |
| Astacin | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| Ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| TBP-associated factors, TAFs | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Rv2717c-like | 0 | DIRECT |
| PAPS sulfotransferase | 0 | DIRECT |
| NADPH-cytochrome p450 reductase-like | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| 28-residue LRR | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| Carboxylesterase | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Motor proteins | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| RUN domain | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Ribonuclease H | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| EGF-type module | 0 | DIRECT |
| Ganglioside M2 (gm2) activator | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| SPRY domain | 0 | DIRECT |
| Bacterial lipase | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| RIO1-like kinases | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| Diap1 N-terninal region-like | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Small Kunitz-type inhibitors & BPTI-like toxins | 0 | DIRECT |
| GAS2 domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
| Smr domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| L domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| STAR domain | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| N-acetyl transferase, NAT | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| Acireductone dioxygenase | 0 | DIRECT |
| PhzC/PhzF-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Ricin B-like | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| Osmotin, thaumatin-like protein | 0 | DIRECT |
| Cadherin | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| CalX-beta domain | 0 | DIRECT |
| MFPT repeat | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| PDZ domain | 0 | DIRECT |
| RING finger domain, C3HC4 | 0 | DIRECT |
| Acyl-CoA thioesterase | 0 | DIRECT |
| PhyH-like | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Nucleotide and nucleoside kinases | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| N-acetylglucosaminyltransferase I | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| Nitrogenase iron protein-like | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Mammalian PLC | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| ATI-like | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| AraD-like aldolase/epimerase | 0 | DIRECT |
| MSP-like | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| AlkB-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| CoA transferase alpha subunit-like | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| LacY-like proton/sugar symporter | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Papain-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| LDL receptor-like module | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| Cell cycle transcription factor e2f-dp | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Galectin (animal S-lectin) | 0 | DIRECT |
| MIF-related | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| Hermes transposase-like | 0 | DIRECT |
| Gastric lipase | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| Glutamine synthetase, N-terminal domain | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| Trehalase-like | 0 | DIRECT |
| SNF-like | 0 | DIRECT |
| Gelsolin-like | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| AMPK-beta glycogen binding domain-like | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Hemocyanin middle domain | 0 | DIRECT |
| Elongation factors | 0 | DIRECT |
| beta-CASP RNA-metabolising hydrolases | 0 | DIRECT |
| Pyridoxal-dependent decarboxylase | 0 | DIRECT |
| NLI interacting factor-like phosphatase | 0 | DIRECT |
| Classic zinc finger, C2H2 | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| LIM domain | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| Glutamine synthetase catalytic domain | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| BSD domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| YihX-like | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Cold shock DNA-binding domain-like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Synaptotagmin-like (S variant) | 0 | DIRECT |
| Multidomain sulfurtransferase (rhodanese) | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| EF-hand modules in multidomain proteins | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Family 19 glycosidase | 0 | DIRECT |
| UBX domain | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| CoA-binding domain | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| RNA methyltransferase FtsJ | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| PaaI/YdiI-like | 0 | DIRECT |
| Cdc48 N-terminal domain-like | 0 | DIRECT |
| Mo25 protein | 0 | DIRECT |
| Catalytic, N-terminal domain of histone methyltransferase Dot1l | 0 | DIRECT |
| Filamin repeat (rod domain) | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| Aminomethyltransferase folate-binding domain | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| I set domains | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Leukotriene A4 hydrolase catalytic domain | 0 | DIRECT |
| TatD Mg-dependent DNase-like | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| ZZ domain | 0 | DIRECT |
| Caspase catalytic domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| NagD-like | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| Canonical RBD | 0.127 | INHERITED FROM: P granule localization defective || egg morphology variant || oocytes disorganized || reproductive system morphology variant || developmental morphology variant || embryonic morphology variant || vulva morphology variant |
| Ankyrin repeat | 0.1695 | INHERITED FROM: fat |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.1695 | INHERITED FROM: fat || body size variant || body region morphology variant || organism segment morphology variant || short |
| G proteins | 0.1981 | INHERITED FROM: embryonic cell organization biogenesis variant || spindle position orientation defective early emb || fat || actin organization biogenesis variant || vesicle organization variant || seam cell morphology variant || mitotic spindle defective early emb || endoplasmic reticulum morphology variant || body region morphology variant || organism segment morphology variant || nuclear positioning variant || organ system morphology variant || multiple nuclei oocyte || cell morphology variant || dye filling defect || epithelial cell morphology variant || amphid phasmid neuron morphology variant || microtubule organization biogenesis variant |
| Calmodulin-like | 0.3931 | INHERITED FROM: annulae morphology variant |
| Nicotinic receptor ligand binding domain-like | 0.4242 | INHERITED FROM: fat || body size variant || body region morphology variant || organism segment morphology variant || short |
| Tetratricopeptide repeat (TPR) | 0.4595 | INHERITED FROM: organ system morphology variant || sexually dimorphic morphology variant || male morphology variant |
| HLH, helix-loop-helix DNA-binding domain | 0.4802 | INHERITED FROM: organ system morphology variant |
| Voltage-gated potassium channels | 0.4866 | INHERITED FROM: mitochondria morphology variant || dumpy || short |
| Tandem AAA-ATPase domain | 0.5019 | INHERITED FROM: reproductive system morphology variant || vulva morphology variant |
| Ubiquitin-related | 0.5712 | INHERITED FROM: nuclei small |
| Rhodopsin-like | 0.5722 | INHERITED FROM: fat |
| Calponin-homology domain, CH-domain | 0.5848 | INHERITED FROM: actin organization biogenesis variant || mitochondria alignment variant || cell morphology variant || muscle system morphology variant || body wall muscle myosin organization defective || striated muscle morphology variant |
| Protein kinases, catalytic subunit | 0.6209 | INHERITED FROM: mitochondrial content variant || germ nuclei rachis || mitochondria alignment variant || amphid neuron dye filling defect || myopodia present || rod like larval lethal || larval body morphology variant || muscle cell morphology variant |
| BCR-homology GTPase activation domain (BH-domain) | 0.6834 | INHERITED FROM: neurite morphology variant || axon branching variant || nervous system morphology variant || neuron morphology variant || mitochondria alignment variant || organ system morphology variant || mitochondria spacing variant || cell morphology variant || axon morphology variant || cell component morphology variant |
| Cyclin | 0.7452 | INHERITED FROM: pronuclear size defective early emb || embryonic cell organization biogenesis variant || multiple nuclei early emb || nuclear appearance number defective early emb || embryonic cell morphology variant || multiple cytoplasmic cavities early emb || pigmentation variant || organism pigmentation variant || nuclear morphology variation early emb || nuclear appearance variant || pronucleus centrosomes defective early emb || gonad arm morphology variant || pronuclear morphology defective early emb || excess pronucleus early emb || excess maternal pronucleus early emb || cytoplasmic appearance variant || nucleus defective early emb |
| Homeodomain | 0.7467 | INHERITED FROM: neuron positioning variant || nervous system morphology variant || body axis morphology variant || tail morphology variant || organism morphology variable || body region morphology variant || organism segment morphology variant || organ system morphology variant || sexually dimorphic morphology variant || male morphology variant |
| Forkhead DNA-binding domain | 0.7765 | INHERITED FROM: hermaphrodite reproductive system morphology variant || vulva morphology variant || sexually dimorphic morphology variant || male morphology variant |
| WD40-repeat | 0.8069 | INHERITED FROM: embryonic cell organization biogenesis variant || organ system morphology variant || vulva morphology variant || cell morphology variant || cytoplasmic morphology defective early emb || cephalic sensillum morphology variant |
| Extended AAA-ATPase domain | 0.8276 | INHERITED FROM: embryonic cell organization biogenesis variant || embryonic cell morphology variant || multiple cytoplasmic cavities early emb || endoplasmic reticulum morphology variant || cell cell contacts abnormal || cell cell contacts abnormal in four cell embryo || germ cell compartment small || meiotic spindle defective early emb || germ cell compartment anucleate || nucleus reforms cell division remnant early emb || cell component morphology variant || excessive blebbing early emb || cytoplasmic appearance variant || microtubule organization biogenesis variant |
| MPP-like | 0.8453 | INHERITED FROM: egg morphology variant || developmental morphology variant || embryonic morphology variant |
| BTB/POZ domain | 0.8725 | INHERITED FROM: embryonic cell organization biogenesis variant || cytoskeleton organization biogenesis variant || spindle position orientation defective early emb || cytoplasmic appearance defective early emb || spindle position defective early emb || spindle position variant || body axis morphology variant || mitotic spindle defective early emb || body morphology variant || body region morphology variant || organism segment morphology variant || cytoplasmic dynamics defective early emb || posterior body morphology variant || spindle defective early emb || excessive blebbing early emb || spindle variant || cytoplasmic appearance variant || organelle organization biogenesis variant || cell organization biogenesis variant || microtubule organization biogenesis variant |
| Adenain-like | 0.9749 | INHERITED FROM: pigmentation variant || organism pigmentation variant |
| Nucleosome core histones | 1 | INHERITED FROM: endosome morphology variant || gonad small || recycling endosome localization variant || intestinal degeneration || protruding vulva || vesicle organization variant || lysosome-related organelle morphology variant || thin || vulva morphology variant || cell component localization variant || cell morphology variant || vesicle morphology variant || RAB-11 recycling endosome localization variant || endosome localization variant || recycling endosome morphology variant |
| SH2 domain | 1 | INHERITED FROM: body wall muscle sarcomere morphology variant || mitochondria morphology variant || mitochondria alignment variant || mitochondria spacing variant || cell component localization variant || muscle system morphology variant || striated muscle morphology variant || muscle cell morphology variant |
| Insulin-like | 1 | INHERITED FROM: body length variant || body morphology variant || body region morphology variant || small || organism segment morphology variant || body width variant |
| Proteasome subunits | 1 | INHERITED FROM: endosome morphology variant || gonad morphology variant || recycling endosome localization variant || rachis morphology variant || cell membrane organization biogenesis variant || reproductive system morphology variant || gonad vesiculated || rachis narrow || vesicle organization variant || cell type morphology variant || lysosome-related organelle morphology variant || germ cell morphology variant || organ system morphology variant || germ cell compartment morphology variant || cell morphology variant || oocytes lack nucleus || vesicle morphology variant || cell component morphology variant || RAB-11 recycling endosome localization variant || recycling endosome morphology variant |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 1 | INHERITED FROM: oocyte number decreased || nuclei enlarged |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | INHERITED FROM: rachis morphology variant || pachytene region organization variant || oocyte number decreased || germ cell compartment expansion variant |
| C-type lectin domain | 1 | INHERITED FROM: tail swelling || rays displaced |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 1 | INHERITED FROM: gonad morphology variant || germline nuclear positioning variant || germ cell morphology variant || diakinesis region organization variant || cytoplasmic processing body variant || cell morphology variant || germ cell compartment anucleate || germ cell compartment expansion variant || cell component morphology variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| Tudor domain | 0 | Direct |
| GAPDH-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Aldo-keto reductases (NADP) | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| PDI-like | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Ephrin ectodomain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Autophagin-like | 0 | Direct |
| Reductases | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Prefoldin | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | Direct |
| beta-glycanases | 0 | Direct |
| BAR domain | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| MIR domain | 0 | Direct |
| H-NOX domain | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Purple acid phosphatase-like | 0 | Direct |
| Arylamine N-methyltransferase | 0 | Direct |
| SAP domain | 0 | Direct |
| Integrin A (or I) domain | 0 | Direct |
| FCH domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Patatin | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Nop domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| Internalin LRR domain | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Cyclophilin (peptidylprolyl isomerase) | 0 | Direct |
| Pseudouridine synthase I TruA | 0 | Direct |
| Phosphotyrosine-binding domain (PTB) | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Meta-cation ATPase, catalytic domain P | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| PEP carboxykinase C-terminal domain | 0 | Direct |
| L-arabinose binding protein-like | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Laminin-type module | 0 | Direct |
| UBC-related | 0 | Direct |
| Crotonase-like | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| La domain | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| TAZ domain | 0 | Direct |
| F-box domain | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Annexin | 0 | Direct |
| Brix domain | 0 | Direct |
| Glycerol-3-phosphate transporter | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| WW domain | 0 | Direct |
| Transforming growth factor (TGF)-beta | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Heme-dependent catalases | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| PX domain | 0 | Direct |
| Pepsin-like | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| WGR domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| SWIRM domain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| GABA-aminotransferase-like | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| First domain of FERM | 0 | Direct |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
| FF domain | 0 | Direct |
| Cullin repeat | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| CUT domain | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| FabD-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| PR-1-like | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| SMAD domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Cytochrome b5 | 0 | Direct |
| Fatty acid binding protein-like | 0 | Direct |
| Astacin | 0 | Direct |
| ARID domain | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| Ferredoxin domains from multidomain proteins | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| TBP-associated factors, TAFs | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| WWE domain | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Rv2717c-like | 0 | Direct |
| PAPS sulfotransferase | 0 | Direct |
| NADPH-cytochrome p450 reductase-like | 0 | Direct |
| Ras GEF | 0 | Direct |
| 28-residue LRR | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| Carboxylesterase | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| Motor proteins | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| Sema domain | 0 | Direct |
| RUN domain | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Ribonuclease H | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| COMT-like | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Hexokinase | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| EGF-type module | 0 | Direct |
| Ganglioside M2 (gm2) activator | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| SPRY domain | 0 | Direct |
| Bacterial lipase | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| PUA domain | 0 | Direct |
| U-box | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| RIO1-like kinases | 0 | Direct |
| Tetraspanin | 0 | Direct |
| Subtilases | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| Diap1 N-terninal region-like | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| MutT-like | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Small Kunitz-type inhibitors & BPTI-like toxins | 0 | Direct |
| GAS2 domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Glycogenin | 0 | Direct |
| D-aminoacid oxidase, N-terminal domain | 0 | Direct |
| Smr domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| L domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| STAR domain | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Phoshatidylinositol transfer protein, PITP | 0 | Direct |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| GYF domain | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| N-acetyl transferase, NAT | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| Acireductone dioxygenase | 0 | Direct |
| PhzC/PhzF-like | 0 | Direct |
| LysM domain | 0 | Direct |
| Ricin B-like | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| Osmotin, thaumatin-like protein | 0 | Direct |
| Cadherin | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| CalX-beta domain | 0 | Direct |
| MFPT repeat | 0 | Direct |
| Sec7 domain | 0 | Direct |
| PDZ domain | 0 | Direct |
| RING finger domain, C3HC4 | 0 | Direct |
| Acyl-CoA thioesterase | 0 | Direct |
| PhyH-like | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| Kelch motif | 0 | Direct |
| Nucleotide and nucleoside kinases | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| N-acetylglucosaminyltransferase I | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| Nitrogenase iron protein-like | 0 | Direct |
| MIT domain | 0 | Direct |
| Mammalian PLC | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Paired domain | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| Chromo domain | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| HEAT repeat | 0 | Direct |
| ATI-like | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| LEM domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| DEP domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| AraD-like aldolase/epimerase | 0 | Direct |
| MSP-like | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| eIF1-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| BolA-like | 0 | Direct |
| AlkB-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| CoA transferase alpha subunit-like | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| LacY-like proton/sugar symporter | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Troponin I | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Papain-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
| Tropomyosin | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| LDL receptor-like module | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| IF2B-like | 0 | Direct |
| Cell cycle transcription factor e2f-dp | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Galectin (animal S-lectin) | 0 | Direct |
| MIF-related | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
| Class I aldolase | 0 | Direct |
| Hermes transposase-like | 0 | Direct |
| Gastric lipase | 0 | Direct |
| VHS domain | 0 | Direct |
| Glutamine synthetase, N-terminal domain | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| Trehalase-like | 0 | Direct |
| SNF-like | 0 | Direct |
| Gelsolin-like | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| AMPK-beta glycogen binding domain-like | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Hemocyanin middle domain | 0 | Direct |
| Elongation factors | 0 | Direct |
| beta-CASP RNA-metabolising hydrolases | 0 | Direct |
| Pyridoxal-dependent decarboxylase | 0 | Direct |
| NLI interacting factor-like phosphatase | 0 | Direct |
| Classic zinc finger, C2H2 | 0 | Direct |
| YbiA-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Zf-UBP | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Integrin domains | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| LIM domain | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| SH3-domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| PDEase | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| Choline kinase | 0 | Direct |
| Elafin-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| ets domain | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| PP2C-like | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| Glutamine synthetase catalytic domain | 0 | Direct |
| Glutaminase | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| BSD domain | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| YihX-like | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| HMG-box | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Cold shock DNA-binding domain-like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Synaptotagmin-like (S variant) | 0 | Direct |
| Multidomain sulfurtransferase (rhodanese) | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| EF-hand modules in multidomain proteins | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Family 19 glycosidase | 0 | Direct |
| UBX domain | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| CoA-binding domain | 0 | Direct |
| UBA domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| FHA domain | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| RNA methyltransferase FtsJ | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| PaaI/YdiI-like | 0 | Direct |
| Cdc48 N-terminal domain-like | 0 | Direct |
| Mo25 protein | 0 | Direct |
| Catalytic, N-terminal domain of histone methyltransferase Dot1l | 0 | Direct |
| Filamin repeat (rod domain) | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| Aminomethyltransferase folate-binding domain | 0 | Direct |
| SAND domain | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| I set domains | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Leukotriene A4 hydrolase catalytic domain | 0 | Direct |
| TatD Mg-dependent DNase-like | 0 | Direct |
| NHL repeat | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| Plexin repeat | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| ZZ domain | 0 | Direct |
| Caspase catalytic domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| NagD-like | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| Canonical RBD | 0.127 | Inherited |
| Ankyrin repeat | 0.1695 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.1695 | Inherited |
| G proteins | 0.1981 | Inherited |
| Calmodulin-like | 0.3931 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.4242 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.4595 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.4802 | Inherited |
| Voltage-gated potassium channels | 0.4866 | Inherited |
| Tandem AAA-ATPase domain | 0.5019 | Inherited |
| Ubiquitin-related | 0.5712 | Inherited |
| Rhodopsin-like | 0.5722 | Inherited |
| Calponin-homology domain, CH-domain | 0.5848 | Inherited |
| Protein kinases, catalytic subunit | 0.6209 | Inherited |
| BCR-homology GTPase activation domain (BH-domain) | 0.6834 | Inherited |
| Cyclin | 0.7452 | Inherited |
| Homeodomain | 0.7467 | Inherited |
| Forkhead DNA-binding domain | 0.7765 | Inherited |
| WD40-repeat | 0.8069 | Inherited |
| Extended AAA-ATPase domain | 0.8276 | Inherited |
| MPP-like | 0.8453 | Inherited |
| BTB/POZ domain | 0.8725 | Inherited |
| Adenain-like | 0.9749 | Inherited |
| Nucleosome core histones | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| Proteasome subunits | 1 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 1 | Inherited |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | Inherited |
| C-type lectin domain | 1 | Inherited |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 1 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
 |
Plot tree as:
| |
Download Newick format tree:
|
(show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Mss4-like | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| SNF-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Concanavalin A-like lectins/glucanases | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Ganglioside M2 (gm2) activator | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| UBA-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| Pseudouridine synthase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| EB1 dimerisation domain-like | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Actin-crosslinking proteins | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| Hairpin loop containing domain-like | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| BPTI-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| CalX-like | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| SMR domain-like | 0 | DIRECT |
| Cystine-knot cytokines | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| BolA-like | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| Ricin B-like lectins | 0 | DIRECT |
| Nucleic acid-binding proteins | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| alpha-helical ferredoxin | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIc | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Glutamine synthetase, N-terminal domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Periplasmic binding protein-like I | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
| Tautomerase/MIF | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| LDL receptor-like module | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Osmotin, thaumatin-like protein | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Calcium ATPase, transduction domain A | 0 | DIRECT |
| Tudor/PWWP/MBT | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| SpoIIaa-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| ADC-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| ARM repeat | 0.009404 | INHERITED FROM: dye filling defect || cell morphology variant || seam cell morphology variant || organ system morphology variant || P granule localization defective || vulva morphology variant || developmental morphology variant || embryonic cell organization biogenesis variant || amphid phasmid neuron morphology variant || microtubule organization biogenesis variant || EMS anterior extension fails early emb || vesicle organization variant || pigmentation variant |
| MFS general substrate transporter | 0.02619 | INHERITED FROM: organism morphology variant |
| RNA-binding domain, RBD | 0.05554 | INHERITED FROM: embryonic morphology variant || cell morphology variant || P granule localization defective || vulva morphology variant || oocytes disorganized || developmental morphology variant || egg morphology variant || cuticle morphology variant || reproductive system morphology variant |
| L domain-like | 0.05708 | INHERITED FROM: myopodia present |
| Ankyrin repeat | 0.1323 | INHERITED FROM: fat |
| P-loop containing nucleoside triphosphate hydrolases | 0.1809 | INHERITED FROM: endoplasmic reticulum morphology variant || excessive blebbing early emb || cell morphology variant || organism segment morphology variant || embryonic cell morphology variant || organ system morphology variant || axon morphology variant || embryonic cell organization biogenesis variant || gonad arm morphology variant || lumpy || cell type morphology variant || actin organization biogenesis variant || cell cell contacts abnormal in four cell embryo || microtubule organization biogenesis variant || vesicle organization variant || body region morphology variant |
| Immunoglobulin | 0.1821 | INHERITED FROM: synapse morphology variant || cell morphology variant || organism segment morphology variant || myopodia present || body wall muscle sarcomere morphology variant || sperm pseudopod variant || mitochondria morphology variant || neuron morphology variant || muscle system morphology variant || neurite morphology variant || body region morphology variant || nervous system morphology variant || muscle cell morphology variant || sperm morphology variant |
| EGF/Laminin | 0.192 | INHERITED FROM: dumpy || rectal morphology variant || body wall muscle sarcomere morphology variant || clear || developmental morphology variant || axon trajectory variant || muscle cell morphology variant || no rectum |
| FYVE/PHD zinc finger | 0.2922 | INHERITED FROM: tail morphology variant |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.324 | INHERITED FROM: cell morphology variant || body wall muscle sarcomere morphology variant || mitochondria morphology variant || axon morphology variant || muscle system morphology variant || mitochondria alignment variant || striated muscle morphology variant || endomitotic oocytes |
| TPR-like | 0.3658 | INHERITED FROM: spindle variant || sensillum morphology variant || dye filling defect || cell morphology variant || sexually dimorphic morphology variant || mitotic spindle defective early emb || organ system morphology variant || male morphology variant || embryonic cell organization biogenesis variant || cilia morphology variant || pronucleus centrosomes defective early emb || ciliated neuron morphology variant || microtubule organization biogenesis variant |
| Voltage-gated potassium channels | 0.3658 | INHERITED FROM: dumpy || body wall muscle sarcomere morphology variant || short || mitochondria morphology variant || muscle system morphology variant || striated muscle morphology variant || muscle cell morphology variant |
| Homeodomain-like | 0.3669 | INHERITED FROM: organism segment morphology variant || sexually dimorphic morphology variant || neuron positioning variant || organ system morphology variant || male morphology variant || tail morphology variant || body axis morphology variant || body region morphology variant || organism morphology variable || nervous system morphology variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3727 | INHERITED FROM: organism segment morphology variant || short || body size variant || fat || body region morphology variant |
| Ubiquitin-like | 0.4291 | INHERITED FROM: cell morphology variant |
| HLH, helix-loop-helix DNA-binding domain | 0.4385 | INHERITED FROM: organ system morphology variant |
| Ribosomal protein S5 domain 2-like | 0.4499 | INHERITED FROM: germ cell compartment expansion variant || nuclear appearance variant |
| WD40 repeat-like | 0.4777 | INHERITED FROM: endosome morphology variant || cell morphology variant || organ system morphology variant || vulva morphology variant || vesicle morphology variant || embryonic cell organization biogenesis variant || cytoplasmic morphology defective early emb || early endosome morphology variant || vesicle organization variant |
| GTPase activation domain, GAP | 0.5347 | INHERITED FROM: cell morphology variant || organ system morphology variant || neuron morphology variant || axon morphology variant || mitochondria alignment variant || neurite morphology variant || axon branching variant || nervous system morphology variant || mitochondria spacing variant |
| Calponin-homology domain, CH-domain | 0.5476 | INHERITED FROM: body wall muscle myosin organization defective || cell morphology variant || organ system morphology variant || pronuclear nuclear appearance variant emb || muscle system morphology variant || mitochondria alignment variant || striated muscle morphology variant || actin organization biogenesis variant |
| Nicotinic receptor ligand binding domain-like | 0.5577 | INHERITED FROM: organism segment morphology variant || short || body size variant || fat || body region morphology variant |
| EF-hand | 0.5577 | INHERITED FROM: annulae morphology variant || endomitotic oocytes |
| Cyclin-like | 0.5594 | INHERITED FROM: excess maternal pronucleus early emb || nuclear appearance number defective early emb || cytoplasmic appearance variant || embryonic cell morphology variant || pronuclear morphology defective early emb || multiple cytoplasmic cavities early emb || pronuclear size defective early emb || embryonic cell organization biogenesis variant || excess pronucleus early emb || organism pigmentation variant || multiple nuclei early emb || pronucleus centrosomes defective early emb || nuclear morphology variation early emb || nucleus defective early emb || pigmentation variant |
| p53-like transcription factors | 0.5594 | INHERITED FROM: alimentary system morphology variant || developmental morphology variant || epithelial system morphology variant || epithelial morphology variant |
| "Winged helix" DNA-binding domain | 0.5715 | INHERITED FROM: cell morphology variant || mitotic spindle defective early emb || organ system morphology variant || vulva morphology variant || embryonic cell organization biogenesis variant || age associated fluorescence increased || spindle rotation variant || rachis absent || microtubule organization biogenesis variant || reproductive system morphology variant |
| BAR/IMD domain-like | 0.5727 | INHERITED FROM: amphid phasmid sensillum morphology variant || dye filling defect |
| SAM/Pointed domain | 0.5867 | INHERITED FROM: synapse morphology variant |
| Lipocalins | 0.5867 | INHERITED FROM: developmental pigmentation variant || age associated fluorescence increased |
| NAD(P)-binding Rossmann-fold domains | 0.6693 | INHERITED FROM: fat associated bodies variant || vulval invagination variant L4 |
| Protein kinase-like (PK-like) | 0.6889 | INHERITED FROM: mitochondrial content variant || myopodia present || germ nuclei rachis || mitochondria alignment variant || rod like larval lethal || muscle cell morphology variant || mitochondria spacing variant |
| dsRNA-binding domain-like | 0.7677 | INHERITED FROM: pericellular component morphology variant || alae morphology variant || germ cell morphology variant || cytoplasmic processing body variant || cuticle morphology variant |
| Translation proteins SH3-like domain | 0.8229 | INHERITED FROM: organ system morphology variant || oocyte number decreased || germ cell compartment expansion variant || germ cell morphology variant || cell component morphology variant || cell membrane organization biogenesis variant || rachis narrow || cell type morphology variant || gonad vesiculated || pachytene region organization variant || rachis morphology variant |
| LuxS/MPP-like metallohydrolase | 0.8229 | INHERITED FROM: embryonic morphology variant || developmental morphology variant || egg morphology variant |
| Cysteine proteinases | 0.8426 | INHERITED FROM: developmental pigmentation variant |
| (Phosphotyrosine protein) phosphatases II | 0.8742 | INHERITED FROM: mitochondria alignment variant || mitochondria spacing variant |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.9153 | INHERITED FROM: endosome morphology variant || cell morphology variant || recycling endosome localization variant || gonad morphology variant || vesicle morphology variant || germ cell morphology variant || recycling endosome morphology variant || cell component morphology variant || RAB-11 recycling endosome localization variant || oocytes lack nucleus || cell membrane organization biogenesis variant || rachis narrow || cell type morphology variant || gonad vesiculated || germ cell compartment morphology variant || vesicle organization variant || lysosome-related organelle morphology variant || reproductive system morphology variant || rachis morphology variant |
| Zn-binding ribosomal proteins | 0.9246 | INHERITED FROM: organism segment morphology variant || germ cell morphology variant || body morphology variant || cytoplasmic processing body variant || body size variant || body width variant || body region morphology variant || reproductive system morphology variant |
| Thioredoxin-like | 0.9478 | INHERITED FROM: pseudocoelom morphology variant |
| Family A G protein-coupled receptor-like | 0.9497 | INHERITED FROM: organism morphology variant |
| GST C-terminal domain-like | 0.9499 | INHERITED FROM: pseudocoelom morphology variant |
| Trimeric LpxA-like enzymes | 0.9652 | INHERITED FROM: cell morphology variant |
| S15/NS1 RNA-binding domain | 0.9652 | INHERITED FROM: oocyte morphology variant || gonad morphology variant || germ cell compartment expansion variant || germ cell morphology variant || rachis narrow || germ cell compartment morphology variant || pachytene region organization variant || rachis morphology variant |
| POZ domain | 0.9771 | INHERITED FROM: posterior body morphology variant || spindle variant || spindle position variant || excessive blebbing early emb || cytoplasmic appearance variant || cytoplasmic appearance defective early emb || mitotic spindle defective early emb || embryonic cell organization biogenesis variant || spindle position orientation defective early emb || spindle position defective early emb || cytoskeleton organization biogenesis variant || spindle defective early emb || body axis morphology variant || cytoplasmic dynamics defective early emb || microtubule organization biogenesis variant |
| Class II aaRS and biotin synthetases | 0.9822 | INHERITED FROM: germline nuclear positioning variant || cell morphology variant || germ cell compartment anucleate || organ system morphology variant || diakinesis region organization variant || germ cell compartment expansion variant || germ cell morphology variant || cell component morphology variant || cytoplasmic processing body variant |
| GINS helical bundle-like | 0.9849 | INHERITED FROM: hermaphrodite reproductive system morphology variant || protruding vulva || vulva morphology variant || reproductive system morphology variant |
| PAZ domain | 1 | INHERITED FROM: alae morphology variant || breaks in alae |
| Insulin-like | 1 | INHERITED FROM: body length variant || organism segment morphology variant || body morphology variant || small || body width variant || body region morphology variant |
| SH2 domain | 1 | INHERITED FROM: cell component localization variant || body wall muscle sarcomere morphology variant || mitochondria morphology variant || muscle system morphology variant || mitochondria alignment variant || striated muscle morphology variant || muscle cell morphology variant || mitochondria spacing variant |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | INHERITED FROM: germline nuclear positioning variant || oocyte morphology variant || oocyte number decreased || gonad morphology variant || germ cell compartment expansion variant || nuclei enlarged || germ cell compartment morphology variant || pachytene region organization variant || rachis morphology variant |
| Nucleotidylyl transferase | 1 | INHERITED FROM: nuclei enlarged |
| C-type lectin-like | 1 | INHERITED FROM: tail swelling || rays displaced |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: protruding vulva || sexually dimorphic morphology variant || organ system morphology variant || male morphology variant |
| Histone-fold | 1 | INHERITED FROM: thin || cell component localization variant || endosome morphology variant || intestinal degeneration || protruding vulva || cell morphology variant || intestinal morphology variant || recycling endosome localization variant || gonad small || vesicle morphology variant || recycling endosome morphology variant || RAB-11 recycling endosome localization variant || endosome localization variant || vesicle organization variant || lysosome-related organelle morphology variant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Mss4-like | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| SAP domain | 0 | Direct |
| HMG-box | 0 | Direct |
| PH domain-like | 0 | Direct |
| HAD-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| NTF2-like | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| SNF-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| Concanavalin A-like lectins/glucanases | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| SNARE-like | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| KA1-like | 0 | Direct |
| Ganglioside M2 (gm2) activator | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Sema domain | 0 | Direct |
| Elafin-like | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| UBA-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| PUA domain-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Tim10-like | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| SH3-domain | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| Pseudouridine synthase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| EB1 dimerisation domain-like | 0 | Direct |
| BSD domain-like | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| Nudix | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Actin-crosslinking proteins | 0 | Direct |
| ARID-like | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| Lysozyme-like | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| Hairpin loop containing domain-like | 0 | Direct |
| PGBD-like | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| TAZ domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Integrin domains | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| PIN domain-like | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| LEM domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| R3H domain | 0 | Direct |
| LysM domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| CBD9-like | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| YbiA-like | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| SET domain | 0 | Direct |
| WW domain | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| L30e-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| RUN domain-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| DNA clamp | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| BPTI-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Kelch motif | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| MIT domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cupredoxins | 0 | Direct |
| Aldolase | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| CalX-like | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| HCP-like | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| SMR domain-like | 0 | Direct |
| Cystine-knot cytokines | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| VPS9 domain | 0 | Direct |
| BolA-like | 0 | Direct |
| TIMP-like | 0 | Direct |
| Ricin B-like lectins | 0 | Direct |
| Nucleic acid-binding proteins | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| Flavoproteins | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| PRTase-like | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| GroES-like | 0 | Direct |
| Bet v1-like | 0 | Direct |
| Polo-box domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| alpha-helical ferredoxin | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| BEACH domain | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIc | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| eIF1-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| FF domain | 0 | Direct |
| Glutamine synthetase, N-terminal domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| NHL repeat | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| Kringle-like | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| DNase I-like | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| SCP-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Nop domain | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| Translation proteins | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Caspase-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| ISP domain | 0 | Direct |
| PR-1-like | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| SIS domain | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Periplasmic binding protein-like I | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Cytochrome c | 0 | Direct |
| UBC-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| HIT-like | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| DEATH domain | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Acid proteases | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| MIR domain | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| ACP-like | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| SAND domain-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| Pentein | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| TGS-like | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| vWA-like | 0 | Direct |
| Multidrug resistance efflux transporter EmrE | 0 | Direct |
| Tautomerase/MIF | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| PX domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| PapD-like | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| LDL receptor-like module | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| PP2C-like | 0 | Direct |
| GYF domain | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Osmotin, thaumatin-like protein | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Ras GEF | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Calcium ATPase, transduction domain A | 0 | Direct |
| Tudor/PWWP/MBT | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| SpoIIaa-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| WWE domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| ADC-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| ARM repeat | 0.009404 | Inherited |
| MFS general substrate transporter | 0.02619 | Inherited |
| RNA-binding domain, RBD | 0.05554 | Inherited |
| L domain-like | 0.05708 | Inherited |
| Ankyrin repeat | 0.1323 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.1809 | Inherited |
| Immunoglobulin | 0.1821 | Inherited |
| EGF/Laminin | 0.192 | Inherited |
| FYVE/PHD zinc finger | 0.2922 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.324 | Inherited |
| TPR-like | 0.3658 | Inherited |
| Voltage-gated potassium channels | 0.3658 | Inherited |
| Homeodomain-like | 0.3669 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3727 | Inherited |
| Ubiquitin-like | 0.4291 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.4385 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.4499 | Inherited |
| WD40 repeat-like | 0.4777 | Inherited |
| GTPase activation domain, GAP | 0.5347 | Inherited |
| Calponin-homology domain, CH-domain | 0.5476 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.5577 | Inherited |
| EF-hand | 0.5577 | Inherited |
| Cyclin-like | 0.5594 | Inherited |
| p53-like transcription factors | 0.5594 | Inherited |
| "Winged helix" DNA-binding domain | 0.5715 | Inherited |
| BAR/IMD domain-like | 0.5727 | Inherited |
| SAM/Pointed domain | 0.5867 | Inherited |
| Lipocalins | 0.5867 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.6693 | Inherited |
| Protein kinase-like (PK-like) | 0.6889 | Inherited |
| dsRNA-binding domain-like | 0.7677 | Inherited |
| Translation proteins SH3-like domain | 0.8229 | Inherited |
| LuxS/MPP-like metallohydrolase | 0.8229 | Inherited |
| Cysteine proteinases | 0.8426 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 0.8742 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.9153 | Inherited |
| Zn-binding ribosomal proteins | 0.9246 | Inherited |
| Thioredoxin-like | 0.9478 | Inherited |
| Family A G protein-coupled receptor-like | 0.9497 | Inherited |
| GST C-terminal domain-like | 0.9499 | Inherited |
| Trimeric LpxA-like enzymes | 0.9652 | Inherited |
| S15/NS1 RNA-binding domain | 0.9652 | Inherited |
| POZ domain | 0.9771 | Inherited |
| Class II aaRS and biotin synthetases | 0.9822 | Inherited |
| GINS helical bundle-like | 0.9849 | Inherited |
| PAZ domain | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | Inherited |
| Nucleotidylyl transferase | 1 | Inherited |
| C-type lectin-like | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Histone-fold | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54368,55931
54368 - Glutamine synthetase, N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
141072,141072
141072 - CalX-like
141072 - CalX-like | 0 | DIRECT |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | DIRECT |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | DIRECT |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | DIRECT |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
51126,51126
51126 - Pectin lyase-like
51126 - Pectin lyase-like | 0 | DIRECT |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
48403,52113
48403 - Ankyrin repeat
52113 - BRCT domain | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | DIRECT |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
54495,57850
54495 - UBC-like
57850 - RING/U-box | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
49363,56300
49363 - Purple acid phosphatase, N-terminal domain
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
52821,52821
52821 - Rhodanese/Cell cycle control phosphatase
52821 - Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3727 | INHERITED FROM: organism segment morphology variant || short || body size variant || fat || body region morphology variant |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0.8229 | INHERITED FROM: embryonic morphology variant || developmental morphology variant || egg morphology variant |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.9358 | INHERITED FROM: intestinal morphology variant || sexually dimorphic morphology variant || organ system morphology variant || male morphology variant |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.9416 | INHERITED FROM: endoplasmic reticulum morphology variant || meiotic spindle defective early emb |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.983 | INHERITED FROM: pseudocoelom morphology variant |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 1 | INHERITED FROM: mitochondria alignment variant || mitochondria spacing variant |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | INHERITED FROM: oocyte morphology variant || oocyte number decreased || gonad morphology variant || germ cell compartment expansion variant || nuclear appearance variant || nuclei enlarged || germ cell compartment morphology variant || pachytene region organization variant || rachis morphology variant |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54368,55931
54368 - Glutamine synthetase, N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
55486,49854
55486 - Metalloproteases ("zincins"), catalytic domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
141072,141072
141072 - CalX-like
141072 - CalX-like | 0 | Direct |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | Direct |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | Direct |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | Direct |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0 | Direct |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
51126,51126
51126 - Pectin lyase-like
51126 - Pectin lyase-like | 0 | Direct |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
103473,100895
103473 - MFS general substrate transporter
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
48403,52113
48403 - Ankyrin repeat
52113 - BRCT domain | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | Direct |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
54495,57850
54495 - UBC-like
57850 - RING/U-box | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
49363,56300
49363 - Purple acid phosphatase, N-terminal domain
56300 - Metallo-dependent phosphatases | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
52821,52821
52821 - Rhodanese/Cell cycle control phosphatase
52821 - Rhodanese/Cell cycle control phosphatase | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3727 | Inherited |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0.8229 | Inherited |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.9358 | Inherited |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.9416 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.983 | Inherited |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 1 | Inherited |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
90257,90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.7677 | INHERITED FROM: sexually dimorphic morphology variant || male morphology variant || amphid phasmid neuron morphology variant |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
90257,90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.7677 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
|
Plot tree as:
| |
Download Newick format tree:
|
(show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
