|
|
Worm Phenotype (WP): chemical response variant
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0.00000000002208 | DIRECT |
| Nicotinic receptor ligand binding domain-like | 0.0000000003902 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.0000000006707 | DIRECT |
| Cullin repeat-like | 0.00000005515 | DIRECT |
| Protein kinase-like (PK-like) | 0.0000001634 | DIRECT |
| Cullin homology domain | 0.000002838 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0.000016 | DIRECT |
| Nucleotide cyclase | 0.0000186 | DIRECT |
| cAMP-binding domain-like | 0.00005029 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.0002063 | DIRECT |
| ABC transporter transmembrane region | 0.0007162 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0007667 | DIRECT |
| Periplasmic binding protein-like I | 0.005545 | INHERITED FROM: alkaline pH chemotaxis variant || lithium chemotaxis defective || diacetyl chemotaxis variant || bromide chemotaxis variant || magnesium chemotaxis defective || aqueous chemosensory response variant || bromide chemotaxis defective || chemosensory response variant || AWC odorant chemotaxis variant || benzaldehyde chemotaxis variant || iodide chemotaxis defective || carbon dioxide avoidance variant || aqueous positive chemotaxis variant || carbon dioxide response variant || iodide chemotaxis variant || chemotaxis variant || AWC odorant chemotaxis defective |
| Cation efflux protein transmembrane domain-like | 0.006722 | INHERITED FROM: manganese response variant || cadmium hypersensitive || manganese toxicity resistant |
| t-snare proteins | 0.008616 | INHERITED FROM: drug hypersensitive |
| Myosin rod fragments | 0.008616 | INHERITED FROM: drug resistant |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.009642 | INHERITED FROM: paraquat response variant || organism toxic chemical response variant |
| Cation efflux protein cytoplasmic domain-like | 0.009642 | INHERITED FROM: chemical hypersensitive || cadmium hypersensitive |
| EF-hand | 0.01717 | INHERITED FROM: aldicarb response variant |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.04682 | INHERITED FROM: drug hypersensitive |
| PRTase-like | 0.0492 | INHERITED FROM: Fluorouracil resistant || drug resistant |
| Lipovitellin-phosvitin complex, superhelical domain | 0.06109 | INHERITED FROM: unfolded protein response variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.06109 | INHERITED FROM: unfolded protein response variant |
| Spectrin repeat | 0.06109 | INHERITED FROM: drug response variant || aldicarb response variant |
| ENTH/VHS domain | 0.06276 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant |
| TPR-like | 0.07014 | INHERITED FROM: positive chemotaxis defective || ivermectin response variant || ivermectin resistant || chemotaxis variant |
| Voltage-gated potassium channels | 0.07934 | INHERITED FROM: serotonin resistant || positive chemotaxis defective || serotonin response variant || imipramine resistant || phentolamine resistant || adrenergic receptor antagonist response variant |
| Periplasmic binding protein-like II | 0.08303 | INHERITED FROM: positive chemotaxis defective || aqueous positive chemotaxis defective || sodium chloride chemotaxis variant || chemosensory response variant || response to food variant || aqueous positive chemotaxis variant || sodium chloride chemotaxis defective || chemotaxis variant |
| Immunoglobulin | 0.08779 | INHERITED FROM: aldicarb response variant |
| Cytochrome P450 | 0.08779 | INHERITED FROM: cadmium hypersensitive |
| Calcium ATPase, transmembrane domain M | 0.09099 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.09099 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive |
| Calcium ATPase, transduction domain A | 0.09099 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive |
| Troponin coil-coiled subunits | 0.1022 | INHERITED FROM: nicotine response variant || drug response variant |
| SH3-domain | 0.1112 | INHERITED FROM: aldicarb response variant |
| Regulator of G-protein signaling, RGS | 0.1267 | INHERITED FROM: negative chemotaxis variant || chemotaxis variant |
| SAM/Pointed domain | 0.1267 | INHERITED FROM: aldicarb response variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1321 | INHERITED FROM: positive chemotaxis defective || odorant chemosensory response variant || odorant positive chemotaxis defective || chemotaxis variant |
| PDZ domain-like | 0.1371 | INHERITED FROM: chemical resistant || aldicarb response variant || acetylcholinesterase inhibitor response variant || drug resistant |
| WD40 repeat-like | 0.1504 | INHERITED FROM: osmotic avoidance variant || aldicarb response variant |
| Cysteine-rich domain | 0.1684 | INHERITED FROM: positive chemotaxis variant || odorant positive chemotaxis variant || odorant chemosensory response variant || aldicarb response variant || acetylcholinesterase inhibitor response variant |
| PYP-like sensor domain (PAS domain) | 0.1701 | INHERITED FROM: anesthetic response variant || carbon dioxide avoidance variant || carbon dioxide response variant |
| SNARE-like | 0.1882 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant |
| PH domain-like | 0.1967 | INHERITED FROM: aldicarb response variant |
| EGF/Laminin | 0.2372 | INHERITED FROM: odorant negative chemotaxis defective || octanol chemotaxis variant || octanol chemotaxis defective |
| Glutathione synthetase ATP-binding domain-like | 0.2424 | INHERITED FROM: negative chemotaxis variant || osmotic avoidance variant || chemotaxis variant |
| "Winged helix" DNA-binding domain | 0.2549 | INHERITED FROM: anesthetic response variant |
| SNF-like | 0.2791 | INHERITED FROM: drug hypersensitive |
| HMG-box | 0.2791 | INHERITED FROM: anesthetic response variant |
| HAD-like | 0.3027 | INHERITED FROM: nicotine hypersensitive |
| Cystine-knot cytokines | 0.3365 | INHERITED FROM: nicotine response variant || levamisole response variant |
| P-loop containing nucleoside triphosphate hydrolases | 0.3526 | INHERITED FROM: aldicarb response variant || carbon dioxide avoidance variant || chemotaxis variant |
| GroEL-intermediate domain like | 0.3575 | INHERITED FROM: unfolded protein response variant |
| GroEL equatorial domain-like | 0.3575 | INHERITED FROM: unfolded protein response variant |
| WW domain | 0.3575 | INHERITED FROM: aldicarb resistant |
| Lipocalins | 0.3575 | INHERITED FROM: paraquat hypersensitive |
| GroEL apical domain-like | 0.3575 | INHERITED FROM: unfolded protein response variant |
| FAD/NAD(P)-binding domain | 0.3843 | INHERITED FROM: organism toxic chemical response variant |
| Bromodomain | 0.4737 | INHERITED FROM: anesthetic response variant || drug adaptation variant || ethanol resistant || anesthetic resistant || acute functional tolerance to alcohol defective |
| Homeodomain-like | 0.4802 | INHERITED FROM: egg laying imipramine resistant || imipramine resistant || carbon dioxide avoidance variant || carbon dioxide response variant || phentolamine resistant || adrenergic receptor antagonist response variant |
| Cysteine proteinases | 0.4837 | INHERITED FROM: paraquat hypersensitive |
| HSP20-like chaperones | 0.5684 | INHERITED FROM: cadmium hypersensitive |
| Tubulin nucleotide-binding domain-like | 0.5684 | INHERITED FROM: nicotine response variant |
| DBL homology domain (DH-domain) | 0.5998 | INHERITED FROM: aldicarb response variant |
| Thioredoxin-like | 0.6485 | INHERITED FROM: paraquat response variant || organism toxic chemical response variant |
| Leucine zipper domain | 0.7015 | INHERITED FROM: pore forming toxin response variant |
| Tubulin C-terminal domain-like | 0.7015 | INHERITED FROM: nicotine response variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.841 | INHERITED FROM: SDS sensitive dauer |
| GST C-terminal domain-like | 0.8925 | INHERITED FROM: cadmium hypersensitive |
| HLH, helix-loop-helix DNA-binding domain | 0.8967 | INHERITED FROM: aqueous positive chemotaxis defective || lysine chemotaxis defective |
| Sm-like ribonucleoproteins | 0.9659 | INHERITED FROM: unfolded protein response variant |
| Ankyrin repeat | 1 | INHERITED FROM: odorant negative chemotaxis defective || chemosensory response variant || octanol chemotaxis variant || octanol chemotaxis defective || chemotaxis variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: inhibitor of serotonin uptake variant || egg laying imipramine resistant || imipramine resistant |
| Nucleotidylyl transferase | 1 | INHERITED FROM: paraquat resistant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: male tail curling serotonin variant || locomotion rate serotonin variant || serotonin induced pumping variant || serotonin induced fat reduction variant |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: hydroxyurea response variant || hydroxyurea hypersensitive |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer |
| MFS general substrate transporter | 1 | INHERITED FROM: organism high sodium chloride hypersensitive |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Skp1 dimerisation domain-like | 0.00000000002208 | Direct |
| Nicotinic receptor ligand binding domain-like | 0.0000000003902 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.0000000006707 | Direct |
| Cullin repeat-like | 0.00000005515 | Direct |
| Protein kinase-like (PK-like) | 0.0000001634 | Direct |
| Cullin homology domain | 0.000002838 | Direct |
| Transducin (alpha subunit), insertion domain | 0.000016 | Direct |
| Nucleotide cyclase | 0.0000186 | Direct |
| cAMP-binding domain-like | 0.00005029 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.0002063 | Direct |
| ABC transporter transmembrane region | 0.0007162 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0007667 | Direct |
| Periplasmic binding protein-like I | 0.005545 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.006722 | Inherited |
| t-snare proteins | 0.008616 | Inherited |
| Myosin rod fragments | 0.008616 | Inherited |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.009642 | Inherited |
| Cation efflux protein cytoplasmic domain-like | 0.009642 | Inherited |
| EF-hand | 0.01717 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.04682 | Inherited |
| PRTase-like | 0.0492 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.06109 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.06109 | Inherited |
| Spectrin repeat | 0.06109 | Inherited |
| ENTH/VHS domain | 0.06276 | Inherited |
| TPR-like | 0.07014 | Inherited |
| Voltage-gated potassium channels | 0.07934 | Inherited |
| Periplasmic binding protein-like II | 0.08303 | Inherited |
| Immunoglobulin | 0.08779 | Inherited |
| Cytochrome P450 | 0.08779 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.09099 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.09099 | Inherited |
| Calcium ATPase, transduction domain A | 0.09099 | Inherited |
| Troponin coil-coiled subunits | 0.1022 | Inherited |
| SH3-domain | 0.1112 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1267 | Inherited |
| SAM/Pointed domain | 0.1267 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1321 | Inherited |
| PDZ domain-like | 0.1371 | Inherited |
| WD40 repeat-like | 0.1504 | Inherited |
| Cysteine-rich domain | 0.1684 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.1701 | Inherited |
| SNARE-like | 0.1882 | Inherited |
| PH domain-like | 0.1967 | Inherited |
| EGF/Laminin | 0.2372 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 0.2424 | Inherited |
| "Winged helix" DNA-binding domain | 0.2549 | Inherited |
| SNF-like | 0.2791 | Inherited |
| HMG-box | 0.2791 | Inherited |
| HAD-like | 0.3027 | Inherited |
| Cystine-knot cytokines | 0.3365 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.3526 | Inherited |
| GroEL-intermediate domain like | 0.3575 | Inherited |
| GroEL equatorial domain-like | 0.3575 | Inherited |
| WW domain | 0.3575 | Inherited |
| Lipocalins | 0.3575 | Inherited |
| GroEL apical domain-like | 0.3575 | Inherited |
| FAD/NAD(P)-binding domain | 0.3843 | Inherited |
| Bromodomain | 0.4737 | Inherited |
| Homeodomain-like | 0.4802 | Inherited |
| Cysteine proteinases | 0.4837 | Inherited |
| HSP20-like chaperones | 0.5684 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.5684 | Inherited |
| DBL homology domain (DH-domain) | 0.5998 | Inherited |
| Thioredoxin-like | 0.6485 | Inherited |
| Leucine zipper domain | 0.7015 | Inherited |
| Tubulin C-terminal domain-like | 0.7015 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.841 | Inherited |
| GST C-terminal domain-like | 0.8925 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.8967 | Inherited |
| Sm-like ribonucleoproteins | 0.9659 | Inherited |
| Ankyrin repeat | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Nucleotidylyl transferase | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| MFS general substrate transporter | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (SDWP level: Moderately Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Cullin repeat | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Nicotinic receptor ligand binding domain-like | 0.000000001038 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.000000001038 | DIRECT |
| Skp1 dimerisation domain-like | 0.000000001677 | DIRECT |
| Protein kinases, catalytic subunit | 0.000001132 | DIRECT |
| Cullin homology domain | 0.000007587 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0.00001676 | DIRECT |
| Adenylyl and guanylyl cyclase catalytic domain | 0.00002047 | DIRECT |
| cAMP-binding domain | 0.00007263 | DIRECT |
| ABC transporter transmembrane region | 0.00118 | INHERITED FROM: chemical hypersensitive || colchicine hypersensitive || cadmium hypersensitive |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.001271 | INHERITED FROM: hydroxyurea response variant || hydroxyurea hypersensitive || drug hypersensitive |
| H-NOX domain | 0.001493 | INHERITED FROM: anesthetic response variant || drug response variant || carbon dioxide avoidance variant || carbon dioxide response variant |
| Eps15 homology domain (EH domain) | 0.001493 | INHERITED FROM: drug response variant || aldicarb response variant || acetylcholinesterase inhibitor response variant |
| BTB/POZ domain | 0.00547 | INHERITED FROM: chemical hypersensitive |
| Transforming growth factor (TGF)-beta | 0.00606 | INHERITED FROM: nicotine response variant || drug response variant || levamisole response variant |
| Cation efflux protein cytoplasmic domain-like | 0.00606 | INHERITED FROM: chemical hypersensitive || cadmium hypersensitive |
| PLC-like (P variant) | 0.01166 | INHERITED FROM: positive chemotaxis variant || aldicarb response variant |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.01501 | INHERITED FROM: paraquat response variant || organism toxic chemical response variant |
| t-snare proteins | 0.01519 | INHERITED FROM: drug hypersensitive |
| L-arabinose binding protein-like | 0.01619 | INHERITED FROM: alkaline pH chemotaxis variant || lithium chemotaxis defective || anion positive chemotaxis defective || anion positive chemotaxis variant || bromide chemotaxis variant || magnesium chemotaxis defective || cation positive chemotaxis variant || bromide chemotaxis defective || chemosensory response variant || iodide chemotaxis defective || cation positive chemotaxis defective || aqueous positive chemotaxis variant || iodide chemotaxis variant || chemotaxis variant |
| Cation efflux protein transmembrane domain-like | 0.02551 | INHERITED FROM: chemical hypersensitive || manganese response variant || cadmium hypersensitive || manganese toxicity resistant |
| G proteins | 0.0261 | INHERITED FROM: anesthetic response variant || drug response variant || chemosensory response variant || aldicarb response variant || carbon dioxide avoidance variant || chemotaxis variant |
| Phosphoribosyltransferases (PRTases) | 0.02925 | INHERITED FROM: Fluorouracil resistant || chemical resistant || drug resistant |
| Clathrin coat assembly domain | 0.02925 | INHERITED FROM: acetylcholinesterase inhibitor resistant || chemical resistant || aldicarb response variant || acetylcholinesterase inhibitor response variant || aldicarb resistant || drug resistant |
| I set domains | 0.03294 | INHERITED FROM: aldicarb response variant |
| Synaptotagmin-like (S variant) | 0.03376 | INHERITED FROM: acetylcholinesterase inhibitor resistant || chemical resistant || drug response variant || acetylcholinesterase inhibitor response variant || drug resistant |
| ABC transporter ATPase domain-like | 0.04774 | INHERITED FROM: chemical hypersensitive || colchicine hypersensitive || cadmium hypersensitive |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.05706 | INHERITED FROM: paraquat response variant || organism toxic chemical response variant |
| Lipovitellin-phosvitin complex, superhelical domain | 0.05706 | INHERITED FROM: unfolded protein response variant |
| Spectrin repeat | 0.05706 | INHERITED FROM: drug response variant || aldicarb response variant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.05706 | INHERITED FROM: unfolded protein response variant |
| Pyridoxal-dependent decarboxylase | 0.05706 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant || egg laying response to drug variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.06154 | INHERITED FROM: positive chemotaxis defective || odorant chemosensory response variant || odorant positive chemotaxis defective || chemotaxis variant |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.07787 | INHERITED FROM: drug hypersensitive |
| Phosphate binding protein-like | 0.07957 | INHERITED FROM: positive chemotaxis defective || aqueous positive chemotaxis defective || sodium chloride chemotaxis variant || chemosensory response variant || response to food variant || aqueous positive chemotaxis variant || sodium chloride chemotaxis defective || chemotaxis variant |
| Calcium ATPase, transduction domain A | 0.08871 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.08871 | INHERITED FROM: nicotine hypersensitive || drug hypersensitive |
| PDZ domain | 0.08871 | INHERITED FROM: chemical resistant || aldicarb response variant || egg laying serotonin variant |
| SH3-domain | 0.1138 | INHERITED FROM: aldicarb response variant |
| Pleckstrin-homology domain (PH domain) | 0.1138 | INHERITED FROM: diacetyl chemotaxis variant || AWA odorant chemotaxis variant || aldicarb response variant || egg laying imipramine resistant || egg laying serotonin variant |
| Regulator of G-protein signaling, RGS | 0.1213 | INHERITED FROM: negative chemotaxis variant || chemotaxis variant |
| Glutathione peroxidase-like | 0.1303 | INHERITED FROM: paraquat response variant || paraquat hypersensitive || organism toxic chemical response variant |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0.1602 | INHERITED FROM: unfolded protein response variant |
| Meta-cation ATPase, catalytic domain P | 0.1834 | INHERITED FROM: nicotine hypersensitive || nicotine response variant |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.2398 | INHERITED FROM: odorant positive chemotaxis variant || chemical resistant || aldicarb response variant || drug resistant |
| Cytochrome P450 | 0.2432 | INHERITED FROM: cadmium hypersensitive |
| Erythroid transcription factor GATA-1 | 0.2699 | INHERITED FROM: paraquat response variant || organism toxic chemical response variant |
| SNF-like | 0.2699 | INHERITED FROM: drug hypersensitive |
| HMG-box | 0.2699 | INHERITED FROM: anesthetic response variant |
| WD40-repeat | 0.2927 | INHERITED FROM: osmotic avoidance variant || ivermectin response variant || ivermectin resistant |
| Calcium ATPase, transmembrane domain M | 0.3515 | INHERITED FROM: nicotine hypersensitive || drug response variant |
| Voltage-gated potassium channels | 0.4502 | INHERITED FROM: serotonin resistant || serotonin response variant || phentolamine resistant || adrenergic receptor antagonist response variant |
| Group II chaperonin (CCT, TRIC), apical domain | 0.4659 | INHERITED FROM: unfolded protein response variant |
| Bromodomain | 0.4659 | INHERITED FROM: anesthetic response variant || drug adaptation variant || ethanol resistant || anesthetic resistant || acute functional tolerance to alcohol defective |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.4659 | INHERITED FROM: unfolded protein response variant |
| Tubulin, GTPase domain | 0.5641 | INHERITED FROM: nicotine response variant |
| Fatty acid binding protein-like | 0.5995 | INHERITED FROM: paraquat response variant || paraquat hypersensitive || organism toxic chemical response variant |
| DBL homology domain (DH-domain) | 0.6006 | INHERITED FROM: aldicarb response variant |
| Homeodomain | 0.6888 | INHERITED FROM: anesthetic response variant || carbon dioxide avoidance variant || carbon dioxide response variant |
| Leucine zipper domain | 0.7016 | INHERITED FROM: pore forming toxin response variant |
| Tubulin, C-terminal domain | 0.7016 | INHERITED FROM: nicotine response variant |
| Glutathione S-transferase (GST), N-terminal domain | 0.738 | INHERITED FROM: paraquat response variant || chemical hypersensitive || organism toxic chemical response variant |
| HLH, helix-loop-helix DNA-binding domain | 0.8947 | INHERITED FROM: aqueous positive chemotaxis defective || lysine chemotaxis defective |
| Glutathione S-transferase (GST), C-terminal domain | 0.9225 | INHERITED FROM: cadmium hypersensitive |
| Rhodopsin-like | 0.9496 | INHERITED FROM: serotonin resistant || male tail curling serotonin variant || locomotion rate serotonin variant || serotonin induced pumping variant || serotonin response variant || drug withdrawal response variant || aqueous adaptation defective || serotonin induced fat reduction variant || mianserin resistant || cyproheptadine resistant || serotonin hypersensitive || biogenic amine receptor antagonist resistant || methiothepin resistant || egg laying response to drug variant |
| Nuclear receptor | 1 | INHERITED FROM: SDS sensitive dauer |
| Ankyrin repeat | 1 | INHERITED FROM: odorant negative chemotaxis defective || octanol chemotaxis variant || octanol chemotaxis defective |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 1 | INHERITED FROM: paraquat response variant || paraquat resistant || organism toxic chemical response variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Cullin repeat | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Nicotinic receptor ligand binding domain-like | 0.000000001038 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.000000001038 | Direct |
| Skp1 dimerisation domain-like | 0.000000001677 | Direct |
| Protein kinases, catalytic subunit | 0.000001132 | Direct |
| Cullin homology domain | 0.000007587 | Direct |
| Transducin (alpha subunit), insertion domain | 0.00001676 | Direct |
| Adenylyl and guanylyl cyclase catalytic domain | 0.00002047 | Direct |
| cAMP-binding domain | 0.00007263 | Direct |
| ABC transporter transmembrane region | 0.00118 | Inherited |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0.001271 | Inherited |
| H-NOX domain | 0.001493 | Inherited |
| Eps15 homology domain (EH domain) | 0.001493 | Inherited |
| BTB/POZ domain | 0.00547 | Inherited |
| Transforming growth factor (TGF)-beta | 0.00606 | Inherited |
| Cation efflux protein cytoplasmic domain-like | 0.00606 | Inherited |
| PLC-like (P variant) | 0.01166 | Inherited |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.01501 | Inherited |
| t-snare proteins | 0.01519 | Inherited |
| L-arabinose binding protein-like | 0.01619 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.02551 | Inherited |
| G proteins | 0.0261 | Inherited |
| Phosphoribosyltransferases (PRTases) | 0.02925 | Inherited |
| Clathrin coat assembly domain | 0.02925 | Inherited |
| I set domains | 0.03294 | Inherited |
| Synaptotagmin-like (S variant) | 0.03376 | Inherited |
| ABC transporter ATPase domain-like | 0.04774 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.05706 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.05706 | Inherited |
| Spectrin repeat | 0.05706 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.05706 | Inherited |
| Pyridoxal-dependent decarboxylase | 0.05706 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.06154 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.07787 | Inherited |
| Phosphate binding protein-like | 0.07957 | Inherited |
| Calcium ATPase, transduction domain A | 0.08871 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.08871 | Inherited |
| PDZ domain | 0.08871 | Inherited |
| SH3-domain | 0.1138 | Inherited |
| Pleckstrin-homology domain (PH domain) | 0.1138 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1213 | Inherited |
| Glutathione peroxidase-like | 0.1303 | Inherited |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0.1602 | Inherited |
| Meta-cation ATPase, catalytic domain P | 0.1834 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.2398 | Inherited |
| Cytochrome P450 | 0.2432 | Inherited |
| Erythroid transcription factor GATA-1 | 0.2699 | Inherited |
| SNF-like | 0.2699 | Inherited |
| HMG-box | 0.2699 | Inherited |
| WD40-repeat | 0.2927 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.3515 | Inherited |
| Voltage-gated potassium channels | 0.4502 | Inherited |
| Group II chaperonin (CCT, TRIC), apical domain | 0.4659 | Inherited |
| Bromodomain | 0.4659 | Inherited |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.4659 | Inherited |
| Tubulin, GTPase domain | 0.5641 | Inherited |
| Fatty acid binding protein-like | 0.5995 | Inherited |
| DBL homology domain (DH-domain) | 0.6006 | Inherited |
| Homeodomain | 0.6888 | Inherited |
| Leucine zipper domain | 0.7016 | Inherited |
| Tubulin, C-terminal domain | 0.7016 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.738 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.8947 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.9225 | Inherited |
| Rhodopsin-like | 0.9496 | Inherited |
| Nuclear receptor | 1 | Inherited |
| Ankyrin repeat | 1 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
 |
Plot tree as:
| |
Download Newick format tree:
|
(show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0.00000000001744 | DIRECT |
| Nicotinic receptor ligand binding domain-like | 0.0000000003094 | DIRECT |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.0000000005323 | DIRECT |
| Cullin repeat-like | 0.00000004414 | DIRECT |
| Protein kinase-like (PK-like) | 0.0000001311 | DIRECT |
| Cullin homology domain | 0.000002302 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0.00001303 | DIRECT |
| Nucleotide cyclase | 0.00001516 | DIRECT |
| cAMP-binding domain-like | 0.00004114 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.0001695 | DIRECT |
| ABC transporter transmembrane region | 0.0005945 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0006373 | DIRECT |
| Periplasmic binding protein-like I | 0.004716 | INHERITED FROM: bromide chemotaxis variant || carbon dioxide avoidance variant || chemosensory response variant || aqueous positive chemotaxis variant || chemotaxis variant || carbon dioxide response variant || diacetyl chemotaxis variant || iodide chemotaxis variant || magnesium chemotaxis defective || AWC odorant chemotaxis defective || benzaldehyde chemotaxis variant || AWC odorant chemotaxis variant || alkaline pH chemotaxis variant || lithium chemotaxis defective || aqueous chemosensory response variant || bromide chemotaxis defective || iodide chemotaxis defective |
| Cation efflux protein transmembrane domain-like | 0.005733 | INHERITED FROM: cadmium hypersensitive || manganese toxicity resistant || manganese response variant |
| t-snare proteins | 0.007388 | INHERITED FROM: drug hypersensitive |
| Myosin rod fragments | 0.007388 | INHERITED FROM: drug resistant |
| Cation efflux protein cytoplasmic domain-like | 0.008285 | INHERITED FROM: cadmium hypersensitive || chemical hypersensitive |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.008285 | INHERITED FROM: organism toxic chemical response variant || paraquat response variant |
| EF-hand | 0.01491 | INHERITED FROM: aldicarb response variant |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.04142 | INHERITED FROM: drug hypersensitive |
| PRTase-like | 0.04359 | INHERITED FROM: drug resistant || Fluorouracil resistant |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0544 | INHERITED FROM: unfolded protein response variant |
| Lipovitellin-phosvitin complex, superhelical domain | 0.0544 | INHERITED FROM: unfolded protein response variant |
| Spectrin repeat | 0.0544 | INHERITED FROM: aldicarb response variant || drug response variant |
| ENTH/VHS domain | 0.05592 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant |
| TPR-like | 0.0627 | INHERITED FROM: chemotaxis variant || ivermectin resistant || positive chemotaxis defective || ivermectin response variant |
| Voltage-gated potassium channels | 0.07115 | INHERITED FROM: phentolamine resistant || serotonin response variant || imipramine resistant || serotonin resistant || adrenergic receptor antagonist response variant || positive chemotaxis defective |
| Periplasmic binding protein-like II | 0.07457 | INHERITED FROM: response to food variant || chemosensory response variant || aqueous positive chemotaxis variant || chemotaxis variant || sodium chloride chemotaxis defective || sodium chloride chemotaxis variant || positive chemotaxis defective || aqueous positive chemotaxis defective |
| Immunoglobulin | 0.07895 | INHERITED FROM: aldicarb response variant |
| Cytochrome P450 | 0.07895 | INHERITED FROM: cadmium hypersensitive |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.0819 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive |
| Calcium ATPase, transmembrane domain M | 0.0819 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive |
| Calcium ATPase, transduction domain A | 0.0819 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive |
| Troponin coil-coiled subunits | 0.09237 | INHERITED FROM: nicotine response variant || drug response variant |
| SH3-domain | 0.1007 | INHERITED FROM: aldicarb response variant |
| SAM/Pointed domain | 0.1151 | INHERITED FROM: aldicarb response variant |
| Regulator of G-protein signaling, RGS | 0.1151 | INHERITED FROM: negative chemotaxis variant || chemotaxis variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1201 | INHERITED FROM: chemotaxis variant || odorant positive chemotaxis defective || odorant chemosensory response variant || positive chemotaxis defective |
| PDZ domain-like | 0.1249 | INHERITED FROM: chemical resistant || acetylcholinesterase inhibitor response variant || drug resistant || aldicarb response variant |
| WD40 repeat-like | 0.1372 | INHERITED FROM: osmotic avoidance variant || aldicarb response variant |
| Cysteine-rich domain | 0.1543 | INHERITED FROM: odorant positive chemotaxis variant || acetylcholinesterase inhibitor response variant || positive chemotaxis variant || aldicarb response variant || odorant chemosensory response variant |
| PYP-like sensor domain (PAS domain) | 0.1559 | INHERITED FROM: carbon dioxide avoidance variant || carbon dioxide response variant || anesthetic response variant |
| SNARE-like | 0.173 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant |
| PH domain-like | 0.181 | INHERITED FROM: aldicarb response variant |
| EGF/Laminin | 0.2197 | INHERITED FROM: odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant |
| SMAD/FHA domain | 0.2249 | INHERITED FROM: aldicarb response variant |
| Glutathione synthetase ATP-binding domain-like | 0.2249 | INHERITED FROM: negative chemotaxis variant || chemotaxis variant || osmotic avoidance variant |
| "Winged helix" DNA-binding domain | 0.237 | INHERITED FROM: anesthetic response variant |
| HMG-box | 0.2605 | INHERITED FROM: anesthetic response variant |
| SNF-like | 0.2605 | INHERITED FROM: drug hypersensitive |
| HAD-like | 0.2835 | INHERITED FROM: nicotine hypersensitive |
| Cystine-knot cytokines | 0.3167 | INHERITED FROM: levamisole response variant || nicotine response variant |
| P-loop containing nucleoside triphosphate hydrolases | 0.3325 | INHERITED FROM: carbon dioxide avoidance variant || chemotaxis variant || aldicarb response variant || hydroxyurea response variant |
| GroEL equatorial domain-like | 0.3373 | INHERITED FROM: unfolded protein response variant |
| WW domain | 0.3373 | INHERITED FROM: acetylcholinesterase inhibitor resistant || aldicarb resistant |
| GroEL apical domain-like | 0.3373 | INHERITED FROM: unfolded protein response variant |
| GroEL-intermediate domain like | 0.3373 | INHERITED FROM: unfolded protein response variant |
| Lipocalins | 0.3373 | INHERITED FROM: paraquat hypersensitive |
| FAD/NAD(P)-binding domain | 0.3638 | INHERITED FROM: organism toxic chemical response variant |
| Bromodomain | 0.4523 | INHERITED FROM: acute functional tolerance to alcohol defective || drug adaptation variant || anesthetic response variant || anesthetic resistant || ethanol resistant |
| Homeodomain-like | 0.4589 | INHERITED FROM: egg laying imipramine resistant || carbon dioxide avoidance variant || phentolamine resistant || carbon dioxide response variant || imipramine resistant || adrenergic receptor antagonist response variant |
| Cysteine proteinases | 0.4621 | INHERITED FROM: paraquat hypersensitive |
| HSP20-like chaperones | 0.5467 | INHERITED FROM: cadmium hypersensitive |
| Tubulin nucleotide-binding domain-like | 0.5467 | INHERITED FROM: nicotine response variant |
| DBL homology domain (DH-domain) | 0.578 | INHERITED FROM: aldicarb response variant |
| Thioredoxin-like | 0.6269 | INHERITED FROM: organism toxic chemical response variant || paraquat response variant |
| Tubulin C-terminal domain-like | 0.6809 | INHERITED FROM: nicotine response variant |
| Leucine zipper domain | 0.6809 | INHERITED FROM: pore forming toxin response variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8237 | INHERITED FROM: SDS sensitive dauer |
| GST C-terminal domain-like | 0.877 | INHERITED FROM: cadmium hypersensitive |
| HLH, helix-loop-helix DNA-binding domain | 0.8814 | INHERITED FROM: lysine chemotaxis defective || aqueous positive chemotaxis defective |
| Sm-like ribonucleoproteins | 0.9533 | INHERITED FROM: unfolded protein response variant |
| MFS general substrate transporter | 1 | INHERITED FROM: organism high sodium chloride hypersensitive |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer |
| Ankyrin repeat | 1 | INHERITED FROM: odorant negative chemotaxis defective || chemosensory response variant || chemotaxis variant || octanol chemotaxis defective || octanol chemotaxis variant |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: hydroxyurea hypersensitive || hydroxyurea response variant |
| Nucleotidylyl transferase | 1 | INHERITED FROM: paraquat resistant |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: serotonin induced pumping variant || serotonin induced fat reduction variant || male tail curling serotonin variant || locomotion rate serotonin variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: egg laying imipramine resistant || inhibitor of serotonin uptake variant || imipramine resistant || egg laying serotonin resistant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Skp1 dimerisation domain-like | 0.00000000001744 | Direct |
| Nicotinic receptor ligand binding domain-like | 0.0000000003094 | Direct |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.0000000005323 | Direct |
| Cullin repeat-like | 0.00000004414 | Direct |
| Protein kinase-like (PK-like) | 0.0000001311 | Direct |
| Cullin homology domain | 0.000002302 | Direct |
| Transducin (alpha subunit), insertion domain | 0.00001303 | Direct |
| Nucleotide cyclase | 0.00001516 | Direct |
| cAMP-binding domain-like | 0.00004114 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.0001695 | Direct |
| ABC transporter transmembrane region | 0.0005945 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0006373 | Direct |
| Periplasmic binding protein-like I | 0.004716 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.005733 | Inherited |
| t-snare proteins | 0.007388 | Inherited |
| Myosin rod fragments | 0.007388 | Inherited |
| Cation efflux protein cytoplasmic domain-like | 0.008285 | Inherited |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.008285 | Inherited |
| EF-hand | 0.01491 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0.04142 | Inherited |
| PRTase-like | 0.04359 | Inherited |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0544 | Inherited |
| Lipovitellin-phosvitin complex, superhelical domain | 0.0544 | Inherited |
| Spectrin repeat | 0.0544 | Inherited |
| ENTH/VHS domain | 0.05592 | Inherited |
| TPR-like | 0.0627 | Inherited |
| Voltage-gated potassium channels | 0.07115 | Inherited |
| Periplasmic binding protein-like II | 0.07457 | Inherited |
| Immunoglobulin | 0.07895 | Inherited |
| Cytochrome P450 | 0.07895 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.0819 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.0819 | Inherited |
| Calcium ATPase, transduction domain A | 0.0819 | Inherited |
| Troponin coil-coiled subunits | 0.09237 | Inherited |
| SH3-domain | 0.1007 | Inherited |
| SAM/Pointed domain | 0.1151 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1151 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1201 | Inherited |
| PDZ domain-like | 0.1249 | Inherited |
| WD40 repeat-like | 0.1372 | Inherited |
| Cysteine-rich domain | 0.1543 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.1559 | Inherited |
| SNARE-like | 0.173 | Inherited |
| PH domain-like | 0.181 | Inherited |
| EGF/Laminin | 0.2197 | Inherited |
| SMAD/FHA domain | 0.2249 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 0.2249 | Inherited |
| "Winged helix" DNA-binding domain | 0.237 | Inherited |
| HMG-box | 0.2605 | Inherited |
| SNF-like | 0.2605 | Inherited |
| HAD-like | 0.2835 | Inherited |
| Cystine-knot cytokines | 0.3167 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.3325 | Inherited |
| GroEL equatorial domain-like | 0.3373 | Inherited |
| WW domain | 0.3373 | Inherited |
| GroEL apical domain-like | 0.3373 | Inherited |
| GroEL-intermediate domain like | 0.3373 | Inherited |
| Lipocalins | 0.3373 | Inherited |
| FAD/NAD(P)-binding domain | 0.3638 | Inherited |
| Bromodomain | 0.4523 | Inherited |
| Homeodomain-like | 0.4589 | Inherited |
| Cysteine proteinases | 0.4621 | Inherited |
| HSP20-like chaperones | 0.5467 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.5467 | Inherited |
| DBL homology domain (DH-domain) | 0.578 | Inherited |
| Thioredoxin-like | 0.6269 | Inherited |
| Tubulin C-terminal domain-like | 0.6809 | Inherited |
| Leucine zipper domain | 0.6809 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8237 | Inherited |
| GST C-terminal domain-like | 0.877 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.8814 | Inherited |
| Sm-like ribonucleoproteins | 0.9533 | Inherited |
| MFS general substrate transporter | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| Ankyrin repeat | 1 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| Nucleotidylyl transferase | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.0000000005323 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0.0000000006158 | DIRECT |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.0000009828 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00001303 | DIRECT |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0005945 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0.0007896 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0.0008335 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.001189 | INHERITED FROM: chemotaxis variant || ivermectin resistant || aldicarb response variant || aqueous chemosensory response variant || positive chemotaxis defective || ivermectin response variant |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0.001696 | INHERITED FROM: drug response variant |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.008285 | INHERITED FROM: organism toxic chemical response variant || paraquat response variant |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0.008285 | INHERITED FROM: cadmium hypersensitive || chemical hypersensitive |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.009165 | INHERITED FROM: negative chemotaxis variant || aqueous positive chemotaxis variant || chemotaxis variant || ivermectin resistant || chemical resistant || osmotic avoidance variant || drug resistant || positive chemotaxis variant || odorant chemosensory response variant || aqueous chemosensory response variant || positive chemotaxis defective || ivermectin response variant || aqueous positive chemotaxis defective |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.0544 | INHERITED FROM: unfolded protein response variant |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0544 | INHERITED FROM: unfolded protein response variant |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.0544 | INHERITED FROM: acetylcholinesterase inhibitor response variant || aldicarb response variant || drug response variant |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.0819 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0.09237 | INHERITED FROM: drug response variant |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.09237 | INHERITED FROM: chemical resistant || drug resistant |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1201 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0.2605 | INHERITED FROM: chemical resistant || drug resistant || aldicarb response variant || drug response variant |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.3373 | INHERITED FROM: unfolded protein response variant |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.3373 | INHERITED FROM: unfolded protein response variant |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.3956 | INHERITED FROM: aldicarb response variant |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.5467 | INHERITED FROM: nicotine response variant |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.6643 | INHERITED FROM: cadmium hypersensitive |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.7458 | INHERITED FROM: cadmium hypersensitive || paraquat response variant |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.9255 | INHERITED FROM: cadmium hypersensitive |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.0000000005323 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0.0000000006158 | Direct |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.0000009828 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00001303 | Direct |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0005945 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0.0007896 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0.0008335 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.001189 | Inherited |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0.001696 | Inherited |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0.008285 | Inherited |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0.008285 | Inherited |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.009165 | Inherited |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0.0544 | Inherited |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0544 | Inherited |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.0544 | Inherited |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.0819 | Inherited |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0.09237 | Inherited |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.09237 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1201 | Inherited |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0.2605 | Inherited |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0.3373 | Inherited |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.3373 | Inherited |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0.3956 | Inherited |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.5467 | Inherited |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.6643 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.7458 | Inherited |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.9255 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0007896 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0.0008335 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0008335 | DIRECT |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0544 | INHERITED FROM: unfolded protein response variant |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1201 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0.1559 | INHERITED FROM: chemical resistant || drug resistant |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.3373 | INHERITED FROM: unfolded protein response variant |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.4654 | INHERITED FROM: cadmium hypersensitive |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0007896 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0.0008335 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0008335 | Direct |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0.0544 | Inherited |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1201 | Inherited |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0.1559 | Inherited |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.3373 | Inherited |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.4654 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
|
Plot tree as:
| |
Download Newick format tree:
|
(show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
