Worm Phenotype (WP): body region morphology variant

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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)

+ + + 3: Variant [WBPhenotype:0000886] <2>

+ + 2: morphology variant [WBPhenotype:0000520] <5> (443|528) (444|229|63)

+ 1: organism morphology variant [WBPhenotype:0000535] <7> (321|428) (322|184|49)

0: body region morphology variant [WBPhenotype:0000532] <6> (46|48) (47|17|7)

- 1: body morphology variant [WBPhenotype:0000072] <9> (35|42) (36|11|7)

- 1: tail morphology variant [WBPhenotype:0000073] <8> (11|8) (11|2|0)

- 1: head morphology variant [WBPhenotype:0000071] <7> (0|0) (0|0|0)

- 1: body axis morphology variant [WBPhenotype:0000581] <2> (3|3) (3|1|0)

- 1: body region pigmentation variant [WBPhenotype:0000278] <2> (0|0) (0|0|0)

- 1: pseudocoelom morphology variant [WBPhenotype:0000949] (2|0) (2|1|0)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP term	FDR (all)	Annotation (direct or inherited)
Multidrug efflux transporter AcrB transmembrane domain	0	Direct
Skp1 dimerisation domain-like	0	Direct
Transducin (alpha subunit), insertion domain	0	Direct
Homeodomain-like	0.0000000001887	Direct
DBL homology domain (DH-domain)	0.0000000005389	Direct
Insulin-like	0.000000001054	Direct
Hedgehog/intein (Hint) domain	0.0000001177	Direct
Immunoglobulin	0.0000005633	Direct
PH domain-like	0.000005033	Direct
SNF-like	0.00000579	Direct
Lamin A/C globular tail domain	0.00001241	Direct
P-loop containing nucleoside triphosphate hydrolases	0.00002327	Direct
Neurotransmitter-gated ion-channel transmembrane pore	0.00002803	Direct
Intermediate filament protein, coiled coil region	0.0001796	Direct
Spectrin repeat	0.0001796	Direct
Growth factor receptor domain	0.0002122	Direct
Nicotinic receptor ligand binding domain-like	0.0002413	Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	0.0002474	Direct
SMAD MH1 domain	0.0003311	Direct
Nucleotide-binding domain	0.0003311	Direct
Transducin (heterotrimeric G protein), gamma chain	0.0004094	Direct
S-adenosylmethionine synthetase	0.0005184	Direct
Zn-binding ribosomal proteins	0.000747	Direct
cAMP-binding domain-like	0.001241	Inherited
Tim10-like	0.002171	Inherited
Subtilisin-like	0.002171	Inherited
Multidrug resistance efflux transporter EmrE	0.002217	Inherited
Troponin coil-coiled subunits	0.002274	Inherited
SNARE-like	0.00565	Inherited
lambda repressor-like DNA-binding domains	0.01223	Inherited
PYP-like sensor domain (PAS domain)	0.01914	Inherited
Cysteine-rich domain	0.02322	Inherited
Heme-dependent peroxidases	0.026	Inherited
Ankyrin repeat	0.02807	Inherited
Thiamin diphosphate-binding fold (THDP-binding)	0.03	Inherited
Voltage-gated potassium channels	0.04209	Inherited
Cysteine-rich DNA binding domain, (DM domain)	0.06024	Inherited
Protease propeptides/inhibitors	0.06024	Inherited
FYVE/PHD zinc finger	0.07284	Inherited
SMAD/FHA domain	0.08142	Inherited
Histone-fold	0.08883	Inherited
POZ domain	0.3158	Inherited
Protein kinase-like (PK-like)	0.3569	Inherited
Thioredoxin-like	0.8311	Inherited
C-type lectin-like	1	Inherited
GST C-terminal domain-like	1	Inherited

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Family

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SCOP term	FDR (all)	Annotation (direct or inherited)
Multidrug efflux transporter AcrB transmembrane domain	0	Direct
D-aminoacid oxidase, N-terminal domain	0	Direct
Branched-chain alpha-keto acid dehydrogenase PP module	0	Direct
MIF4G domain-like	0	Direct
Skp1 dimerisation domain-like	0	Direct
Transducin (alpha subunit), insertion domain	0.000000000000005317	Direct
Homeodomain	0.0000000003492	Direct
DBL homology domain (DH-domain)	0.000000006293	Direct
Insulin-like	0.00000001555	Direct
G proteins	0.0000001353	Direct
Pleckstrin-homology domain (PH domain)	0.0000003529	Direct
Hedgehog C-terminal (Hog) autoprocessing domain	0.000000529	Direct
SNF-like	0.00001227	Direct
Laminin-type module	0.00001988	Direct
Clathrin coat assembly domain	0.000117	Direct
D-aminoacid oxidase-like	0.0001334	Direct
I set domains	0.0002033	Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	0.0004898	Direct
Intermediate filament protein, coiled coil region	0.0004996	Direct
BTB/POZ domain	0.0005304	Direct
PDI-like	0.0006669	Direct
SMAD MH1 domain	0.0006669	Direct
Transducin (heterotrimeric G protein), gamma chain	0.0006818	Direct
Neurotransmitter-gated ion-channel transmembrane pore	0.0007032	Direct
Nicotinic receptor ligand binding domain-like	0.0008744	Direct
Glycosyl transferases group 1	0.0008786	Direct
Proprotein convertase P-domain	0.0008786	Direct
Troponin I	0.0008786	Direct
S-adenosylmethionine synthetase	0.0008786	Direct
Growth factor receptor domain	0.000896	Direct
Lamin A/C globular tail domain	0.001002	Inherited
Clathrin adaptor core protein	0.001457	Inherited
cAMP-binding domain	0.001891	Inherited
Spectrin repeat	0.002133	Inherited
Transforming growth factor (TGF)-beta	0.003656	Inherited
Tim10/DDP	0.003656	Inherited
Subtilases	0.003656	Inherited
SMAD domain	0.004453	Inherited
CUT domain	0.009233	Inherited
Myeloperoxidase-like	0.0476	Inherited
Cysteine-rich DNA binding domain, (DM domain)	0.09498	Inherited
Synaptotagmin-like (S variant)	0.1045	Inherited
Ankyrin repeat	0.1076	Inherited
Voltage-gated potassium channels	0.137	Inherited
Rhodopsin-like	0.1766	Inherited
Nucleosome core histones	0.259	Inherited
Protein kinases, catalytic subunit	0.7315	Inherited
C-type lectin domain	1	Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term

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Supra-domain (including individual superfamily)

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Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
Skp1 dimerisation domain-like	0	Direct
Transducin (alpha subunit), insertion domain	0	Direct
Multidrug efflux transporter AcrB transmembrane domain	0	Direct
Homeodomain-like	0.0000000001495	Direct
DBL homology domain (DH-domain)	0.0000000004275	Direct
Insulin-like	0.0000000008365	Direct
Hedgehog/intein (Hint) domain	0.00000009428	Direct
Immunoglobulin	0.0000004542	Direct
PH domain-like	0.000004092	Direct
SNF-like	0.000004709	Direct
Lamin A/C globular tail domain	0.0000101	Direct
P-loop containing nucleoside triphosphate hydrolases	0.00001898	Direct
Neurotransmitter-gated ion-channel transmembrane pore	0.00002288	Direct
Intermediate filament protein, coiled coil region	0.0001475	Direct
Spectrin repeat	0.0001475	Direct
Growth factor receptor domain	0.0001744	Direct
Nicotinic receptor ligand binding domain-like	0.0001984	Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	0.0002034	Direct
Nucleotide-binding domain	0.0002729	Direct
SMAD MH1 domain	0.0002729	Direct
Transducin (heterotrimeric G protein), gamma chain	0.0003379	Direct
S-adenosylmethionine synthetase	0.000429	Direct
Zn-binding ribosomal proteins	0.0006206	Direct
cAMP-binding domain-like	0.001035	Inherited
EGF/Laminin	0.001481	Inherited
Tim10-like	0.001824	Inherited
Subtilisin-like	0.001824	Inherited
Multidrug resistance efflux transporter EmrE	0.001863	Inherited
Troponin coil-coiled subunits	0.001912	Inherited
SNARE-like	0.004807	Inherited
lambda repressor-like DNA-binding domains	0.01055	Inherited
PYP-like sensor domain (PAS domain)	0.01664	Inherited
Cysteine-rich domain	0.02027	Inherited
Heme-dependent peroxidases	0.02276	Inherited
Ankyrin repeat	0.02462	Inherited
Thiamin diphosphate-binding fold (THDP-binding)	0.02634	Inherited
Voltage-gated potassium channels	0.03715	Inherited
Cysteine-rich DNA binding domain, (DM domain)	0.05364	Inherited
Protease propeptides/inhibitors	0.05364	Inherited
FYVE/PHD zinc finger	0.06516	Inherited
SMAD/FHA domain	0.07308	Inherited
Histone-fold	0.07991	Inherited
POZ domain	0.2964	Inherited
Protein kinase-like (PK-like)	0.3366	Inherited
Thioredoxin-like	0.8133	Inherited
GST C-terminal domain-like	1	Inherited
C-type lectin-like	1	Inherited

(show details)

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
51971,54373 51971 - Nucleotide-binding domain 54373 - FAD-linked reductases, C-terminal domain	0	Direct
54695,81382 54695 - POZ domain 81382 - Skp1 dimerisation domain-like	0	Direct
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases	0	Direct
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like	0.000000008859	Direct
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin	0.000004786	Direct
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin	0.00001889	Direct
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore	0.00002288	Direct
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C	0.0003379	Direct
55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase	0.000429	Direct
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like	0.000429	Direct
64356,49447 64356 - SNARE-like 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	0.000429	Direct
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III	0.0006851	Direct
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like	0.0007133	Direct
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat	0.0008264	Direct
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like	0.004239	Inherited
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like	0.006559	Inherited
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like	1	Inherited

(show details)

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin	0.000114	Direct
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin	0.0002338	Direct
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat	0.0002729	Direct
55973,55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase	0.000429	Direct
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III	0.0007712	Direct
52833,52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like 52833 - Thioredoxin-like	0.001482	Inherited
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module	0.05364	Inherited

Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term

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Worm Phenotype (WP): body region morphology variant

Superfamily

Family

Supra-domain (including individual superfamily)