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Worm Phenotype (WP): organism homeostasis metabolism variant
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Doublecortin (DC) | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| PH domain-like | 0.00001282 | DIRECT |
| PDZ domain-like | 0.007203 | INHERITED FROM: protein expression variant || drug resistant || acetylcholinesterase inhibitor response variant || chemical resistant || aldicarb response variant |
| TPR-like | 0.009752 | INHERITED FROM: light body touch resistant || positive chemotaxis defective || antihelmintic response variant || ivermectin resistant || chemotaxis variant || ivermectin response variant |
| ARM repeat | 0.01392 | INHERITED FROM: gene expression variant || protein expression variant || sick || organism metabolism processing variant || RNAi response variant |
| ABC transporter transmembrane region | 0.01722 | INHERITED FROM: cadmium response variant || chemical hypersensitive || chemical response variant || colchicine hypersensitive || RNAi resistant || metal response variant || cadmium hypersensitive || RNAi response variant |
| SH3-domain | 0.03991 | INHERITED FROM: protein expression variant || protein phosphorylation variant || protein expression reduced || aldicarb response variant || protein metabolism variant |
| Homeodomain-like | 0.04118 | INHERITED FROM: growth rate variant || egg laying imipramine resistant || adrenergic receptor antagonist response variant || phentolamine resistant || carbon dioxide response variant || level of transgene expression variant || protein degradation variant || ectopic expression transgene || carbon dioxide avoidance variant || imipramine resistant || organism metabolism processing variant |
| WD40 repeat-like | 0.04816 | INHERITED FROM: osmotic avoidance variant || pathogen induced antimicrobial gene expression variant || protein aggregation induced behavior variant || early larval arrest || aldicarb response variant || late larval arrest || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| CCCH zinc finger | 0.06231 | INHERITED FROM: gene expression variant || transgene expression variant || mRNA expression ectopic || ectopic expression transgene |
| Translation proteins | 0.07835 | INHERITED FROM: mRNA levels increased || gene expression variant || transgene expression variant || protein phosphorylation variant || proteasome core activity variant || protein phosphorylation increased || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| "Winged helix" DNA-binding domain | 0.07882 | INHERITED FROM: spontaneous mutation rate increased || protein expression increased || germline transgene silencing variant || anesthetic response variant || protein aggregation induced behavior variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| HLH, helix-loop-helix DNA-binding domain | 0.08967 | INHERITED FROM: pathogen resistance increased || hypoxia response variant || ectopic expression transgene || RNA expression variant || gene expression level reduced || aqueous positive chemotaxis defective || fungal resistance increased || organism metabolism processing variant || lysine chemotaxis defective |
| SMAD/FHA domain | 0.09815 | INHERITED FROM: fat content reduced |
| Calcium ATPase, transmembrane domain M | 0.11 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive || lipid composition variant |
| EGF/Laminin | 0.1181 | INHERITED FROM: odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1233 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive || lipid composition variant |
| Regulator of G-protein signaling, RGS | 0.1233 | INHERITED FROM: negative chemotaxis variant || chemotaxis variant || mechanosensation variant |
| Acid proteases | 0.138 | INHERITED FROM: gene expression variant || hypoosmotic shock hypersensitive || transgene expression variant || osmotic integrity variant || transgene subcellular localization variant || protein interaction variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Calcium ATPase, transduction domain A | 0.138 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
| Cysteine-rich domain | 0.1423 | INHERITED FROM: gene expression variant || pathogen induced antimicrobial gene expression variant || positive chemotaxis variant || protein subcellular localization variant || thermosensory behavior variant || organism stress response variant || pathogen induced gene expression variant || drug induced gene expression variant || acetylcholinesterase inhibitor response variant || thermotaxis variant || response to injury variant || odorant positive chemotaxis variant || odorant chemosensory response variant || antimicrobial gene expression variant || aldicarb response variant || bacterially unswollen || organism metabolism processing variant |
| Quinoprotein alcohol dehydrogenase-like | 0.1541 | INHERITED FROM: mRNA levels increased || protein degradation variant || hypoxia response variant || mid larval arrest || L2 arrest |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1557 | INHERITED FROM: positive chemotaxis defective || embryo osmotic integrity defective early emb || chemotaxis variant || egg integrity defective early emb || odorant chemosensory response variant || odorant positive chemotaxis defective |
| Cytochrome P450 | 0.16 | INHERITED FROM: cadmium response variant || metabolite content decreased || metal response variant || cadmium hypersensitive |
| (Trans)glycosidases | 0.1699 | INHERITED FROM: pathogen susceptibility increased |
| P-loop containing nucleoside triphosphate hydrolases | 0.1716 | INHERITED FROM: spontaneous mutation rate increased || organism environmental stimulus response variant || organism UV response variant || chemotaxis variant || organism hypersensitive ionizing radiation || sick || carbon dioxide avoidance variant || RNAi resistant || pathogen release variant || aldicarb response variant || pattern of transgene expression variant || organism metabolism processing variant || RNAi response variant |
| ClpP/crotonase | 0.1722 | INHERITED FROM: lipid metabolism variant || level of transgene expression variant || fat content variant |
| DBL homology domain (DH-domain) | 0.1722 | INHERITED FROM: pathogen resistance increased || organism environmental stimulus response variant || response to bacteria variant || aldicarb response variant || bacterially unswollen || organism pathogen response variant |
| HMG-box | 0.1722 | INHERITED FROM: transgene expression variant || maintenance of gene silencing variant || anesthetic response variant |
| Ankyrin repeat | 0.1826 | INHERITED FROM: organism heat response variant || chemosensory response variant || chemotaxis variant || odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant |
| Cysteine proteinases | 0.2142 | INHERITED FROM: hypoosmotic shock hypersensitive || osmotic integrity variant || paraquat hypersensitive || protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| POZ domain | 0.22 | INHERITED FROM: L1 arrest || resistant to protein aggregation induced paralysis || protein aggregation induced behavior variant || early larval arrest |
| Cyclin-like | 0.2211 | INHERITED FROM: protein phosphorylation variant || protein phosphorylation reduced |
| Tudor/PWWP/MBT | 0.2397 | INHERITED FROM: pattern of transgene expression variant |
| Bromodomain | 0.2397 | INHERITED FROM: gene expression variant || anesthetic resistant || organism UV response variant || acute functional tolerance to alcohol defective || sick || ethanol resistant || drug adaptation variant || organism UV hypersensitive || anesthetic response variant || organism metabolism processing variant |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2397 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Metallo-dependent phosphatases | 0.2531 | INHERITED FROM: radiation induced germ cell apoptosis variant || germ cell resistant ionizing radiation |
| RNA-binding domain, RBD | 0.2567 | INHERITED FROM: starvation induced apoptosis variant || pathogen induced antimicrobial gene expression variant || no induction of antimicrobial peptide expression after infection || mRNA export variant || innate immune response variant || sick || RNA metabolism variant || RNA processing variant || maintenance of gene silencing variant || RNA expression variant || organism metabolism processing variant || alternative splicing variant |
| Lipocalins | 0.261 | INHERITED FROM: lipid metabolism variant || paraquat hypersensitive || fat content increased || fat content variant |
| SNARE-like | 0.2667 | INHERITED FROM: acetylcholinesterase inhibitor resistant || gene expression variant || transgene expression variant || transgene subcellular localization variant || sick || pattern of transgene expression variant || organism metabolism processing variant || aldicarb resistant |
| PX domain | 0.3312 | INHERITED FROM: protein subcellular localization variant || protein expression variant || protein expression reduced |
| Cation efflux protein transmembrane domain-like | 0.3312 | INHERITED FROM: metal response variant || manganese toxicity resistant || cadmium hypersensitive || manganese response variant |
| Nicotinic receptor ligand binding domain-like | 0.3365 | INHERITED FROM: nicotine resistant || cholinergic agonist resistant || DMPP response variant || hypoosmotic shock hypersensitive || selenium response variant || positive chemotaxis variant || slowing response on food variant || antihelmintic response variant || DMPP resistant || thermosensory behavior variant || drug response variant || organism environmental stimulus response variant || benzaldehyde chemotaxis variant || sodium chloride chemotaxis variant || chemosensory response variant || chemical response variant || thermotaxis variant || chemical resistant || AWC odorant chemotaxis variant || mechanosensation variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3762 | INHERITED FROM: nicotine resistant || cholinergic agonist resistant || DMPP response variant || hypoosmotic shock hypersensitive || selenium response variant || positive chemotaxis variant || slowing response on food variant || antihelmintic response variant || DMPP resistant || thermosensory behavior variant || drug response variant || organism environmental stimulus response variant || benzaldehyde chemotaxis variant || sodium chloride chemotaxis variant || chemosensory response variant || chemical response variant || thermotaxis variant || chemical resistant || AWC odorant chemotaxis variant || mechanosensation variant |
| RNI-like | 0.392 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| FKBP-like | 0.4076 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || protein protein interaction variant || protein aggregation variant |
| HD-domain/PDEase-like | 0.4076 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant || organism temperature response variant |
| Class II aaRS and biotin synthetases | 0.4184 | INHERITED FROM: gene expression variant || transgene expression variant || organism environmental stimulus response variant || oxygen response variant || hypoxia response variant || hypoxia resistant || response to bacteria variant || organism metabolism processing variant || avoids bacterial lawn |
| Hect, E3 ligase catalytic domain | 0.4519 | INHERITED FROM: germ cell ionizing radiation response variant || gene expression variant || transgene expression variant || transgene subcellular localization variant || cell ionizing radiation response variant || protein aggregation induced behavior variant || protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| DHS-like NAD/FAD-binding domain | 0.4519 | INHERITED FROM: metabolic pathway variant || protein acetylation variant |
| Myosin rod fragments | 0.4519 | INHERITED FROM: drug resistant |
| PRTase-like | 0.4519 | INHERITED FROM: Fluorouracil resistant || drug resistant |
| Galactose-binding domain-like | 0.4721 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| SH2 domain | 0.4733 | INHERITED FROM: protein expression variant || protein expression reduced || level of protein expression variant |
| Cystine-knot cytokines | 0.484 | INHERITED FROM: nicotine response variant || levamisole response variant |
| Sm-like ribonucleoproteins | 0.484 | INHERITED FROM: organism heat response variant || protein subcellular localization variant || transgene expression variant || sick || response to bacteria variant || pattern of transgene expression variant || unfolded protein response variant || avoids bacterial lawn |
| Voltage-gated potassium channels | 0.4979 | INHERITED FROM: positive chemotaxis defective || growth rate variant || adrenergic receptor antagonist response variant || phentolamine resistant || protein degradation variant || serotonin resistant || serotonin response variant || imipramine resistant || mechanosensation variant |
| Calpain large subunit, middle domain (domain III) | 0.5007 | INHERITED FROM: metabolic pathway variant || protein degradation variant || protein metabolism variant |
| Riboflavin synthase domain-like | 0.5007 | INHERITED FROM: pattern protein expression variant |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5007 | INHERITED FROM: pattern protein expression variant |
| WW domain | 0.5183 | INHERITED FROM: maintenance of gene silencing variant || aldicarb resistant |
| UBC-like | 0.5201 | INHERITED FROM: transgene subcellular localization variant || sick || protein interaction variant || late larval arrest || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| SAM/Pointed domain | 0.5213 | INHERITED FROM: gene expression level reduced || aldicarb response variant |
| Protein kinase-like (PK-like) | 0.5257 | INHERITED FROM: kinase activity reduced || positive chemotaxis variant || protein subcellular localization variant || metabolic pathway variant || copper hypersensitive || colchicine resistant || protein expression variant || organism environmental stimulus response variant || conflicting sensory integration variant || drug induced gene expression variant || anoxia resistant || chemical response variant || protein phosphorylation variant || transgene expression reduced || hypoxia response variant || lipid synthesis increased || mid larval arrest || alkaline pH chemotaxis variant || protein modification variant || second messenger mediated signaling variant || aqueous chemosensory response variant || egg laying response to food variant || octanol chemotaxis defective || metal response variant || protein phosphorylation reduced || aldicarb response variant || organism osmotic stress hypersensitive || mechanosensation variant || organism oxidative stress response variant |
| Seven-hairpin glycosidases | 0.5556 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
| Multidrug resistance efflux transporter EmrE | 0.557 | INHERITED FROM: pathogen resistance increased || response to bacteria variant || bacterially unswollen |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.577 | INHERITED FROM: cell stress response variant || pathogen induced antimicrobial gene expression variant || protein subcellular localization variant || protein expression variant || organism environmental stimulus response variant || growth rate variant || drug induced gene expression variant || drug resistant || chemical response variant || response to injury variant || chemical resistant || organism osmotic stress response variant || cellular osmotic stress response variant || RNAi response variant |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.608 | INHERITED FROM: organism gamma ray response variant || gamma ray induced apoptosis increased || cell gamma ray response variant |
| KA1-like | 0.6117 | INHERITED FROM: RNA expression variant |
| Di-copper centre-containing domain | 0.6117 | INHERITED FROM: germ cell ionizing radiation response variant || cell stress response variant || organism ionizing radiation response variant || cell ionizing radiation response variant |
| HIT/MYND zinc finger-like | 0.6321 | INHERITED FROM: pattern of transgene expression variant |
| GST C-terminal domain-like | 0.6586 | INHERITED FROM: enzyme activity reduced || organism environmental stimulus response variant || organism stress response variant || enzyme activity variant || organism heat hypersensitive || metal response variant || cadmium hypersensitive || organism electrophilic stress hypersensitive |
| 4Fe-4S ferredoxins | 0.6771 | INHERITED FROM: transgene expression increased |
| S15/NS1 RNA-binding domain | 0.6771 | INHERITED FROM: transgene expression increased || response to bacteria variant || avoids bacterial lawn |
| Frizzled cysteine-rich domain | 0.6771 | INHERITED FROM: transgene expression reduced || antibody staining variant |
| alpha/beta-Hydrolases | 0.6971 | INHERITED FROM: acetylcholinesterase activity variant || acetylcholinesterase reduced |
| ADC-like | 0.7478 | INHERITED FROM: metabolic pathway variant || transgene expression reduced || protein interaction variant || protein metabolism variant || protein protein interaction variant || protein aggregation variant |
| MIT domain | 0.7478 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Clavaminate synthase-like | 0.7901 | INHERITED FROM: protein methylation variant || histone methylation variant |
| NAD kinase/diacylglycerol kinase-like | 0.8023 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant |
| CoA-dependent acyltransferases | 0.8082 | INHERITED FROM: organism metabolism processing variant |
| Cyclophilin-like | 0.8082 | INHERITED FROM: gene expression variant || transgene expression variant || transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || protein protein interaction variant || protein aggregation variant |
| EF-hand | 0.8236 | INHERITED FROM: aldicarb response variant || protein interaction variant || cellular osmotic stress response variant || protein aggregation variant |
| SNF-like | 0.8388 | INHERITED FROM: drug hypersensitive |
| Leucine zipper domain | 0.8422 | INHERITED FROM: mRNA levels reduced || pathogen susceptibility increased || level of transgene expression variant || pore forming toxin response variant || transgene expression reduced || mRNA expression variant |
| GTPase activation domain, GAP | 0.8485 | INHERITED FROM: protein expression variant |
| Eukaryotic type KH-domain (KH-domain type I) | 0.8485 | INHERITED FROM: RNA expression variant |
| Ubiquitin-like | 0.8489 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Thioredoxin-like | 0.8606 | INHERITED FROM: enzyme activity reduced || organism stress response variant || enzyme activity variant || organism heat hypersensitive || organism toxic chemical response variant || paraquat response variant || metal response variant || organism electrophilic stress hypersensitive |
| Ribonuclease H-like | 0.8829 | INHERITED FROM: siRNA expression variant || RNAi enhanced || maintenance of gene silencing variant || RNA expression variant || 21U RNA expression variant || somatic transgene silencing variant || RNAi response variant |
| Immunoglobulin | 0.8882 | INHERITED FROM: growth rate variant || protein degradation variant || aldicarb response variant |
| p53-like transcription factors | 0.8914 | INHERITED FROM: ectopic expression transgene || gene expression level reduced |
| Nucleic acid-binding proteins | 0.8959 | INHERITED FROM: organism environmental stimulus response variant || nonsense mRNA accumulation || hydroxyurea hypersensitive || sick || hydroxyurea response variant || mRNA surveillance defective || hypoxia resistant || avoids bacterial lawn |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9018 | INHERITED FROM: SDS sensitive dauer || fat content increased || level of transgene expression variant || transgene expression reduced || gene expression level reduced || gene expression level high |
| MFS general substrate transporter | 0.9102 | INHERITED FROM: organism high sodium chloride hypersensitive |
| FYVE/PHD zinc finger | 0.9153 | INHERITED FROM: gene expression variant || protein methylation variant || organism UV response variant || organism UV hypersensitive || protein modification variant || organism metabolism processing variant |
| Nucleotide-diphospho-sugar transferases | 0.9173 | INHERITED FROM: lectin response variant || resistant to lectin |
| HAD-like | 0.924 | INHERITED FROM: nicotine hypersensitive |
| Ribonuclease PH domain 2-like | 0.9265 | INHERITED FROM: early larval arrest |
| Saposin | 0.9479 | INHERITED FROM: germ cell ionizing radiation response variant || radiation induced germ cell apoptosis variant || level of transgene expression variant || transgene expression reduced || germ cell resistant ionizing radiation || increased pathogen survival || pathogen load variant |
| FAD/NAD(P)-binding domain | 0.9495 | INHERITED FROM: ATP levels reduced || organism toxic chemical response variant || pesticide response variant || ATP levels variant || organism oxidative stress response variant |
| Periplasmic binding protein-like I | 0.9495 | INHERITED FROM: diacetyl chemotaxis variant || lithium chemotaxis defective || magnesium chemotaxis defective || thermosensory behavior variant || organism environmental stimulus response variant || bromide chemotaxis variant || iodide chemotaxis defective || benzaldehyde chemotaxis variant || chemosensory response variant || chemotaxis variant || iodide chemotaxis variant || carbon dioxide response variant || thermotaxis variant || alkaline pH chemotaxis variant || memory retention defective || bromide chemotaxis defective || second messenger mediated signaling variant || aqueous chemosensory response variant || aqueous positive chemotaxis variant || carbon dioxide avoidance variant || AWC odorant chemotaxis variant || AWC odorant chemotaxis defective || organism temperature response variant || mechanosensation variant |
| PLP-dependent transferases | 0.9559 | INHERITED FROM: radiation induced germ cell apoptosis variant || germ cell resistant ionizing radiation |
| Nucleotide cyclase | 0.9619 | INHERITED FROM: osmotic avoidance variant || diacetyl chemotaxis variant || anion positive chemotaxis variant || anion positive chemotaxis defective || lithium chemotaxis defective || positive chemotaxis variant || magnesium chemotaxis defective || organism environmental stimulus response variant || bromide chemotaxis variant || iodide chemotaxis defective || chemosensory response variant || chemotaxis variant || iodide chemotaxis variant || carbon dioxide response variant || chemical response variant || thermotaxis variant || alkaline pH chemotaxis variant || anesthetic response variant || bromide chemotaxis defective || cation positive chemotaxis variant || second messenger mediated signaling variant || aqueous chemosensory response variant || cation positive chemotaxis defective || AWC odorant chemotaxis variant || AWC odorant chemotaxis defective |
| Ribosomal protein S5 domain 2-like | 0.9704 | INHERITED FROM: early larval arrest |
| SET domain | 0.9772 | INHERITED FROM: gene expression variant || spontaneous mutation rate increased || dosage compensation variant || protein methylation variant || ectopic expression antibody || maintenance of gene silencing variant || protein modification variant || histone methylation variant || pattern of transgene expression variant || organism metabolism processing variant || protein metabolism variant || RNAi response variant |
| PAZ domain | 0.9837 | INHERITED FROM: mRNA levels increased || siRNA expression variant || RNAi enhanced || maintenance of gene silencing variant || RNA expression variant || 21U RNA expression variant || somatic transgene silencing variant || RNAi response variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.9971 | INHERITED FROM: drug response variant || carbon dioxide response variant || chemical response variant || anesthetic response variant || carbon dioxide avoidance variant |
| Snake toxin-like | 1 | INHERITED FROM: fat content reduced |
| PapD-like | 1 | INHERITED FROM: lipid metabolism variant || larval arrest || slow growth || larval growth variant || developmental growth variant || fat content variant |
| RING/U-box | 1 | INHERITED FROM: germ cell ionizing radiation response variant || gene expression variant || cell stress response variant || transgene subcellular localization variant || germ cell hypersensitive ionizing radiation || organism ionizing radiation response variant || cell ionizing radiation response variant || protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Acyl-CoA dehydrogenase C-terminal domain-like | 1 | INHERITED FROM: ascaroside biosynthesis variant || lipid metabolism variant || ascaroside biosynthesis defective || organism metabolism processing variant |
| Translation proteins SH3-like domain | 1 | INHERITED FROM: gene expression variant || transgene expression variant || organism environmental stimulus response variant || early larval arrest || response to bacteria variant || organism metabolism processing variant || avoids bacterial lawn |
| DNA/RNA polymerases | 1 | INHERITED FROM: organism UV response variant || organism UV hypersensitive || DNA metabolism variant |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: egg laying imipramine resistant || inhibitor of serotonin uptake variant || imipramine resistant || organism metabolism processing variant |
| dsRNA-binding domain-like | 1 | INHERITED FROM: maintenance of gene silencing variant || RNA expression variant |
| Nucleotidylyl transferase | 1 | INHERITED FROM: organism environmental stimulus response variant || oxygen response variant || transgene expression increased || paraquat resistant || hypoxia response variant || hypoxia resistant || response to bacteria variant || organism metabolism processing variant || avoids bacterial lawn |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: locomotion rate serotonin variant || male tail curling serotonin variant || serotonin induced pumping variant || serotonin induced fat reduction variant |
| Insulin-like | 1 | INHERITED FROM: temperature induced dauer formation variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: gene expression variant || transgene expression variant || transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Acyl-CoA dehydrogenase NM domain-like | 1 | INHERITED FROM: ascaroside biosynthesis variant || lipid metabolism variant || ascaroside biosynthesis defective || organism metabolism processing variant |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer || fat content increased || level of transgene expression variant || transgene expression reduced || gene expression level reduced || gene expression level high |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| UBA-like | 1 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Doublecortin (DC) | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| FF domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| ARID-like | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Aldolase | 0 | Direct |
| HCP-like | 0 | Direct |
| DEATH domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Tim10-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| WWE domain | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Pentein | 0 | Direct |
| Elafin-like | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| ALDH-like | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| GroES-like | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| MIR domain | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| LEM domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| YWTD domain | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| CBD9-like | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| SIS domain | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| ACP-like | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Polo-box domain | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| GYF domain | 0 | Direct |
| Histone-fold | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| LysM domain | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Cadherin-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| ISP domain | 0 | Direct |
| Nop domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| SAND domain-like | 0 | Direct |
| PGBD-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| TGS-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| L30e-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Integrin domains | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| YbiA-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| PH domain-like | 0.00001282 | Direct |
| PDZ domain-like | 0.007203 | Inherited |
| TPR-like | 0.009752 | Inherited |
| ARM repeat | 0.01392 | Inherited |
| ABC transporter transmembrane region | 0.01722 | Inherited |
| SH3-domain | 0.03991 | Inherited |
| Homeodomain-like | 0.04118 | Inherited |
| WD40 repeat-like | 0.04816 | Inherited |
| CCCH zinc finger | 0.06231 | Inherited |
| Translation proteins | 0.07835 | Inherited |
| "Winged helix" DNA-binding domain | 0.07882 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.08967 | Inherited |
| SMAD/FHA domain | 0.09815 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.11 | Inherited |
| EGF/Laminin | 0.1181 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1233 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1233 | Inherited |
| Acid proteases | 0.138 | Inherited |
| Calcium ATPase, transduction domain A | 0.138 | Inherited |
| Cysteine-rich domain | 0.1423 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1541 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1557 | Inherited |
| Cytochrome P450 | 0.16 | Inherited |
| (Trans)glycosidases | 0.1699 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.1716 | Inherited |
| ClpP/crotonase | 0.1722 | Inherited |
| DBL homology domain (DH-domain) | 0.1722 | Inherited |
| HMG-box | 0.1722 | Inherited |
| Ankyrin repeat | 0.1826 | Inherited |
| Cysteine proteinases | 0.2142 | Inherited |
| POZ domain | 0.22 | Inherited |
| Cyclin-like | 0.2211 | Inherited |
| Tudor/PWWP/MBT | 0.2397 | Inherited |
| Bromodomain | 0.2397 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2397 | Inherited |
| Metallo-dependent phosphatases | 0.2531 | Inherited |
| RNA-binding domain, RBD | 0.2567 | Inherited |
| Lipocalins | 0.261 | Inherited |
| SNARE-like | 0.2667 | Inherited |
| PX domain | 0.3312 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.3312 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.3365 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3762 | Inherited |
| RNI-like | 0.392 | Inherited |
| FKBP-like | 0.4076 | Inherited |
| HD-domain/PDEase-like | 0.4076 | Inherited |
| Class II aaRS and biotin synthetases | 0.4184 | Inherited |
| Hect, E3 ligase catalytic domain | 0.4519 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.4519 | Inherited |
| Myosin rod fragments | 0.4519 | Inherited |
| PRTase-like | 0.4519 | Inherited |
| Galactose-binding domain-like | 0.4721 | Inherited |
| SH2 domain | 0.4733 | Inherited |
| Cystine-knot cytokines | 0.484 | Inherited |
| Sm-like ribonucleoproteins | 0.484 | Inherited |
| Voltage-gated potassium channels | 0.4979 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.5007 | Inherited |
| Riboflavin synthase domain-like | 0.5007 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.5007 | Inherited |
| WW domain | 0.5183 | Inherited |
| UBC-like | 0.5201 | Inherited |
| SAM/Pointed domain | 0.5213 | Inherited |
| Protein kinase-like (PK-like) | 0.5257 | Inherited |
| Seven-hairpin glycosidases | 0.5556 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.557 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.577 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.608 | Inherited |
| KA1-like | 0.6117 | Inherited |
| Di-copper centre-containing domain | 0.6117 | Inherited |
| HIT/MYND zinc finger-like | 0.6321 | Inherited |
| GST C-terminal domain-like | 0.6586 | Inherited |
| 4Fe-4S ferredoxins | 0.6771 | Inherited |
| S15/NS1 RNA-binding domain | 0.6771 | Inherited |
| Frizzled cysteine-rich domain | 0.6771 | Inherited |
| alpha/beta-Hydrolases | 0.6971 | Inherited |
| ADC-like | 0.7478 | Inherited |
| MIT domain | 0.7478 | Inherited |
| Clavaminate synthase-like | 0.7901 | Inherited |
| NAD kinase/diacylglycerol kinase-like | 0.8023 | Inherited |
| CoA-dependent acyltransferases | 0.8082 | Inherited |
| Cyclophilin-like | 0.8082 | Inherited |
| EF-hand | 0.8236 | Inherited |
| SNF-like | 0.8388 | Inherited |
| Leucine zipper domain | 0.8422 | Inherited |
| GTPase activation domain, GAP | 0.8485 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 0.8485 | Inherited |
| Ubiquitin-like | 0.8489 | Inherited |
| Thioredoxin-like | 0.8606 | Inherited |
| Ribonuclease H-like | 0.8829 | Inherited |
| Immunoglobulin | 0.8882 | Inherited |
| p53-like transcription factors | 0.8914 | Inherited |
| Nucleic acid-binding proteins | 0.8959 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.9018 | Inherited |
| MFS general substrate transporter | 0.9102 | Inherited |
| FYVE/PHD zinc finger | 0.9153 | Inherited |
| Nucleotide-diphospho-sugar transferases | 0.9173 | Inherited |
| HAD-like | 0.924 | Inherited |
| Ribonuclease PH domain 2-like | 0.9265 | Inherited |
| Saposin | 0.9479 | Inherited |
| FAD/NAD(P)-binding domain | 0.9495 | Inherited |
| Periplasmic binding protein-like I | 0.9495 | Inherited |
| PLP-dependent transferases | 0.9559 | Inherited |
| Nucleotide cyclase | 0.9619 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.9704 | Inherited |
| SET domain | 0.9772 | Inherited |
| PAZ domain | 0.9837 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.9971 | Inherited |
| Snake toxin-like | 1 | Inherited |
| PapD-like | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| Acyl-CoA dehydrogenase C-terminal domain-like | 1 | Inherited |
| Translation proteins SH3-like domain | 1 | Inherited |
| DNA/RNA polymerases | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| dsRNA-binding domain-like | 1 | Inherited |
| Nucleotidylyl transferase | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Acyl-CoA dehydrogenase NM domain-like | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| UBA-like | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this WP term (Not in SDWP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Chitinase insertion domain | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Internalin LRR domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| PEP carboxykinase C-terminal domain | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| La domain | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Brix domain | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
| Nucleosome core histones | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| Heme-dependent catalases | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| CUT domain | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Fatty acid binding protein-like | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| Tubulin, GTPase domain | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| TBP-associated factors, TAFs | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| 28-residue LRR | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| HSP20 | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Tetraspanin | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| Vertebrate phospholipase A2 | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| GAS2 domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| D-aminoacid oxidase, N-terminal domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| Acireductone dioxygenase | 0 | DIRECT |
| PhzC/PhzF-like | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Cadherin | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| MFPT repeat | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| PDZ domain | 0 | DIRECT |
| Acyl-CoA thioesterase | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| Mammalian PLC | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| CoA transferase alpha subunit-like | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| LacY-like proton/sugar symporter | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| AMPK-beta glycogen binding domain-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| YihX-like | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| Tubulin, C-terminal domain | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| CoA-binding domain | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| PaaI/YdiI-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| SAND domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Arfaptin, Rac-binding fragment | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0.002575 | INHERITED FROM: cell stress response variant || organism stress response variant || organism UV response variant || sick || germline RNAi resistant || RNAi response variant |
| ABC transporter ATPase domain-like | 0.007482 | INHERITED FROM: cadmium response variant || chemical hypersensitive || colchicine hypersensitive || RNAi resistant || metal response variant || cadmium hypersensitive || RNAi response variant |
| Homeodomain | 0.02783 | INHERITED FROM: carbon dioxide response variant || level of transgene expression variant || ectopic expression transgene || anesthetic response variant || carbon dioxide avoidance variant || organism metabolism processing variant |
| G proteins | 0.03312 | INHERITED FROM: protein subcellular localization variant || osmotic integrity variant || drug response variant || organism environmental stimulus response variant || drug induced gene expression variant || chemosensory response variant || chemotaxis variant || protein phosphorylation variant || fat content variant || anesthetic response variant || carbon dioxide avoidance variant || pathogen release variant || aldicarb response variant || organism metabolism processing variant || protein metabolism variant || cellular osmotic stress response variant |
| WD40-repeat | 0.03433 | INHERITED FROM: osmotic avoidance variant || pathogen induced antimicrobial gene expression variant || ivermectin resistant || protein aggregation induced behavior variant || ivermectin response variant |
| ABC transporter transmembrane region | 0.03603 | INHERITED FROM: cadmium response variant || chemical hypersensitive || colchicine hypersensitive || RNAi resistant || metal response variant || cadmium hypersensitive || RNAi response variant |
| SH3-domain | 0.06044 | INHERITED FROM: protein expression variant || protein expression reduced || aldicarb response variant |
| CCCH zinc finger | 0.07548 | INHERITED FROM: gene expression variant || transgene expression variant || mRNA expression ectopic || ectopic expression transgene |
| Canonical RBD | 0.07909 | INHERITED FROM: starvation induced apoptosis variant || pathogen induced antimicrobial gene expression variant || no induction of antimicrobial peptide expression after infection || mRNA export variant || innate immune response variant || sick || RNA metabolism variant || RNA processing variant || RNA expression variant || late larval arrest || organism metabolism processing variant |
| Extended AAA-ATPase domain | 0.08921 | INHERITED FROM: spontaneous mutation rate increased || protein expression increased || sick || response to bacteria variant |
| Tetratricopeptide repeat (TPR) | 0.09709 | INHERITED FROM: organism metabolism processing variant |
| Motor proteins | 0.1153 | INHERITED FROM: male response to hermaphrodite variant || sexually dimorphic mechanosensation variant |
| HLH, helix-loop-helix DNA-binding domain | 0.1153 | INHERITED FROM: pathogen resistance increased || ectopic expression transgene || RNA expression variant || gene expression level reduced || aqueous positive chemotaxis defective || fungal resistance increased || lysine chemotaxis defective |
| Calcium ATPase, transduction domain A | 0.1565 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive |
| Cyclin | 0.1925 | INHERITED FROM: level of transgene expression variant |
| DBL homology domain (DH-domain) | 0.1925 | INHERITED FROM: pathogen resistance increased || organism environmental stimulus response variant || response to bacteria variant || aldicarb response variant || bacterially unswollen || organism pathogen response variant |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.1925 | INHERITED FROM: gene expression variant || organism environmental stimulus response variant || oxygen response variant || transgene expression increased || organism toxic chemical response variant || paraquat resistant || hypoxia response variant || paraquat response variant || hypoxia resistant || response to bacteria variant || avoids bacterial lawn |
| Elongation factors | 0.1925 | INHERITED FROM: mRNA levels increased || mRNA levels reduced || protein phosphorylation variant || proteasome core activity variant || protein phosphorylation increased || protein protein interaction variant || protein aggregation variant |
| HMG-box | 0.1925 | INHERITED FROM: maintenance of gene silencing variant || anesthetic response variant |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.1925 | INHERITED FROM: gene expression variant || transgene expression variant || organism environmental stimulus response variant || oxygen response variant || hypoxia response variant || hypoxia resistant || response to bacteria variant || organism metabolism processing variant || avoids bacterial lawn |
| Pepsin-like | 0.2132 | INHERITED FROM: gene expression variant || hypoosmotic shock hypersensitive || transgene expression variant || osmotic integrity variant || transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Cytochrome P450 | 0.2308 | INHERITED FROM: cadmium response variant || metabolite content decreased || metal response variant || cadmium hypersensitive |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2358 | INHERITED FROM: organism environmental stimulus response variant || drug hypersensitive || nicotine hypersensitive |
| Forkhead DNA-binding domain | 0.2358 | INHERITED FROM: gene expression variant || transgene expression variant || transgene subcellular localization variant || pattern of transgene expression variant || organism metabolism processing variant |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2399 | INHERITED FROM: positive chemotaxis defective || embryo osmotic integrity defective early emb || chemotaxis variant || egg integrity defective early emb || odorant chemosensory response variant || odorant positive chemotaxis defective |
| Acetylcholinesterase-like | 0.2585 | INHERITED FROM: acetylcholinesterase activity variant || enzyme activity reduced || enzyme activity variant || acetylcholinesterase reduced |
| Bromodomain | 0.261 | INHERITED FROM: gene expression variant || anesthetic resistant || organism UV response variant || acute functional tolerance to alcohol defective || sick || ethanol resistant || drug adaptation variant || organism UV hypersensitive || anesthetic response variant |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.261 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Ankyrin repeat | 0.2781 | INHERITED FROM: organism heat response variant || odorant negative chemotaxis defective || octanol chemotaxis defective || octanol chemotaxis variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.2781 | INHERITED FROM: nicotine resistant || cholinergic agonist resistant || DMPP response variant || hypoosmotic shock hypersensitive || selenium response variant || positive chemotaxis variant || slowing response on food variant || antihelmintic response variant || DMPP resistant || thermosensory behavior variant || drug response variant || organism environmental stimulus response variant || benzaldehyde chemotaxis variant || sodium chloride chemotaxis variant || chemosensory response variant || chemical response variant || thermotaxis variant || chemical resistant || AWC odorant chemotaxis variant || mechanosensation variant |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.2885 | INHERITED FROM: organism toxic chemical response variant || paraquat response variant || pesticide response variant || organism oxidative stress response variant |
| Meta-cation ATPase, catalytic domain P | 0.3191 | INHERITED FROM: nicotine response variant || organism environmental stimulus response variant || nicotine hypersensitive |
| Crotonase-like | 0.3191 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3191 | INHERITED FROM: protein subcellular localization variant || pattern protein expression variant || sick || response to bacteria variant || pattern of transgene expression variant || avoids bacterial lawn || protein protein interaction variant || protein aggregation variant |
| PX domain | 0.3533 | INHERITED FROM: protein subcellular localization variant || protein expression variant |
| BTB/POZ domain | 0.3864 | INHERITED FROM: chemical hypersensitive || L1 arrest || resistant to protein aggregation induced paralysis || protein aggregation induced behavior variant || early larval arrest |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4017 | INHERITED FROM: gene expression variant || pathogen induced antimicrobial gene expression variant || protein subcellular localization variant || thermosensory behavior variant || organism stress response variant || pathogen induced gene expression variant || drug induced gene expression variant || drug resistant || thermotaxis variant || response to injury variant || odorant positive chemotaxis variant || nose touch variant || antimicrobial gene expression variant || chemical resistant || aldicarb response variant || organism temperature response variant |
| FKBP immunophilin/proline isomerase | 0.4292 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || protein protein interaction variant || protein aggregation variant |
| Cation efflux protein transmembrane domain-like | 0.4292 | INHERITED FROM: cadmium response variant || chemical hypersensitive || metal response variant || manganese toxicity resistant || cadmium hypersensitive || manganese response variant |
| PHD domain | 0.4315 | INHERITED FROM: gene expression variant || transgene expression variant || transgene subcellular localization variant || protein methylation variant || organism environmental stimulus response variant || organism UV response variant || organism UV hypersensitive || protein modification variant || RNAi resistant || organism metabolism processing variant |
| Glutathione S-transferase (GST), N-terminal domain | 0.4541 | INHERITED FROM: enzyme activity reduced || chemical hypersensitive || organism stress response variant || enzyme activity variant || organism heat hypersensitive || organism toxic chemical response variant || paraquat response variant || metal response variant || organism electrophilic stress hypersensitive |
| Nicotinic receptor ligand binding domain-like | 0.465 | INHERITED FROM: nicotine resistant || cholinergic agonist resistant || DMPP response variant || hypoosmotic shock hypersensitive || selenium response variant || positive chemotaxis variant || slowing response on food variant || antihelmintic response variant || DMPP resistant || thermosensory behavior variant || drug response variant || organism environmental stimulus response variant || benzaldehyde chemotaxis variant || sodium chloride chemotaxis variant || chemosensory response variant || chemical response variant || thermotaxis variant || chemical resistant || AWC odorant chemotaxis variant || mechanosensation variant |
| Hect, E3 ligase catalytic domain | 0.4714 | INHERITED FROM: germ cell ionizing radiation response variant || gene expression variant || transgene expression variant || transgene subcellular localization variant || cell ionizing radiation response variant || protein aggregation induced behavior variant || protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Pyridoxal-dependent decarboxylase | 0.4714 | INHERITED FROM: egg laying response to drug variant || carbon dioxide response variant || carbon dioxide avoidance variant |
| I set domains | 0.4916 | INHERITED FROM: growth rate variant || protein degradation variant || aldicarb response variant |
| Papain-like | 0.496 | INHERITED FROM: gene expression variant || hypoosmotic shock hypersensitive || transgene expression variant || osmotic integrity variant || protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Calpain large subunit, middle domain (domain III) | 0.5196 | INHERITED FROM: metabolic pathway variant || protein degradation variant || protein metabolism variant |
| Gastric lipase | 0.5196 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Myb/SANT domain | 0.5196 | INHERITED FROM: growth rate variant |
| Protein kinases, catalytic subunit | 0.5383 | INHERITED FROM: kinase activity reduced || anoxia response variant || positive chemotaxis variant || protein subcellular localization variant || copper hypersensitive || colchicine resistant || protein expression variant || conflicting sensory integration variant || oxygen response variant || drug induced gene expression variant || anoxia resistant || chemical response variant || protein phosphorylation variant || transgene expression reduced || hypoxia response variant || lipid synthesis increased || alkaline pH chemotaxis variant || protein modification variant || second messenger mediated signaling variant || egg laying response to food variant || octanol chemotaxis defective || metal response variant || protein phosphorylation reduced || aldicarb response variant || mechanosensation variant |
| UBC-related | 0.5482 | INHERITED FROM: gene expression variant || transgene expression variant || transgene subcellular localization variant || protein interaction variant || late larval arrest || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| WW domain | 0.5573 | INHERITED FROM: maintenance of gene silencing variant |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.5687 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
| SH2 domain | 0.5729 | INHERITED FROM: protein expression variant || protein expression reduced || level of protein expression variant |
| Synaptotagmin-like (S variant) | 0.5926 | INHERITED FROM: acetylcholinesterase inhibitor resistant || protein subcellular localization variant || drug response variant || pattern protein expression variant || drug resistant || acetylcholinesterase inhibitor response variant || chemical resistant |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.6347 | INHERITED FROM: gene expression variant || transgene expression variant || protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| Transforming growth factor (TGF)-beta | 0.6893 | INHERITED FROM: drug response variant || nicotine response variant || level of transgene expression variant || transgene expression reduced || levamisole response variant |
| Frizzled cysteine-rich domain | 0.6893 | INHERITED FROM: transgene expression reduced || antibody staining variant |
| EF-hand modules in multidomain proteins | 0.6893 | INHERITED FROM: cell stress response variant || protein expression variant |
| Ubiquitin-related | 0.7133 | INHERITED FROM: transgene expression variant || protein interaction variant || hypersensitive to protein aggregation induced paralysis || protein protein interaction variant || protein aggregation variant |
| Voltage-gated potassium channels | 0.7449 | INHERITED FROM: growth rate variant || adrenergic receptor antagonist response variant || phentolamine resistant || protein degradation variant || serotonin resistant || serotonin response variant |
| H-NOX domain | 0.7563 | INHERITED FROM: drug response variant || carbon dioxide response variant || anesthetic response variant || carbon dioxide avoidance variant |
| Bacterial lipase | 0.7563 | INHERITED FROM: lipid metabolism variant || fat content variant |
| MIT domain | 0.7563 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Hemocyanin middle domain | 0.7563 | INHERITED FROM: germ cell ionizing radiation response variant || cell stress response variant || organism ionizing radiation response variant || cell ionizing radiation response variant |
| Cdc48 N-terminal domain-like | 0.7563 | INHERITED FROM: metabolic pathway variant || transgene expression reduced || protein interaction variant || protein metabolism variant || protein protein interaction variant || protein aggregation variant |
| AAT-like | 0.8231 | INHERITED FROM: growth rate variant |
| LIM domain | 0.8231 | INHERITED FROM: protein degradation variant || protein expression reduced || level of protein expression variant |
| Cyclophilin (peptidylprolyl isomerase) | 0.8408 | INHERITED FROM: transgene expression variant || transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || protein protein interaction variant || protein aggregation variant |
| Glutathione S-transferase (GST), C-terminal domain | 0.8608 | INHERITED FROM: enzyme activity reduced || organism stress response variant || enzyme activity variant || organism heat hypersensitive || metal response variant || cadmium hypersensitive || organism electrophilic stress hypersensitive |
| Calmodulin-like | 0.8723 | INHERITED FROM: protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Leucine zipper domain | 0.8802 | INHERITED FROM: mRNA levels reduced || pathogen susceptibility increased || level of transgene expression variant || pore forming toxin response variant || transgene expression reduced |
| Extended PAW domain | 0.8947 | INHERITED FROM: transgene subcellular localization variant || protein interaction variant || pattern of transgene expression variant || protein protein interaction variant || protein aggregation variant |
| SNF-like | 0.8947 | INHERITED FROM: drug hypersensitive |
| Thioltransferase | 0.9207 | INHERITED FROM: protein aggregation induced behavior variant |
| Adenylyl and guanylyl cyclase catalytic domain | 0.9356 | INHERITED FROM: osmotic avoidance variant || diacetyl chemotaxis variant || anion positive chemotaxis defective || lithium chemotaxis defective || positive chemotaxis variant || magnesium chemotaxis defective || organism environmental stimulus response variant || bromide chemotaxis variant || iodide chemotaxis defective || chemosensory response variant || chemotaxis variant || iodide chemotaxis variant || carbon dioxide response variant || chemical response variant || alkaline pH chemotaxis variant || anesthetic response variant || bromide chemotaxis defective || cation positive chemotaxis variant || second messenger mediated signaling variant || aqueous chemosensory response variant || cation positive chemotaxis defective || AWC odorant chemotaxis variant || AWC odorant chemotaxis defective |
| Ribonuclease PH domain 2-like | 0.9358 | INHERITED FROM: early larval arrest |
| Ribonuclease PH domain 1-like | 0.9358 | INHERITED FROM: early larval arrest |
| L-arabinose binding protein-like | 0.9585 | INHERITED FROM: anion positive chemotaxis variant || anion positive chemotaxis defective || lithium chemotaxis defective || magnesium chemotaxis defective || thermosensory behavior variant || organism environmental stimulus response variant || bromide chemotaxis variant || iodide chemotaxis defective || chemosensory response variant || chemotaxis variant || iodide chemotaxis variant || thermotaxis variant || alkaline pH chemotaxis variant || bromide chemotaxis defective || cation positive chemotaxis variant || aqueous positive chemotaxis variant || cation positive chemotaxis defective || organism temperature response variant |
| Cold shock DNA-binding domain-like | 0.988 | INHERITED FROM: nonsense mRNA accumulation || sick || RNA metabolism variant || mRNA surveillance defective |
| Choline/Carnitine O-acyltransferase | 0.9881 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Glutathione peroxidase-like | 1 | INHERITED FROM: paraquat hypersensitive || organism toxic chemical response variant || paraquat response variant || pesticide response variant |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis || protein aggregation induced behavior variant |
| GABA-aminotransferase-like | 1 | INHERITED FROM: fat content reduced |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: lipid metabolism variant || organism metabolism processing variant |
| PAZ domain | 1 | INHERITED FROM: mRNA levels increased || siRNA expression variant || RNAi enhanced || maintenance of gene silencing variant || RNA expression variant || 21U RNA expression variant || somatic transgene silencing variant || RNAi response variant |
| Insulin-like | 1 | INHERITED FROM: temperature induced dauer formation variant |
| Nuclear receptor | 1 | INHERITED FROM: SDS sensitive dauer || fat content increased || transgene expression reduced || gene expression level reduced || gene expression level high |
| N-acetyl transferase, NAT | 1 | INHERITED FROM: ectopic expression transgene |
| RING finger domain, C3HC4 | 1 | INHERITED FROM: germ cell ionizing radiation response variant || transgene subcellular localization variant || germ cell hypersensitive ionizing radiation || protein interaction variant || pattern of transgene expression variant || organism metabolism processing variant || protein protein interaction variant || protein aggregation variant |
| MSP-like | 1 | INHERITED FROM: lipid metabolism variant || fat content variant |
| B-box zinc-binding domain | 1 | INHERITED FROM: transgene expression variant || transgene subcellular localization variant || protein interaction variant || protein protein interaction variant || protein aggregation variant |
| Histone lysine methyltransferases | 1 | INHERITED FROM: gene expression variant || metabolic pathway variant || protein methylation variant || ectopic expression antibody || maintenance of gene silencing variant || protein modification variant || histone methylation variant || pattern of transgene expression variant || organism metabolism processing variant || protein metabolism variant || mRNA expression variant || RNAi response variant |
| DnaQ-like 3'-5' exonuclease | 1 | INHERITED FROM: RNAi response variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: SDS sensitive dauer || fat content increased || transgene expression reduced || gene expression level reduced || gene expression level high |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 1 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Rhodopsin-like | 1 | INHERITED FROM: locomotion rate serotonin variant || cyproheptadine resistant || drug withdrawal response variant || egg laying response to drug variant || male tail curling serotonin variant || serotonin resistant || serotonin response variant || serotonin induced pumping variant || mianserin resistant || serotonin induced fat reduction variant || aqueous adaptation defective || methiothepin resistant || biogenic amine receptor antagonist resistant || organism pathogen response variant || serotonin hypersensitive |
| Double-stranded RNA-binding domain (dsRBD) | 1 | INHERITED FROM: maintenance of gene silencing variant || miRNA expression variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Chitinase insertion domain | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| GAPDH-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| PDI-like | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| CAT-like | 0 | Direct |
| Reductases | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| BAR domain | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| MIR domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Nop domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Internalin LRR domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Phosphotyrosine-binding domain (PTB) | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| PEP carboxykinase C-terminal domain | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| La domain | 0 | Direct |
| t-snare proteins | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Annexin | 0 | Direct |
| Brix domain | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
| Nucleosome core histones | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| Heme-dependent catalases | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| WGR domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| SWIRM domain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| First domain of FERM | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| FF domain | 0 | Direct |
| Cullin repeat | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| CUT domain | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| SMAD domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Fatty acid binding protein-like | 0 | Direct |
| ARID domain | 0 | Direct |
| Tubulin, GTPase domain | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| TBP-associated factors, TAFs | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| WWE domain | 0 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| 28-residue LRR | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| YWTD domain | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| COMT-like | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Hexokinase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| HSP20 | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| PUA domain | 0 | Direct |
| U-box | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Tetraspanin | 0 | Direct |
| Subtilases | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| MutT-like | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| Vertebrate phospholipase A2 | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| GAS2 domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| Glycogenin | 0 | Direct |
| D-aminoacid oxidase, N-terminal domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| GYF domain | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| Acireductone dioxygenase | 0 | Direct |
| PhzC/PhzF-like | 0 | Direct |
| LysM domain | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Cadherin | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| MFPT repeat | 0 | Direct |
| Sec7 domain | 0 | Direct |
| PDZ domain | 0 | Direct |
| Acyl-CoA thioesterase | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| Mammalian PLC | 0 | Direct |
| Paired domain | 0 | Direct |
| Chromo domain | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| LEM domain | 0 | Direct |
| DEP domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| CoA transferase alpha subunit-like | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| LacY-like proton/sugar symporter | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Troponin I | 0 | Direct |
| Adenain-like | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| CO dehydrogenase flavoprotein N-terminal domain-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| IF2B-like | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| Class I aldolase | 0 | Direct |
| VHS domain | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| AMPK-beta glycogen binding domain-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| YbiA-like | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Integrin domains | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| PDEase | 0 | Direct |
| Peptidylglycine alpha-hydroxylating monooxygenase, PHM | 0 | Direct |
| Choline kinase | 0 | Direct |
| Elafin-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| ets domain | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| Glutaminase | 0 | Direct |
| Bactericidal permeability-increasing protein, BPI | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| YihX-like | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| Tubulin, C-terminal domain | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| CoA-binding domain | 0 | Direct |
| UBA domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| FHA domain | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| PaaI/YdiI-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| HD domain | 0 | Direct |
| SAND domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| NHL repeat | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Arfaptin, Rac-binding fragment | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| Tandem AAA-ATPase domain | 0.002575 | Inherited |
| ABC transporter ATPase domain-like | 0.007482 | Inherited |
| Homeodomain | 0.02783 | Inherited |
| G proteins | 0.03312 | Inherited |
| WD40-repeat | 0.03433 | Inherited |
| ABC transporter transmembrane region | 0.03603 | Inherited |
| SH3-domain | 0.06044 | Inherited |
| CCCH zinc finger | 0.07548 | Inherited |
| Canonical RBD | 0.07909 | Inherited |
| Extended AAA-ATPase domain | 0.08921 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.09709 | Inherited |
| Motor proteins | 0.1153 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.1153 | Inherited |
| Calcium ATPase, transduction domain A | 0.1565 | Inherited |
| Cyclin | 0.1925 | Inherited |
| DBL homology domain (DH-domain) | 0.1925 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.1925 | Inherited |
| Elongation factors | 0.1925 | Inherited |
| HMG-box | 0.1925 | Inherited |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0.1925 | Inherited |
| Pepsin-like | 0.2132 | Inherited |
| Cytochrome P450 | 0.2308 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.2358 | Inherited |
| Forkhead DNA-binding domain | 0.2358 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.2399 | Inherited |
| Acetylcholinesterase-like | 0.2585 | Inherited |
| Bromodomain | 0.261 | Inherited |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0.261 | Inherited |
| Ankyrin repeat | 0.2781 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.2781 | Inherited |
| FAD/NAD-linked reductases, N-terminal and central domains | 0.2885 | Inherited |
| Meta-cation ATPase, catalytic domain P | 0.3191 | Inherited |
| Crotonase-like | 0.3191 | Inherited |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0.3191 | Inherited |
| PX domain | 0.3533 | Inherited |
| BTB/POZ domain | 0.3864 | Inherited |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0.4017 | Inherited |
| FKBP immunophilin/proline isomerase | 0.4292 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.4292 | Inherited |
| PHD domain | 0.4315 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.4541 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.465 | Inherited |
| Hect, E3 ligase catalytic domain | 0.4714 | Inherited |
| Pyridoxal-dependent decarboxylase | 0.4714 | Inherited |
| I set domains | 0.4916 | Inherited |
| Papain-like | 0.496 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.5196 | Inherited |
| Gastric lipase | 0.5196 | Inherited |
| Myb/SANT domain | 0.5196 | Inherited |
| Protein kinases, catalytic subunit | 0.5383 | Inherited |
| UBC-related | 0.5482 | Inherited |
| WW domain | 0.5573 | Inherited |
| Class I alpha-1;2-mannosidase, catalytic domain | 0.5687 | Inherited |
| SH2 domain | 0.5729 | Inherited |
| Synaptotagmin-like (S variant) | 0.5926 | Inherited |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0.6347 | Inherited |
| Transforming growth factor (TGF)-beta | 0.6893 | Inherited |
| Frizzled cysteine-rich domain | 0.6893 | Inherited |
| EF-hand modules in multidomain proteins | 0.6893 | Inherited |
| Ubiquitin-related | 0.7133 | Inherited |
| Voltage-gated potassium channels | 0.7449 | Inherited |
| H-NOX domain | 0.7563 | Inherited |
| Bacterial lipase | 0.7563 | Inherited |
| MIT domain | 0.7563 | Inherited |
| Hemocyanin middle domain | 0.7563 | Inherited |
| Cdc48 N-terminal domain-like | 0.7563 | Inherited |
| AAT-like | 0.8231 | Inherited |
| LIM domain | 0.8231 | Inherited |
| Cyclophilin (peptidylprolyl isomerase) | 0.8408 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.8608 | Inherited |
| Calmodulin-like | 0.8723 | Inherited |
| Leucine zipper domain | 0.8802 | Inherited |
| Extended PAW domain | 0.8947 | Inherited |
| SNF-like | 0.8947 | Inherited |
| Thioltransferase | 0.9207 | Inherited |
| Adenylyl and guanylyl cyclase catalytic domain | 0.9356 | Inherited |
| Ribonuclease PH domain 2-like | 0.9358 | Inherited |
| Ribonuclease PH domain 1-like | 0.9358 | Inherited |
| L-arabinose binding protein-like | 0.9585 | Inherited |
| Cold shock DNA-binding domain-like | 0.988 | Inherited |
| Choline/Carnitine O-acyltransferase | 0.9881 | Inherited |
| Glutathione peroxidase-like | 1 | Inherited |
| F-box domain | 1 | Inherited |
| GABA-aminotransferase-like | 1 | Inherited |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 1 | Inherited |
| PAZ domain | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| Nuclear receptor | 1 | Inherited |
| N-acetyl transferase, NAT | 1 | Inherited |
| RING finger domain, C3HC4 | 1 | Inherited |
| MSP-like | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Histone lysine methyltransferases | 1 | Inherited |
| DnaQ-like 3'-5' exonuclease | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| Double-stranded RNA-binding domain (dsRBD) | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Ribosomal protein L10-like | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Ribosomal protein S10 | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| PEP carboxykinase-like | 0 | DIRECT |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Hypothetical protein c14orf129, hspc210 | 0 | DIRECT |
| Ribosomal protein S18 | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Elafin-like | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Clc chloride channel | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Heme-dependent catalase-like | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Hedgehog/intein (Hint) domain | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| t-snare proteins | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Profilin (actin-binding protein) | 0 | DIRECT |
| PEP carboxykinase N-terminal domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| CBD9-like | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Diaminopimelate epimerase-like | 0 | DIRECT |
| YbiA-like | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Fibrinogen C-terminal domain-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Pepsin inhibitor-3 | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| PurM N-terminal domain-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| Intermediate filament protein, coiled coil region | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| MFPT repeat-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Galactose oxidase, central domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| PHM/PNGase F | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| GAS2 domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| PurM C-terminal domain-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| ISP domain | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Mitochondrial carrier | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Rap/Ran-GAP | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Molybdenum cofactor-binding domain | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| MgtE membrane domain-like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Small-conductance potassium channel | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| CO dehydrogenase ISP C-domain like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| PH domain-like | 0.00001044 | DIRECT |
| PDZ domain-like | 0.006149 | INHERITED FROM: acetylcholinesterase inhibitor response variant || chemical resistant || aldicarb response variant || drug resistant || protein expression variant |
| TPR-like | 0.008382 | INHERITED FROM: positive chemotaxis defective || ivermectin resistant || antihelmintic response variant || ivermectin response variant || light body touch resistant || chemotaxis variant |
| ARM repeat | 0.01204 | INHERITED FROM: RNAi response variant || sick || organism metabolism processing variant || protein expression variant || gene expression variant |
| ABC transporter transmembrane region | 0.01495 | INHERITED FROM: RNAi response variant || chemical response variant || metal response variant || cadmium response variant || RNAi resistant || colchicine hypersensitive || chemical hypersensitive || cadmium hypersensitive |
| SH3-domain | 0.03519 | INHERITED FROM: protein phosphorylation variant || protein expression reduced || aldicarb response variant || protein expression variant || protein metabolism variant |
| Homeodomain-like | 0.03632 | INHERITED FROM: ectopic expression transgene || adrenergic receptor antagonist response variant || imipramine resistant || growth rate variant || organism metabolism processing variant || phentolamine resistant || egg laying imipramine resistant || protein degradation variant || level of transgene expression variant || carbon dioxide response variant || carbon dioxide avoidance variant |
| WD40 repeat-like | 0.04264 | INHERITED FROM: protein protein interaction variant || late larval arrest || osmotic avoidance variant || organism metabolism processing variant || pathogen induced antimicrobial gene expression variant || aldicarb response variant || protein aggregation induced behavior variant || protein aggregation variant || early larval arrest |
| CCCH zinc finger | 0.05551 | INHERITED FROM: ectopic expression transgene || mRNA expression ectopic || transgene expression variant || gene expression variant |
| Translation proteins | 0.07024 | INHERITED FROM: protein protein interaction variant || sick || protein phosphorylation increased || mRNA levels increased || organism metabolism processing variant || protein phosphorylation variant || proteasome core activity variant || transgene expression variant || protein aggregation variant || gene expression variant |
| "Winged helix" DNA-binding domain | 0.07068 | INHERITED FROM: protein protein interaction variant || spontaneous mutation rate increased || germline transgene silencing variant || protein expression increased || organism metabolism processing variant || anesthetic response variant || protein aggregation induced behavior variant || protein aggregation variant |
| HLH, helix-loop-helix DNA-binding domain | 0.08068 | INHERITED FROM: aqueous positive chemotaxis defective || ectopic expression transgene || organism metabolism processing variant || gene expression level reduced || RNA expression variant || hypoxia response variant || lysine chemotaxis defective || pathogen resistance increased || fungal resistance increased |
| SMAD/FHA domain | 0.08858 | INHERITED FROM: fat content reduced || aldicarb response variant |
| Calcium ATPase, transmembrane domain M | 0.09956 | INHERITED FROM: drug hypersensitive || lipid composition variant || nicotine hypersensitive |
| EGF/Laminin | 0.1071 | INHERITED FROM: octanol chemotaxis variant || odorant negative chemotaxis defective || octanol chemotaxis defective |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1119 | INHERITED FROM: drug hypersensitive || lipid composition variant || nicotine hypersensitive |
| Regulator of G-protein signaling, RGS | 0.1119 | INHERITED FROM: mechanosensation variant || chemotaxis variant || negative chemotaxis variant |
| Acid proteases | 0.1257 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || osmotic integrity variant || organism metabolism processing variant || protein interaction variant || hypoosmotic shock hypersensitive || transgene expression variant || protein aggregation variant || gene expression variant |
| Calcium ATPase, transduction domain A | 0.1257 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive || organism environmental stimulus response variant |
| Cysteine-rich domain | 0.1298 | INHERITED FROM: response to injury variant || bacterially unswollen || acetylcholinesterase inhibitor response variant || positive chemotaxis variant || organism stress response variant || organism metabolism processing variant || odorant positive chemotaxis variant || pathogen induced antimicrobial gene expression variant || thermosensory behavior variant || pathogen induced gene expression variant || odorant chemosensory response variant || aldicarb response variant || drug induced gene expression variant || protein subcellular localization variant || antimicrobial gene expression variant || thermotaxis variant || gene expression variant |
| Quinoprotein alcohol dehydrogenase-like | 0.1407 | INHERITED FROM: L2 arrest || mRNA levels increased || hypoxia response variant || oxygen response variant || protein degradation variant || mid larval arrest |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1422 | INHERITED FROM: positive chemotaxis defective || odorant positive chemotaxis defective || embryo osmotic integrity defective early emb || odorant chemosensory response variant || egg integrity defective early emb || chemotaxis variant |
| Cytochrome P450 | 0.1463 | INHERITED FROM: metal response variant || cadmium response variant || cadmium hypersensitive || metabolite content decreased |
| (Trans)glycosidases | 0.1557 | INHERITED FROM: pathogen susceptibility increased |
| P-loop containing nucleoside triphosphate hydrolases | 0.1574 | INHERITED FROM: spontaneous mutation rate increased || RNAi response variant || organism UV response variant || sick || hydroxyurea response variant || organism metabolism processing variant || organism hypersensitive ionizing radiation || RNAi resistant || aldicarb response variant || pathogen release variant || chemotaxis variant || organism environmental stimulus response variant || pattern of transgene expression variant || carbon dioxide avoidance variant |
| HMG-box | 0.158 | INHERITED FROM: anesthetic response variant || transgene expression variant || maintenance of gene silencing variant |
| DBL homology domain (DH-domain) | 0.158 | INHERITED FROM: response to bacteria variant || bacterially unswollen || organism pathogen response variant || pathogen resistance increased || aldicarb response variant || organism environmental stimulus response variant |
| ClpP/crotonase | 0.158 | INHERITED FROM: level of transgene expression variant || lipid metabolism variant || fat content variant |
| Ankyrin repeat | 0.1678 | INHERITED FROM: organism heat response variant || octanol chemotaxis variant || odorant negative chemotaxis defective || octanol chemotaxis defective || chemotaxis variant || chemosensory response variant |
| Cysteine proteinases | 0.1979 | INHERITED FROM: protein protein interaction variant || osmotic integrity variant || organism metabolism processing variant || paraquat hypersensitive || protein interaction variant || hypoosmotic shock hypersensitive || protein aggregation variant || pattern of transgene expression variant |
| POZ domain | 0.2033 | INHERITED FROM: L1 arrest || protein aggregation induced behavior variant || early larval arrest || resistant to protein aggregation induced paralysis |
| Cyclin-like | 0.2044 | INHERITED FROM: protein phosphorylation reduced || protein phosphorylation variant || level of transgene expression variant |
| Bromodomain | 0.2221 | INHERITED FROM: organism UV response variant || sick || ethanol resistant || organism UV hypersensitive || organism metabolism processing variant || drug adaptation variant || acute functional tolerance to alcohol defective || anesthetic resistant || anesthetic response variant || gene expression variant |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2221 | INHERITED FROM: lipid metabolism variant || fat content variant |
| Tudor/PWWP/MBT | 0.2221 | INHERITED FROM: pattern of transgene expression variant |
| Metallo-dependent phosphatases | 0.2352 | INHERITED FROM: radiation induced germ cell apoptosis variant || germ cell resistant ionizing radiation |
| RNA-binding domain, RBD | 0.2387 | INHERITED FROM: sick || no induction of antimicrobial peptide expression after infection || organism metabolism processing variant || mRNA export variant || starvation induced apoptosis variant || RNA expression variant || innate immune response variant || pathogen induced antimicrobial gene expression variant || RNA metabolism variant || RNA processing variant || alternative splicing variant || maintenance of gene silencing variant |
| Lipocalins | 0.243 | INHERITED FROM: paraquat hypersensitive || lipid metabolism variant || fat content increased || fat content variant |
| SNARE-like | 0.2486 | INHERITED FROM: transgene subcellular localization variant || sick || organism metabolism processing variant || aldicarb resistant || acetylcholinesterase inhibitor resistant || transgene expression variant || pattern of transgene expression variant || gene expression variant |
| Cation efflux protein transmembrane domain-like | 0.3116 | INHERITED FROM: metal response variant || manganese response variant || manganese toxicity resistant || cadmium hypersensitive |
| PX domain | 0.3116 | INHERITED FROM: protein expression reduced || protein subcellular localization variant || protein expression variant |
| Nicotinic receptor ligand binding domain-like | 0.3168 | INHERITED FROM: drug response variant || selenium response variant || sodium chloride chemotaxis variant || DMPP response variant || AWC odorant chemotaxis variant || chemical response variant || positive chemotaxis variant || chemical resistant || mechanosensation variant || nicotine resistant || slowing response on food variant || cholinergic agonist resistant || antihelmintic response variant || thermosensory behavior variant || DMPP resistant || benzaldehyde chemotaxis variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || thermotaxis variant || chemosensory response variant |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3558 | INHERITED FROM: drug response variant || selenium response variant || sodium chloride chemotaxis variant || DMPP response variant || AWC odorant chemotaxis variant || chemical response variant || positive chemotaxis variant || chemical resistant || mechanosensation variant || nicotine resistant || slowing response on food variant || cholinergic agonist resistant || antihelmintic response variant || thermosensory behavior variant || DMPP resistant || benzaldehyde chemotaxis variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || thermotaxis variant || chemosensory response variant |
| RNI-like | 0.3715 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| FKBP-like | 0.3869 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || protein interaction variant || protein aggregation variant || pattern of transgene expression variant |
| HD-domain/PDEase-like | 0.3869 | INHERITED FROM: thermosensory behavior variant || organism temperature response variant || thermotaxis variant |
| Class II aaRS and biotin synthetases | 0.3977 | INHERITED FROM: response to bacteria variant || organism metabolism processing variant || hypoxia resistant || hypoxia response variant || oxygen response variant || avoids bacterial lawn || organism environmental stimulus response variant || transgene expression variant || gene expression variant |
| Hect, E3 ligase catalytic domain | 0.4309 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || organism metabolism processing variant || germ cell ionizing radiation response variant || protein interaction variant || protein aggregation induced behavior variant || cell ionizing radiation response variant || transgene expression variant || protein aggregation variant || pattern of transgene expression variant || gene expression variant |
| PRTase-like | 0.4309 | INHERITED FROM: Fluorouracil resistant || drug resistant |
| Myosin rod fragments | 0.4309 | INHERITED FROM: drug resistant |
| DHS-like NAD/FAD-binding domain | 0.4309 | INHERITED FROM: protein acetylation variant || metabolic pathway variant || protein expression variant |
| Galactose-binding domain-like | 0.4508 | INHERITED FROM: protein protein interaction variant || protein interaction variant || protein aggregation variant |
| SH2 domain | 0.452 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein expression variant |
| Cystine-knot cytokines | 0.4624 | INHERITED FROM: nicotine response variant || levamisole response variant |
| Sm-like ribonucleoproteins | 0.4624 | INHERITED FROM: sick || organism heat response variant || response to bacteria variant || unfolded protein response variant || avoids bacterial lawn || protein subcellular localization variant || transgene expression variant || pattern of transgene expression variant |
| Voltage-gated potassium channels | 0.4761 | INHERITED FROM: positive chemotaxis defective || adrenergic receptor antagonist response variant || imipramine resistant || growth rate variant || serotonin response variant || mechanosensation variant || phentolamine resistant || protein degradation variant || serotonin resistant |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.479 | INHERITED FROM: pattern protein expression variant |
| Calpain large subunit, middle domain (domain III) | 0.479 | INHERITED FROM: metabolic pathway variant || protein degradation variant || protein metabolism variant |
| Riboflavin synthase domain-like | 0.479 | INHERITED FROM: pattern protein expression variant |
| WW domain | 0.4964 | INHERITED FROM: aldicarb resistant || acetylcholinesterase inhibitor resistant || maintenance of gene silencing variant |
| UBC-like | 0.4982 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || sick || late larval arrest || organism metabolism processing variant || protein interaction variant || protein aggregation variant || pattern of transgene expression variant |
| SAM/Pointed domain | 0.4995 | INHERITED FROM: gene expression level reduced || aldicarb response variant |
| Protein kinase-like (PK-like) | 0.5038 | INHERITED FROM: protein phosphorylation reduced || aqueous chemosensory response variant || protein modification variant || alkaline pH chemotaxis variant || kinase activity reduced || transgene expression reduced || chemical response variant || positive chemotaxis variant || egg laying response to food variant || protein phosphorylation variant || mechanosensation variant || organism oxidative stress response variant || metal response variant || hypoxia response variant || organism osmotic stress hypersensitive || metabolic pathway variant || colchicine resistant || mid larval arrest || anoxia resistant || aldicarb response variant || lipid synthesis increased || drug induced gene expression variant || protein subcellular localization variant || octanol chemotaxis defective || conflicting sensory integration variant || protein expression variant || organism environmental stimulus response variant || second messenger mediated signaling variant || copper hypersensitive |
| Seven-hairpin glycosidases | 0.5337 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
| Multidrug resistance efflux transporter EmrE | 0.5352 | INHERITED FROM: response to bacteria variant || bacterially unswollen || pathogen resistance increased |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.555 | INHERITED FROM: RNAi response variant || response to injury variant || chemical response variant || egg laying serotonin variant || growth rate variant || cell stress response variant || chemical resistant || pathogen induced antimicrobial gene expression variant || organism osmotic stress response variant || cellular osmotic stress response variant || drug resistant || drug induced gene expression variant || protein subcellular localization variant || protein expression variant || organism environmental stimulus response variant |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.586 | INHERITED FROM: cell gamma ray response variant || organism gamma ray response variant || gamma ray induced apoptosis increased |
| Di-copper centre-containing domain | 0.5896 | INHERITED FROM: organism stress response variant || cell stress response variant || germ cell ionizing radiation response variant || organism ionizing radiation response variant || cell ionizing radiation response variant |
| KA1-like | 0.5896 | INHERITED FROM: RNA expression variant |
| HIT/MYND zinc finger-like | 0.6102 | INHERITED FROM: pattern of transgene expression variant |
| GST C-terminal domain-like | 0.637 | INHERITED FROM: enzyme activity variant || organism heat hypersensitive || organism stress response variant || metal response variant || enzyme activity reduced || organism electrophilic stress hypersensitive || cadmium hypersensitive || organism environmental stimulus response variant |
| DNase I-like | 0.6528 | INHERITED FROM: protein expression variant |
| 4Fe-4S ferredoxins | 0.6557 | INHERITED FROM: transgene expression increased |
| Frizzled cysteine-rich domain | 0.6557 | INHERITED FROM: antibody staining variant || transgene expression reduced |
| S15/NS1 RNA-binding domain | 0.6557 | INHERITED FROM: response to bacteria variant || avoids bacterial lawn || transgene expression increased |
| alpha/beta-Hydrolases | 0.6764 | INHERITED FROM: acetylcholinesterase reduced || acetylcholinesterase activity variant |
| Fibronectin type III | 0.7107 | INHERITED FROM: growth rate variant |
| MIT domain | 0.728 | INHERITED FROM: protein protein interaction variant || protein interaction variant || protein aggregation variant |
| ADC-like | 0.728 | INHERITED FROM: protein protein interaction variant || transgene expression reduced || metabolic pathway variant || protein interaction variant || protein aggregation variant || protein metabolism variant |
| Clavaminate synthase-like | 0.7715 | INHERITED FROM: histone methylation variant || protein methylation variant |
| NAD kinase/diacylglycerol kinase-like | 0.7839 | INHERITED FROM: thermosensory behavior variant || thermotaxis variant |
| CoA-dependent acyltransferases | 0.79 | INHERITED FROM: organism metabolism processing variant || lipid metabolism variant |
| Cyclophilin-like | 0.79 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || protein interaction variant || transgene expression variant || protein aggregation variant || pattern of transgene expression variant || gene expression variant |
| EF-hand | 0.8057 | INHERITED FROM: cellular osmotic stress response variant || aldicarb response variant || protein interaction variant || protein aggregation variant |
| SNF-like | 0.8213 | INHERITED FROM: drug hypersensitive |
| Leucine zipper domain | 0.8249 | INHERITED FROM: mRNA expression variant || transgene expression reduced || pathogen susceptibility increased || pore forming toxin response variant || level of transgene expression variant || mRNA levels reduced |
| Eukaryotic type KH-domain (KH-domain type I) | 0.8315 | INHERITED FROM: RNA expression variant |
| GTPase activation domain, GAP | 0.8315 | INHERITED FROM: protein expression variant |
| Ubiquitin-like | 0.8319 | INHERITED FROM: protein protein interaction variant || protein interaction variant || protein aggregation variant |
| Thioredoxin-like | 0.8443 | INHERITED FROM: enzyme activity variant || organism heat hypersensitive || paraquat response variant || organism stress response variant || metal response variant || enzyme activity reduced || organism toxic chemical response variant || organism electrophilic stress hypersensitive |
| Ribonuclease H-like | 0.8672 | INHERITED FROM: RNAi response variant || siRNA expression variant || somatic transgene silencing variant || RNA expression variant || 21U RNA expression variant || RNAi enhanced || maintenance of gene silencing variant |
| Immunoglobulin | 0.8729 | INHERITED FROM: growth rate variant || protein degradation variant || aldicarb response variant |
| p53-like transcription factors | 0.876 | INHERITED FROM: ectopic expression transgene || gene expression level reduced || level of transgene expression variant |
| Nucleic acid-binding proteins | 0.8805 | INHERITED FROM: sick || hydroxyurea response variant || nonsense mRNA accumulation || mRNA surveillance defective || hypoxia resistant || avoids bacterial lawn || hydroxyurea hypersensitive || organism environmental stimulus response variant |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8863 | INHERITED FROM: gene expression level high || transgene expression reduced || gene expression level reduced || SDS sensitive dauer || level of transgene expression variant || fat content increased |
| MFS general substrate transporter | 0.895 | INHERITED FROM: organism high sodium chloride hypersensitive |
| FYVE/PHD zinc finger | 0.9003 | INHERITED FROM: organism UV response variant || protein modification variant || organism UV hypersensitive || organism metabolism processing variant || protein methylation variant || gene expression variant |
| Nucleotide-diphospho-sugar transferases | 0.9025 | INHERITED FROM: lectin response variant || resistant to lectin |
| HAD-like | 0.9096 | INHERITED FROM: nicotine hypersensitive |
| Ribonuclease PH domain 2-like | 0.9123 | INHERITED FROM: early larval arrest |
| Saposin | 0.9346 | INHERITED FROM: radiation induced germ cell apoptosis variant || transgene expression reduced || pathogen load variant || germ cell resistant ionizing radiation || germ cell ionizing radiation response variant || level of transgene expression variant || increased pathogen survival |
| Periplasmic binding protein-like I | 0.9362 | INHERITED FROM: bromide chemotaxis defective || iodide chemotaxis defective || aqueous chemosensory response variant || alkaline pH chemotaxis variant || lithium chemotaxis defective || AWC odorant chemotaxis defective || AWC odorant chemotaxis variant || iodide chemotaxis variant || magnesium chemotaxis defective || aqueous positive chemotaxis variant || mechanosensation variant || bromide chemotaxis variant || thermosensory behavior variant || memory retention defective || benzaldehyde chemotaxis variant || carbon dioxide response variant || organism temperature response variant || diacetyl chemotaxis variant || chemotaxis variant || organism environmental stimulus response variant || second messenger mediated signaling variant || carbon dioxide avoidance variant || thermotaxis variant || chemosensory response variant |
| FAD/NAD(P)-binding domain | 0.9362 | INHERITED FROM: organism oxidative stress response variant || ATP levels reduced || organism toxic chemical response variant || ATP levels variant || pesticide response variant |
| PLP-dependent transferases | 0.9425 | INHERITED FROM: radiation induced germ cell apoptosis variant || germ cell resistant ionizing radiation |
| Nucleotide cyclase | 0.9491 | INHERITED FROM: bromide chemotaxis defective || iodide chemotaxis defective || aqueous chemosensory response variant || alkaline pH chemotaxis variant || lithium chemotaxis defective || AWC odorant chemotaxis defective || AWC odorant chemotaxis variant || iodide chemotaxis variant || magnesium chemotaxis defective || chemical response variant || positive chemotaxis variant || anion positive chemotaxis variant || osmotic avoidance variant || anion positive chemotaxis defective || bromide chemotaxis variant || cation positive chemotaxis defective || cation positive chemotaxis variant || anesthetic response variant || carbon dioxide response variant || diacetyl chemotaxis variant || chemotaxis variant || organism environmental stimulus response variant || second messenger mediated signaling variant || thermotaxis variant || chemosensory response variant |
| Ribosomal protein S5 domain 2-like | 0.9582 | INHERITED FROM: early larval arrest |
| SET domain | 0.9655 | INHERITED FROM: spontaneous mutation rate increased || RNAi response variant || protein modification variant || histone methylation variant || organism metabolism processing variant || protein methylation variant || dosage compensation variant || ectopic expression antibody || pattern of transgene expression variant || gene expression variant || maintenance of gene silencing variant || protein metabolism variant |
| PAZ domain | 0.9724 | INHERITED FROM: RNAi response variant || siRNA expression variant || somatic transgene silencing variant || mRNA levels increased || RNA expression variant || 21U RNA expression variant || RNAi enhanced || maintenance of gene silencing variant |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.9868 | INHERITED FROM: drug response variant || chemical response variant || anesthetic response variant || carbon dioxide response variant || carbon dioxide avoidance variant |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.9913 | INHERITED FROM: ascaroside biosynthesis variant || organism metabolism processing variant || ascaroside biosynthesis defective || lipid metabolism variant |
| Acyl-CoA dehydrogenase NM domain-like | 0.9913 | INHERITED FROM: ascaroside biosynthesis variant || organism metabolism processing variant || ascaroside biosynthesis defective || lipid metabolism variant |
| Nucleotidylyl transferase | 0.9913 | INHERITED FROM: response to bacteria variant || organism metabolism processing variant || paraquat resistant || hypoxia resistant || hypoxia response variant || oxygen response variant || avoids bacterial lawn || transgene expression increased || organism environmental stimulus response variant |
| Translation proteins SH3-like domain | 1 | INHERITED FROM: protein protein interaction variant || response to bacteria variant || organism metabolism processing variant || avoids bacterial lawn || organism environmental stimulus response variant || transgene expression variant || protein aggregation variant || early larval arrest || gene expression variant |
| RING/U-box | 1 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || organism metabolism processing variant || cell stress response variant || germ cell ionizing radiation response variant || germ cell hypersensitive ionizing radiation || organism ionizing radiation response variant || protein interaction variant || cell ionizing radiation response variant || protein aggregation variant || pattern of transgene expression variant || gene expression variant |
| UBA-like | 1 | INHERITED FROM: protein protein interaction variant || protein aggregation variant |
| dsRNA-binding domain-like | 1 | INHERITED FROM: RNA expression variant || maintenance of gene silencing variant |
| Nuclear receptor ligand-binding domain | 1 | INHERITED FROM: gene expression level high || transgene expression reduced || gene expression level reduced || SDS sensitive dauer || level of transgene expression variant || lipid metabolism variant || fat content increased |
| B-box zinc-binding domain | 1 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || organism metabolism processing variant || protein interaction variant || transgene expression variant || protein aggregation variant || gene expression variant |
| Insulin-like | 1 | INHERITED FROM: temperature induced dauer formation variant || fat content variant |
| DNA/RNA polymerases | 1 | INHERITED FROM: DNA metabolism variant || organism UV response variant || organism UV hypersensitive |
| Bet v1-like | 1 | INHERITED FROM: growth rate variant |
| Snake toxin-like | 1 | INHERITED FROM: fat content reduced |
| F-box domain | 1 | INHERITED FROM: resistant to protein aggregation induced paralysis |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: locomotion rate serotonin variant || serotonin induced pumping variant || male tail curling serotonin variant || serotonin induced fat reduction variant |
| PapD-like | 1 | INHERITED FROM: slow growth || larval growth variant || developmental growth variant || lipid metabolism variant || fat content variant || larval arrest |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: inhibitor of serotonin uptake variant || imipramine resistant || organism metabolism processing variant || egg laying imipramine resistant || egg laying serotonin resistant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Ribosomal protein L10-like | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0 | Direct |
| Translational machinery components | 0 | Direct |
| ALDH-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Ribosomal protein S10 | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| PEP carboxykinase-like | 0 | Direct |
| Epsilon subunit of mitochondrial F1F0-ATP synthase | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Hypothetical protein c14orf129, hspc210 | 0 | Direct |
| Ribosomal protein S18 | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Elafin-like | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Clc chloride channel | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Heme-dependent catalase-like | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Tim10-like | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| CO dehydrogenase molybdoprotein N-domain-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Hedgehog/intein (Hint) domain | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| ARID-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| PGBD-like | 0 | Direct |
| t-snare proteins | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Integrin domains | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| PIN domain-like | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Annexin | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| LEM domain | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Profilin (actin-binding protein) | 0 | Direct |
| PEP carboxykinase N-terminal domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| LysM domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| CBD9-like | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Diaminopimelate epimerase-like | 0 | Direct |
| YbiA-like | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| L30e-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Fibrinogen C-terminal domain-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Aldolase | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Pepsin inhibitor-3 | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Cadherin-like | 0 | Direct |
| PurM N-terminal domain-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| HCP-like | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| VPS9 domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| Intermediate filament protein, coiled coil region | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| MFPT repeat-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Galactose oxidase, central domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| GroES-like | 0 | Direct |
| Polo-box domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| PHM/PNGase F | 0 | Direct |
| BEACH domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| FF domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| GAS2 domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Nop domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| PurM C-terminal domain-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| ISP domain | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| SIS domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Mitochondrial carrier | 0 | Direct |
| Cytochrome c | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| DEATH domain | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Rap/Ran-GAP | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| MIR domain | 0 | Direct |
| Molybdenum cofactor-binding domain | 0 | Direct |
| ACP-like | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| SAND domain-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| MgtE membrane domain-like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| Pentein | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| TGS-like | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| HRDC-like | 0 | Direct |
| Small-conductance potassium channel | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| CO dehydrogenase ISP C-domain like | 0 | Direct |
| GYF domain | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| FAD-linked oxidases, C-terminal domain | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Histone-fold | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| PEBP-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| WWE domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| PH domain-like | 0.00001044 | Direct |
| PDZ domain-like | 0.006149 | Inherited |
| TPR-like | 0.008382 | Inherited |
| ARM repeat | 0.01204 | Inherited |
| ABC transporter transmembrane region | 0.01495 | Inherited |
| SH3-domain | 0.03519 | Inherited |
| Homeodomain-like | 0.03632 | Inherited |
| WD40 repeat-like | 0.04264 | Inherited |
| CCCH zinc finger | 0.05551 | Inherited |
| Translation proteins | 0.07024 | Inherited |
| "Winged helix" DNA-binding domain | 0.07068 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.08068 | Inherited |
| SMAD/FHA domain | 0.08858 | Inherited |
| Calcium ATPase, transmembrane domain M | 0.09956 | Inherited |
| EGF/Laminin | 0.1071 | Inherited |
| Metal cation-transporting ATPase, ATP-binding domain N | 0.1119 | Inherited |
| Regulator of G-protein signaling, RGS | 0.1119 | Inherited |
| Acid proteases | 0.1257 | Inherited |
| Calcium ATPase, transduction domain A | 0.1257 | Inherited |
| Cysteine-rich domain | 0.1298 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.1407 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.1422 | Inherited |
| Cytochrome P450 | 0.1463 | Inherited |
| (Trans)glycosidases | 0.1557 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.1574 | Inherited |
| HMG-box | 0.158 | Inherited |
| DBL homology domain (DH-domain) | 0.158 | Inherited |
| ClpP/crotonase | 0.158 | Inherited |
| Ankyrin repeat | 0.1678 | Inherited |
| Cysteine proteinases | 0.1979 | Inherited |
| POZ domain | 0.2033 | Inherited |
| Cyclin-like | 0.2044 | Inherited |
| Bromodomain | 0.2221 | Inherited |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2221 | Inherited |
| Tudor/PWWP/MBT | 0.2221 | Inherited |
| Metallo-dependent phosphatases | 0.2352 | Inherited |
| RNA-binding domain, RBD | 0.2387 | Inherited |
| Lipocalins | 0.243 | Inherited |
| SNARE-like | 0.2486 | Inherited |
| Cation efflux protein transmembrane domain-like | 0.3116 | Inherited |
| PX domain | 0.3116 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.3168 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.3558 | Inherited |
| RNI-like | 0.3715 | Inherited |
| FKBP-like | 0.3869 | Inherited |
| HD-domain/PDEase-like | 0.3869 | Inherited |
| Class II aaRS and biotin synthetases | 0.3977 | Inherited |
| Hect, E3 ligase catalytic domain | 0.4309 | Inherited |
| PRTase-like | 0.4309 | Inherited |
| Myosin rod fragments | 0.4309 | Inherited |
| DHS-like NAD/FAD-binding domain | 0.4309 | Inherited |
| Galactose-binding domain-like | 0.4508 | Inherited |
| SH2 domain | 0.452 | Inherited |
| Cystine-knot cytokines | 0.4624 | Inherited |
| Sm-like ribonucleoproteins | 0.4624 | Inherited |
| Voltage-gated potassium channels | 0.4761 | Inherited |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0.479 | Inherited |
| Calpain large subunit, middle domain (domain III) | 0.479 | Inherited |
| Riboflavin synthase domain-like | 0.479 | Inherited |
| WW domain | 0.4964 | Inherited |
| UBC-like | 0.4982 | Inherited |
| SAM/Pointed domain | 0.4995 | Inherited |
| Protein kinase-like (PK-like) | 0.5038 | Inherited |
| Seven-hairpin glycosidases | 0.5337 | Inherited |
| Multidrug resistance efflux transporter EmrE | 0.5352 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.555 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.586 | Inherited |
| Di-copper centre-containing domain | 0.5896 | Inherited |
| KA1-like | 0.5896 | Inherited |
| HIT/MYND zinc finger-like | 0.6102 | Inherited |
| GST C-terminal domain-like | 0.637 | Inherited |
| DNase I-like | 0.6528 | Inherited |
| 4Fe-4S ferredoxins | 0.6557 | Inherited |
| Frizzled cysteine-rich domain | 0.6557 | Inherited |
| S15/NS1 RNA-binding domain | 0.6557 | Inherited |
| alpha/beta-Hydrolases | 0.6764 | Inherited |
| Fibronectin type III | 0.7107 | Inherited |
| MIT domain | 0.728 | Inherited |
| ADC-like | 0.728 | Inherited |
| Clavaminate synthase-like | 0.7715 | Inherited |
| NAD kinase/diacylglycerol kinase-like | 0.7839 | Inherited |
| CoA-dependent acyltransferases | 0.79 | Inherited |
| Cyclophilin-like | 0.79 | Inherited |
| EF-hand | 0.8057 | Inherited |
| SNF-like | 0.8213 | Inherited |
| Leucine zipper domain | 0.8249 | Inherited |
| Eukaryotic type KH-domain (KH-domain type I) | 0.8315 | Inherited |
| GTPase activation domain, GAP | 0.8315 | Inherited |
| Ubiquitin-like | 0.8319 | Inherited |
| Thioredoxin-like | 0.8443 | Inherited |
| Ribonuclease H-like | 0.8672 | Inherited |
| Immunoglobulin | 0.8729 | Inherited |
| p53-like transcription factors | 0.876 | Inherited |
| Nucleic acid-binding proteins | 0.8805 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.8863 | Inherited |
| MFS general substrate transporter | 0.895 | Inherited |
| FYVE/PHD zinc finger | 0.9003 | Inherited |
| Nucleotide-diphospho-sugar transferases | 0.9025 | Inherited |
| HAD-like | 0.9096 | Inherited |
| Ribonuclease PH domain 2-like | 0.9123 | Inherited |
| Saposin | 0.9346 | Inherited |
| Periplasmic binding protein-like I | 0.9362 | Inherited |
| FAD/NAD(P)-binding domain | 0.9362 | Inherited |
| PLP-dependent transferases | 0.9425 | Inherited |
| Nucleotide cyclase | 0.9491 | Inherited |
| Ribosomal protein S5 domain 2-like | 0.9582 | Inherited |
| SET domain | 0.9655 | Inherited |
| PAZ domain | 0.9724 | Inherited |
| Ligand-binding domain in the NO signalling and Golgi transport | 0.9868 | Inherited |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.9913 | Inherited |
| Acyl-CoA dehydrogenase NM domain-like | 0.9913 | Inherited |
| Nucleotidylyl transferase | 0.9913 | Inherited |
| Translation proteins SH3-like domain | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| UBA-like | 1 | Inherited |
| dsRNA-binding domain-like | 1 | Inherited |
| Nuclear receptor ligand-binding domain | 1 | Inherited |
| B-box zinc-binding domain | 1 | Inherited |
| Insulin-like | 1 | Inherited |
| DNA/RNA polymerases | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| Snake toxin-like | 1 | Inherited |
| F-box domain | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| PapD-like | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | DIRECT |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.01495 | INHERITED FROM: RNAi response variant || chemical response variant || metal response variant || cadmium response variant || RNAi resistant || colchicine hypersensitive || chemical hypersensitive || cadmium hypersensitive |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.08858 | INHERITED FROM: positive chemotaxis defective || aqueous chemosensory response variant || ivermectin resistant || antihelmintic response variant || ivermectin response variant || aldicarb response variant || organism temperature response variant || chemotaxis variant || pattern of transgene expression variant || gene expression variant |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.1009 | INHERITED FROM: organism UV response variant || sick || organism stress response variant || organism environmental stimulus response variant |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1119 | INHERITED FROM: drug hypersensitive || lipid composition variant || nicotine hypersensitive |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1119 | INHERITED FROM: bromide chemotaxis defective || iodide chemotaxis defective || aqueous chemosensory response variant || alkaline pH chemotaxis variant || lithium chemotaxis defective || AWC odorant chemotaxis defective || AWC odorant chemotaxis variant || iodide chemotaxis variant || magnesium chemotaxis defective || chemical response variant || positive chemotaxis variant || anion positive chemotaxis variant || anion positive chemotaxis defective || bromide chemotaxis variant || benzaldehyde chemotaxis variant || cation positive chemotaxis defective || cation positive chemotaxis variant || chemotaxis variant || chemosensory response variant |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.1143 | INHERITED FROM: cadmium response variant || cadmium hypersensitive |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.1772 | INHERITED FROM: protein protein interaction variant || protein phosphorylation increased || mRNA levels increased || protein phosphorylation variant || mRNA levels reduced || proteasome core activity variant || transgene expression variant || protein aggregation variant |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2044 | INHERITED FROM: cadmium response variant || cadmium hypersensitive |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2221 | INHERITED FROM: drug hypersensitive || nicotine hypersensitive || organism environmental stimulus response variant |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2221 | INHERITED FROM: lipid metabolism variant || fat content variant |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.2785 | INHERITED FROM: positive chemotaxis defective || aqueous chemosensory response variant || aqueous positive chemotaxis defective || positive chemotaxis variant || ivermectin resistant || osmotic avoidance variant || chemical resistant || aqueous positive chemotaxis variant || mechanosensation variant || ivermectin response variant || odorant chemosensory response variant || drug resistant || chemotaxis variant || negative chemotaxis variant || pesticide response variant |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.2785 | INHERITED FROM: protein protein interaction variant || protein interaction variant || protein aggregation variant || pattern of transgene expression variant |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3116 | INHERITED FROM: drug response variant || acetylcholinesterase inhibitor response variant || aldicarb response variant |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3558 | INHERITED FROM: drug response variant || selenium response variant || sodium chloride chemotaxis variant || DMPP response variant || AWC odorant chemotaxis variant || chemical response variant || positive chemotaxis variant || chemical resistant || mechanosensation variant || nicotine resistant || slowing response on food variant || cholinergic agonist resistant || antihelmintic response variant || thermosensory behavior variant || DMPP resistant || benzaldehyde chemotaxis variant || hypoosmotic shock hypersensitive || organism environmental stimulus response variant || thermotaxis variant || chemosensory response variant |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.369 | INHERITED FROM: late larval arrest || organism metabolism processing variant || starvation induced apoptosis variant || organism starvation response variant || gene expression variant |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4294 | INHERITED FROM: organism metabolism processing variant || protein expression reduced || protein expression variant |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.4697 | INHERITED FROM: enzyme activity variant || organism heat hypersensitive || paraquat response variant || organism stress response variant || metal response variant || enzyme activity reduced || organism electrophilic stress hypersensitive || cadmium hypersensitive || organism environmental stimulus response variant |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0.5337 | INHERITED FROM: RNAi response variant || RNA expression variant || 21U RNA expression variant || gene expression variant || maintenance of gene silencing variant |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5337 | INHERITED FROM: protein expression reduced |
51045,51045
51045 - WW domain
51045 - WW domain | 0.5896 | INHERITED FROM: transgene expression variant |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.6557 | INHERITED FROM: organism UV response variant || organism UV hypersensitive || organism stress response variant |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0.6557 | INHERITED FROM: response to bacteria variant || avoids bacterial lawn || transgene expression increased |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.6592 | INHERITED FROM: protein expression reduced |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.728 | INHERITED FROM: protein expression reduced || level of protein expression variant || protein expression variant |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.79 | INHERITED FROM: growth rate variant || protein degradation variant |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.817 | INHERITED FROM: growth rate variant || protein degradation variant |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.8238 | INHERITED FROM: SDS sensitive dauer |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.9123 | INHERITED FROM: early larval arrest |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9139 | INHERITED FROM: chemical resistant || drug resistant |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.9409 | INHERITED FROM: lipid metabolism variant || fat content variant |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.9409 | INHERITED FROM: protein protein interaction variant || protein interaction variant || protein aggregation variant |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.9913 | INHERITED FROM: ascaroside biosynthesis variant || organism metabolism processing variant || ascaroside biosynthesis defective || lipid metabolism variant |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | INHERITED FROM: pathogen susceptibility increased || pathogen induced death increased |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || protein interaction variant || protein aggregation variant |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || protein interaction variant || protein aggregation variant |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
47741,56176
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
54665,56003
54665 - CO dehydrogenase molybdoprotein N-domain-like
56003 - Molybdenum cofactor-binding domain | 0 | Direct |
57362,57362
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
49742,49742
49742 - PHM/PNGase F
49742 - PHM/PNGase F | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
50978,50998
50978 - WD40 repeat-like
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
81324,81296
81324 - Voltage-gated potassium channels
81296 - E set domains | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
144232,82199
144232 - HIT/MYND zinc finger-like
82199 - SET domain | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
68923,53795
68923 - PEP carboxykinase N-terminal domain
53795 - PEP carboxykinase-like | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
81324,81327
81324 - Voltage-gated potassium channels
81327 - Small-conductance potassium channel | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
47576,47576
47576 - Calponin-homology domain, CH-domain
47576 - Calponin-homology domain, CH-domain | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
141739,141739
141739 - MFPT repeat-like
141739 - MFPT repeat-like | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
161093,161093
161093 - MgtE membrane domain-like
161093 - MgtE membrane domain-like | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
55394,55394
55394 - Bactericidal permeability-increasing protein, BPI
55394 - Bactericidal permeability-increasing protein, BPI | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
57903,82199
57903 - FYVE/PHD zinc finger
82199 - SET domain | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48179,48179
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
48431,56968
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
52540,81271
52540 - P-loop containing nucleoside triphosphate hydrolases
81271 - TGS-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
54292,47741
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
90123,52540
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.01495 | Inherited |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0.08858 | Inherited |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.1009 | Inherited |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0.1119 | Inherited |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0.1119 | Inherited |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0.1143 | Inherited |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.1772 | Inherited |
56436,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.2044 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.2221 | Inherited |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.2221 | Inherited |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.2785 | Inherited |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.2785 | Inherited |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.3116 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.3558 | Inherited |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.369 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4294 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.4697 | Inherited |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0.5337 | Inherited |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0.5337 | Inherited |
51045,51045
51045 - WW domain
51045 - WW domain | 0.5896 | Inherited |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.6557 | Inherited |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0.6557 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.6592 | Inherited |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.728 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.79 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.817 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.8238 | Inherited |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0.9123 | Inherited |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9139 | Inherited |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.9409 | Inherited |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0.9409 | Inherited |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.9913 | Inherited |
53300,56436
53300 - vWA-like
56436 - C-type lectin-like | 1 | Inherited |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 1 | Inherited |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 1 | Inherited |
(show details)
Supra-domains annotated to this WP term (Not in SPWP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | DIRECT |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1257 | INHERITED FROM: drug hypersensitive || lipid composition variant || nicotine hypersensitive |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.3403 | INHERITED FROM: cadmium response variant || cadmium hypersensitive |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3477 | INHERITED FROM: protein protein interaction variant || protein interaction variant || protein aggregation variant || pattern of transgene expression variant |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.3477 | INHERITED FROM: protein expression reduced |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4309 | INHERITED FROM: organism metabolism processing variant || protein expression reduced || protein degradation variant || level of protein expression variant || protein expression variant |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8268 | INHERITED FROM: protein protein interaction variant || transgene subcellular localization variant || protein interaction variant || protein aggregation variant || pattern of transgene expression variant |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9346 | INHERITED FROM: growth rate variant || protein degradation variant |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.9868 | INHERITED FROM: growth rate variant || protein degradation variant |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56436,49854,49854
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51735,48179,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
57414,57414,57414
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like
57414 - Hairpin loop containing domain-like | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0 | Direct |
57362,57362,57362
57362 - BPTI-like
57362 - BPTI-like
57362 - BPTI-like | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
55973,55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
54292,47741,56176
54292 - 2Fe-2S ferredoxin-like
47741 - CO dehydrogenase ISP C-domain like
56176 - FAD-binding/transporter-associated domain-like | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56968,48431,56968
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
57567,57567,57567
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors
57567 - Serine protease inhibitors | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0.1257 | Inherited |
56436,56436,49854
56436 - C-type lectin-like
56436 - C-type lectin-like
49854 - Spermadhesin, CUB domain | 0.3403 | Inherited |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0.3477 | Inherited |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0.3477 | Inherited |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4309 | Inherited |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.8268 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9346 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.9868 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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