Worm Phenotype (WP): reproductive system morphology variant

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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)

+ + + 3: Variant [WBPhenotype:0000886] <2>

+ + 2: morphology variant [WBPhenotype:0000520] <5> (443|528) (444|229|63)

+ 1: organ system morphology variant [WBPhenotype:0000534] <9> (99|104) (101|47|17)

0: reproductive system morphology variant [WBPhenotype:0000605] <5> (49|49) (50|17|6)

- 1: gonad morphology variant [WBPhenotype:0001355] <10> (29|29) (29|9|2)

- 1: hermaphrodite reproductive system morphology variant [WBPhenotype:0001335] <3> (22|22) (24|7|2)

- 1: cloacal morphology variant [WBPhenotype:0000908] <2> (0|0) (0|0|0)

- 1: connection of gonad variant [WBPhenotype:0000665] (0|0) (0|0|0)

- 1: male reproductive system morphology variant [WBPhenotype:0001306] (0|0) (0|0|0)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP term	FDR (all)	Annotation (direct or inherited)
Ribosomal proteins S24e, L23 and L15e	0	Direct
GroEL-intermediate domain like	0	Direct
GroEL equatorial domain-like	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
14-3-3 protein	0	Direct
Nop domain	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
GroEL apical domain-like	0.000000001576	Direct
Multidrug efflux transporter AcrB transmembrane domain	0.000003046	Direct
HMG-box	0.00002457	Direct
Retrovirus zinc finger-like domains	0.00003043	Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	0.00008816	Direct
Sm-like ribonucleoproteins	0.0002007	Direct
RNA-binding domain, RBD	0.0002511	Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase	0.0003316	Direct
"Winged helix" DNA-binding domain	0.0004213	Direct
Heat shock protein 70kD (HSP70), peptide-binding domain	0.0004279	Direct
GINS helical bundle-like	0.0005189	Direct
RBP11-like subunits of RNA polymerase	0.0005189	Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain	0.0009285	Direct
Cullin homology domain	0.0009944	Direct
Zn-binding ribosomal proteins	0.0009944	Direct
S15/NS1 RNA-binding domain	0.002173	Inherited
Class II aaRS ABD-related	0.002277	Inherited
Nucleic acid-binding proteins	0.002498	Inherited
Translation proteins	0.003405	Inherited
L30e-like	0.004431	Inherited
TAZ domain	0.005541	Inherited
Translational machinery components	0.005541	Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.01224	Inherited
WD40 repeat-like	0.01289	Inherited
Class II aaRS and biotin synthetases	0.01593	Inherited
Translation proteins SH3-like domain	0.02515	Inherited
ARM repeat	0.02751	Inherited
Histone-fold	0.02996	Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.03003	Inherited
Prefoldin	0.09599	Inherited
Activating enzymes of the ubiquitin-like proteins	0.09599	Inherited
P-loop containing nucleoside triphosphate hydrolases	0.1111	Inherited
Smc hinge domain	0.2279	Inherited
S-adenosylmethionine synthetase	0.2279	Inherited
Subtilisin-like	0.2279	Inherited
Nucleotide-diphospho-sugar transferases	0.4313	Inherited
Cysteine-rich domain	0.7474	Inherited
Tubulin nucleotide-binding domain-like	0.8294	Inherited
Tubulin C-terminal domain-like	0.9203	Inherited
beta-beta-alpha zinc fingers	0.923	Inherited
NAD(P)-binding Rossmann-fold domains	1	Inherited
Protein kinase-like (PK-like)	1	Inherited

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Family

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SCOP term	FDR (all)	Annotation (direct or inherited)
POU-specific domain	0	Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain	0	Direct
Nop domain	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Group II chaperonin (CCT, TRIC), intermediate domain	0	Direct
RNA-polymerase beta	0	Direct
14-3-3 protein	0	Direct
Group II chaperonin (CCT, TRIC), ATPase domain	0	Direct
MIF4G domain-like	0	Direct
Integrin domains	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Proteasome subunits	0.000000009192	Direct
Group II chaperonin (CCT, TRIC), apical domain	0.00000004955	Direct
Multidrug efflux transporter AcrB transmembrane domain	0.000007222	Direct
Laminin-type module	0.00001714	Direct
HMG-box	0.00009056	Direct
Tandem AAA-ATPase domain	0.00009363	Direct
Retrovirus zinc finger-like domains	0.00009841	Direct
Ubiquitin activating enzymes (UBA)	0.0001181	Direct
Canonical RBD	0.0001203	Direct
RecA protein-like (ATPase-domain)	0.0005927	Direct
Anticodon-binding domain	0.0007974	Direct
Glycosyl transferases group 1	0.0007974	Direct
Anticodon-binding domain of Class II aaRS	0.0007974	Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP	0.001627	Inherited
L30e/L7ae ribosomal proteins	0.003327	Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain	0.003986	Inherited
WD40-repeat	0.004921	Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain	0.02214	Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.04499	Inherited
Elongation factors	0.05067	Inherited
Forkhead DNA-binding domain	0.05525	Inherited
Actin/HSP70	0.05722	Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.06482	Inherited
Nucleosome core histones	0.06504	Inherited
Translational machinery components	0.08657	Inherited
Prefoldin	0.1349	Inherited
Cold shock DNA-binding domain-like	0.1512	Inherited
Smc hinge domain	0.2106	Inherited
Proprotein convertase P-domain	0.2106	Inherited
Subtilases	0.2106	Inherited
Chromo domain	0.2106	Inherited
S-adenosylmethionine synthetase	0.2106	Inherited
Cyclin	0.3565	Inherited
Clathrin adaptor core protein	0.4736	Inherited
I set domains	0.5063	Inherited
Tubulin, GTPase domain	0.817	Inherited
Tubulin, C-terminal domain	0.9081	Inherited
Protein kinases, catalytic subunit	1	Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term

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Supra-domain (including individual superfamily)

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Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
GroEL equatorial domain-like	0	Direct
14-3-3 protein	0	Direct
Ribosomal proteins S24e, L23 and L15e	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
GroEL-intermediate domain like	0	Direct
Nop domain	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
GroEL apical domain-like	0.000000001252	Direct
Multidrug efflux transporter AcrB transmembrane domain	0.000002473	Direct
HMG-box	0.00002005	Direct
Retrovirus zinc finger-like domains	0.00002484	Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	0.0000722	Direct
Sm-like ribonucleoproteins	0.0001648	Direct
RNA-binding domain, RBD	0.0002065	Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase	0.0002733	Direct
"Winged helix" DNA-binding domain	0.0003479	Direct
Heat shock protein 70kD (HSP70), peptide-binding domain	0.0003533	Direct
GINS helical bundle-like	0.0004294	Direct
RBP11-like subunits of RNA polymerase	0.0004294	Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain	0.0007724	Direct
Zn-binding ribosomal proteins	0.0008277	Direct
Cullin homology domain	0.0008277	Direct
S15/NS1 RNA-binding domain	0.001825	Inherited
Class II aaRS ABD-related	0.001914	Inherited
Nucleic acid-binding proteins	0.002103	Inherited
Translation proteins	0.002879	Inherited
L30e-like	0.003758	Inherited
Translational machinery components	0.004713	Inherited
TAZ domain	0.004713	Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.01056	Inherited
WD40 repeat-like	0.01113	Inherited
Class II aaRS and biotin synthetases	0.01381	Inherited
Translation proteins SH3-like domain	0.02199	Inherited
ARM repeat	0.02411	Inherited
Histone-fold	0.0263	Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.02636	Inherited
Chromo domain-like	0.05506	Inherited
Prefoldin	0.08657	Inherited
Activating enzymes of the ubiquitin-like proteins	0.08657	Inherited
P-loop containing nucleoside triphosphate hydrolases	0.1005	Inherited
S-adenosylmethionine synthetase	0.2108	Inherited
Subtilisin-like	0.2108	Inherited
Smc hinge domain	0.2108	Inherited
Nucleotide-diphospho-sugar transferases	0.4105	Inherited
Cysteine-rich domain	0.7276	Inherited
Tubulin nucleotide-binding domain-like	0.8116	Inherited
Tubulin C-terminal domain-like	0.9056	Inherited
beta-beta-alpha zinc fingers	0.9085	Inherited
Protein kinase-like (PK-like)	1	Inherited
NAD(P)-binding Rossmann-fold domains	1	Inherited

(show details)

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like	0	Direct
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0	Direct
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain	0.0001356	Direct
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain	0.0003533	Direct
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C	0.0004294	Direct
55550,50044 55550 - SH2 domain 50044 - SH3-domain	0.0004294	Direct
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like	0.0008277	Direct
50249,55681 50249 - Nucleic acid-binding proteins 55681 - Class II aaRS and biotin synthetases	0.001825	Inherited
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.009564	Inherited
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins	0.01843	Inherited
48371,48371 48371 - ARM repeat 48371 - ARM repeat	0.02199	Inherited
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.02636	Inherited
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin	0.2108	Inherited
55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase	0.2108	Inherited
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like	0.2108	Inherited
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like	0.8116	Inherited

(show details)

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
48371,48371,48371 48371 - ARM repeat 48371 - ARM repeat 48371 - ARM repeat	0	Direct
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0	Direct
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain	0.0001356	Direct
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain	0.0003533	Direct
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.02636	Inherited
55973,55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase	0.2108	Inherited

Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term

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Worm Phenotype (WP): reproductive system morphology variant

Superfamily

Family

Supra-domain (including individual superfamily)