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Worm Phenotype (WP): lipid metabolism variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|56)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|55)
+ 1:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
0:   lipid metabolism variant [WBPhenotype:0000725] <8>(19|27) (21|8|4)
- 1:   fat content variant [WBPhenotype:0001182] <2>(13|23) (14|5|2)
- 1:   lipid composition variant [WBPhenotype:0000138] <2>(3|1) (3|1|1)
- 1:   cholesterol depletion hypersensitive [WBPhenotype:0001766](0|0) (0|0|0)
- 1:   cholesterol depletion resistant [WBPhenotype:0002363](0|0) (0|0|0)
- 1:   lipid hydrolysis regulation variant [WBPhenotype:0001844](0|0) (0|0|0)
- 1:   lipid modification variant [WBPhenotype:0001845](0|0) (0|0|0)
- 1:   lipid synthesis defective [WBPhenotype:0000383](0|0) (0|0|0)
- 1:   lipid synthesis increased [WBPhenotype:0001742](1|1) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
Oxysterol-binding protein-like0Direct
Acetyl-CoA synthetase-like0.0000000001517Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.00000000109Direct
Acyl-CoA dehydrogenase NM domain-like0.00000000109Direct
Lipocalins0.00000002799Direct
Thiolase-like0.000003517Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0.00001789Direct
PapD-like0.00002589Direct
ClpP/crotonase0.0001378Direct
Periplasmic binding protein-like II0.0004941Direct
Nuclear receptor ligand-binding domain0.001109Inherited
SMAD MH1 domain0.00201Inherited
Snake toxin-like0.005527Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.01191Inherited
SMAD/FHA domain0.0442Inherited
Protein kinase-like (PK-like)0.131Inherited
Calcium ATPase, transmembrane domain M0.1771Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.1771Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Heme-dependent catalases0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Oxysterol-binding protein0Direct
Fatty acid binding protein-like0.00000000000004489Direct
Acetyl-CoA synthetase-like0.0000000002403Direct
acyl-CoA oxidase C-terminal domains0.00000002403Direct
acyl-CoA oxidase N-terminal domains0.00000002403Direct
Gastric lipase0.0000001772Direct
Thiolase-related0.000001529Direct
HCDH C-domain-like0.000001529Direct
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.000007227Direct
Choline/Carnitine O-acyltransferase0.000008873Direct
MSP-like0.000009948Direct
Crotonase-like0.00001128Direct
6-phosphogluconate dehydrogenase-like, N-terminal domain0.00001128Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.00003245Direct
Bacterial lipase0.00005984Direct
Phosphate binding protein-like0.0003159Direct
Nuclear receptor ligand-binding domain0.00141Inherited
SMAD MH1 domain0.001414Inherited
SMAD domain0.004062Inherited
Nuclear receptor0.005566Inherited
G proteins0.01283Inherited
GABA-aminotransferase-like0.01626Inherited
PLC-like (P variant)0.02792Inherited
Protein kinases, catalytic subunit0.7211Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
Oxysterol-binding protein-like0Direct
Acetyl-CoA synthetase-like0.0000000001201Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.0000000008656Direct
Acyl-CoA dehydrogenase NM domain-like0.0000000008656Direct
Lipocalins0.00000002236Direct
Thiolase-like0.000002855Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0.00001459Direct
PapD-like0.00002114Direct
ClpP/crotonase0.000113Direct
Periplasmic binding protein-like II0.000409Direct
Nuclear receptor ligand-binding domain0.0009236Direct
CoA-dependent acyltransferases0.0009461Direct
Insulin-like0.001386Inherited
SMAD MH1 domain0.001685Inherited
Snake toxin-like0.004701Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.01026Inherited
SMAD/FHA domain0.03905Inherited
Protein kinase-like (PK-like)0.1191Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.1626Inherited
Calcium ATPase, transmembrane domain M0.1626Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    48179,48179
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.0000000008656Direct
    47203,47203
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.00000001007Direct
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0.00001459Direct
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0.00007331Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.1626Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51735,48179,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56645,47203,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.00000001007Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.1232Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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