Worm Phenotype (WP): apoptosis variant

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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP term	FDR (all)	Annotation (direct or inherited)
PX domain	0	Direct
RBP11-like subunits of RNA polymerase	0	Direct
DLC	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
VPS9 domain	0	Direct
Subdomain of clathrin and coatomer appendage domain	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Clathrin adaptor appendage domain	0	Direct
Skp1 dimerisation domain-like	0.0000000000000277	Direct
Cullin homology domain	0.00000003628	Direct
GroEL apical domain-like	0.0000001015	Direct
PH domain-like	0.0000002632	Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase	0.0000004887	Direct
GroEL-intermediate domain like	0.00000109	Direct
GroEL equatorial domain-like	0.00000109	Direct
Cullin repeat-like	0.00000109	Direct
ENTH/VHS domain	0.000004847	Direct
Histone-fold	0.000009257	Direct
Sm-like ribonucleoproteins	0.00005108	Direct
Nucleic acid-binding proteins	0.00005179	Direct
SH3-domain	0.00005179	Direct
"Winged helix" DNA-binding domain	0.00005899	Direct
5' to 3' exonuclease, C-terminal subdomain	0.00008403	Direct
Integrin domains	0.00008403	Direct
BAR/IMD domain-like	0.0002176	Direct
Activating enzymes of the ubiquitin-like proteins	0.0002675	Direct
Tubby C-terminal domain-like	0.0003732	Direct
Cupredoxins	0.0003732	Direct
DEATH domain	0.0005473	Direct
SNARE-like	0.0007132	Direct
Sec1/munc18-like (SM) proteins	0.001004	Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	0.001004	Inherited
Metal cation-transporting ATPase, ATP-binding domain N	0.001291	Inherited
Lamin A/C globular tail domain	0.001675	Inherited
Calcium ATPase, transmembrane domain M	0.001744	Inherited
HLH, helix-loop-helix DNA-binding domain	0.003192	Inherited
PIN domain-like	0.003829	Inherited
Calcium ATPase, transduction domain A	0.005544	Inherited
Hect, E3 ligase catalytic domain	0.006245	Inherited
Intermediate filament protein, coiled coil region	0.01361	Inherited
Chromo domain-like	0.09645	Inherited
POZ domain	0.1031	Inherited
ARM repeat	0.1362	Inherited
Saposin	0.1746	Inherited
RNA-binding domain, RBD	0.326	Inherited
PLP-dependent transferases	0.4984	Inherited
S-adenosyl-L-methionine-dependent methyltransferases	0.5659	Inherited
SET domain	0.7664	Inherited
FYVE/PHD zinc finger	0.8364	Inherited
Metallo-dependent phosphatases	0.8797	Inherited
Protein kinase-like (PK-like)	0.9837	Inherited

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Family

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SCOP term	FDR (all)	Annotation (direct or inherited)
PX domain	0	Direct
Cullin repeat	0	Direct
DLC	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Myotubularin-like phosphatases	0	Direct
SCF ubiquitin ligase complex WHB domain	0	Direct
Group II chaperonin (CCT, TRIC), intermediate domain	0	Direct
RNA-polymerase beta	0	Direct
Phoshoinositide 3-kinase (PI3K) helical domain	0	Direct
Integrin domains	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Arginine methyltransferase	0	Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain	3.134e-16	Direct
Skp1 dimerisation domain-like	0.00000000000009845	Direct
Group II chaperonin (CCT, TRIC), apical domain	0.00000007055	Direct
Cullin homology domain	0.00000009769	Direct
Group II chaperonin (CCT, TRIC), ATPase domain	0.0000007061	Direct
RecA protein-like (ATPase-domain)	0.000001094	Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain	0.000002869	Direct
G proteins	0.00002576	Direct
Nucleosome core histones	0.00003147	Direct
BTB/POZ domain	0.00006687	Direct
Ephrin ectodomain	0.0001313	Direct
5' to 3' exonuclease catalytic domain	0.0001313	Direct
5' to 3' exonuclease, C-terminal subdomain	0.0001313	Direct
Cold shock DNA-binding domain-like	0.0001683	Direct
Clathrin adaptor core protein	0.000203	Direct
SH3-domain	0.0003216	Direct
BAR domain	0.0005799	Direct
Ubiquitin activating enzymes (UBA)	0.0005799	Direct
Phosphotyrosine-binding domain (PTB)	0.0009215	Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP	0.0009215	Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	0.001553	Inherited
Sec1/munc18-like (SM) proteins	0.001553	Inherited
Armadillo repeat	0.004632	Inherited
Translational machinery components	0.005889	Inherited
HLH, helix-loop-helix DNA-binding domain	0.008571	Inherited
Hect, E3 ligase catalytic domain	0.009599	Inherited
Proteasome subunits	0.00968	Inherited
Calcium ATPase, transduction domain A	0.01083	Inherited
Intermediate filament protein, coiled coil region	0.0208	Inherited
Canonical RBD	0.4177	Inherited
Histone lysine methyltransferases	0.8102	Inherited
Protein kinases, catalytic subunit	1	Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term

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Supra-domain (including individual superfamily)

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Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
Clathrin adaptor appendage domain	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
RBP11-like subunits of RNA polymerase	0	Direct
VPS9 domain	0	Direct
Subdomain of clathrin and coatomer appendage domain	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
DLC	0	Direct
PX domain	0	Direct
Skp1 dimerisation domain-like	0.00000000000002173	Direct
Cullin homology domain	0.00000002901	Direct
GroEL apical domain-like	0.00000008128	Direct
PH domain-like	0.0000002116	Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase	0.0000003937	Direct
GroEL equatorial domain-like	0.0000008809	Direct
GroEL-intermediate domain like	0.0000008809	Direct
Cullin repeat-like	0.0000008809	Direct
ENTH/VHS domain	0.000003939	Direct
Histone-fold	0.000007531	Direct
Sm-like ribonucleoproteins	0.00004179	Direct
SH3-domain	0.00004238	Direct
Nucleic acid-binding proteins	0.00004238	Direct
"Winged helix" DNA-binding domain	0.00004826	Direct
Integrin domains	0.00006881	Direct
5' to 3' exonuclease, C-terminal subdomain	0.00006881	Direct
BAR/IMD domain-like	0.0001789	Direct
Activating enzymes of the ubiquitin-like proteins	0.0002202	Direct
Tubby C-terminal domain-like	0.0003078	Direct
Cupredoxins	0.0003078	Direct
DEATH domain	0.0004532	Direct
SNARE-like	0.0005919	Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	0.0008357	Direct
Sec1/munc18-like (SM) proteins	0.0008357	Direct
Metal cation-transporting ATPase, ATP-binding domain N	0.001077	Inherited
Lamin A/C globular tail domain	0.001401	Inherited
Calcium ATPase, transmembrane domain M	0.001459	Inherited
HLH, helix-loop-helix DNA-binding domain	0.002696	Inherited
PIN domain-like	0.003243	Inherited
Calcium ATPase, transduction domain A	0.004715	Inherited
Hect, E3 ligase catalytic domain	0.005322	Inherited
Intermediate filament protein, coiled coil region	0.01177	Inherited
Chromo domain-like	0.08701	Inherited
POZ domain	0.09316	Inherited
ARM repeat	0.124	Inherited
Saposin	0.1602	Inherited
RNA-binding domain, RBD	0.3065	Inherited
PLP-dependent transferases	0.4767	Inherited
S-adenosyl-L-methionine-dependent methyltransferases	0.5441	Inherited
SET domain	0.7473	Inherited
FYVE/PHD zinc finger	0.8189	Inherited
Metallo-dependent phosphatases	0.8638	Inherited
Protein kinase-like (PK-like)	0.9724	Inherited

(show details)

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat	0	Direct
74788,75632 74788 - Cullin repeat-like 75632 - Cullin homology domain	0	Direct
75632,46785 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain	0	Direct
49348,55711 49348 - Clathrin adaptor appendage domain 55711 - Subdomain of clathrin and coatomer appendage domain	0	Direct
54695,81382 54695 - POZ domain 81382 - Skp1 dimerisation domain-like	0.0000000000000623	Direct
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like	0.0000008809	Direct
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0.0000008809	Direct
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like)	0.0003078	Direct
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like	0.001077	Inherited
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin	0.007789	Inherited
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD	0.02783	Inherited

(show details)

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like)	0	Direct
74788,75632,46785 74788 - Cullin repeat-like 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain	0	Direct
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0.0000008809	Direct
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M	0.0007767	Direct
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module	0.01177	Inherited

Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term

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Worm Phenotype (WP): apoptosis variant

Superfamily

Family

Supra-domain (including individual superfamily)