Worm Phenotype (WP): germ cell differentiation variant

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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)

+ + + + + 5: Variant [WBPhenotype:0000886] <2>

+ + + + 4: physiology variant [WBPhenotype:0000519] <14> (510|587) (510|248|68)

+ + + 3: development variant [WBPhenotype:0000518] <6> (508|585) (508|248|68)

+ + 2: cell development variant [WBPhenotype:0000529] <17> (119|124) (119|47|12)

+ 1: gametogenesis variant [WBPhenotype:0000774] <2> (57|57) (58|22|4)

0: germ cell differentiation variant [WBPhenotype:0000894] <3> (38|40) (38|15|2)

- 1: spermatogenesis variant [WBPhenotype:0000670] <8> (1|1) (1|0|0)

- 1: oogenesis variant [WBPhenotype:0000186] <5> (33|34) (33|14|2)

- 1: no differentiated gametes [WBPhenotype:0000395] <2> (7|9) (7|3|1)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP term	FDR (all)	Annotation (direct or inherited)
Helical domain of Sec23/24	0	Direct
GroEL-intermediate domain like	0	Direct
GroEL equatorial domain-like	0	Direct
C-terminal, gelsolin-like domain of Sec23/24	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
14-3-3 protein	0	Direct
Zn-finger domain of Sec23/24	0	Direct
Skp1 dimerisation domain-like	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
GroEL apical domain-like	0.000000000006658	Direct
Class II aaRS and biotin synthetases	0.000007395	Direct
Translation proteins SH3-like domain	0.00001138	Direct
beta-sandwich domain of Sec23/24	0.00006295	Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.00009459	Direct
Class II aaRS ABD-related	0.0001898	Direct
F1F0 ATP synthase subunit C	0.000281	Direct
Ribosomal proteins S24e, L23 and L15e	0.000281	Direct
S15/NS1 RNA-binding domain	0.000281	Direct
L30e-like	0.000391	Direct
Translation proteins	0.0004391	Direct
SNARE-like	0.0004813	Direct
Sec1/munc18-like (SM) proteins	0.0007614	Direct
Translational machinery components	0.0007614	Direct
ACP-like	0.001615	Inherited
Cullin homology domain	0.001615	Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.004836	Inherited
Ribosomal protein S5 domain 2-like	0.04212	Inherited
Nucleic acid-binding proteins	0.09891	Inherited
CCCH zinc finger	0.2823	Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	0.3755	Inherited
Sm-like ribonucleoproteins	0.3822	Inherited
Nucleotidylyl transferase	0.3858	Inherited
Smc hinge domain	0.723	Inherited
PAZ domain	0.8751	Inherited
Protein kinase-like (PK-like)	0.9403	Inherited
POZ domain	0.9576	Inherited
Histone-fold	1	Inherited
"Winged helix" DNA-binding domain	1	Inherited

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Family

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SCOP term	FDR (all)	Annotation (direct or inherited)
beta-sandwich domain of Sec23/24	0	Direct
Helical domain of Sec23/24	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Zn-finger domain of Sec23/24	0	Direct
Group II chaperonin (CCT, TRIC), intermediate domain	0	Direct
14-3-3 protein	0	Direct
Trunk domain of Sec23/24	0	Direct
Group II chaperonin (CCT, TRIC), ATPase domain	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
C-terminal, gelsolin-like domain of Sec23/24	0	Direct
Skp1 dimerisation domain-like	6.263e-16	Direct
Group II chaperonin (CCT, TRIC), apical domain	0.0000000003349	Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain	0.000007593	Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain	0.00004171	Direct
Anticodon-binding domain	0.00009214	Direct
Anticodon-binding domain of Class II aaRS	0.00009214	Direct
Translational machinery components	0.0003192	Direct
L30e/L7ae ribosomal proteins	0.0004101	Direct
F1F0 ATP synthase subunit C	0.0004101	Direct
Cold shock DNA-binding domain-like	0.0005624	Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.001192	Inherited
G proteins	0.001336	Inherited
Clathrin adaptor core protein	0.002347	Inherited
Cullin homology domain	0.002347	Inherited
Elongation factors	0.004005	Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.007001	Inherited
Nitrogenase iron protein-like	0.0154	Inherited
Pumilio repeat	0.07226	Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain	0.07226	Inherited
Ubiquitin-related	0.07226	Inherited
RecA protein-like (ATPase-domain)	0.1634	Inherited
CCCH zinc finger	0.3059	Inherited
Cyclin	0.3059	Inherited
BTB/POZ domain	0.3686	Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP	0.4208	Inherited
Proteasome subunits	0.5058	Inherited
Smc hinge domain	0.5273	Inherited
Extended AAA-ATPase domain	0.75	Inherited
Protein kinases, catalytic subunit	0.9367	Inherited
Nucleosome core histones	1	Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term

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Supra-domain (including individual superfamily)

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Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
GroEL equatorial domain-like	0	Direct
C-terminal, gelsolin-like domain of Sec23/24	0	Direct
14-3-3 protein	0	Direct
Skp1 dimerisation domain-like	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
GroEL-intermediate domain like	0	Direct
Helical domain of Sec23/24	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Zn-finger domain of Sec23/24	0	Direct
GroEL apical domain-like	0.000000000005254	Direct
Class II aaRS and biotin synthetases	0.000006016	Direct
Translation proteins SH3-like domain	0.000009266	Direct
beta-sandwich domain of Sec23/24	0.00005149	Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.00007751	Direct
Class II aaRS ABD-related	0.0001559	Direct
F1F0 ATP synthase subunit C	0.0002313	Direct
Ribosomal proteins S24e, L23 and L15e	0.0002313	Direct
S15/NS1 RNA-binding domain	0.0002313	Direct
L30e-like	0.0003225	Direct
Translation proteins	0.0003628	Direct
SNARE-like	0.0003982	Direct
Translational machinery components	0.0006327	Direct
Sec1/munc18-like (SM) proteins	0.0006327	Direct
Cullin homology domain	0.001349	Inherited
ACP-like	0.001349	Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.004107	Inherited
Ribosomal protein S5 domain 2-like	0.03718	Inherited
Nucleic acid-binding proteins	0.08929	Inherited
CCCH zinc finger	0.2638	Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	0.3552	Inherited
Sm-like ribonucleoproteins	0.3617	Inherited
Nucleotidylyl transferase	0.3653	Inherited
Smc hinge domain	0.7026	Inherited
PAZ domain	0.8591	Inherited
Protein kinase-like (PK-like)	0.9267	Inherited
POZ domain	0.9444	Inherited
"Winged helix" DNA-binding domain	1	Inherited
Histone-fold	1	Inherited

(show details)

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like	0	Direct
81811,82754 81811 - Helical domain of Sec23/24 82754 - C-terminal, gelsolin-like domain of Sec23/24	0	Direct
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0	Direct
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
82919,53300 82919 - Zn-finger domain of Sec23/24 53300 - vWA-like	0	Direct
54695,81382 54695 - POZ domain 81382 - Skp1 dimerisation domain-like	3.517e-16	Direct
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C	0.00005149	Direct
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.0000637	Direct
50249,55681 50249 - Nucleic acid-binding proteins 55681 - Class II aaRS and biotin synthetases	0.0002313	Direct
48371,48371 48371 - ARM repeat 48371 - ARM repeat	0.000915	Direct
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins	0.00131	Inherited
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like	0.003459	Inherited
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.004107	Inherited
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin	0.02364	Inherited
90229,90229 90229 - CCCH zinc finger 90229 - CCCH zinc finger	0.2175	Inherited

(show details)

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0	Direct
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.004107	Inherited

Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term

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Worm Phenotype (WP): germ cell differentiation variant

Superfamily

Family

Supra-domain (including individual superfamily)