Worm Phenotype (WP): germ cell morphology variant

(show info)

Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)

+ + + + 4: Variant [WBPhenotype:0000886] <2>

+ + + 3: morphology variant [WBPhenotype:0000520] <5> (443|528) (444|229|63)

+ + 2: cell morphology variant [WBPhenotype:0000533] <10> (104|103) (106|55|17)

+ 1: cell type morphology variant [WBPhenotype:0002108] <12> (77|76) (79|45|15)

0: germ cell morphology variant [WBPhenotype:0000900] <4> (44|41) (45|23|8)

- 1: oocyte morphology variant [WBPhenotype:0001260] <9> (27|30) (27|14|3)

- 1: germ cell compartment morphology variant [WBPhenotype:0001969] <4> (25|26) (25|10|2)

- 1: germ cell cytoplasmic morphology variant [WBPhenotype:0001300] <3> (11|8) (11|5|2)

- 1: sperm morphology variant [WBPhenotype:0000388] <1> (1|0) (1|1|1)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)

SCOP term	FDR (all)	Annotation (direct or inherited)
Helical domain of Sec23/24	0	Direct
C-terminal, gelsolin-like domain of Sec23/24	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Zn-finger domain of Sec23/24	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Sm-like ribonucleoproteins	0.00000000000835	Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	0.00000004566	Direct
Actin-like ATPase domain	0.00000005811	Direct
GroEL-intermediate domain like	0.0000000811	Direct
GroEL equatorial domain-like	0.0000000811	Direct
Class II aaRS and biotin synthetases	0.000000467	Direct
Translation proteins SH3-like domain	0.000003305	Direct
Ribosomal proteins S24e, L23 and L15e	0.00001454	Direct
Class II aaRS ABD-related	0.00002907	Direct
PLC-like phosphodiesterases	0.0001062	Direct
Annexin	0.0001597	Direct
ADC-like	0.0001597	Direct
RBP11-like subunits of RNA polymerase	0.0001597	Direct
Cdc48 domain 2-like	0.0001597	Direct
beta-sandwich domain of Sec23/24	0.0001597	Direct
Zn-binding ribosomal proteins	0.0002408	Direct
dsRNA-binding domain-like	0.0003268	Direct
Translation proteins	0.0003863	Direct
Activating enzymes of the ubiquitin-like proteins	0.0005726	Direct
F1F0 ATP synthase subunit C	0.0006954	Direct
S15/NS1 RNA-binding domain	0.0006954	Direct
L30e-like	0.001158	Inherited
Translational machinery components	0.00184	Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.003427	Inherited
ACP-like	0.003821	Inherited
Ribosomal protein S5 domain 2-like	0.009515	Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.01098	Inherited
RNA-binding domain, RBD	0.01457	Inherited
GroEL apical domain-like	0.0262	Inherited
EF-hand	0.03242	Inherited
ARM repeat	0.0342	Inherited
CCCH zinc finger	0.06581	Inherited
Nucleic acid-binding proteins	0.3296	Inherited
PDZ domain-like	0.557	Inherited
PH domain-like	0.8485	Inherited
Cysteine-rich domain	0.9276	Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)	0.9468	Inherited
SH3-domain	0.9872	Inherited
Immunoglobulin	1	Inherited

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)

SCOP term	FDR (all)	Annotation (direct or inherited)
beta-sandwich domain of Sec23/24	0	Direct
Helical domain of Sec23/24	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Zn-finger domain of Sec23/24	0	Direct
Group II chaperonin (CCT, TRIC), intermediate domain	0	Direct
Mammalian PLC	0	Direct
Trunk domain of Sec23/24	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Anticodon-binding domain of Class II aaRS	0	Direct
C-terminal, gelsolin-like domain of Sec23/24	0	Direct
Proteasome subunits	0.0000000002351	Direct
Actin/HSP70	0.000000001719	Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP	0.000000001975	Direct
Group II chaperonin (CCT, TRIC), ATPase domain	0.00000002925	Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain	0.0000004745	Direct
Pumilio repeat	0.00002384	Direct
RecA protein-like (ATPase-domain)	0.0001347	Direct
Cdc48 domain 2-like	0.000238	Direct
Annexin	0.000238	Direct
Anticodon-binding domain	0.000238	Direct
Cdc48 N-terminal domain-like	0.000238	Direct
Cold shock DNA-binding domain-like	0.0005303	Direct
Translational machinery components	0.0009807	Direct
Heat shock protein 70kD (HSP70), peptide-binding domain	0.0009807	Direct
L30e/L7ae ribosomal proteins	0.001033	Inherited
F1F0 ATP synthase subunit C	0.001033	Inherited
Canonical RBD	0.01092	Inherited
Elongation factors	0.01282	Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.01618	Inherited
Group II chaperonin (CCT, TRIC), apical domain	0.02143	Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.02418	Inherited
Extended AAA-ATPase domain	0.04471	Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain	0.05068	Inherited
CCCH zinc finger	0.05548	Inherited
G proteins	0.09968	Inherited
Laminin-type module	0.1002	Inherited
Nitrogenase iron protein-like	0.1002	Inherited
Clathrin adaptor core protein	0.1661	Inherited
PLC-like (P variant)	0.1917	Inherited
PDZ domain	0.581	Inherited
Pleckstrin-homology domain (PH domain)	0.8604	Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term

Plot tree as:

Download Newick format tree:

(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)

Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/24	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Helical domain of Sec23/24	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Zn-finger domain of Sec23/24	0	Direct
Sm-like ribonucleoproteins	0.000000000006589	Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	0.00000003653	Direct
Actin-like ATPase domain	0.00000004651	Direct
GroEL equatorial domain-like	0.00000006496	Direct
GroEL-intermediate domain like	0.00000006496	Direct
Class II aaRS and biotin synthetases	0.0000003762	Direct
Translation proteins SH3-like domain	0.000002684	Direct
Ribosomal proteins S24e, L23 and L15e	0.00001184	Direct
Class II aaRS ABD-related	0.00002373	Direct
PLC-like phosphodiesterases	0.00008699	Direct
Cdc48 domain 2-like	0.0001311	Direct
Annexin	0.0001311	Direct
RBP11-like subunits of RNA polymerase	0.0001311	Direct
beta-sandwich domain of Sec23/24	0.0001311	Direct
ADC-like	0.0001311	Direct
Zn-binding ribosomal proteins	0.0001979	Direct
dsRNA-binding domain-like	0.0002693	Direct
Translation proteins	0.0003187	Direct
Activating enzymes of the ubiquitin-like proteins	0.0004743	Direct
F1F0 ATP synthase subunit C	0.0005769	Direct
S15/NS1 RNA-binding domain	0.0005769	Direct
L30e-like	0.0009646	Direct
Heat shock protein 70kD (HSP70), peptide-binding domain	0.0009646	Direct
Translational machinery components	0.001541	Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.002899	Inherited
ACP-like	0.003237	Inherited
Ribosomal protein S5 domain 2-like	0.008174	Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.009456	Inherited
RNA-binding domain, RBD	0.01262	Inherited
GroEL apical domain-like	0.02293	Inherited
EF-hand	0.02851	Inherited
ARM repeat	0.0301	Inherited
CCCH zinc finger	0.05872	Inherited
Nucleic acid-binding proteins	0.31	Inherited
PDZ domain-like	0.5352	Inherited
PH domain-like	0.8314	Inherited
Cysteine-rich domain	0.9135	Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)	0.9334	Inherited
SH3-domain	0.9762	Inherited
Immunoglobulin	1	Inherited

(show details)

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases	0	Direct
81811,82754 81811 - Helical domain of Sec23/24 82754 - C-terminal, gelsolin-like domain of Sec23/24	0	Direct
50729,47473 50729 - PH domain-like 47473 - EF-hand	0	Direct
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases	0	Direct
51695,49562 51695 - PLC-like phosphodiesterases 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)	0	Direct
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like	0	Direct
82919,53300 82919 - Zn-finger domain of Sec23/24 53300 - vWA-like	0	Direct
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain	0.000000003337	Direct
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like	0.00000006496	Direct
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0.00000006496	Direct
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C	0.0001311	Direct
55681,52954 55681 - Class II aaRS and biotin synthetases 52954 - Class II aaRS ABD-related	0.0001311	Direct
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain	0.0004743	Direct
50249,55681 50249 - Nucleic acid-binding proteins 55681 - Class II aaRS and biotin synthetases	0.0005769	Direct
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain	0.0009646	Direct
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.003237	Inherited
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins	0.004351	Inherited
90229,90229 90229 - CCCH zinc finger 90229 - CCCH zinc finger	0.004351	Inherited
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.009456	Inherited
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD	0.06368	Inherited
48371,48371 48371 - ARM repeat 48371 - ARM repeat	0.08927	Inherited
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin	0.9692	Inherited

(show details)

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases	0	Direct
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases	0	Direct
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases	0	Direct
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0.00000006496	Direct
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain	0.0004743	Direct
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain	0.0009646	Direct
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	0.009456	Inherited
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin	0.6274	Inherited

Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term

Plot tree as:

Download Newick format tree:

(show help)

SEARCH

BROWSE

TOOLS

ABOUT

HELP

Worm Phenotype (WP): germ cell morphology variant

Superfamily

Family

Supra-domain (including individual superfamily)