Worm Phenotype (WP): level of transgene expression variant

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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)

+ + + + + + + 7: Variant [WBPhenotype:0000886] <2>

+ + + + + + 6: physiology variant [WBPhenotype:0000519] <14> (510|587) (510|248|68)

+ + + + + 5: organism physiology variant [WBPhenotype:0000576] <9> (369|431) (372|193|56)

+ + + + 4: organism homeostasis metabolism variant [WBPhenotype:0000577] <16> (361|421) (363|190|55)

+ + + 3: organism metabolism processing variant [WBPhenotype:0000027] <25> (178|190) (182|87|26)

+ + 2: gene expression variant [WBPhenotype:0000717] <11> (127|139) (131|64|20)

+ 1: transgene expression variant [WBPhenotype:0000306] <3> (82|99) (85|43|14)

0: level of transgene expression variant [WBPhenotype:0000962] <2> (36|44) (39|12|5)

- 1: transgene expression reduced [WBPhenotype:0001278] <3> (12|14) (12|2|2)

- 1: transgene expression increased [WBPhenotype:0001236] (15|22) (15|8|3)

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Superfamily

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SCOP term	FDR (all)	Annotation (direct or inherited)
F1F0 ATP synthase subunit C	0	Direct
FF domain	0	Direct
TK C-terminal domain-like	0	Direct
Cytochrome c	0	Direct
GroEL-intermediate domain like	0	Direct
GroEL equatorial domain-like	0	Direct
Heme-dependent catalase-like	0	Direct
14-3-3 protein	0	Direct
Ribosomal protein L1	0	Direct
ValRS/IleRS/LeuRS editing domain	0	Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase	0	Direct
HSP90 C-terminal domain	0	Direct
GroEL apical domain-like	0.00000001805	Direct
Homeodomain-like	0.0000001661	Direct
Glucocorticoid receptor-like (DNA-binding domain)	0.0000002882	Direct
Saposin	0.000006782	Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase	0.00003339	Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.00007662	Direct
Single hybrid motif	0.00007662	Direct
Leucine zipper domain	0.00009024	Direct
Zn-binding ribosomal proteins	0.0001928	Direct
ClpP/crotonase	0.0002057	Direct
Nuclear receptor ligand-binding domain	0.0008344	Direct
ADC-like	0.001323	Inherited
Cdc48 domain 2-like	0.001323	Inherited
Protein kinase-like (PK-like)	0.00355	Inherited
Tubby C-terminal domain-like	0.005304	Inherited
S15/NS1 RNA-binding domain	0.005304	Inherited
Nucleotidylyl transferase	0.02074	Inherited
SMAD MH1 domain	0.0524	Inherited
4Fe-4S ferredoxins	0.1542	Inherited
Frizzled cysteine-rich domain	0.1542	Inherited
S-adenosylmethionine synthetase	0.1542	Inherited
PYP-like sensor domain (PAS domain)	0.2526	Inherited
Class II aaRS ABD-related	0.3236	Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain	0.6351	Inherited

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Family

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SCOP term	FDR (all)	Annotation (direct or inherited)
CAT-like	0	Direct
Ribosomal protein L1	0	Direct
a tRNA synthase domain	0	Direct
Heat shock protein 90, HSP90, N-terminal domain	0	Direct
ValRS/IleRS/LeuRS editing domain	0	Direct
Heme-dependent catalases	0	Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase	0	Direct
FF domain	0	Direct
Hsp90 middle domain	0	Direct
Group II chaperonin (CCT, TRIC), intermediate domain	0	Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain	0	Direct
RNA-polymerase beta	0	Direct
14-3-3 protein	0	Direct
HSP90 C-terminal domain	0	Direct
Group II chaperonin (CCT, TRIC), ATPase domain	0	Direct
F1F0 ATP synthase subunit C	0	Direct
Anticodon-binding domain of Class II aaRS	0	Direct
Group II chaperonin (CCT, TRIC), apical domain	0.0000004493	Direct
Homeodomain	0.000003612	Direct
Biotinyl/lipoyl-carrier proteins and domains	0.0002192	Direct
Transforming growth factor (TGF)-beta	0.0003908	Direct
Leucine zipper domain	0.0004108	Direct
Dual specificity phosphatase-like	0.0005378	Direct
Proteasome subunits	0.0005378	Direct
Cyclin	0.0007226	Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.0008629	Direct
Cdc48 domain 2-like	0.002061	Inherited
Anticodon-binding domain	0.002061	Inherited
Biotin dependent carboxylase carboxyltransferase domain	0.002061	Inherited
MIF4G domain-like	0.002061	Inherited
Cdc48 N-terminal domain-like	0.002061	Inherited
DEP domain	0.008219	Inherited
Nuclear receptor	0.0183	Inherited
SMAD domain	0.0281	Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain	0.04806	Inherited
SMAD MH1 domain	0.04886	Inherited
Nuclear receptor ligand-binding domain	0.059	Inherited
Protein kinases, catalytic subunit	0.1193	Inherited
Frizzled cysteine-rich domain	0.1444	Inherited
S-adenosylmethionine synthetase	0.1444	Inherited
PDI-like	0.2436	Inherited
RecA protein-like (ATPase-domain)	0.2436	Inherited
PLC-like (P variant)	0.4813	Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain	0.6335	Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term

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Supra-domain (including individual superfamily)

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Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
F1F0 ATP synthase subunit C	0	Direct
GroEL equatorial domain-like	0	Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase	0	Direct
ValRS/IleRS/LeuRS editing domain	0	Direct
Heme-dependent catalase-like	0	Direct
14-3-3 protein	0	Direct
HSP90 C-terminal domain	0	Direct
Ribosomal protein L1	0	Direct
GroEL-intermediate domain like	0	Direct
FF domain	0	Direct
Cytochrome c	0	Direct
TK C-terminal domain-like	0	Direct
GroEL apical domain-like	0.00000001441	Direct
Homeodomain-like	0.0000001333	Direct
Glucocorticoid receptor-like (DNA-binding domain)	0.0000002318	Direct
Saposin	0.000005516	Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase	0.00002727	Direct
Single hybrid motif	0.0000627	Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	0.0000627	Direct
Leucine zipper domain	0.00007392	Direct
Zn-binding ribosomal proteins	0.0001583	Direct
ClpP/crotonase	0.000169	Direct
Nuclear receptor ligand-binding domain	0.000694	Direct
Cyclin-like	0.0008355	Direct
p53-like transcription factors	0.0008355	Direct
Histone-fold	0.0009359	Direct
Cdc48 domain 2-like	0.001104	Inherited
ADC-like	0.001104	Inherited
Protein kinase-like (PK-like)	0.003004	Inherited
Tubby C-terminal domain-like	0.004509	Inherited
S15/NS1 RNA-binding domain	0.004509	Inherited
Nucleotidylyl transferase	0.01806	Inherited
SMAD MH1 domain	0.0465	Inherited
S-adenosylmethionine synthetase	0.1408	Inherited
4Fe-4S ferredoxins	0.1408	Inherited
Frizzled cysteine-rich domain	0.1408	Inherited
PYP-like sensor domain (PAS domain)	0.2347	Inherited
Class II aaRS ABD-related	0.3041	Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain	0.6132	Inherited

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Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
50677,52374 50677 - ValRS/IleRS/LeuRS editing domain 52374 - Nucleotidylyl transferase	0	Direct
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like	0	Direct
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C	0	Direct
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0	Direct
52518,52922 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52922 - TK C-terminal domain-like	0	Direct
81698,81698 81698 - FF domain 81698 - FF domain	0	Direct
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases	0	Direct
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like	0	Direct
50249,55681 50249 - Nucleic acid-binding proteins 55681 - Class II aaRS and biotin synthetases	0.004509	Inherited
55681,52954 55681 - Class II aaRS and biotin synthetases 52954 - Class II aaRS ABD-related	0.1408	Inherited
55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase	0.1408	Inherited
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain	0.5872	Inherited

(show details)

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases	0	Direct
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases	0	Direct
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0	Direct
55973,55973,55973 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase 55973 - S-adenosylmethionine synthetase	0.1408	Inherited
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain	0.5872	Inherited

Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term

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Worm Phenotype (WP): level of transgene expression variant

Superfamily

Family

Supra-domain (including individual superfamily)