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Xenopus ANatomical entity (XAN): trunk
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this XA term (SDXA level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| ClpS-like | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| NAP-like | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Cryptochrome/photolyase, N-terminal domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| MHC antigen-recognition domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Enolase C-terminal domain-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| ARM repeat | 0.00002299 | DIRECT |
| WD40 repeat-like | 0.0001983 | DIRECT |
| Ribonuclease H-like | 0.0004384 | DIRECT |
| NAD(P)-binding Rossmann-fold domains | 0.0008729 | DIRECT |
| Tudor/PWWP/MBT | 0.002992 | INHERITED FROM: gonad || testis |
| Actin-like ATPase domain | 0.003701 | INHERITED FROM: pancreas |
| RNA-binding domain, RBD | 0.006201 | INHERITED FROM: gonad || testis || intestine |
| P-loop containing nucleoside triphosphate hydrolases | 0.007823 | INHERITED FROM: gonad || testis |
| Translation proteins | 0.0615 | INHERITED FROM: primary oogonium || ovary || primary spermatogonium |
| PYP-like sensor domain (PAS domain) | 0.07097 | INHERITED FROM: epaxial muscle || trunk musculature |
| FYVE/PHD zinc finger | 0.1509 | INHERITED FROM: gonad || testis |
| Tropomyosin | 0.1616 | INHERITED FROM: left atrium || cardiac atrium || outflow tract || myocardium |
| PLP-dependent transferases | 0.2037 | INHERITED FROM: intestine |
| "Winged helix" DNA-binding domain | 0.2153 | INHERITED FROM: stomach |
| Leukotriene A4 hydrolase N-terminal domain | 0.2181 | INHERITED FROM: pancreas |
| Growth factor receptor domain | 0.2229 | INHERITED FROM: heart || coelom |
| ALDH-like | 0.2237 | INHERITED FROM: intestine |
| Orange domain-like | 0.2616 | INHERITED FROM: coelom |
| SMAD/FHA domain | 0.2708 | INHERITED FROM: endocardium |
| Clavaminate synthase-like | 0.2894 | INHERITED FROM: late distal tubule || late proximal tubule |
| Translation proteins SH3-like domain | 0.3113 | INHERITED FROM: pancreas |
| ARID-like | 0.3113 | INHERITED FROM: pronephric tubule |
| Translational machinery components | 0.4364 | INHERITED FROM: pancreas |
| Thioredoxin-like | 0.5315 | INHERITED FROM: early proximal tubule |
| HMG-box | 0.5578 | INHERITED FROM: endocardial tube || endocardium |
| Zn-binding ribosomal proteins | 0.5773 | INHERITED FROM: pancreas |
| Trypsin-like serine proteases | 0.6323 | INHERITED FROM: pancreas |
| EGF/Laminin | 0.6535 | INHERITED FROM: heart |
| SAM/Pointed domain | 0.7436 | INHERITED FROM: trunk vasculature |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.7683 | INHERITED FROM: proximal tubule branch |
| Snake toxin-like | 0.8262 | INHERITED FROM: trunk vasculature || heart || dorsal aorta |
| EF-hand | 0.9556 | INHERITED FROM: left atrium || cardiac ventricle || cardiac atrium || right atrium |
| Homeodomain-like | 1 | INHERITED FROM: early proximal tubule || proximal tubule branch || heart || proximal tubule || pronephric duct || late distal tubule || stomach || pronephric nephron || pronephric tubule || distal tubule || mesonephric duct || late proximal tubule || small intestine || large intestine || coelom || early distal tubule |
| lambda repressor-like DNA-binding domains | 1 | INHERITED FROM: proximal tubule || late distal tubule || pronephric tubule || distal tubule || early distal tubule |
| Troponin coil-coiled subunits | 1 | INHERITED FROM: heart |
| Cystine-knot cytokines | 1 | INHERITED FROM: trunk vasculature || heart || dorsal aorta |
| p53-like transcription factors | 1 | INHERITED FROM: heart || myocardium |
| HLH, helix-loop-helix DNA-binding domain | 1 | INHERITED FROM: heart || hypaxial muscle || stomach || trunk musculature || coelom |
| Frizzled cysteine-rich domain | 1 | INHERITED FROM: gall bladder || stomach || small intestine || coelom |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| ClpS-like | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| SCP-like | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| LysM domain | 0 | Direct |
| SAP domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Sialidases | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| KA1-like | 0 | Direct |
| GFP-like | 0 | Direct |
| MIT domain | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Tim10-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| L27 domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| NAP-like | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| DUSP-like | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| MIR domain | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| ACP-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
| DNA clamp | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| BAG domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Cryptochrome/photolyase, N-terminal domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Proteasome activator | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| FF domain | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| MHC antigen-recognition domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| TGS-like | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| WGR domain-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| SIS domain | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| PAZ domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| PapD-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| BSD domain-like | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| GYF domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Enolase C-terminal domain-like | 0 | Direct |
| UBC-like | 0 | Direct |
| Nop domain | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Notch domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Insulin-like | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| SRF-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| eIF1-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| ARM repeat | 0.00002299 | Direct |
| WD40 repeat-like | 0.0001983 | Direct |
| Ribonuclease H-like | 0.0004384 | Direct |
| NAD(P)-binding Rossmann-fold domains | 0.0008729 | Direct |
| Tudor/PWWP/MBT | 0.002992 | Inherited |
| Actin-like ATPase domain | 0.003701 | Inherited |
| RNA-binding domain, RBD | 0.006201 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.007823 | Inherited |
| Translation proteins | 0.0615 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.07097 | Inherited |
| FYVE/PHD zinc finger | 0.1509 | Inherited |
| Tropomyosin | 0.1616 | Inherited |
| PLP-dependent transferases | 0.2037 | Inherited |
| "Winged helix" DNA-binding domain | 0.2153 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.2181 | Inherited |
| Growth factor receptor domain | 0.2229 | Inherited |
| ALDH-like | 0.2237 | Inherited |
| Orange domain-like | 0.2616 | Inherited |
| SMAD/FHA domain | 0.2708 | Inherited |
| Clavaminate synthase-like | 0.2894 | Inherited |
| Translation proteins SH3-like domain | 0.3113 | Inherited |
| ARID-like | 0.3113 | Inherited |
| Translational machinery components | 0.4364 | Inherited |
| Thioredoxin-like | 0.5315 | Inherited |
| HMG-box | 0.5578 | Inherited |
| Zn-binding ribosomal proteins | 0.5773 | Inherited |
| Trypsin-like serine proteases | 0.6323 | Inherited |
| EGF/Laminin | 0.6535 | Inherited |
| SAM/Pointed domain | 0.7436 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.7683 | Inherited |
| Snake toxin-like | 0.8262 | Inherited |
| EF-hand | 0.9556 | Inherited |
| Homeodomain-like | 1 | Inherited |
| lambda repressor-like DNA-binding domains | 1 | Inherited |
| Troponin coil-coiled subunits | 1 | Inherited |
| Cystine-knot cytokines | 1 | Inherited |
| p53-like transcription factors | 1 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 1 | Inherited |
| Frizzled cysteine-rich domain | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this XA term (SDXA level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| Hedgehog (development protein), N-terminal signaling domain | 0 | DIRECT |
| Ferritin | 0 | DIRECT |
| GRAM domain | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| ELL N2 domain-like | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Elongation factors | 0 | DIRECT |
| APC10-like | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Complement components | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Fibronectin type II module | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| Mib/herc2 domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Cofactor-dependent phosphoglycerate mutase | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| MHC antigen-recognition domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| RWD domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| Thrombospondin C-terminal domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Cell cycle transcription factor e2f-dp | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Protein-L-isoaspartyl O-methyltransferase | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| GS domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| CAD domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| Glucose 6-phosphate dehydrogenase-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| CUE domain | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| gamma-adaptin C-terminal appendage domain-like | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| UDPGT-like | 0 | DIRECT |
| Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| TRASH domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| NIPSNAP | 0 | DIRECT |
| DNA ligase | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Pointed domain | 0 | DIRECT |
| Autophagin-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Fibronectin type I module | 0 | DIRECT |
| Netrin-like domain (NTR/C345C module) | 0 | DIRECT |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | DIRECT |
| Alpha-adaptin ear subdomain-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| SIAH, seven in absentia homolog | 0 | DIRECT |
| GABARAP-like | 0 | DIRECT |
| C1 set domains (antibody constant domain-like) | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| Sedlin (SEDL) | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| (Glycosyl)asparaginase | 0 | DIRECT |
| LON domain-like | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Neurotrophin | 0 | DIRECT |
| MSP-like | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Variant RING domain | 0 | DIRECT |
| U-box | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| Alanine racemase-like, N-terminal domain | 0 | DIRECT |
| Other IPT/TIG domains | 0 | DIRECT |
| RPR domain (SMART 00582 ) | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| GAT domain | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| ZZ domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Eukaryotic ODC-like | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| NAP-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| SEA domain | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Carboxylesterase/thioesterase 1 | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| A20-like zinc finger | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Domain G2 of nidogen-1 | 0 | DIRECT |
| Neutral endopeptidase (neprilysin) | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| MAPEG domain | 0 | DIRECT |
| ECR1 N-terminal domain-like | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| THAP domain | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Occludin/ELL domain | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Synatpobrevin N-terminal domain | 0 | DIRECT |
| P4 origin-binding domain-like | 0 | DIRECT |
| Retinol binding protein-like | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| UBX domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| Lectin leg-like | 0 | DIRECT |
| Chromo barrel domain | 0 | DIRECT |
| BSD domain | 0 | DIRECT |
| Malic enzyme N-domain | 0 | DIRECT |
| TRAPP components | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Cryptochrome/photolyase, N-terminal domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Steroid-binding domain | 0 | DIRECT |
| Ran-binding domain | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| Noncollagenous (NC1) domain of collagen IV | 0 | DIRECT |
| Transferrin | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| AraD-like aldolase/epimerase | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | DIRECT |
| B56-like | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| Tudor domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0.0001402 | DIRECT |
| WD40-repeat | 0.001007 | INHERITED FROM: gonad || testis || intestine |
| Canonical RBD | 0.001048 | INHERITED FROM: gonad || testis || intestine |
| PHD domain | 0.006412 | INHERITED FROM: gonad || testis |
| Extended AAA-ATPase domain | 0.024 | INHERITED FROM: gonad || testis |
| Tropomyosin | 0.06826 | INHERITED FROM: left atrium || cardiac atrium || outflow tract || myocardium |
| LIM domain | 0.09212 | INHERITED FROM: heart |
| GABA-aminotransferase-like | 0.1245 | INHERITED FROM: intestine |
| Nitrogenase iron protein-like | 0.1531 | INHERITED FROM: testis |
| ALDH-like | 0.1878 | INHERITED FROM: intestine |
| Leukotriene A4 hydrolase N-terminal domain | 0.2263 | INHERITED FROM: pancreas |
| Hairy Orange domain | 0.2263 | INHERITED FROM: coelom |
| Leukotriene A4 hydrolase catalytic domain | 0.2263 | INHERITED FROM: pancreas |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0.2353 | INHERITED FROM: epaxial muscle || pronephric nephron || pronephric tubule || trunk musculature |
| ARID domain | 0.2697 | INHERITED FROM: pronephric tubule |
| Class I aldolase | 0.3278 | INHERITED FROM: heart || pronephric kidney || coelom |
| 28-residue LRR | 0.34 | INHERITED FROM: epaxial muscle || trunk musculature |
| Growth factor receptor domain | 0.3406 | INHERITED FROM: heart || coelom |
| Eukaryotic proteases | 0.3601 | INHERITED FROM: pancreas |
| Glutathione peroxidase-like | 0.39 | INHERITED FROM: early proximal tubule || proximal tubule || pronephric nephron || pronephric tubule || distal tubule || early distal tubule |
| Erythroid transcription factor GATA-1 | 0.4643 | INHERITED FROM: heart || myocardium |
| Laminin G-like module | 0.4788 | INHERITED FROM: ovary |
| HMG-box | 0.4903 | INHERITED FROM: endocardial tube || endocardium |
| Extracellular domain of cell surface receptors | 0.5284 | INHERITED FROM: trunk vasculature || dorsal aorta |
| G proteins | 0.5288 | INHERITED FROM: primary oogonium || primary spermatogonium |
| Parvalbumin | 0.7997 | INHERITED FROM: trunk musculature |
| Calmodulin-like | 0.9232 | INHERITED FROM: left atrium || cardiac ventricle || cardiac atrium || right atrium |
| Homeodomain | 1 | INHERITED FROM: early proximal tubule || proximal tubule branch || heart || proximal tubule || pronephric duct || late distal tubule || stomach || pronephric nephron || pronephric tubule || distal tubule || late proximal tubule || small intestine || large intestine || coelom || early distal tubule |
| Frizzled cysteine-rich domain | 1 | INHERITED FROM: gall bladder || stomach || small intestine || coelom |
| T-box | 1 | INHERITED FROM: heart || myocardium |
| POU-specific domain | 1 | INHERITED FROM: proximal tubule || pronephric duct || late distal tubule || pronephric tubule || distal tubule || early distal tubule |
| Transforming growth factor (TGF)-beta | 1 | INHERITED FROM: trunk vasculature || heart || dorsal aorta || early distal tubule |
| HLH, helix-loop-helix DNA-binding domain | 1 | INHERITED FROM: heart || hypaxial muscle || stomach || trunk musculature || coelom |
| Forkhead DNA-binding domain | 1 | INHERITED FROM: stomach || pronephric nephrostome || myocardium |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| Thiolase-related | 0 | Direct |
| Hedgehog (development protein), N-terminal signaling domain | 0 | Direct |
| Ferritin | 0 | Direct |
| GRAM domain | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| ELL N2 domain-like | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| MIR domain | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| LeuD-like | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Elongation factors | 0 | Direct |
| APC10-like | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| DNase I-like | 0 | Direct |
| Complement components | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| eIF1-like | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Fibronectin type II module | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| ets domain | 0 | Direct |
| Mib/herc2 domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Cofactor-dependent phosphoglycerate mutase | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| MHC antigen-recognition domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | Direct |
| Insulin-like | 0 | Direct |
| MutT-like | 0 | Direct |
| PUA domain | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| RWD domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| HD domain | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| Thrombospondin C-terminal domain | 0 | Direct |
| SAP domain | 0 | Direct |
| Cell cycle transcription factor e2f-dp | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Protein-L-isoaspartyl O-methyltransferase | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| GS domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| CAD domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| Glucose 6-phosphate dehydrogenase-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| Crotonase-like | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| Fumble-like | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| CUE domain | 0 | Direct |
| NagB-like | 0 | Direct |
| DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| Proteasome activator | 0 | Direct |
| L27 domain | 0 | Direct |
| gamma-adaptin C-terminal appendage domain-like | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| UDPGT-like | 0 | Direct |
| Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| TRASH domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| NIPSNAP | 0 | Direct |
| DNA ligase | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Pointed domain | 0 | Direct |
| Autophagin-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Fibronectin type I module | 0 | Direct |
| Netrin-like domain (NTR/C345C module) | 0 | Direct |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | Direct |
| Alpha-adaptin ear subdomain-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| IF2B-like | 0 | Direct |
| SRF-like | 0 | Direct |
| VHS domain | 0 | Direct |
| Notch domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| SIAH, seven in absentia homolog | 0 | Direct |
| GABARAP-like | 0 | Direct |
| C1 set domains (antibody constant domain-like) | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| Sedlin (SEDL) | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| PDI-like | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| (Glycosyl)asparaginase | 0 | Direct |
| LON domain-like | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Neurotrophin | 0 | Direct |
| MSP-like | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Variant RING domain | 0 | Direct |
| U-box | 0 | Direct |
| MIT domain | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| Alanine racemase-like, N-terminal domain | 0 | Direct |
| Other IPT/TIG domains | 0 | Direct |
| RPR domain (SMART 00582 ) | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| GAT domain | 0 | Direct |
| UBC-related | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| SMAD domain | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| ZZ domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| WGR domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| CAT-like | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Eukaryotic ODC-like | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Type II chitinase | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| NAP-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| SEA domain | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Carboxylesterase/thioesterase 1 | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| PAH2 domain | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| PAZ domain | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| HCP-like | 0 | Direct |
| A20-like zinc finger | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Domain G2 of nidogen-1 | 0 | Direct |
| Neutral endopeptidase (neprilysin) | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| MAPEG domain | 0 | Direct |
| ECR1 N-terminal domain-like | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| THAP domain | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| BAG domain | 0 | Direct |
| Occludin/ELL domain | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Synatpobrevin N-terminal domain | 0 | Direct |
| P4 origin-binding domain-like | 0 | Direct |
| Retinol binding protein-like | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| UBX domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| AAT-like | 0 | Direct |
| Lectin leg-like | 0 | Direct |
| Chromo barrel domain | 0 | Direct |
| BSD domain | 0 | Direct |
| Malic enzyme N-domain | 0 | Direct |
| TRAPP components | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Cryptochrome/photolyase, N-terminal domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Steroid-binding domain | 0 | Direct |
| Ran-binding domain | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| Noncollagenous (NC1) domain of collagen IV | 0 | Direct |
| Transferrin | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Nop domain | 0 | Direct |
| LysM domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Cullin repeat | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| AraD-like aldolase/epimerase | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | Direct |
| B56-like | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Reductases | 0 | Direct |
| Tudor domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| FF domain | 0 | Direct |
| Tandem AAA-ATPase domain | 0.0001402 | Direct |
| WD40-repeat | 0.001007 | Inherited |
| Canonical RBD | 0.001048 | Inherited |
| PHD domain | 0.006412 | Inherited |
| Extended AAA-ATPase domain | 0.024 | Inherited |
| Tropomyosin | 0.06826 | Inherited |
| LIM domain | 0.09212 | Inherited |
| GABA-aminotransferase-like | 0.1245 | Inherited |
| Nitrogenase iron protein-like | 0.1531 | Inherited |
| ALDH-like | 0.1878 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.2263 | Inherited |
| Hairy Orange domain | 0.2263 | Inherited |
| Leukotriene A4 hydrolase catalytic domain | 0.2263 | Inherited |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0.2353 | Inherited |
| ARID domain | 0.2697 | Inherited |
| Class I aldolase | 0.3278 | Inherited |
| 28-residue LRR | 0.34 | Inherited |
| Growth factor receptor domain | 0.3406 | Inherited |
| Eukaryotic proteases | 0.3601 | Inherited |
| Glutathione peroxidase-like | 0.39 | Inherited |
| Erythroid transcription factor GATA-1 | 0.4643 | Inherited |
| Laminin G-like module | 0.4788 | Inherited |
| HMG-box | 0.4903 | Inherited |
| Extracellular domain of cell surface receptors | 0.5284 | Inherited |
| G proteins | 0.5288 | Inherited |
| Parvalbumin | 0.7997 | Inherited |
| Calmodulin-like | 0.9232 | Inherited |
| Homeodomain | 1 | Inherited |
| Frizzled cysteine-rich domain | 1 | Inherited |
| T-box | 1 | Inherited |
| POU-specific domain | 1 | Inherited |
| Transforming growth factor (TGF)-beta | 1 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 1 | Inherited |
| Forkhead DNA-binding domain | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this XA term (SPXA level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| UBC-like | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Enolase C-terminal domain-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Cryptochrome/photolyase, N-terminal domain | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| NAP-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| MHC antigen-recognition domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| ARM repeat | 0.00001668 | DIRECT |
| WD40 repeat-like | 0.0001474 | DIRECT |
| Ribonuclease H-like | 0.0003293 | DIRECT |
| NAD(P)-binding Rossmann-fold domains | 0.0006613 | DIRECT |
| Tudor/PWWP/MBT | 0.002304 | INHERITED FROM: testis || gonad |
| Actin-like ATPase domain | 0.002851 | INHERITED FROM: heart || pancreas |
| RNA-binding domain, RBD | 0.004823 | INHERITED FROM: testis || gonad || intestine |
| P-loop containing nucleoside triphosphate hydrolases | 0.006108 | INHERITED FROM: testis || gonad |
| Translation proteins | 0.05077 | INHERITED FROM: primary spermatogonium || ovary || primary oogonium |
| PYP-like sensor domain (PAS domain) | 0.05899 | INHERITED FROM: trunk musculature || epaxial muscle |
| FYVE/PHD zinc finger | 0.1312 | INHERITED FROM: testis || gonad |
| Tropomyosin | 0.1408 | INHERITED FROM: outflow tract || myocardium || left atrium || cardiac atrium |
| PLP-dependent transferases | 0.1797 | INHERITED FROM: intestine |
| "Winged helix" DNA-binding domain | 0.1908 | INHERITED FROM: stomach |
| Leukotriene A4 hydrolase N-terminal domain | 0.1935 | INHERITED FROM: pancreas |
| Growth factor receptor domain | 0.1982 | INHERITED FROM: heart || coelom |
| ALDH-like | 0.1989 | INHERITED FROM: intestine |
| Orange domain-like | 0.2345 | INHERITED FROM: heart || coelom |
| SMAD/FHA domain | 0.2435 | INHERITED FROM: endocardium || heart |
| Clavaminate synthase-like | 0.2611 | INHERITED FROM: late proximal tubule || early proximal tubule || late distal tubule |
| Translation proteins SH3-like domain | 0.2822 | INHERITED FROM: pancreas |
| ARID-like | 0.2822 | INHERITED FROM: pronephric tubule |
| Translational machinery components | 0.4031 | INHERITED FROM: pancreas |
| Thioredoxin-like | 0.4962 | INHERITED FROM: early proximal tubule |
| HMG-box | 0.5212 | INHERITED FROM: endocardium || endocardial tube |
| Zn-binding ribosomal proteins | 0.5412 | INHERITED FROM: pancreas |
| Trypsin-like serine proteases | 0.5965 | INHERITED FROM: pancreas |
| EGF/Laminin | 0.6176 | INHERITED FROM: heart |
| SAM/Pointed domain | 0.7091 | INHERITED FROM: trunk vasculature |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.7341 | INHERITED FROM: proximal tubule branch |
| Snake toxin-like | 0.7952 | INHERITED FROM: trunk vasculature || dorsal aorta || heart |
| EF-hand | 0.9277 | INHERITED FROM: right atrium || cardiac ventricle || left atrium || cardiac atrium |
| Cystine-knot cytokines | 1 | INHERITED FROM: trunk vasculature || dorsal aorta || heart |
| HLH, helix-loop-helix DNA-binding domain | 1 | INHERITED FROM: hypaxial muscle || trunk musculature || stomach || heart || coelom |
| Frizzled cysteine-rich domain | 1 | INHERITED FROM: gall bladder || stomach || small intestine || coelom |
| lambda repressor-like DNA-binding domains | 1 | INHERITED FROM: pronephric tubule || distal tubule || early distal tubule || proximal tubule || late distal tubule |
| Homeodomain-like | 1 | INHERITED FROM: pronephric tubule || distal tubule || pronephric nephron || large intestine || late proximal tubule || pronephric duct || proximal tubule branch || mesonephric duct || stomach || early distal tubule || early proximal tubule || heart || small intestine || coelom || proximal tubule || late distal tubule |
| Troponin coil-coiled subunits | 1 | INHERITED FROM: heart |
| Immunoglobulin | 1 | INHERITED FROM: spleen |
| p53-like transcription factors | 1 | INHERITED FROM: myocardium || heart |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| UBC-like | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| DNA clamp | 0 | Direct |
| NTF2-like | 0 | Direct |
| SCP-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Nop domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Thiolase-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| L27 domain | 0 | Direct |
| Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Sialidases | 0 | Direct |
| FF domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Enolase C-terminal domain-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| SAP domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| SIS domain | 0 | Direct |
| Cryptochrome/photolyase, N-terminal domain | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| LysM domain | 0 | Direct |
| GYF domain | 0 | Direct |
| MIT domain | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| eIF1-like | 0 | Direct |
| GFP-like | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| WGR domain-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| TGS-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| PapD-like | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| ClpS-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| BSD domain-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| DUSP-like | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| SRF-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| NAP-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| BAG domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| KA1-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Tim10-like | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| HRDC-like | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| ACP-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Insulin-like | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| Notch domain | 0 | Direct |
| MHC antigen-recognition domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| MIR domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| ARM repeat | 0.00001668 | Direct |
| WD40 repeat-like | 0.0001474 | Direct |
| Ribonuclease H-like | 0.0003293 | Direct |
| NAD(P)-binding Rossmann-fold domains | 0.0006613 | Direct |
| Tudor/PWWP/MBT | 0.002304 | Inherited |
| Actin-like ATPase domain | 0.002851 | Inherited |
| RNA-binding domain, RBD | 0.004823 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.006108 | Inherited |
| Translation proteins | 0.05077 | Inherited |
| PYP-like sensor domain (PAS domain) | 0.05899 | Inherited |
| FYVE/PHD zinc finger | 0.1312 | Inherited |
| Tropomyosin | 0.1408 | Inherited |
| PLP-dependent transferases | 0.1797 | Inherited |
| "Winged helix" DNA-binding domain | 0.1908 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.1935 | Inherited |
| Growth factor receptor domain | 0.1982 | Inherited |
| ALDH-like | 0.1989 | Inherited |
| Orange domain-like | 0.2345 | Inherited |
| SMAD/FHA domain | 0.2435 | Inherited |
| Clavaminate synthase-like | 0.2611 | Inherited |
| Translation proteins SH3-like domain | 0.2822 | Inherited |
| ARID-like | 0.2822 | Inherited |
| Translational machinery components | 0.4031 | Inherited |
| Thioredoxin-like | 0.4962 | Inherited |
| HMG-box | 0.5212 | Inherited |
| Zn-binding ribosomal proteins | 0.5412 | Inherited |
| Trypsin-like serine proteases | 0.5965 | Inherited |
| EGF/Laminin | 0.6176 | Inherited |
| SAM/Pointed domain | 0.7091 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.7341 | Inherited |
| Snake toxin-like | 0.7952 | Inherited |
| EF-hand | 0.9277 | Inherited |
| Cystine-knot cytokines | 1 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 1 | Inherited |
| Frizzled cysteine-rich domain | 1 | Inherited |
| lambda repressor-like DNA-binding domains | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
| Troponin coil-coiled subunits | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| p53-like transcription factors | 1 | Inherited |
(show details)
Supra-domains annotated to this XA term (SPXA level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | DIRECT |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | DIRECT |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | DIRECT |
57196,100895
57196 - EGF/Laminin
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | DIRECT |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | DIRECT |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | DIRECT |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | DIRECT |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52425,48173
52425 - Cryptochrome/photolyase, N-terminal domain
48173 - Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | DIRECT |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | DIRECT |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0 | DIRECT |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
50044,50156
50044 - SH3-domain
50156 - PDZ domain-like | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | DIRECT |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
54160,57850
54160 - Chromo domain-like
57850 - RING/U-box | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | DIRECT |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | DIRECT |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | DIRECT |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | DIRECT |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | DIRECT |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | DIRECT |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | DIRECT |
117281,50965
117281 - Kelch motif
50965 - Galactose oxidase, central domain | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0001999 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.006535 | INHERITED FROM: heart || pancreas |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.01724 | INHERITED FROM: testis || gonad |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.1422 | INHERITED FROM: heart |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0.1876 | INHERITED FROM: trunk musculature |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0.1935 | INHERITED FROM: pancreas |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.2345 | INHERITED FROM: heart || coelom |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.2438 | INHERITED FROM: heart |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.4697 | INHERITED FROM: viscus || intestine |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4949 | INHERITED FROM: dorsal aorta || heart |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0.7118 | INHERITED FROM: pancreas |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.9425 | INHERITED FROM: ovary |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 1 | INHERITED FROM: pronephric tubule |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | Direct |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | Direct |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | Direct |
57196,100895
57196 - EGF/Laminin
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | Direct |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | Direct |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | Direct |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | Direct |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | Direct |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | Direct |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52425,48173
52425 - Cryptochrome/photolyase, N-terminal domain
48173 - Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | Direct |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | Direct |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0 | Direct |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
50044,50156
50044 - SH3-domain
50156 - PDZ domain-like | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | Direct |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | Direct |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
54160,57850
54160 - Chromo domain-like
57850 - RING/U-box | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | Direct |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | Direct |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | Direct |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | Direct |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | Direct |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | Direct |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | Direct |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | Direct |
117281,50965
117281 - Kelch motif
50965 - Galactose oxidase, central domain | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.0001999 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.006535 | Inherited |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.01724 | Inherited |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.1422 | Inherited |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0.1876 | Inherited |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0.1935 | Inherited |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.2345 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.2438 | Inherited |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.4697 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4949 | Inherited |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0.7118 | Inherited |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.9425 | Inherited |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 1 | Inherited |
(show details)
Supra-domains annotated to this XA term (SPXA level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49785,49785,49899
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
54160,57850,57845
54160 - Chromo domain-like
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | DIRECT |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
57196,49899,57196
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54511,57184,57184
54511 - GFP-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.1702 | INHERITED FROM: heart |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.2157 | INHERITED FROM: ovary |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.3221 | INHERITED FROM: coelom |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.3221 | INHERITED FROM: heart |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.4177 | INHERITED FROM: heart |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0.6593 | INHERITED FROM: trunk somite || coelom |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
49785,49785,49899
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
54160,57850,57845
54160 - Chromo domain-like
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | Direct |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
57196,49899,57196
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54511,57184,57184
54511 - GFP-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.1702 | Inherited |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.2157 | Inherited |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0.3221 | Inherited |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.3221 | Inherited |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.4177 | Inherited |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0.6593 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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