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Xenopus ANatomical entity (XAN): anatomical region
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this XA term (Not in SDXA)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| ClpS-like | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| gamma-Crystallin-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Dimeric alpha+beta barrel | 0 | DIRECT |
| TRAF domain-like | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| NAP-like | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| Crisp domain-like | 0 | DIRECT |
| Cyclin-like | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| FnI-like domain | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
| SRCR-like | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| Cryptochrome/photolyase, N-terminal domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| MHC antigen-recognition domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Globin-like | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Actin-crosslinking proteins | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Hook domain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Enolase C-terminal domain-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| RNA-binding domain, RBD | 0.003383 | INHERITED FROM: intestine || eye || vegetal pole || pharyngeal region || gonad || pharyngeal arch || hindbrain || testis |
| ARM repeat | 0.003449 | INHERITED FROM: trunk region || trunk || gonad || testis |
| P-loop containing nucleoside triphosphate hydrolases | 0.01459 | INHERITED FROM: gonad || testis |
| Protein kinase-like (PK-like) | 0.03161 | INHERITED FROM: animal hemisphere || head mesoderm |
| Growth factor receptor domain | 0.05338 | INHERITED FROM: heart || tail tip || coelom |
| WD40 repeat-like | 0.1079 | INHERITED FROM: trunk region || intestine || trunk || gonad || testis |
| Ubiquitin-like | 0.1093 | INHERITED FROM: brain || head region || head |
| Actin-like ATPase domain | 0.1187 | INHERITED FROM: jaw muscle || pancreas || cranial muscle || head somite |
| HMG-box | 0.1187 | INHERITED FROM: midbrain-hindbrain boundary || forebrain || optic field || endocardial tube || endocardium || pharyngeal region || pharyngeal arch || hindbrain || splanchnocranium |
| "Winged helix" DNA-binding domain | 0.128 | INHERITED FROM: animal hemisphere || tail fin || eye || optic field || intersomitic region || pharyngeal region || tail tip || head mesoderm || periocular region || stomach || pharyngeal arch || visceral pouch |
| Ribonuclease H-like | 0.1416 | INHERITED FROM: trunk region || trunk || gonad || testis |
| PLP-dependent transferases | 0.1895 | INHERITED FROM: intestine |
| Plexin repeat | 0.2253 | INHERITED FROM: periocular region || branchial arch |
| NAD(P)-binding Rossmann-fold domains | 0.3128 | INHERITED FROM: trunk region || intestine || trunk |
| GST C-terminal domain-like | 0.3318 | INHERITED FROM: tail region |
| F-box domain | 0.3534 | INHERITED FROM: animal hemisphere |
| Tudor/PWWP/MBT | 0.369 | INHERITED FROM: gonad || testis |
| Tubulin nucleotide-binding domain-like | 0.4128 | INHERITED FROM: intersomitic neuron || glossopharyngeal nerve || trigeminal nerve || facial nerve || vagus nerve || vegetal hemisphere |
| Thioredoxin-like | 0.4299 | INHERITED FROM: tail region || early proximal tubule || tail |
| Tubulin C-terminal domain-like | 0.4351 | INHERITED FROM: intersomitic neuron || glossopharyngeal nerve || trigeminal nerve || facial nerve || vagus nerve || vegetal hemisphere |
| Voltage-gated potassium channels | 0.4721 | INHERITED FROM: retinal neural layer || optic nerve || optic disc || cephalic nerve || retinal ganglion cell layer || retinal inner plexiform layer |
| ALDH-like | 0.4863 | INHERITED FROM: intestine |
| TIMP-like | 0.512 | INHERITED FROM: optic field |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.5764 | INHERITED FROM: medial septum || amygdala || septum || ventrolateral thalamic nucleus || forebrain || lateral septum || intersomitic region || hypothalamus || zona limitans intrathalamica || pretectum || diencephalon || subpallium || anterior hypothalamus || thalamus || optic tectum || proximal tubule branch || basal forebrain || ventral septum || ventral pallium || prosomere || midbrain || basal ganglion || hindbrain || striatum || preoptic area |
| PH domain-like | 0.5859 | INHERITED FROM: brain |
| SAM/Pointed domain | 0.6085 | INHERITED FROM: trunk vasculature |
| Tropomyosin | 0.6527 | INHERITED FROM: myocardium || left atrium || outflow tract || cardiac atrium |
| Translation proteins SH3-like domain | 0.6657 | INHERITED FROM: pancreas |
| CCCH zinc finger | 0.6746 | INHERITED FROM: animal pole |
| GroEL apical domain-like | 0.7001 | INHERITED FROM: tail region |
| Leukotriene A4 hydrolase N-terminal domain | 0.7001 | INHERITED FROM: pancreas |
| p53-like transcription factors | 0.7149 | INHERITED FROM: heart || branchial arch skeleton || myocardium || lower jaw || pharyngeal region || chondrocranium || ceratohyal || Meckel's cartilage || pharyngeal arch || facial nerve |
| Intermediate filament protein, coiled coil region | 0.7149 | INHERITED FROM: retinal inner nuclear layer || optic nerve || tail region || midbrain tegmentum || cephalic nerve || ventricular zone || tail || retinal ganglion cell || retinal ganglion cell layer || retinal inner plexiform layer || medulla oblongata |
| Orange domain-like | 0.7381 | INHERITED FROM: eye || pharyngeal region || chordoneural hinge || tail tip || coelom || midbrain |
| GroEL equatorial domain-like | 0.7381 | INHERITED FROM: tail region || tail |
| Fibronectin type III | 0.7617 | INHERITED FROM: retinal neural layer || retinal inner nuclear layer || retinal ganglion cell layer |
| HLH, helix-loop-helix DNA-binding domain | 0.7659 | INHERITED FROM: head vasculature || tail bud || heart || cranium || retinal inner nuclear layer || tail fin || eye || forebrain || retinal outer nuclear layer || optic field || hypaxial muscle || retinal stem cell region || intersomitic region || hyoid head muscle || trunk musculature || pharyngeal region || chordoneural hinge || tail tip || musculature of face || ventricular zone || m. interhyoideus || cranial ganglion || periocular region || coelom || retinal ganglion cell layer || midbrain || stomach || pharyngeal arch || olfactory region || hindbrain || cranial muscle |
| SMAD/FHA domain | 0.7994 | INHERITED FROM: endocardium |
| EF-hand | 0.8044 | INHERITED FROM: cardiac ventricle || left atrium || right atrium || cardiac atrium |
| Troponin coil-coiled subunits | 0.8121 | INHERITED FROM: heart |
| EGF/Laminin | 0.8191 | INHERITED FROM: heart |
| Myosin rod fragments | 0.8357 | INHERITED FROM: musculature of face |
| Translational machinery components | 0.853 | INHERITED FROM: pancreas |
| FYVE/PHD zinc finger | 0.8601 | INHERITED FROM: gonad || testis |
| SOCS box-like | 0.9861 | INHERITED FROM: tail |
| Trypsin-like serine proteases | 1 | INHERITED FROM: pancreas |
| Homeodomain-like | 1 | INHERITED FROM: dorsal thalamus || tail bud || medial septum || heart || proximal tubule || midbrain-hindbrain boundary || olfactory bulb || cranium || retinal inner nuclear layer || tail fin || prethalamus || lateral ganglionic eminence || amygdala || distal tubule || septum || neurocranium || eye || pronephric tubule || mouth || forebrain || optic field || lateral septum || hypothalamus || telencephalon || medial ganglionic eminence || early proximal tubule || zona limitans intrathalamica || posterior wall of neurenteric canal || lower jaw || large intestine || early distal tubule || pharyngeal region || chordoneural hinge || pretectum || late proximal tubule || diencephalon || tail tip || optic stalk || mesonephric duct || subpallium || anterior hypothalamus || periotic region || head mesenchyme || infundibulum || pallidum || thalamus || lateral pallium || cephalic nerve || ventricular zone || late distal tubule || proximal tubule branch || neurenteric canal || pharyngeal endoderm || basal forebrain || coelom || ventral septum || small intestine || ventral pallium || retinal ganglion cell layer || prosomere || pronephric nephron || midbrain || stomach || pharyngeal arch || olfactory region || pronephric duct || basal ganglion || rhombomere || hindbrain || retinal pigmented epithelium || posterior hypothalamus || optic tract || pharyngeal pouch || preoptic area || pallium || visceral pouch |
| TSP-1 type 1 repeat | 1 | INHERITED FROM: rectal diverticulum |
| lambda repressor-like DNA-binding domains | 1 | INHERITED FROM: proximal tubule || distal tubule || pronephric tubule || early distal tubule || late distal tubule |
| POZ domain | 1 | INHERITED FROM: optic disc |
| Cystine-knot cytokines | 1 | INHERITED FROM: animal hemisphere || heart || branchial arch 3 || head mesenchyme || branchial arch 2 || head mesoderm || periocular region || trunk vasculature || vegetal hemisphere || dorsal aorta |
| Metalloproteases ("zincins"), catalytic domain | 1 | INHERITED FROM: rectal diverticulum |
| SH2 domain | 1 | INHERITED FROM: animal pole |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: medial pallium || amygdala || granule cell layer of the olfactory bulb || septum || hypothalamus || diencephalon || anterior hypothalamus || basal forebrain || basal ganglion || striatum || preoptic area || pallium |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| ClpS-like | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Annexin | 0 | Direct |
| SCP-like | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| LysM domain | 0 | Direct |
| SAP domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| GroES-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| gamma-Crystallin-like | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Sialidases | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| LigT-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Synuclein | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| KA1-like | 0 | Direct |
| GFP-like | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Dimeric alpha+beta barrel | 0 | Direct |
| TRAF domain-like | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| PRTase-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| MIT domain | 0 | Direct |
| Stathmin | 0 | Direct |
| HCP-like | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Tim10-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| Pentein | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| L27 domain | 0 | Direct |
| BEACH domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| NAP-like | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Sema domain | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| L30e-like | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| Crisp domain-like | 0 | Direct |
| Cyclin-like | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| DNase I-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| ARID-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| FnI-like domain | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| DUSP-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| Ras GEF | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| MIR domain | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| ACP-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
| SRCR-like | 0 | Direct |
| Mss4-like | 0 | Direct |
| YWTD domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| DNA clamp | 0 | Direct |
| Nudix | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| BAG domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| FAS1 domain | 0 | Direct |
| Cryptochrome/photolyase, N-terminal domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| PR-1-like | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| FF domain | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| ACT-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| MHC antigen-recognition domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| TGS-like | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| WGR domain-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Globin-like | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Actin-crosslinking proteins | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Connexin43 | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| LCCL domain | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| HRDC-like | 0 | Direct |
| SIS domain | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Cupredoxins | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| Polo-box domain | 0 | Direct |
| PAZ domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| PapD-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| Plakin repeat | 0 | Direct |
| BSD domain-like | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| GYF domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Hook domain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Enolase C-terminal domain-like | 0 | Direct |
| UBC-like | 0 | Direct |
| DLC | 0 | Direct |
| Nop domain | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Notch domain | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Insulin-like | 0 | Direct |
| R3H domain | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| SRF-like | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Cytokine | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| LEM domain | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| eIF1-like | 0 | Direct |
| Translation proteins | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| PEBP-like | 0 | Direct |
| RNA-binding domain, RBD | 0.003383 | Inherited |
| ARM repeat | 0.003449 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.01459 | Inherited |
| Protein kinase-like (PK-like) | 0.03161 | Inherited |
| Growth factor receptor domain | 0.05338 | Inherited |
| WD40 repeat-like | 0.1079 | Inherited |
| Ubiquitin-like | 0.1093 | Inherited |
| Actin-like ATPase domain | 0.1187 | Inherited |
| HMG-box | 0.1187 | Inherited |
| "Winged helix" DNA-binding domain | 0.128 | Inherited |
| Ribonuclease H-like | 0.1416 | Inherited |
| PLP-dependent transferases | 0.1895 | Inherited |
| Plexin repeat | 0.2253 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.3128 | Inherited |
| GST C-terminal domain-like | 0.3318 | Inherited |
| F-box domain | 0.3534 | Inherited |
| Tudor/PWWP/MBT | 0.369 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.4128 | Inherited |
| Thioredoxin-like | 0.4299 | Inherited |
| Tubulin C-terminal domain-like | 0.4351 | Inherited |
| Voltage-gated potassium channels | 0.4721 | Inherited |
| ALDH-like | 0.4863 | Inherited |
| TIMP-like | 0.512 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.5764 | Inherited |
| PH domain-like | 0.5859 | Inherited |
| SAM/Pointed domain | 0.6085 | Inherited |
| Tropomyosin | 0.6527 | Inherited |
| Translation proteins SH3-like domain | 0.6657 | Inherited |
| CCCH zinc finger | 0.6746 | Inherited |
| GroEL apical domain-like | 0.7001 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.7001 | Inherited |
| p53-like transcription factors | 0.7149 | Inherited |
| Intermediate filament protein, coiled coil region | 0.7149 | Inherited |
| Orange domain-like | 0.7381 | Inherited |
| GroEL equatorial domain-like | 0.7381 | Inherited |
| Fibronectin type III | 0.7617 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.7659 | Inherited |
| SMAD/FHA domain | 0.7994 | Inherited |
| EF-hand | 0.8044 | Inherited |
| Troponin coil-coiled subunits | 0.8121 | Inherited |
| EGF/Laminin | 0.8191 | Inherited |
| Myosin rod fragments | 0.8357 | Inherited |
| Translational machinery components | 0.853 | Inherited |
| FYVE/PHD zinc finger | 0.8601 | Inherited |
| SOCS box-like | 0.9861 | Inherited |
| Trypsin-like serine proteases | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
| TSP-1 type 1 repeat | 1 | Inherited |
| lambda repressor-like DNA-binding domains | 1 | Inherited |
| POZ domain | 1 | Inherited |
| Cystine-knot cytokines | 1 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
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Family(show details)
Family domains annotated to this XA term (Not in SDXA)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| AlkB-like | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Hedgehog (development protein), N-terminal signaling domain | 0 | DIRECT |
| Ferritin | 0 | DIRECT |
| GRAM domain | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| ELL N2 domain-like | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| PreBEACH PH-like domain | 0 | DIRECT |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| ENTH domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| VWC domain | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Elongation factors | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| APC10-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| Hook domain | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Complement components | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Fibronectin type II module | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Mib/herc2 domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Pyridoxal-dependent decarboxylase | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Cofactor-dependent phosphoglycerate mutase | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| MHC antigen-recognition domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| Cold shock DNA-binding domain-like | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| RWD domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| Cytochrome b5 | 0 | DIRECT |
| Thrombospondin C-terminal domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| IMD domain | 0 | DIRECT |
| Cell cycle transcription factor e2f-dp | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Protein-L-isoaspartyl O-methyltransferase | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| GS domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| CAD domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| Glucose 6-phosphate dehydrogenase-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| Methyl-CpG-binding domain, MBD | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| RUNT domain | 0 | DIRECT |
| CUE domain | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| gamma-adaptin C-terminal appendage domain-like | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Globins | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| UDPGT-like | 0 | DIRECT |
| Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| T-box | 0 | DIRECT |
| Gonadodropin/Follitropin | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| TRASH domain | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| NIPSNAP | 0 | DIRECT |
| Cyclophilin (peptidylprolyl isomerase) | 0 | DIRECT |
| DNA ligase | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| Pointed domain | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Phenylalanine metabolism regulatory domain | 0 | DIRECT |
| MPP-like | 0 | DIRECT |
| Autophagin-like | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Fibronectin type I module | 0 | DIRECT |
| Netrin-like domain (NTR/C345C module) | 0 | DIRECT |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| Alpha-adaptin ear subdomain-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| SIAH, seven in absentia homolog | 0 | DIRECT |
| GABARAP-like | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| C1 set domains (antibody constant domain-like) | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| Fucose binding lectin | 0 | DIRECT |
| Sedlin (SEDL) | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Prohormone convertase 1 pro-domain | 0 | DIRECT |
| Pseudouridine synthase II TruB | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| (Glycosyl)asparaginase | 0 | DIRECT |
| LON domain-like | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Extradiol dioxygenases | 0 | DIRECT |
| ATP-dependent DNA ligase catalytic domain | 0 | DIRECT |
| Anion transport protein, cytoplasmic domain | 0 | DIRECT |
| Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Neurotrophin | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| MSP-like | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Variant RING domain | 0 | DIRECT |
| U-box | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| Plakophilin 1 helical region | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| Alanine racemase-like, N-terminal domain | 0 | DIRECT |
| Other IPT/TIG domains | 0 | DIRECT |
| RPR domain (SMART 00582 ) | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Ephrin receptor ligand binding domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| GAT domain | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | DIRECT |
| MATH domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| Arrestin/Vps26-like | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| ZZ domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| DIX domain | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| Noggin | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Eukaryotic ODC-like | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| NAP-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | DIRECT |
| Nitrogenase iron protein-like | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| SEA domain | 0 | DIRECT |
| Phosducin | 0 | DIRECT |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| Carboxylesterase/thioesterase 1 | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| SPRY domain | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| A20-like zinc finger | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Domain G2 of nidogen-1 | 0 | DIRECT |
| Carboxylesterase | 0 | DIRECT |
| Neutral endopeptidase (neprilysin) | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| Putative glucosidase YicI, domain 3 | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| MAPEG domain | 0 | DIRECT |
| ECR1 N-terminal domain-like | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| THAP domain | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Occludin/ELL domain | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Synatpobrevin N-terminal domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| P4 origin-binding domain-like | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| Retinol binding protein-like | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| UBX domain | 0 | DIRECT |
| L domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Crystallins/Ca-binding development proteins | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Ribosomal protein L3 | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| Lectin leg-like | 0 | DIRECT |
| Chromo barrel domain | 0 | DIRECT |
| BSD domain | 0 | DIRECT |
| Malic enzyme N-domain | 0 | DIRECT |
| TRAPP components | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Cryptochrome/photolyase, N-terminal domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Crisp domain | 0 | DIRECT |
| Steroid-binding domain | 0 | DIRECT |
| Ran-binding domain | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| DJ-1/PfpI | 0 | DIRECT |
| Noncollagenous (NC1) domain of collagen IV | 0 | DIRECT |
| Transferrin | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Fibroblast growth factors (FGF) | 0 | DIRECT |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Ephrin ectodomain | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Prokaryotic proteases | 0 | DIRECT |
| Calnexin/calreticulin | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| Transcriptional factor tubby, C-terminal domain | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| RUN domain | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| AraD-like aldolase/epimerase | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| GDI-like N domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | DIRECT |
| B56-like | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Aldo-keto reductases (NADP) | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| Tudor domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Pseudouridine synthase RsuA/RluD | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Canonical RBD | 0.004573 | INHERITED FROM: intestine || eye || tail region || vegetal pole || pharyngeal region || tail || gonad || pharyngeal arch || hindbrain || testis |
| Tandem AAA-ATPase domain | 0.01276 | INHERITED FROM: trunk region || forebrain || trunk || gonad || midbrain || hindbrain || testis |
| Protein kinases, catalytic subunit | 0.02174 | INHERITED FROM: animal hemisphere || head mesoderm |
| Growth factor receptor domain | 0.06928 | INHERITED FROM: animal hemisphere || heart || coelom |
| HMG-box | 0.1018 | INHERITED FROM: midbrain-hindbrain boundary || forebrain || optic field || endocardial tube || endocardium || pharyngeal region || pharyngeal arch || hindbrain || splanchnocranium |
| Extended AAA-ATPase domain | 0.1153 | INHERITED FROM: gonad || testis |
| Motor proteins | 0.1376 | INHERITED FROM: musculature of face |
| Second domain of FERM | 0.1894 | INHERITED FROM: trigeminal nerve |
| Plexin repeat | 0.2014 | INHERITED FROM: periocular region || branchial arch |
| LIM domain | 0.2143 | INHERITED FROM: heart || amygdala || septum || ventrolateral thalamic nucleus || pretectum || central nucleus of the thalamus || thalamus || basal forebrain || bed nucleus of the stria terminalis || medial amygdala || ventral septum || prosomere || prosomere 4 || anterior thalamic nucleus |
| Laminin G-like module | 0.2277 | INHERITED FROM: ovary |
| PHD domain | 0.2353 | INHERITED FROM: gonad || testis |
| G proteins | 0.2424 | INHERITED FROM: primary spermatogonium || primary oogonium |
| WD40-repeat | 0.243 | INHERITED FROM: intestine || gonad || testis |
| F-box domain | 0.324 | INHERITED FROM: animal hemisphere |
| Forkhead DNA-binding domain | 0.3528 | INHERITED FROM: animal hemisphere || cranium || tail fin || myocardium || eye || optic field || pharyngeal region || chordoneural hinge || tail tip || head mesoderm || periocular region || pronephric nephrostome || stomach || pharyngeal arch || olfactory region || cloaca || visceral pouch |
| Tubulin, GTPase domain | 0.4028 | INHERITED FROM: intersomitic neuron || glossopharyngeal nerve || trigeminal nerve || facial nerve || vagus nerve || vegetal hemisphere |
| Tubulin, C-terminal domain | 0.4028 | INHERITED FROM: intersomitic neuron || glossopharyngeal nerve || trigeminal nerve || facial nerve || vagus nerve || vegetal hemisphere |
| Myosin rod fragments | 0.4518 | INHERITED FROM: musculature of face |
| ALDH-like | 0.4518 | INHERITED FROM: intestine |
| Proteasome subunits | 0.4785 | INHERITED FROM: tail region || tail |
| Glutathione S-transferase (GST), C-terminal domain | 0.5045 | INHERITED FROM: tail region |
| I set domains | 0.5051 | INHERITED FROM: retinal inner nuclear layer || pharyngeal mesenchyme || retinal ganglion cell layer |
| Glutathione S-transferase (GST), N-terminal domain | 0.5335 | INHERITED FROM: tail region |
| 28-residue LRR | 0.5627 | INHERITED FROM: epaxial muscle || trunk musculature |
| Voltage-gated potassium channels | 0.5674 | INHERITED FROM: optic nerve || optic disc || retinal inner plexiform layer |
| GABA-aminotransferase-like | 0.5952 | INHERITED FROM: intestine |
| Glutathione peroxidase-like | 0.5952 | INHERITED FROM: proximal tubule || cranium || distal tubule || pronephric tubule || tail region || intersomitic region || early proximal tubule || early distal tubule || tail || pronephric nephron || splanchnocranium |
| CCCH zinc finger | 0.6373 | INHERITED FROM: animal pole |
| Intermediate filament protein, coiled coil region | 0.6777 | INHERITED FROM: retinal inner nuclear layer || optic nerve || tail region || midbrain tegmentum || nucleus reticularis inferior || cephalic nerve || ventricular zone || tail || retinal ganglion cell || retinal ganglion cell layer || vestibulocochlear nerve || retinal inner plexiform layer || medulla oblongata |
| Tropomyosin | 0.6848 | INHERITED FROM: myocardium || left atrium || outflow tract || cardiac atrium |
| Leukotriene A4 hydrolase N-terminal domain | 0.6998 | INHERITED FROM: pancreas |
| Hairy Orange domain | 0.6998 | INHERITED FROM: eye || pharyngeal region || chordoneural hinge || tail tip || coelom || midbrain |
| Leukotriene A4 hydrolase catalytic domain | 0.6998 | INHERITED FROM: pancreas |
| HLH, helix-loop-helix DNA-binding domain | 0.7297 | INHERITED FROM: head vasculature || tail bud || heart || cranium || retinal inner nuclear layer || tail fin || eye || forebrain || retinal outer nuclear layer || optic field || hypaxial muscle || retinal stem cell region || intersomitic region || hyoid head muscle || trunk musculature || pharyngeal region || chordoneural hinge || tail tip || musculature of face || ventricular zone || m. interhyoideus || cranial ganglion || periocular region || coelom || retinal ganglion cell layer || midbrain || stomach || pharyngeal arch || olfactory region || hindbrain || cranial muscle |
| Fibronectin type III | 0.7358 | INHERITED FROM: retinal neural layer || retinal ganglion cell layer |
| Class I aldolase | 0.7795 | INHERITED FROM: heart || tail region || tail || coelom || pronephric kidney |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.7795 | INHERITED FROM: tail region || tail |
| Calmodulin-like | 0.7818 | INHERITED FROM: cardiac ventricle || left atrium || right atrium || cardiac atrium |
| Parvalbumin | 0.8216 | INHERITED FROM: trunk musculature || cranial muscle |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0.8621 | INHERITED FROM: retinal inner nuclear layer || retinal ganglion cell layer |
| POU-specific domain | 0.9236 | INHERITED FROM: proximal tubule || distal tubule || pronephric tubule || early distal tubule || late distal tubule || retinal ganglion cell layer || pronephric duct |
| SOCS box-like | 0.9599 | INHERITED FROM: tail |
| Eukaryotic proteases | 0.9978 | INHERITED FROM: pancreas |
| TSP-1 type 1 repeat | 0.999 | INHERITED FROM: rectal diverticulum |
| SH2 domain | 1 | INHERITED FROM: animal pole |
| Homeodomain | 1 | INHERITED FROM: dorsal thalamus || tail bud || medial septum || heart || proximal tubule || midbrain-hindbrain boundary || olfactory bulb || cranium || retinal inner nuclear layer || tail fin || prethalamus || lateral ganglionic eminence || amygdala || distal tubule || septum || neurocranium || eye || pronephric tubule || mouth || forebrain || optic field || lateral septum || intersomitic region || hypothalamus || telencephalon || medial ganglionic eminence || early proximal tubule || zona limitans intrathalamica || posterior wall of neurenteric canal || lower jaw || large intestine || early distal tubule || pharyngeal region || chordoneural hinge || pretectum || late proximal tubule || diencephalon || tail tip || optic stalk || subpallium || anterior hypothalamus || periotic region || head mesenchyme || infundibulum || pallidum || thalamus || lateral pallium || mandibular arch || cephalic nerve || ventricular zone || late distal tubule || proximal tubule branch || neurenteric canal || basal forebrain || bed nucleus of the stria terminalis || coelom || ventral septum || small intestine || ventral pallium || retinal ganglion cell layer || prosomere || pronephric nephron || midbrain || stomach || pharyngeal arch || olfactory region || pronephric duct || basal ganglion || rhombomere || hindbrain || posterior hypothalamus || striatum || preoptic area || pineal gland || pallium || visceral pouch |
| Transforming growth factor (TGF)-beta | 1 | INHERITED FROM: animal hemisphere || heart || branchial arch 3 || branchial arch 4 || early distal tubule || head mesenchyme || branchial arch 2 || branchial arch 1 || head mesoderm || periocular region || trunk vasculature || vegetal hemisphere || dorsal aorta |
| Rhodopsin-like | 1 | INHERITED FROM: medial pallium || amygdala || granule cell layer of the olfactory bulb || septum || hypothalamus || diencephalon || anterior hypothalamus || basal forebrain || basal ganglion || eye photoreceptor cell || striatum || preoptic area || pallium |
| Classic zinc finger, C2H2 | 1 | INHERITED FROM: midbrain || hindbrain |
| Tetramerization domain of potassium channels | 1 | INHERITED FROM: optic nerve || optic disc || retinal outer plexiform layer || retinal ganglion cell layer || retinal inner plexiform layer |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| AlkB-like | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| Stathmin | 0 | Direct |
| Thiolase-related | 0 | Direct |
| YWTD domain | 0 | Direct |
| Hedgehog (development protein), N-terminal signaling domain | 0 | Direct |
| Ferritin | 0 | Direct |
| GRAM domain | 0 | Direct |
| Hexokinase | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| ELL N2 domain-like | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| PreBEACH PH-like domain | 0 | Direct |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| MIR domain | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| ARID domain | 0 | Direct |
| ENTH domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| VWC domain | 0 | Direct |
| LeuD-like | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Elongation factors | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| APC10-like | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| Hook domain | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| DNase I-like | 0 | Direct |
| Complement components | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| eIF1-like | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Formyltransferase | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Fibronectin type II module | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| ets domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Mib/herc2 domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Pyridoxal-dependent decarboxylase | 0 | Direct |
| Adenain-like | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Cofactor-dependent phosphoglycerate mutase | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| MHC antigen-recognition domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | Direct |
| Insulin-like | 0 | Direct |
| MutT-like | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| FAS1 domain | 0 | Direct |
| PUA domain | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| LCCL domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| Cold shock DNA-binding domain-like | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| RWD domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| HD domain | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| Cytochrome b5 | 0 | Direct |
| Thrombospondin C-terminal domain | 0 | Direct |
| SAP domain | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| IMD domain | 0 | Direct |
| Cell cycle transcription factor e2f-dp | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Protein-L-isoaspartyl O-methyltransferase | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| GS domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| CAD domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| Glucose 6-phosphate dehydrogenase-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Crotonase-like | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| Fumble-like | 0 | Direct |
| Methyl-CpG-binding domain, MBD | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| RUNT domain | 0 | Direct |
| CUE domain | 0 | Direct |
| NagB-like | 0 | Direct |
| DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Prefoldin | 0 | Direct |
| L27 domain | 0 | Direct |
| gamma-adaptin C-terminal appendage domain-like | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Globins | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| UDPGT-like | 0 | Direct |
| Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| T-box | 0 | Direct |
| Gonadodropin/Follitropin | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| TRASH domain | 0 | Direct |
| Plakin repeat | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| NIPSNAP | 0 | Direct |
| Cyclophilin (peptidylprolyl isomerase) | 0 | Direct |
| DNA ligase | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| Paired domain | 0 | Direct |
| FCH domain | 0 | Direct |
| Pointed domain | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Phenylalanine metabolism regulatory domain | 0 | Direct |
| MPP-like | 0 | Direct |
| Autophagin-like | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Fibronectin type I module | 0 | Direct |
| Netrin-like domain (NTR/C345C module) | 0 | Direct |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| Alpha-adaptin ear subdomain-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| CCHHC domain | 0 | Direct |
| IF2B-like | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| SRF-like | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| VHS domain | 0 | Direct |
| Cyclin | 0 | Direct |
| Notch domain | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| SIAH, seven in absentia homolog | 0 | Direct |
| GABARAP-like | 0 | Direct |
| R3H domain | 0 | Direct |
| Sema domain | 0 | Direct |
| C1 set domains (antibody constant domain-like) | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| Fucose binding lectin | 0 | Direct |
| Sedlin (SEDL) | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Prohormone convertase 1 pro-domain | 0 | Direct |
| Pseudouridine synthase II TruB | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| PDI-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
| Annexin | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| (Glycosyl)asparaginase | 0 | Direct |
| LON domain-like | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Extradiol dioxygenases | 0 | Direct |
| ATP-dependent DNA ligase catalytic domain | 0 | Direct |
| Anion transport protein, cytoplasmic domain | 0 | Direct |
| Phoshatidylinositol transfer protein, PITP | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Neurotrophin | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| MSP-like | 0 | Direct |
| DLC | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Chromo domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Variant RING domain | 0 | Direct |
| U-box | 0 | Direct |
| MIT domain | 0 | Direct |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| Plakophilin 1 helical region | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| Alanine racemase-like, N-terminal domain | 0 | Direct |
| Other IPT/TIG domains | 0 | Direct |
| RPR domain (SMART 00582 ) | 0 | Direct |
| PR-1-like | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Ephrin receptor ligand binding domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| GAT domain | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| UBC-related | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | Direct |
| MATH domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| SMAD domain | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| Arrestin/Vps26-like | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| ZZ domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| LEM domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| WGR domain | 0 | Direct |
| DIX domain | 0 | Direct |
| BAR domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| CAT-like | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| Subtilases | 0 | Direct |
| Noggin | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Eukaryotic ODC-like | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| NAP-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | Direct |
| Nitrogenase iron protein-like | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| SEA domain | 0 | Direct |
| Phosducin | 0 | Direct |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| Carboxylesterase/thioesterase 1 | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| SPRY domain | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| PAZ domain | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| HCP-like | 0 | Direct |
| A20-like zinc finger | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Domain G2 of nidogen-1 | 0 | Direct |
| Carboxylesterase | 0 | Direct |
| Neutral endopeptidase (neprilysin) | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| Putative glucosidase YicI, domain 3 | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| MAPEG domain | 0 | Direct |
| ECR1 N-terminal domain-like | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| THAP domain | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| BAG domain | 0 | Direct |
| Occludin/ELL domain | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Synatpobrevin N-terminal domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| P4 origin-binding domain-like | 0 | Direct |
| Troponin I | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| Retinol binding protein-like | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| Connexin43 | 0 | Direct |
| UBX domain | 0 | Direct |
| L domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Crystallins/Ca-binding development proteins | 0 | Direct |
| BEACH domain | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Ribosomal protein L3 | 0 | Direct |
| AAT-like | 0 | Direct |
| Lectin leg-like | 0 | Direct |
| Chromo barrel domain | 0 | Direct |
| BSD domain | 0 | Direct |
| Malic enzyme N-domain | 0 | Direct |
| TRAPP components | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Cryptochrome/photolyase, N-terminal domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Ras GEF | 0 | Direct |
| Crisp domain | 0 | Direct |
| Steroid-binding domain | 0 | Direct |
| Ran-binding domain | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| DJ-1/PfpI | 0 | Direct |
| Noncollagenous (NC1) domain of collagen IV | 0 | Direct |
| Transferrin | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| Nop domain | 0 | Direct |
| LysM domain | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Fibroblast growth factors (FGF) | 0 | Direct |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | Direct |
| Synuclein | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Ephrin ectodomain | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Prokaryotic proteases | 0 | Direct |
| Calnexin/calreticulin | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Cullin repeat | 0 | Direct |
| Transcriptional factor tubby, C-terminal domain | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| RUN domain | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| AraD-like aldolase/epimerase | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| GDI-like N domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | Direct |
| B56-like | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Aldo-keto reductases (NADP) | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Reductases | 0 | Direct |
| Tudor domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Pseudouridine synthase RsuA/RluD | 0 | Direct |
| FF domain | 0 | Direct |
| Canonical RBD | 0.004573 | Inherited |
| Tandem AAA-ATPase domain | 0.01276 | Inherited |
| Protein kinases, catalytic subunit | 0.02174 | Inherited |
| Growth factor receptor domain | 0.06928 | Inherited |
| HMG-box | 0.1018 | Inherited |
| Extended AAA-ATPase domain | 0.1153 | Inherited |
| Motor proteins | 0.1376 | Inherited |
| Second domain of FERM | 0.1894 | Inherited |
| Plexin repeat | 0.2014 | Inherited |
| LIM domain | 0.2143 | Inherited |
| Laminin G-like module | 0.2277 | Inherited |
| PHD domain | 0.2353 | Inherited |
| G proteins | 0.2424 | Inherited |
| WD40-repeat | 0.243 | Inherited |
| F-box domain | 0.324 | Inherited |
| Forkhead DNA-binding domain | 0.3528 | Inherited |
| Tubulin, GTPase domain | 0.4028 | Inherited |
| Tubulin, C-terminal domain | 0.4028 | Inherited |
| Myosin rod fragments | 0.4518 | Inherited |
| ALDH-like | 0.4518 | Inherited |
| Proteasome subunits | 0.4785 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.5045 | Inherited |
| I set domains | 0.5051 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.5335 | Inherited |
| 28-residue LRR | 0.5627 | Inherited |
| Voltage-gated potassium channels | 0.5674 | Inherited |
| GABA-aminotransferase-like | 0.5952 | Inherited |
| Glutathione peroxidase-like | 0.5952 | Inherited |
| CCCH zinc finger | 0.6373 | Inherited |
| Intermediate filament protein, coiled coil region | 0.6777 | Inherited |
| Tropomyosin | 0.6848 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.6998 | Inherited |
| Hairy Orange domain | 0.6998 | Inherited |
| Leukotriene A4 hydrolase catalytic domain | 0.6998 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.7297 | Inherited |
| Fibronectin type III | 0.7358 | Inherited |
| Class I aldolase | 0.7795 | Inherited |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.7795 | Inherited |
| Calmodulin-like | 0.7818 | Inherited |
| Parvalbumin | 0.8216 | Inherited |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0.8621 | Inherited |
| POU-specific domain | 0.9236 | Inherited |
| SOCS box-like | 0.9599 | Inherited |
| Eukaryotic proteases | 0.9978 | Inherited |
| TSP-1 type 1 repeat | 0.999 | Inherited |
| SH2 domain | 1 | Inherited |
| Homeodomain | 1 | Inherited |
| Transforming growth factor (TGF)-beta | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| Classic zinc finger, C2H2 | 1 | Inherited |
| Tetramerization domain of potassium channels | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this XA term (Not in SPXA)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| UBC-like | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Crisp domain-like | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Dimeric alpha+beta barrel | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| Hook domain | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| TRAF domain-like | 0 | DIRECT |
| Actin-crosslinking proteins | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| Globin-like | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| Proton glutamate symport protein | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| gamma-Crystallin-like | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Enolase C-terminal domain-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| SRCR-like | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Cryptochrome/photolyase, N-terminal domain | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| LCCL domain | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| DLC | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Tubby C-terminal domain-like | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| NAP-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Cupredoxins | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Cyclin-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| FnI-like domain | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| MHC antigen-recognition domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| RNA-binding domain, RBD | 0.002602 | INHERITED FROM: testis || pharyngeal arch || gonad || peripheral retina || vegetal pole || eye || intestine || hindbrain || forebrain || pharyngeal region |
| ARM repeat | 0.002654 | INHERITED FROM: testis || gonad || trunk || trunk region |
| P-loop containing nucleoside triphosphate hydrolases | 0.01149 | INHERITED FROM: testis || gonad |
| Protein kinase-like (PK-like) | 0.02542 | INHERITED FROM: animal hemisphere || pharyngeal region || head mesoderm |
| Growth factor receptor domain | 0.0439 | INHERITED FROM: tail tip || heart || coelom |
| WD40 repeat-like | 0.09158 | INHERITED FROM: testis || gonad || trunk || intestine || trunk region |
| Ubiquitin-like | 0.09291 | INHERITED FROM: brain || head region || head |
| HMG-box | 0.1016 | INHERITED FROM: pharyngeal arch || splanchnocranium || midbrain-hindbrain boundary || endocardium || hindbrain || forebrain || optic field || pharyngeal region || endocardial tube |
| Actin-like ATPase domain | 0.1016 | INHERITED FROM: jaw muscle || pancreas || cranial muscle || heart || head somite |
| "Winged helix" DNA-binding domain | 0.1102 | INHERITED FROM: pharyngeal arch || visceral pouch || animal hemisphere || tail fin || eye || stomach || tail tip || optic field || pharyngeal region || head mesoderm || intersomitic region || periocular region |
| Ribonuclease H-like | 0.1226 | INHERITED FROM: testis || gonad || trunk || trunk region |
| Galactose-binding domain-like | 0.1241 | INHERITED FROM: optic nerve |
| PLP-dependent transferases | 0.1667 | INHERITED FROM: intestine |
| Second domain of FERM | 0.1667 | INHERITED FROM: cephalic nerve |
| Plexin repeat | 0.2005 | INHERITED FROM: branchial arch || periocular region |
| NAD(P)-binding Rossmann-fold domains | 0.2837 | INHERITED FROM: trunk || intestine || trunk region || viscus |
| GST C-terminal domain-like | 0.3019 | INHERITED FROM: tail region |
| F-box domain | 0.3226 | INHERITED FROM: animal hemisphere |
| Tudor/PWWP/MBT | 0.3379 | INHERITED FROM: testis || gonad |
| Tubulin nucleotide-binding domain-like | 0.3807 | INHERITED FROM: vegetal hemisphere || vagus nerve || trigeminal nerve || facial nerve || glossopharyngeal nerve || intersomitic neuron |
| Thioredoxin-like | 0.3965 | INHERITED FROM: tail || early proximal tubule || tail region |
| Tubulin C-terminal domain-like | 0.4019 | INHERITED FROM: vegetal hemisphere || vagus nerve || trigeminal nerve || facial nerve || glossopharyngeal nerve || intersomitic neuron |
| Voltage-gated potassium channels | 0.4379 | INHERITED FROM: optic nerve || optic disc || retinal inner plexiform layer || retinal ganglion cell layer || retinal neural layer || cephalic nerve |
| ALDH-like | 0.452 | INHERITED FROM: intestine |
| TIMP-like | 0.4776 | INHERITED FROM: optic field |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.5403 | INHERITED FROM: hypothalamus || zona limitans intrathalamica || basal forebrain || midbrain || ventral septum || basal ganglion || septum || pretectum || prosomere 4 || striatum || subpallium || diencephalon || anterior hypothalamus || ventrolateral thalamic nucleus || thalamus || preoptic area || amygdala || medial septum || hindbrain || forebrain || lateral septum || optic tectum || central nucleus of the thalamus || proximal tubule branch || prosomere || intersomitic region || ventral pallium || lateral pallium |
| PH domain-like | 0.5498 | INHERITED FROM: brain |
| SAM/Pointed domain | 0.5729 | INHERITED FROM: trunk vasculature |
| Tropomyosin | 0.6167 | INHERITED FROM: myocardium || left atrium || outflow tract || cardiac atrium |
| Translation proteins SH3-like domain | 0.6301 | INHERITED FROM: pancreas |
| CCCH zinc finger | 0.6389 | INHERITED FROM: animal pole |
| Leukotriene A4 hydrolase N-terminal domain | 0.6652 | INHERITED FROM: pancreas |
| GroEL apical domain-like | 0.6652 | INHERITED FROM: tail region |
| Intermediate filament protein, coiled coil region | 0.6795 | INHERITED FROM: optic nerve || tail || vestibulocochlear nerve || medulla oblongata || retinal inner plexiform layer || tail region || ventricular zone || retinal inner nuclear layer || retinal ganglion cell layer || nucleus reticularis inferior || retinal ganglion cell || midbrain tegmentum || retinal neural layer || cephalic nerve |
| p53-like transcription factors | 0.6795 | INHERITED FROM: pharyngeal arch || myocardium || chondrocranium || branchial arch skeleton || lower jaw || eye || ceratohyal || pharyngeal region || facial nerve || heart || Meckel's cartilage |
| Orange domain-like | 0.7032 | INHERITED FROM: midbrain || eye || tail tip || pharyngeal region || chordoneural hinge || heart || coelom |
| GroEL equatorial domain-like | 0.7032 | INHERITED FROM: tail || tail region |
| Fibronectin type III | 0.7272 | INHERITED FROM: retinal inner nuclear layer || retinal ganglion cell layer || retinal neural layer |
| HLH, helix-loop-helix DNA-binding domain | 0.7318 | INHERITED FROM: photoreceptor layer || tail bud || pharyngeal arch || midbrain || trunk musculature || hypaxial muscle || cranium || hyoid head muscle || tail fin || eye || hindbrain || retinal inner plexiform layer || stomach || cranial muscle || tail tip || ventricular zone || retinal inner nuclear layer || m. interhyoideus || musculature of face || head vasculature || forebrain || retinal ganglion cell layer || retinal outer nuclear layer || optic field || pharyngeal region || olfactory region || chordoneural hinge || heart || coelom || cranial ganglion || intersomitic region || retinal stem cell region || periocular region |
| SMAD/FHA domain | 0.7677 | INHERITED FROM: endocardium || heart |
| EF-hand | 0.7728 | INHERITED FROM: left atrium || right atrium || cardiac ventricle || cardiac atrium |
| Troponin coil-coiled subunits | 0.7809 | INHERITED FROM: heart |
| EGF/Laminin | 0.7882 | INHERITED FROM: heart |
| Myosin rod fragments | 0.8051 | INHERITED FROM: musculature of face |
| SET domain | 0.8091 | INHERITED FROM: hindbrain |
| Translational machinery components | 0.8226 | INHERITED FROM: pancreas |
| FYVE/PHD zinc finger | 0.8299 | INHERITED FROM: testis || gonad |
| SOCS box-like | 0.9605 | INHERITED FROM: tail |
| lambda repressor-like DNA-binding domains | 0.989 | INHERITED FROM: pronephric tubule || proximal tubule || early distal tubule || distal tubule || late distal tubule |
| TSP-1 type 1 repeat | 0.9967 | INHERITED FROM: rectal diverticulum |
| Cystine-knot cytokines | 1 | INHERITED FROM: trunk vasculature || pharyngeal arch || branchial arch 2 || animal hemisphere || vegetal hemisphere || head mesenchyme || branchial arch 3 || head mesoderm || dorsal aorta || heart || periocular region |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: hypothalamus || basal forebrain || basal ganglion || granule cell layer of the olfactory bulb || septum || striatum || diencephalon || anterior hypothalamus || medial pallium || preoptic area || amygdala || pallium |
| Trypsin-like serine proteases | 1 | INHERITED FROM: pancreas |
| Metalloproteases ("zincins"), catalytic domain | 1 | INHERITED FROM: rectal diverticulum |
| SH2 domain | 1 | INHERITED FROM: animal pole |
| Homeodomain-like | 1 | INHERITED FROM: hypothalamus || pharyngeal pouch || zona limitans intrathalamica || basal forebrain || pronephric tubule || tail bud || pharyngeal arch || midbrain || pronephric nephron || pallidum || telencephalon || periotic region || ventral septum || proximal tubule || cranium || pharyngeal endoderm || visceral pouch || basal ganglion || neurocranium || septum || infundibulum || midbrain-hindbrain boundary || pronephric duct || late proximal tubule || pretectum || optic stalk || dorsal thalamus || early proximal tubule || striatum || subpallium || rhombomere || retinal pigmented epithelium || lower jaw || tail fin || eye || diencephalon || anterior hypothalamus || prethalamus || posterior hypothalamus || mouth || neurenteric canal || medial ganglionic eminence || thalamus || lateral ganglionic eminence || olfactory bulb || preoptic area || amygdala || medial septum || head mesenchyme || hindbrain || early distal tubule || stomach || tail tip || small intestine || ventricular zone || retinal inner nuclear layer || forebrain || retinal ganglion cell layer || lateral septum || posterior wall of neurenteric canal || optic tract || optic field || pallium || pharyngeal region || distal tubule || large intestine || olfactory region || chordoneural hinge || mesonephric duct || proximal tubule branch || heart || prosomere || coelom || intersomitic region || ventral pallium || lateral pallium || cephalic nerve || late distal tubule |
| Immunoglobulin | 1 | INHERITED FROM: spleen || retinal inner nuclear layer |
| POZ domain | 1 | INHERITED FROM: optic disc |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| UBC-like | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Crisp domain-like | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| DNA clamp | 0 | Direct |
| NTF2-like | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| SCP-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Dimeric alpha+beta barrel | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| Hook domain | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| DNase I-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| LigT-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| PRTase-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| TRAF domain-like | 0 | Direct |
| Actin-crosslinking proteins | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Nop domain | 0 | Direct |
| Sema domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| Globin-like | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| L27 domain | 0 | Direct |
| Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| L30e-like | 0 | Direct |
| Synuclein | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| Proton glutamate symport protein | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Sialidases | 0 | Direct |
| FF domain | 0 | Direct |
| gamma-Crystallin-like | 0 | Direct |
| Mss4-like | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Enolase C-terminal domain-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| SRCR-like | 0 | Direct |
| SAP domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| SIS domain | 0 | Direct |
| Cryptochrome/photolyase, N-terminal domain | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Connexin43 | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| LysM domain | 0 | Direct |
| GYF domain | 0 | Direct |
| MIT domain | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| eIF1-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| GroES-like | 0 | Direct |
| LCCL domain | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| GFP-like | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| DLC | 0 | Direct |
| WGR domain-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| ACT-like | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| LEM domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| TGS-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| PapD-like | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| ClpS-like | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| FAS1 domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Tubby C-terminal domain-like | 0 | Direct |
| BSD domain-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| DUSP-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| Stathmin | 0 | Direct |
| SRF-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| 3-carboxy-cis,cis-mucoante lactonizing enzyme | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| NAP-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Ras GEF | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| PR-1-like | 0 | Direct |
| Cupredoxins | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| BAG domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Translation proteins | 0 | Direct |
| Plakin repeat | 0 | Direct |
| KA1-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Cyclin-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Tim10-like | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| FnI-like domain | 0 | Direct |
| HCP-like | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| Pentein | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Annexin | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| HRDC-like | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| ACP-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Insulin-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Nudix | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| ARID-like | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Notch domain | 0 | Direct |
| Cytokine | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| YWTD domain | 0 | Direct |
| Formyltransferase | 0 | Direct |
| MHC antigen-recognition domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| MIR domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| RNA-binding domain, RBD | 0.002602 | Inherited |
| ARM repeat | 0.002654 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.01149 | Inherited |
| Protein kinase-like (PK-like) | 0.02542 | Inherited |
| Growth factor receptor domain | 0.0439 | Inherited |
| WD40 repeat-like | 0.09158 | Inherited |
| Ubiquitin-like | 0.09291 | Inherited |
| HMG-box | 0.1016 | Inherited |
| Actin-like ATPase domain | 0.1016 | Inherited |
| "Winged helix" DNA-binding domain | 0.1102 | Inherited |
| Ribonuclease H-like | 0.1226 | Inherited |
| Galactose-binding domain-like | 0.1241 | Inherited |
| PLP-dependent transferases | 0.1667 | Inherited |
| Second domain of FERM | 0.1667 | Inherited |
| Plexin repeat | 0.2005 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.2837 | Inherited |
| GST C-terminal domain-like | 0.3019 | Inherited |
| F-box domain | 0.3226 | Inherited |
| Tudor/PWWP/MBT | 0.3379 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.3807 | Inherited |
| Thioredoxin-like | 0.3965 | Inherited |
| Tubulin C-terminal domain-like | 0.4019 | Inherited |
| Voltage-gated potassium channels | 0.4379 | Inherited |
| ALDH-like | 0.452 | Inherited |
| TIMP-like | 0.4776 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.5403 | Inherited |
| PH domain-like | 0.5498 | Inherited |
| SAM/Pointed domain | 0.5729 | Inherited |
| Tropomyosin | 0.6167 | Inherited |
| Translation proteins SH3-like domain | 0.6301 | Inherited |
| CCCH zinc finger | 0.6389 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.6652 | Inherited |
| GroEL apical domain-like | 0.6652 | Inherited |
| Intermediate filament protein, coiled coil region | 0.6795 | Inherited |
| p53-like transcription factors | 0.6795 | Inherited |
| Orange domain-like | 0.7032 | Inherited |
| GroEL equatorial domain-like | 0.7032 | Inherited |
| Fibronectin type III | 0.7272 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.7318 | Inherited |
| SMAD/FHA domain | 0.7677 | Inherited |
| EF-hand | 0.7728 | Inherited |
| Troponin coil-coiled subunits | 0.7809 | Inherited |
| EGF/Laminin | 0.7882 | Inherited |
| Myosin rod fragments | 0.8051 | Inherited |
| SET domain | 0.8091 | Inherited |
| Translational machinery components | 0.8226 | Inherited |
| FYVE/PHD zinc finger | 0.8299 | Inherited |
| SOCS box-like | 0.9605 | Inherited |
| lambda repressor-like DNA-binding domains | 0.989 | Inherited |
| TSP-1 type 1 repeat | 0.9967 | Inherited |
| Cystine-knot cytokines | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Trypsin-like serine proteases | 1 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| POZ domain | 1 | Inherited |
(show details)
Supra-domains annotated to this XA term (Not in SPXA)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49854,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | DIRECT |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | DIRECT |
56487,50494
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | DIRECT |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | DIRECT |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | DIRECT |
57196,100895
57196 - EGF/Laminin
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | DIRECT |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | DIRECT |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | DIRECT |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | DIRECT |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
57196,56436
57196 - EGF/Laminin
56436 - C-type lectin-like | 0 | DIRECT |
49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | DIRECT |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
81324,81324
81324 - Voltage-gated potassium channels
81324 - Voltage-gated potassium channels | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56487,56487
56487 - SRCR-like
56487 - SRCR-like | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0 | DIRECT |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
52425,48173
52425 - Cryptochrome/photolyase, N-terminal domain
48173 - Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | DIRECT |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | DIRECT |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | DIRECT |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
48065,103657
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like | 0 | DIRECT |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | DIRECT |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | DIRECT |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | DIRECT |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | DIRECT |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | DIRECT |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | DIRECT |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | DIRECT |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0 | DIRECT |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | DIRECT |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | DIRECT |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
55797,57546
55797 - PR-1-like
57546 - Crisp domain-like | 0 | DIRECT |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47473,57850
47473 - EF-hand
57850 - RING/U-box | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
64268,50044
64268 - PX domain
50044 - SH3-domain | 0 | DIRECT |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
50044,50156
50044 - SH3-domain
50156 - PDZ domain-like | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | DIRECT |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
54236,48366
54236 - Ubiquitin-like
48366 - Ras GEF | 0 | DIRECT |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | DIRECT |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
47661,58038
47661 - t-snare proteins
58038 - SNARE fusion complex | 0 | DIRECT |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57567,57603
57567 - Serine protease inhibitors
57603 - FnI-like domain | 0 | DIRECT |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
49265,49899
49265 - Fibronectin type III
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | DIRECT |
50156,50729
50156 - PDZ domain-like
50729 - PH domain-like | 0 | DIRECT |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
51045,50156
51045 - WW domain
50156 - PDZ domain-like | 0 | DIRECT |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54160,57850
54160 - Chromo domain-like
57850 - RING/U-box | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | DIRECT |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
103657,50044
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | DIRECT |
57184,100895
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | DIRECT |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | DIRECT |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | DIRECT |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | DIRECT |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | DIRECT |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | DIRECT |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | DIRECT |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
48726,56436
48726 - Immunoglobulin
56436 - C-type lectin-like | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | DIRECT |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | DIRECT |
117281,50965
117281 - Kelch motif
50965 - Galactose oxidase, central domain | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.08945 | INHERITED FROM: pharyngeal arch || intestine || viscus || pharyngeal region |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.1241 | INHERITED FROM: testis || gonad || trunk || trunk region |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.1883 | INHERITED FROM: ovary |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.2005 | INHERITED FROM: testis || gonad |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.2955 | INHERITED FROM: hypothalamus || zona limitans intrathalamica || basal forebrain || anterior thalamic nucleus || ventral septum || cranium || basal ganglion || septum || pretectum || prosomere 4 || striatum || subpallium || anterior hypothalamus || ventrolateral thalamic nucleus || thalamus || preoptic area || amygdala || medial septum || hindbrain || bed nucleus of the stria terminalis || forebrain || lateral septum || pallium || optic tectum || central nucleus of the thalamus || dorsal aorta || heart || prosomere || intersomitic region || ventral pallium || lateral pallium || cephalic nerve || medial amygdala |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.4019 | INHERITED FROM: vegetal hemisphere || vagus nerve || trigeminal nerve || facial nerve || glossopharyngeal nerve || intersomitic neuron |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0.452 | INHERITED FROM: pancreas |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0.5961 | INHERITED FROM: retinal inner nuclear layer || retinal ganglion cell layer || retinal neural layer |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.6389 | INHERITED FROM: hypothalamus || intersomitic region |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0.6652 | INHERITED FROM: pancreas |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.7032 | INHERITED FROM: midbrain || eye || tail tip || pharyngeal region || chordoneural hinge || heart || coelom |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.7714 | INHERITED FROM: retinal inner nuclear layer || retinal ganglion cell layer || retinal neural layer |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.9364 | INHERITED FROM: head vasculature || heart || intersomitic region |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 1 | INHERITED FROM: pronephric tubule || retinal ganglion cell layer |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 1 | INHERITED FROM: animal hemisphere || animal pole |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 1 | INHERITED FROM: rectal diverticulum |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 1 | INHERITED FROM: retinal inner nuclear layer |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: hindbrain || otic region |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 1 | INHERITED FROM: animal hemisphere || animal pole |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49854,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | Direct |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | Direct |
56487,50494
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | Direct |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | Direct |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | Direct |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | Direct |
57196,100895
57196 - EGF/Laminin
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | Direct |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | Direct |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | Direct |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | Direct |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | Direct |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | Direct |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | Direct |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | Direct |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
57196,56436
57196 - EGF/Laminin
56436 - C-type lectin-like | 0 | Direct |
49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | Direct |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
81324,81324
81324 - Voltage-gated potassium channels
81324 - Voltage-gated potassium channels | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56487,56487
56487 - SRCR-like
56487 - SRCR-like | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0 | Direct |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
52425,48173
52425 - Cryptochrome/photolyase, N-terminal domain
48173 - Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | Direct |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | Direct |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | Direct |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
48065,103657
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like | 0 | Direct |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | Direct |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | Direct |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | Direct |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | Direct |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0 | Direct |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | Direct |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | Direct |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0 | Direct |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | Direct |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | Direct |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
55797,57546
55797 - PR-1-like
57546 - Crisp domain-like | 0 | Direct |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47473,57850
47473 - EF-hand
57850 - RING/U-box | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
64268,50044
64268 - PX domain
50044 - SH3-domain | 0 | Direct |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
50044,50156
50044 - SH3-domain
50156 - PDZ domain-like | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | Direct |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
54236,48366
54236 - Ubiquitin-like
48366 - Ras GEF | 0 | Direct |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | Direct |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
47661,58038
47661 - t-snare proteins
58038 - SNARE fusion complex | 0 | Direct |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57567,57603
57567 - Serine protease inhibitors
57603 - FnI-like domain | 0 | Direct |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | Direct |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
49265,49899
49265 - Fibronectin type III
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | Direct |
50156,50729
50156 - PDZ domain-like
50729 - PH domain-like | 0 | Direct |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | Direct |
51045,50156
51045 - WW domain
50156 - PDZ domain-like | 0 | Direct |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54160,57850
54160 - Chromo domain-like
57850 - RING/U-box | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | Direct |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
103657,50044
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | Direct |
57184,100895
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | Direct |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | Direct |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | Direct |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | Direct |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | Direct |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | Direct |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | Direct |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | Direct |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
48726,56436
48726 - Immunoglobulin
56436 - C-type lectin-like | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | Direct |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | Direct |
117281,50965
117281 - Kelch motif
50965 - Galactose oxidase, central domain | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.08945 | Inherited |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.1241 | Inherited |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.1883 | Inherited |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.2005 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.2955 | Inherited |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.4019 | Inherited |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0.452 | Inherited |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0.5961 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.6389 | Inherited |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0.6652 | Inherited |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.7032 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.7714 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.9364 | Inherited |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 1 | Inherited |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 1 | Inherited |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 1 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 1 | Inherited |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 1 | Inherited |
(show details)
Supra-domains annotated to this XA term (Not in SPXA)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
90257,90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
57196,57196,49899
57196 - EGF/Laminin
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49785,49785,49899
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | DIRECT |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
48726,56436,56436
48726 - Immunoglobulin
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
54160,57850,57845
54160 - Chromo domain-like
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | DIRECT |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
48065,103657,50044
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | DIRECT |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
49562,49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | DIRECT |
57196,49899,57196
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54511,57184,57184
54511 - GFP-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4259 | INHERITED FROM: heart |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0.739 | INHERITED FROM: tail somite || tail tip || pharyngeal region || chordoneural hinge || trunk somite || coelom |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9777 | INHERITED FROM: pharyngeal mesenchyme |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
90257,90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | Direct |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
57196,57196,49899
57196 - EGF/Laminin
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
49785,49785,49899
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | Direct |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | Direct |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
48726,56436,56436
48726 - Immunoglobulin
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | Direct |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
54160,57850,57845
54160 - Chromo domain-like
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | Direct |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
48065,103657,50044
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | Direct |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | Direct |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
49562,49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | Direct |
57196,49899,57196
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54511,57184,57184
54511 - GFP-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.4259 | Inherited |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0.739 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.9777 | Inherited |
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A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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