SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

  Home > Phenotype Ontology > brain

Xenopus ANatomical entity (XAN): brain

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)

Shortest distance to current term (+ for parents, - for children) XA term [XA ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   anatomical structure [XAO:0003000] <11>(577|733) (577|400|163)
+ + + + 4:   anatomical group [XAO:0003001] <2>(414|530) (418|309|134)
+ + + + 4:   whole organism [XAO:0003004] <12>(461|598) (465|335|145)
+ + + + 4:   Xenopus anatomical entity [XAO:0000000] <9>
+ + + 3:   anatomical region [XAO:0003186] <51>(370|484) (374|284|123)
+ + + 3:   multicellular anatomical structure [XAO:0005002] <4>(436|565) (440|325|142)
+ + + 3:   anatomical system [XAO:0003002] <19>(283|382) (289|204|93)
+ + 2:   organism subdivision [XAO:0003013] <11>(375|498) (381|292|126)
+ + 2:   compound organ [XAO:0003041] <8>(332|444) (336|275|125)
+ + 2:   head region [XAO:0000040] <4>(178|245) (183|137|58)
+ + 2:   nervous system [XAO:0000177] <11>(134|201) (141|114|53)
+ 1:   central nervous system [XAO:0000215] <7>(129|191) (135|108|49)
+ 1:   cavitated compound organ [XAO:0003165] <21>(287|395) (292|247|114)
+ 1:   head [XAO:0003024] <22>(178|244) (183|137|58)
0:   brain [XAO:0000010] <14>(79|120) (80|65|28)
- 1:   midbrain [XAO:0000014] <9>(9|10) (9|3|0)
- 1:   hindbrain [XAO:0000015] <7>(10|11) (11|2|1)
- 1:   forebrain [XAO:0000011] <5>(12|12) (13|3|3)
- 1:   brain ventricle [XAO:0004602] <3>(0|0) (0|0|0)
- 1:   astrocyte [XAO:0005131] <1>(0|0) (0|0|0)
- 1:   midbrain-hindbrain boundary [XAO:0000016] <1>(4|5) (4|1|1)
- 1:   pia mater [XAO:0005289] <1>(0|0) (0|0|0)
- 1:   forebrain-midbrain boundary [XAO:0005027](0|0) (0|0|0)
- 1:   metencephalic artery [XAO:0004167](0|0) (0|0|0)
- 1:   metencephalic vein [XAO:0004168](0|0) (0|0|0)
- 1:   neural stem cell [XAO:0005032](0|0) (0|0|0)
- 1:   oligodendrocyte [XAO:0005133](0|0) (0|0|0)
- 1:   stria terminalis [XAO:0005057](0|0) (0|0|0)
- 1:   ventricular zone [XAO:0000021](4|3) (4|0|0)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
ClpS-like0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
PAH2 domain0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Succinyl-CoA synthetase domains0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Sialidases0Direct
USP8 N-terminal domain-like0Direct
Synuclein0Direct
GroEL-intermediate domain like0Direct
Dimeric alpha+beta barrel0Direct
Stathmin0Direct
F1F0 ATP synthase subunit C0Direct
4Fe-4S ferredoxins0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
BRK domain-like0Direct
Clathrin adaptor appendage domain0Direct
Pentein0Direct
HSP40/DnaJ peptide-binding domain0Direct
Families 57/38 glycoside transferase middle domain0Direct
RNase III domain-like0Direct
Moesin tail domain0Direct
BEACH domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
NAP-like0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
GINS helical bundle-like0Direct
HSP90 C-terminal domain0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
PriA/YqbF domain0Direct
alpha-catenin/vinculin-like0Direct
Guanido kinase N-terminal domain0Direct
Ribulose-phoshate binding barrel0Direct
Glycoside hydrolase/deacetylase0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
ACP-like0Direct
Mss4-like0Direct
I/LWEQ domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
A heparin-binding domain0Direct
MAST3 pre-PK domain-like0Direct
PLP-binding barrel0Direct
Sec1/munc18-like (SM) proteins0Direct
Glutamine synthetase/guanido kinase0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
CCHHC domain0Direct
AraD/HMP-PK domain-like0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
SMAD MH1 domain0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
GYF domain0Direct
Hedgehog/DD-peptidase0Direct
TAFH domain-like0Direct
Zn-finger domain of Sec23/240Direct
Hook domain0Direct
Alanine racemase C-terminal domain-like0Direct
Transcription factor STAT-4 N-domain0Direct
DLC0Direct
Nop domain0Direct
SRF-like0Direct
Acyl-CoA binding protein0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
14-3-3 protein0Direct
PH domain-like0.0002482Direct
Ubiquitin-like0.0002655Direct
HMG-box0.004618Inherited
RNA-binding domain, RBD0.01095Inherited
Frizzled cysteine-rich domain0.02091Inherited
HLH, helix-loop-helix DNA-binding domain0.02292Inherited
Orange domain-like0.05031Inherited
Cytokine0.08471Inherited
Homeodomain-like0.09021Inherited
Intermediate filament protein, coiled coil region0.6694Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.8527Inherited
Family A G protein-coupled receptor-like1Inherited

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Stathmin0Direct
Hedgehog (development protein), N-terminal signaling domain0Direct
PreBEACH PH-like domain0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Pumilio repeat0Direct
Phosphoglucomutase, C-terminal domain0Direct
Hook domain0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
I/LWEQ domain0Direct
Cofactor-dependent phosphoglycerate mutase0Direct
SMAD MH1 domain0Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
Linker histone H1/H50Direct
alpha-mannosidase0Direct
Nuclear receptor coactivator interlocking domain0Direct
TAFH domain-like0Direct
Protein-L-isoaspartyl O-methyltransferase0Direct
GS domain0Direct
HCDH C-domain-like0Direct
14-3-3 protein0Direct
HAT/Suf repeat0Direct
DNA gyrase/MutL, second domain0Direct
CUE domain0Direct
gamma-adaptin C-terminal appendage domain-like0Direct
Guanido kinase catalytic domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
F1F0 ATP synthase subunit C0Direct
Gonadodropin/Follitropin0Direct
Transcription factor STAT-4 N-domain0Direct
TRASH domain0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
NIPSNAP0Direct
DNA ligase0Direct
Zn-finger domain of Sec23/240Direct
Glycosyl transferases group 10Direct
Autophagin-like0Direct
Alpha-adaptin ear subdomain-like0Direct
CCHHC domain0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
SRF-like0Direct
Acyl-CoA binding protein0Direct
Sedlin (SEDL)0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
Phoshatidylinositol transfer protein, PITP0Direct
Guanido kinase N-terminal domain0Direct
MSP-like0Direct
DLC0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
alpha-mannosidase, domain 20Direct
Alanine racemase-like, N-terminal domain0Direct
RPR domain (SMART 00582 )0Direct
Ephrin receptor ligand binding domain0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
USP8 N-terminal domain-like0Direct
SMAD domain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
Branched-chain alpha-keto acid dehydrogenase PP module0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
DIX domain0Direct
BRK domain-like0Direct
Moesin tail domain0Direct
MAST3 pre-PK domain-like0Direct
Noggin0Direct
Eukaryotic ODC-like0Direct
HSP40/DnaJ peptide-binding domain0Direct
HSP90 C-terminal domain0Direct
NAP-like0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Cyclin A/CDK2-associated p19, Skp20Direct
4HBT-like0Direct
Sec1/munc18-like (SM) proteins0Direct
alpha-mannosidase, C-terminal domain0Direct
A heparin-binding domain0Direct
PAH2 domain0Direct
alpha-catenin/vinculin0Direct
A20-like zinc finger0Direct
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A0Direct
alpha-ketoacid dehydrogenase kinase, C-terminal domain0Direct
Hsp90 middle domain0Direct
P4 origin-binding domain-like0Direct
1,3-glucuronyltransferase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
BEACH domain0Direct
Cell cycle control phosphatase, catalytic domain0Direct
Chromo barrel domain0Direct
Ran-binding domain0Direct
S-adenosylhomocystein hydrolase0Direct
Transferrin0Direct
Nop domain0Direct
DNA gyrase/MutL, N-terminal domain0Direct
SH3BGR (SH3-binding, glutamic acid-rich protein-like)0Direct
Synuclein0Direct
Cytidylyltransferase0Direct
Anticodon-binding domain of Class II aaRS0Direct
a tRNA synthase domain0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Succinyl-CoA synthetase domains0Direct
AraD-like aldolase/epimerase0Direct
GDI-like N domain0Direct
Clathrin adaptor appendage, alpha and beta chain-specific domain0Direct
B56-like0Direct
Canonical RBD0.00353Inherited
HMG-box0.004581Inherited
Frizzled cysteine-rich domain0.01915Inherited
HLH, helix-loop-helix DNA-binding domain0.02434Inherited
Hairy Orange domain0.04409Inherited
Histone lysine methyltransferases0.05956Inherited
Homeodomain0.1335Inherited
Sema domain0.3175Inherited
Paired domain0.4039Inherited
LIM domain0.4554Inherited
Intermediate filament protein, coiled coil region0.6564Inherited
Classic zinc finger, C2H20.6646Inherited
Tandem AAA-ATPase domain0.8028Inherited
Rhodopsin-like1Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
TAFH domain-like0Direct
Acyl-CoA binding protein0Direct
Hedgehog/DD-peptidase0Direct
PLP-binding barrel0Direct
Zn-finger domain of Sec23/240Direct
Dimeric alpha+beta barrel0Direct
Hook domain0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Nop domain0Direct
F1F0 ATP synthase subunit C0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
4Fe-4S ferredoxins0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
Synuclein0Direct
RNase III domain-like0Direct
Sialidases0Direct
Mss4-like0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
MAST3 pre-PK domain-like0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
Succinyl-CoA synthetase domains0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
GINS helical bundle-like0Direct
SMAD MH1 domain0Direct
GYF domain0Direct
HSP90 C-terminal domain0Direct
Moesin tail domain0Direct
A heparin-binding domain0Direct
USP8 N-terminal domain-like0Direct
DLC0Direct
alpha-catenin/vinculin-like0Direct
Clathrin adaptor appendage domain0Direct
I/LWEQ domain0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
Guanido kinase N-terminal domain0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
CCHHC domain0Direct
Families 57/38 glycoside transferase middle domain0Direct
ClpS-like0Direct
GroEL-intermediate domain like0Direct
BRK domain-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Glycoside hydrolase/deacetylase0Direct
Stathmin0Direct
SRF-like0Direct
Bacterial exopeptidase dimerisation domain0Direct
NAP-like0Direct
Glutamine synthetase/guanido kinase0Direct
Sec1/munc18-like (SM) proteins0Direct
Transcription factor STAT-4 N-domain0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
PAH2 domain0Direct
BEACH domain0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Pentein0Direct
Ribulose-phoshate binding barrel0Direct
AraD/HMP-PK domain-like0Direct
ACP-like0Direct
Nuclear receptor coactivator interlocking domain0Direct
Alanine racemase C-terminal domain-like0Direct
PriA/YqbF domain0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
PH domain-like0.000185Direct
Ubiquitin-like0.0001981Direct
HMG-box0.003573Inherited
RNA-binding domain, RBD0.00859Inherited
Frizzled cysteine-rich domain0.01659Inherited
HLH, helix-loop-helix DNA-binding domain0.01825Inherited
Orange domain-like0.04134Inherited
Cytokine0.07088Inherited
Homeodomain-like0.07576Inherited
SET domain0.2733Inherited
Intermediate filament protein, coiled coil region0.6341Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.8224Inherited
Family A G protein-coupled receptor-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50998,50978
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 50978 - WD40 repeat-like
    		• 0Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
    		• 0Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
    		• 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
    		• 0Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
    		• 0Direct
    47473,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
    		• 0Direct
    51419,50621
  • 51419 - PLP-binding barrel
  • 50621 - Alanine racemase C-terminal domain-like
    		• 0Direct
    49313,49899
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
    		• 0Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
    		• 0Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
    		• 0Direct
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
    		• 0Direct
    57535,49854
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
    		• 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
    		• 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
    		• 0Direct
    49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
    		• 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
    		• 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
    		• 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
    		• 0Direct
    47473,103506
  • 47473 - EF-hand
  • 103506 - Mitochondrial carrier
    		• 0Direct
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
    		• 0Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
    		• 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    56436,57535
  • 56436 - C-type lectin-like
  • 57535 - Complement control module/SCR domain
    		• 0Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
    		• 0Direct
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
    		• 0Direct
    48065,103657
  • 48065 - DBL homology domain (DH-domain)
  • 103657 - BAR/IMD domain-like
    		• 0Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
    		• 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
    		• 0Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
    		• 0Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
    		• 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
    		• 0Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
    		• 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
    		• 0Direct
    50729,81837
  • 50729 - PH domain-like
  • 81837 - BEACH domain
    		• 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
    		• 0Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
    		• 0Direct
    48403,50044
  • 48403 - Ankyrin repeat
  • 50044 - SH3-domain
    		• 0Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
    		• 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
    		• 0Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
    		• 0Direct
    48371,46785
  • 48371 - ARM repeat
  • 46785 - "Winged helix" DNA-binding domain
    		• 0Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
    		• 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
    		• 0Direct
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
    		• 0Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
    		• 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
    		• 0Direct
    54160,57850
  • 54160 - Chromo domain-like
  • 57850 - RING/U-box
    		• 0Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
    		• 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
    		• 0Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
    		• 0Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
    		• 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
    		• 0Direct
    48350,50729
  • 48350 - GTPase activation domain, GAP
  • 50729 - PH domain-like
    		• 0Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
    		• 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
    		• 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
    		• 0Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
    		• 0Direct
    117281,50965
  • 117281 - Kelch motif
  • 50965 - Galactose oxidase, central domain
    		• 0Direct
    103637,103637
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
    		• 0Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
    		• 0.04134Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
    		• 0.478Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
    		• 0.5935Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
    		• 0.6615Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
    		• 0.7114Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
    		• 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
    		• 0Direct
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
    		• 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
    		• 0Direct
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
    		• 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
    		• 0Direct
    57196,57196,49899
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
    		• 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
    		• 0Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
    		• 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
    		• 0Direct
    103637,103637,103637
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
    		• 0Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
    		• 0Direct
    57535,49854,57535
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
    		• 0Direct
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
    		• 0Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
    		• 0Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
    		• 0Direct
    54160,57850,57845
  • 54160 - Chromo domain-like
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
    		• 0Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
    		• 0Direct
    48065,103657,50044
  • 48065 - DBL homology domain (DH-domain)
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
    		• 0Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
    		• 0Direct
    49313,49313,49899
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
    		• 0Direct
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
    		• 0Direct
    57196,49899,57196
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
    		• 0Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
    		• 0.2116Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
    		• 0.3654Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
    		• 0.478Inherited

    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)
    Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

    Please send feedback, comments or questions to superfamily@cs.bris.ac.uk or use the feedback form.

    © Copyright 2013 The SUPERFAMILY authors and Julian Gough.