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Xenopus ANatomical entity (XAN): anatomical group
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this XA term (Not in SDXA)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| ClpS-like | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| KRAB domain (Kruppel-associated box) | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Dimeric alpha+beta barrel | 0 | DIRECT |
| TRAF domain-like | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Orange domain-like | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| NAP-like | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Cyclin-like | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| STAT | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| SRCR-like | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| Cryptochrome/photolyase, N-terminal domain | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| F-box domain | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| MHC antigen-recognition domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Globin-like | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Hook domain | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Enolase C-terminal domain-like | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| 4-helical cytokines | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| RNA-binding domain, RBD | 0.009672 | INHERITED FROM: testis || muscular system || hindbrain || liver and biliary system || thymus || spinal cord || immune system || urogenital system || intestine || endocrine system || genital system || egg || musculoskeletal system || sensory system || central nervous system || eye || gamete |
| PH domain-like | 0.03488 | INHERITED FROM: brain |
| P-loop containing nucleoside triphosphate hydrolases | 0.03784 | INHERITED FROM: testis || urogenital system || genital system |
| ARM repeat | 0.04341 | INHERITED FROM: testis || urogenital system || genital system || egg || central nervous system || male genitalia |
| Ubiquitin-like | 0.07279 | INHERITED FROM: brain || central nervous system |
| WD40 repeat-like | 0.1792 | INHERITED FROM: testis || urogenital system || intestine || genital system |
| HMG-box | 0.2135 | INHERITED FROM: splanchnocranium || hindbrain || cardiovascular system || spinal cord || endocardium || endocardial tube || retinal layer || forebrain || midbrain-hindbrain boundary || sensory system || otic vesicle |
| Tudor/PWWP/MBT | 0.2231 | INHERITED FROM: testis || genital system || male genitalia |
| Voltage-gated potassium channels | 0.239 | INHERITED FROM: retinal ganglion cell layer || nerve || axon || spinal cord || optic disc || retinal inner plexiform layer || cephalic nerve || neuron || optic nerve || retinal neural layer |
| Ribonuclease H-like | 0.2431 | INHERITED FROM: testis || urogenital system || genital system |
| Nucleic acid-binding proteins | 0.2918 | INHERITED FROM: urogenital system || genital system || egg |
| Growth factor receptor domain | 0.3263 | INHERITED FROM: cardiovascular system || spinal cord || neuromere || otic vesicle || urinary system || heart |
| Plexin repeat | 0.3395 | INHERITED FROM: presumptive midbrain-hindbrain boundary || sensory system || otic placode || liver primordium |
| LDL receptor-like module | 0.3703 | INHERITED FROM: hindgut |
| Cadherin-like | 0.4008 | INHERITED FROM: nervous system || central nervous system |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.4009 | INHERITED FROM: thymus || immune system || skeletal muscle |
| NAD(P)-binding Rossmann-fold domains | 0.453 | INHERITED FROM: alimentary system || intestine || anatomical cluster |
| FnI-like domain | 0.4531 | INHERITED FROM: cardiovascular system || circulatory system || somite |
| SMAD/FHA domain | 0.4819 | INHERITED FROM: endocardium |
| Thioredoxin-like | 0.4893 | INHERITED FROM: bone tissue || bone element || skeleton || skeletal tissue || dermal system || early proximal tubule |
| Actin-like ATPase domain | 0.5253 | INHERITED FROM: myocyte || jaw muscle || head somite || cranial muscle || skeletal muscle || pancreas |
| "Winged helix" DNA-binding domain | 0.5282 | INHERITED FROM: anterior ventral blood island || ventral blood island || hemangioblast || neural tube || spinal cord || circulatory system || sensory system || stomach || otic vesicle || eye || hematological system |
| Ras GEF | 0.5343 | INHERITED FROM: retinal inner plexiform layer || retinal outer plexiform layer |
| Tubulin nucleotide-binding domain-like | 0.5343 | INHERITED FROM: epidermal cell || trigeminal nerve || spinal neuron || facial nerve || vagus nerve || neuron || glossopharyngeal nerve || dermal system || epidermis || intersomitic neuron |
| Tubulin C-terminal domain-like | 0.5569 | INHERITED FROM: epidermal cell || trigeminal nerve || spinal neuron || facial nerve || vagus nerve || neuron || glossopharyngeal nerve || dermal system || epidermis || intersomitic neuron |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.5601 | INHERITED FROM: preoptic area || striatum || hindbrain || basal ganglion || prosomere || ventral pallium || ventral septum || cardiovascular system || basal forebrain || spinal cord || thalamus || subpallium || anterior hypothalamus || pretectum || neural nucleus || ventrolateral thalamic nucleus || forebrain || amygdala || septum || medial septum || liver diverticulum || midbrain || optic tectum || proximal tubule branch || neuromere || diencephalon || zona limitans intrathalamica || hypothalamus || lateral septum || hematological system |
| Clavaminate synthase-like | 0.603 | INHERITED FROM: late distal tubule || late proximal tubule |
| TIMP-like | 0.6265 | INHERITED FROM: cardiovascular system || foregut |
| SAM/Pointed domain | 0.6455 | INHERITED FROM: trunk vasculature |
| PLP-dependent transferases | 0.6532 | INHERITED FROM: intestine || anatomical cluster |
| EF-hand | 0.6601 | INHERITED FROM: right atrium || myocyte || cardiac ventricle || cardiac atrium || left atrium |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.6776 | INHERITED FROM: muscular system || muscle || skeletal muscle |
| Acyl-CoA dehydrogenase NM domain-like | 0.6776 | INHERITED FROM: muscular system || muscle || skeletal muscle |
| Snake toxin-like | 0.6776 | INHERITED FROM: cardiovascular system || artery || aorta || circulatory system || dorsal aorta || trunk vasculature || hematological system || heart |
| EGF/Laminin | 0.7004 | INHERITED FROM: spinal cord || floor plate || heart |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.7583 | INHERITED FROM: egg |
| Translation proteins SH3-like domain | 0.7598 | INHERITED FROM: muscular system || muscle || thymus || immune system || skeletal element || endocrine system || bone tissue || bone element || musculoskeletal system || skeletal tissue || skeletal muscle || pancreas |
| GroEL apical domain-like | 0.7882 | INHERITED FROM: muscular system || muscle || thymus || immune system || dermal system || anterior dorsal lateral plate region || skeletal muscle || skin || hematological system |
| Leukotriene A4 hydrolase N-terminal domain | 0.7882 | INHERITED FROM: pancreas |
| Tropomyosin | 0.7908 | INHERITED FROM: dermomyotome || myocyte || myocardium || outflow tract || cardiac atrium || myotome || left atrium |
| GroEL equatorial domain-like | 0.8183 | INHERITED FROM: muscular system || muscle || thymus || immune system || endocrine system || musculoskeletal system || dermal system || anterior dorsal lateral plate region || skeletal muscle || skin || hematological system |
| GST C-terminal domain-like | 0.8266 | INHERITED FROM: dermal system |
| lambda repressor-like DNA-binding domains | 0.9123 | INHERITED FROM: presumptive midbrain-hindbrain boundary || neural tube || spinal cord || late distal tubule || early distal tubule || pronephric tubule || proximal tubule || neuron || distal tubule |
| FYVE/PHD zinc finger | 0.9426 | INHERITED FROM: testis |
| Fibronectin type III | 0.9859 | INHERITED FROM: retinal ganglion cell layer || retinal inner nuclear layer || retinal neural layer |
| Trypsin-like serine proteases | 1 | INHERITED FROM: pancreas |
| gamma-Crystallin-like | 1 | INHERITED FROM: lens |
| Homeodomain-like | 1 | INHERITED FROM: preoptic area || presumptive midbrain-hindbrain boundary || larval alimentary system || mouth primordium || hindbrain || retinal pigmented epithelium || pronephric duct || basal ganglion || second pancreatic bud || olfactory region || neural tube || prosomere || pharynx || ventral pallium || retinal ganglion cell layer || small intestine || nerve || ventral septum || neurenteric canal || cardiovascular system || basal forebrain || ventricular zone || spinal cord || late distal tubule || thalamus || posterior neural tube || subpallium || anterior hypothalamus || respiratory system || chordoneural hinge || late proximal tubule || pretectum || optic stalk || mesonephric duct || posterior wall of neurenteric canal || eye primordium || lower jaw || early distal tubule || large intestine || medial ganglionic eminence || left lymph heart || enteric nervous system || neural nucleus || pronephric tubule || nervous system || neurocranium || forebrain || amygdala || circulatory system || septum || prethalamus || caudal presomitic mesoderm || lateral ganglionic eminence || cranium || cartilage element || retinal inner nuclear layer || thyroid || proliferative region || midbrain-hindbrain boundary || presomitic mesoderm || medial septum || proximal tubule || pallium || anterior neural tube || optic tract || optic vesicle || posterior hypothalamus || sensory system || rhombomere || midbrain || stomach || otic placode || pronephric nephron || lymphatic system || gut epithelium || proximal tubule branch || cephalic nerve || hindlimb digit || neuron || neuromere || lateral pallium || infundibulum || pallidum || diencephalon || hindgut || peripheral nervous system || telencephalon || early proximal tubule || zona limitans intrathalamica || otic vesicle || hypothalamus || lateral septum || eye || cartilage tissue || distal tubule || embryonic kidney || midgut || ganglion || rostral presomitic mesoderm || skeletal subdivision || olfactory bulb || foregut || digit || heart || dorsal thalamus || right lymph heart || profundus ganglion |
| TSP-1 type 1 repeat | 1 | INHERITED FROM: rectal diverticulum |
| C-type lectin-like | 1 | INHERITED FROM: respiratory system |
| POZ domain | 1 | INHERITED FROM: axon || optic disc |
| Cystine-knot cytokines | 1 | INHERITED FROM: mouth primordium || neural tube || cardiovascular system || secondary heart field || circulatory system || primary heart field || dorsal aorta || trunk vasculature || appendicular skeleton || hindlimb digit || digit || heart |
| p53-like transcription factors | 1 | INHERITED FROM: Meckel's cartilage || cardiovascular system || ceratohyal || lung bud || lower jaw || myocardium || primary heart field || cartilage element || facial nerve || sensory system || lung primordium || neuron || chondrocranium || cartilage tissue || skeletal subdivision || foregut || heart || branchial arch skeleton |
| Metalloproteases ("zincins"), catalytic domain | 1 | INHERITED FROM: rectal diverticulum |
| Kazal-type serine protease inhibitors | 1 | INHERITED FROM: spinal cord || floor plate |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: preoptic area || striatum || basal ganglion || basal forebrain || melanophore || anterior hypothalamus || neural nucleus || amygdala || granule cell layer of the olfactory bulb || septum || pallium || diencephalon || hypothalamus || pigment cell || medial pallium |
| Myosin rod fragments | 1 | INHERITED FROM: musculature of face |
| Intermediate filament protein, coiled coil region | 1 | INHERITED FROM: medulla oblongata || retinal ganglion cell layer || nerve || retinal ganglion cell || ventricular zone || spinal neuron || neural nucleus || retinal inner nuclear layer || retinal inner plexiform layer || cephalic nerve || neuron || dermal system || peripheral nervous system || epidermis || midbrain tegmentum || optic nerve || spinal ganglion || ganglion || gustatory system |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| ClpS-like | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Annexin | 0 | Direct |
| SCP-like | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| LysM domain | 0 | Direct |
| SAP domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Aldolase | 0 | Direct |
| GroES-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| KRAB domain (Kruppel-associated box) | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Sialidases | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| LigT-like | 0 | Direct |
| Synuclein | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| SNARE-like | 0 | Direct |
| KA1-like | 0 | Direct |
| GFP-like | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Dimeric alpha+beta barrel | 0 | Direct |
| TRAF domain-like | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| PRTase-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| MIT domain | 0 | Direct |
| Stathmin | 0 | Direct |
| HCP-like | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Tim10-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| Pentein | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Orange domain-like | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| L27 domain | 0 | Direct |
| BEACH domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| RGC domain-like | 0 | Direct |
| Flavoproteins | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| NAP-like | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Sema domain | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| L30e-like | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Cyclin-like | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| STAT | 0 | Direct |
| DNase I-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| ARID-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| DUSP-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Caspase-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| MIR domain | 0 | Direct |
| eIF4e-like | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| ACP-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
| Trefoil | 0 | Direct |
| SRCR-like | 0 | Direct |
| Mss4-like | 0 | Direct |
| YWTD domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| DNA clamp | 0 | Direct |
| Nudix | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Translational machinery components | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| BAG domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| GLA-domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| FAS1 domain | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| Cryptochrome/photolyase, N-terminal domain | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| PX domain | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| FF domain | 0 | Direct |
| F-box domain | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| ACT-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| MHC antigen-recognition domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| TGS-like | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| WGR domain-like | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Globin-like | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| CCHHC domain | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| Connexin43 | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| SIS domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Histone-fold | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Polo-box domain | 0 | Direct |
| PAZ domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| PapD-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| ALDH-like | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Plakin repeat | 0 | Direct |
| BSD domain-like | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| GYF domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Hook domain | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Enolase C-terminal domain-like | 0 | Direct |
| UBC-like | 0 | Direct |
| 4-helical cytokines | 0 | Direct |
| DLC | 0 | Direct |
| Nop domain | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Notch domain | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| Insulin-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| SRF-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Bromodomain | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Cytokine | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| LEM domain | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| eIF1-like | 0 | Direct |
| Translation proteins | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| PEBP-like | 0 | Direct |
| RNA-binding domain, RBD | 0.009672 | Inherited |
| PH domain-like | 0.03488 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.03784 | Inherited |
| ARM repeat | 0.04341 | Inherited |
| Ubiquitin-like | 0.07279 | Inherited |
| WD40 repeat-like | 0.1792 | Inherited |
| HMG-box | 0.2135 | Inherited |
| Tudor/PWWP/MBT | 0.2231 | Inherited |
| Voltage-gated potassium channels | 0.239 | Inherited |
| Ribonuclease H-like | 0.2431 | Inherited |
| Nucleic acid-binding proteins | 0.2918 | Inherited |
| Growth factor receptor domain | 0.3263 | Inherited |
| Plexin repeat | 0.3395 | Inherited |
| LDL receptor-like module | 0.3703 | Inherited |
| Cadherin-like | 0.4008 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.4009 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.453 | Inherited |
| FnI-like domain | 0.4531 | Inherited |
| SMAD/FHA domain | 0.4819 | Inherited |
| Thioredoxin-like | 0.4893 | Inherited |
| Actin-like ATPase domain | 0.5253 | Inherited |
| "Winged helix" DNA-binding domain | 0.5282 | Inherited |
| Ras GEF | 0.5343 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.5343 | Inherited |
| Tubulin C-terminal domain-like | 0.5569 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.5601 | Inherited |
| Clavaminate synthase-like | 0.603 | Inherited |
| TIMP-like | 0.6265 | Inherited |
| SAM/Pointed domain | 0.6455 | Inherited |
| PLP-dependent transferases | 0.6532 | Inherited |
| EF-hand | 0.6601 | Inherited |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.6776 | Inherited |
| Acyl-CoA dehydrogenase NM domain-like | 0.6776 | Inherited |
| Snake toxin-like | 0.6776 | Inherited |
| EGF/Laminin | 0.7004 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.7583 | Inherited |
| Translation proteins SH3-like domain | 0.7598 | Inherited |
| GroEL apical domain-like | 0.7882 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.7882 | Inherited |
| Tropomyosin | 0.7908 | Inherited |
| GroEL equatorial domain-like | 0.8183 | Inherited |
| GST C-terminal domain-like | 0.8266 | Inherited |
| lambda repressor-like DNA-binding domains | 0.9123 | Inherited |
| FYVE/PHD zinc finger | 0.9426 | Inherited |
| Fibronectin type III | 0.9859 | Inherited |
| Trypsin-like serine proteases | 1 | Inherited |
| gamma-Crystallin-like | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
| TSP-1 type 1 repeat | 1 | Inherited |
| C-type lectin-like | 1 | Inherited |
| POZ domain | 1 | Inherited |
| Cystine-knot cytokines | 1 | Inherited |
| p53-like transcription factors | 1 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 1 | Inherited |
| Kazal-type serine protease inhibitors | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Myosin rod fragments | 1 | Inherited |
| Intermediate filament protein, coiled coil region | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this XA term (Not in SDXA)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| RGC domain | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Hedgehog (development protein), N-terminal signaling domain | 0 | DIRECT |
| Ferritin | 0 | DIRECT |
| GRAM domain | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| ELL N2 domain-like | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| PreBEACH PH-like domain | 0 | DIRECT |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| ENTH domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| VWC domain | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| Nucleotide and nucleoside kinases | 0 | DIRECT |
| Elongation factors | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| APC10-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| Hook domain | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| MBT repeat | 0 | DIRECT |
| Complement components | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Fibronectin type II module | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| Third domain of FERM | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Mib/herc2 domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| Cofactor-dependent phosphoglycerate mutase | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| Calcium ATPase, transmembrane domain M | 0 | DIRECT |
| MHC antigen-recognition domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Linker histone H1/H5 | 0 | DIRECT |
| E2F dimerization segment | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Parvalbumin | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| Cold shock DNA-binding domain-like | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| RWD domain | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| Cytochrome b5 | 0 | DIRECT |
| Thrombospondin C-terminal domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| F-box domain | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| IMD domain | 0 | DIRECT |
| Cell cycle transcription factor e2f-dp | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Protein-L-isoaspartyl O-methyltransferase | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| GS domain | 0 | DIRECT |
| Nucleosome core histones | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| CAD domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| Glucose 6-phosphate dehydrogenase-like | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Crotonase-like | 0 | DIRECT |
| TBP-associated factors, TAFs | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| Methyl-CpG-binding domain, MBD | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| RUNT domain | 0 | DIRECT |
| CUE domain | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| gamma-adaptin C-terminal appendage domain-like | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Globins | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| UDPGT-like | 0 | DIRECT |
| Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| Gonadodropin/Follitropin | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| TRASH domain | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| Thioltransferase | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| NIPSNAP | 0 | DIRECT |
| Cyclophilin (peptidylprolyl isomerase) | 0 | DIRECT |
| DNA ligase | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| Pointed domain | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| DNA/RNA non-specific endonuclease | 0 | DIRECT |
| Myeloperoxidase-like | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Phenylalanine metabolism regulatory domain | 0 | DIRECT |
| MPP-like | 0 | DIRECT |
| Autophagin-like | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Fibronectin type I module | 0 | DIRECT |
| Netrin-like domain (NTR/C345C module) | 0 | DIRECT |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| Alpha-adaptin ear subdomain-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| L-aminoacid/polyamine oxidase | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| KRAB domain (Kruppel-associated box) | 0 | DIRECT |
| Caspase catalytic domain | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| SIAH, seven in absentia homolog | 0 | DIRECT |
| GABARAP-like | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| C1 set domains (antibody constant domain-like) | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| Sedlin (SEDL) | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Prohormone convertase 1 pro-domain | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| (Glycosyl)asparaginase | 0 | DIRECT |
| LON domain-like | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Extradiol dioxygenases | 0 | DIRECT |
| ATP-dependent DNA ligase catalytic domain | 0 | DIRECT |
| Phoshatidylinositol transfer protein, PITP | 0 | DIRECT |
| D-aminoacid oxidase-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Neurotrophin | 0 | DIRECT |
| MSP-like | 0 | DIRECT |
| DLC | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Chromo domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Variant RING domain | 0 | DIRECT |
| U-box | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Plakophilin 1 helical region | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| F-box associated region, FBA | 0 | DIRECT |
| Sterol carrier protein, SCP | 0 | DIRECT |
| Alanine racemase-like, N-terminal domain | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| Other IPT/TIG domains | 0 | DIRECT |
| RPR domain (SMART 00582 ) | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Ephrin receptor ligand binding domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| GAT domain | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | DIRECT |
| MATH domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Long-chain cytokines | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| Arrestin/Vps26-like | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| ZZ domain | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| DIX domain | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| Outer arm dynein light chain 1 | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Noggin | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Eukaryotic ODC-like | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| TATA-box binding protein (TBP), C-terminal domain | 0 | DIRECT |
| Hairy Orange domain | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| NAP-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Nitrogenase iron protein-like | 0 | DIRECT |
| 5' nucleotidase-like | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| SEA domain | 0 | DIRECT |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| Carboxylesterase/thioesterase 1 | 0 | DIRECT |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| STAT | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| alpha-catenin/vinculin | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| A20-like zinc finger | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Domain G2 of nidogen-1 | 0 | DIRECT |
| Carboxylesterase | 0 | DIRECT |
| Neutral endopeptidase (neprilysin) | 0 | DIRECT |
| Putative glucosidase YicI, domain 3 | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| MAPEG domain | 0 | DIRECT |
| ECR1 N-terminal domain-like | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| THAP domain | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Occludin/ELL domain | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Synatpobrevin N-terminal domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| P4 origin-binding domain-like | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| Retinol binding protein-like | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| UBX domain | 0 | DIRECT |
| L domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Pseudouridine synthase I TruA | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| Ribosomal protein L3 | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| Lectin leg-like | 0 | DIRECT |
| MHCK/EF2 kinase | 0 | DIRECT |
| Chromo barrel domain | 0 | DIRECT |
| BSD domain | 0 | DIRECT |
| Malic enzyme N-domain | 0 | DIRECT |
| TRAPP components | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| NADPH-cytochrome p450 reductase-like | 0 | DIRECT |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Cryptochrome/photolyase, N-terminal domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Steroid-binding domain | 0 | DIRECT |
| Ran-binding domain | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| DJ-1/PfpI | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| Noncollagenous (NC1) domain of collagen IV | 0 | DIRECT |
| Transferrin | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| RhoGDI-like | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| Fibroblast growth factors (FGF) | 0 | DIRECT |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| Cytochrome p450 reductase N-terminal domain-like | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Prokaryotic proteases | 0 | DIRECT |
| Calnexin/calreticulin | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Exostosin | 0 | DIRECT |
| Gelsolin-like | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| STAT DNA-binding domain | 0 | DIRECT |
| Troponin T | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| RUN domain | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| AraD-like aldolase/epimerase | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| GDI-like N domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | DIRECT |
| B56-like | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| La domain | 0 | DIRECT |
| Aldo-keto reductases (NADP) | 0 | DIRECT |
| Oxysterol-binding protein | 0 | DIRECT |
| HEAT repeat | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| Tudor domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Pseudouridine synthase RsuA/RluD | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Canonical RBD | 0.03156 | INHERITED FROM: testis || muscular system || hindbrain || alimentary system || liver and biliary system || thymus || spinal cord || immune system || urogenital system || nervous system || intestine || endocrine system || genital system || egg || musculoskeletal system || sensory system || central nervous system || eye || anatomical cluster || gamete |
| Tandem AAA-ATPase domain | 0.04157 | INHERITED FROM: testis || hindbrain || ventral blood island || urogenital system || forebrain || genital system || vestibuloauditory system || midbrain || otic vesicle || hematological system |
| I set domains | 0.07237 | INHERITED FROM: retinal ganglion cell layer || spinal cord || retinal inner nuclear layer || optic vesicle |
| WD40-repeat | 0.1767 | INHERITED FROM: testis || urogenital system || intestine || genital system || egg |
| HMG-box | 0.189 | INHERITED FROM: splanchnocranium || hindbrain || cardiovascular system || spinal cord || endocardium || endocardial tube || retinal layer || forebrain || midbrain-hindbrain boundary || sensory system || otic vesicle |
| Plexin repeat | 0.3093 | INHERITED FROM: presumptive midbrain-hindbrain boundary || sensory system || otic placode || liver primordium |
| LIM domain | 0.3239 | INHERITED FROM: prosomere || medial amygdala || ventral septum || cardiovascular system || basal forebrain || bed nucleus of the stria terminalis || thalamus || central nucleus of the thalamus || pretectum || neural nucleus || ventrolateral thalamic nucleus || amygdala || septum || prosomere 4 || anterior thalamic nucleus || neuromere || skeletal system || heart |
| LDL receptor-like module | 0.3376 | INHERITED FROM: hindgut |
| G proteins | 0.3474 | INHERITED FROM: olfactory sensory neuron || primary oogonium || primary spermatogonium || olfactory epithelium |
| Cadherin | 0.379 | INHERITED FROM: nervous system || central nervous system |
| PHD domain | 0.3918 | INHERITED FROM: testis |
| Growth factor receptor domain | 0.4041 | INHERITED FROM: cardiovascular system || spinal cord || sensory system || heart |
| Voltage-gated potassium channels | 0.4739 | INHERITED FROM: axon || optic disc || retinal inner plexiform layer || neuron || optic nerve |
| Extended AAA-ATPase domain | 0.517 | INHERITED FROM: testis || genital system |
| Motor proteins | 0.5182 | INHERITED FROM: musculature of face |
| Tubulin, GTPase domain | 0.519 | INHERITED FROM: epidermal cell || trigeminal nerve || spinal neuron || facial nerve || vagus nerve || neuron || glossopharyngeal nerve || dermal system || epidermis || intersomitic neuron |
| Tubulin, C-terminal domain | 0.519 | INHERITED FROM: epidermal cell || trigeminal nerve || spinal neuron || facial nerve || vagus nerve || neuron || glossopharyngeal nerve || dermal system || epidermis || intersomitic neuron |
| EGF-type module | 0.5309 | INHERITED FROM: spinal cord |
| Proteasome subunits | 0.5881 | INHERITED FROM: muscular system || muscle || thymus || immune system || endocrine system || musculoskeletal system || dermal system || skeletal muscle || skin |
| POU-specific domain | 0.6655 | INHERITED FROM: presumptive midbrain-hindbrain boundary || pronephric duct || neural tube || retinal ganglion cell layer || spinal cord || late distal tubule || early distal tubule || pronephric tubule || proximal tubule || neuron || distal tubule |
| 28-residue LRR | 0.6655 | INHERITED FROM: trunk musculature || epaxial muscle |
| Papain-like | 0.6655 | INHERITED FROM: thymus || immune system || endocrine system |
| GABA-aminotransferase-like | 0.6949 | INHERITED FROM: intestine |
| Glutathione peroxidase-like | 0.6949 | INHERITED FROM: splanchnocranium || eye primordium || early distal tubule || pronephric tubule || bone tissue || cranium || presomitic mesoderm || proximal tubule || bone element || skeletal tissue || pronephric nephron || early proximal tubule || distal tubule || embryonic kidney || foregut |
| Laminin G-like module | 0.701 | INHERITED FROM: spinal cord || female genitalia || ovary |
| Calmodulin-like | 0.7354 | INHERITED FROM: right atrium || cardiac ventricle || ciliated epidermal cell || cardiac atrium || left atrium |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0.737 | INHERITED FROM: retinal ganglion cell layer || retinal inner nuclear layer |
| Tetramerization domain of potassium channels | 0.7746 | INHERITED FROM: retinal ganglion cell layer || axon || optic disc || neuron projection || retinal inner plexiform layer || retinal outer plexiform layer || neuron || optic nerve |
| Leukotriene A4 hydrolase N-terminal domain | 0.7846 | INHERITED FROM: pancreas |
| Leukotriene A4 hydrolase catalytic domain | 0.7846 | INHERITED FROM: pancreas |
| Tropomyosin | 0.812 | INHERITED FROM: dermomyotome || myocyte || myocardium || outflow tract || cardiac atrium || myotome || left atrium |
| Link domain | 0.817 | INHERITED FROM: vestibuloauditory system |
| Erythroid transcription factor GATA-1 | 0.8501 | INHERITED FROM: ventral blood island || cardiovascular system || myocardium || hematopoietic stem cell || liver diverticulum || cardiac progenitor cell || anterior dorsal lateral plate region || hematological system || heart |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.8501 | INHERITED FROM: muscular system || muscle || thymus || immune system || endocrine system || skeletal muscle |
| Multidrug efflux transporter AcrB transmembrane domain | 0.8844 | INHERITED FROM: epidermis |
| Myosin rod fragments | 0.9216 | INHERITED FROM: musculature of face |
| Classic zinc finger, C2H2 | 0.9465 | INHERITED FROM: hindbrain || spinal cord || midbrain |
| Glutathione S-transferase (GST), C-terminal domain | 0.9546 | INHERITED FROM: dermal system |
| Fibronectin type III | 0.9629 | INHERITED FROM: retinal ganglion cell layer || retinal neural layer |
| Forkhead DNA-binding domain | 0.9664 | INHERITED FROM: larval alimentary system || cloaca || olfactory region || neural tube || pronephric nephrostome || thyroid primordium || spinal cord || respiratory system || chordoneural hinge || myocardium || cranium || floor plate || presomitic mesoderm || ciliated epidermal cell || sensory system || esophagus || stomach || hindgut || eye |
| Glutathione S-transferase (GST), N-terminal domain | 0.9697 | INHERITED FROM: dermal system || skin |
| T-box | 0.9697 | INHERITED FROM: cardiovascular system || myocardium || primary heart field || sensory system || heart primordium || foregut || heart |
| Tyrosine-dependent oxidoreductases | 0.9747 | INHERITED FROM: alimentary system || anatomical cluster |
| Intermediate filament protein, coiled coil region | 0.9949 | INHERITED FROM: medulla oblongata || vestibulocochlear nerve || retinal ganglion cell layer || nerve || retinal ganglion cell || ventricular zone || nucleus reticularis inferior || spinal neuron || neural nucleus || retinal inner nuclear layer || retinal inner plexiform layer || cephalic nerve || neuron || dermal system || peripheral nervous system || epidermis || midbrain tegmentum || optic nerve || spinal ganglion || ganglion || gustatory system |
| Homeodomain | 1 | INHERITED FROM: preoptic area || presumptive midbrain-hindbrain boundary || larval alimentary system || mouth primordium || striatum || hindbrain || pronephric duct || basal ganglion || second pancreatic bud || olfactory region || neural tube || prosomere || pharynx || ventral pallium || retinal ganglion cell layer || small intestine || nerve || ventral septum || neurenteric canal || cardiovascular system || basal forebrain || bed nucleus of the stria terminalis || lung bud || ventricular zone || spinal cord || late distal tubule || thalamus || mandibular arch || posterior neural tube || subpallium || anterior hypothalamus || respiratory system || chordoneural hinge || late proximal tubule || pretectum || optic stalk || posterior wall of neurenteric canal || eye primordium || lower jaw || early distal tubule || large intestine || medial ganglionic eminence || left lymph heart || enteric nervous system || neural nucleus || pronephric tubule || neurocranium || forebrain || amygdala || circulatory system || septum || prethalamus || caudal presomitic mesoderm || lateral ganglionic eminence || cranium || cartilage element || retinal inner nuclear layer || proliferative region || midbrain-hindbrain boundary || presomitic mesoderm || medial septum || proximal tubule || pineal gland || pallium || anterior neural tube || posterior hypothalamus || sensory system || rhombomere || midbrain || stomach || otic placode || pronephric nephron || lymphatic system || proximal tubule branch || cephalic nerve || hindlimb digit || neuron || neuromere || lateral pallium || infundibulum || pallidum || diencephalon || hindgut || peripheral nervous system || telencephalon || early proximal tubule || zona limitans intrathalamica || otic vesicle || hypothalamus || lateral septum || eye || cartilage tissue || distal tubule || embryonic kidney || midgut || ganglion || rostral presomitic mesoderm || skeletal subdivision || olfactory bulb || foregut || digit || heart || dorsal thalamus || right lymph heart || roof plate || profundus ganglion |
| TSP-1 type 1 repeat | 1 | INHERITED FROM: rectal diverticulum |
| Eukaryotic proteases | 1 | INHERITED FROM: pancreas |
| Transforming growth factor (TGF)-beta | 1 | INHERITED FROM: mouth primordium || cardiovascular system || aorta || early distal tubule || secondary heart field || circulatory system || primary heart field || dorsal aorta || trunk vasculature || heart primordium || heart |
| Ovomucoid domain III-like | 1 | INHERITED FROM: spinal cord || floor plate |
| Rhodopsin-like | 1 | INHERITED FROM: preoptic area || striatum || basal ganglion || basal forebrain || melanophore || anterior hypothalamus || neural nucleus || amygdala || granule cell layer of the olfactory bulb || septum || pallium || eye photoreceptor cell || diencephalon || hypothalamus || pigment cell || medial pallium |
| Crystallins/Ca-binding development proteins | 1 | INHERITED FROM: lens |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| Stathmin | 0 | Direct |
| RGC domain | 0 | Direct |
| Thiolase-related | 0 | Direct |
| YWTD domain | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Hedgehog (development protein), N-terminal signaling domain | 0 | Direct |
| Ferritin | 0 | Direct |
| GRAM domain | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| ELL N2 domain-like | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| PreBEACH PH-like domain | 0 | Direct |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| MIR domain | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| ARID domain | 0 | Direct |
| ENTH domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| VWC domain | 0 | Direct |
| LeuD-like | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| Nucleotide and nucleoside kinases | 0 | Direct |
| Elongation factors | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| APC10-like | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| 6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| Hook domain | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| DNase I-like | 0 | Direct |
| MBT repeat | 0 | Direct |
| Complement components | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| eIF1-like | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| Formyltransferase | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Fibronectin type II module | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| Third domain of FERM | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| ets domain | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Mib/herc2 domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 0 | Direct |
| Adenain-like | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| Cofactor-dependent phosphoglycerate mutase | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| Calcium ATPase, transmembrane domain M | 0 | Direct |
| MHC antigen-recognition domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | Direct |
| Insulin-like | 0 | Direct |
| MutT-like | 0 | Direct |
| FAS1 domain | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| PUA domain | 0 | Direct |
| Linker histone H1/H5 | 0 | Direct |
| E2F dimerization segment | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Parvalbumin | 0 | Direct |
| Class I aldolase | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| Cold shock DNA-binding domain-like | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| RWD domain | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| HD domain | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| Cytochrome b5 | 0 | Direct |
| Thrombospondin C-terminal domain | 0 | Direct |
| SAP domain | 0 | Direct |
| F-box domain | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| IMD domain | 0 | Direct |
| Cell cycle transcription factor e2f-dp | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Protein-L-isoaspartyl O-methyltransferase | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| GS domain | 0 | Direct |
| Nucleosome core histones | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| CAD domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| Glucose 6-phosphate dehydrogenase-like | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Crotonase-like | 0 | Direct |
| TBP-associated factors, TAFs | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| Fumble-like | 0 | Direct |
| Methyl-CpG-binding domain, MBD | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| RUNT domain | 0 | Direct |
| CUE domain | 0 | Direct |
| NagB-like | 0 | Direct |
| DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| Scavenger receptor cysteine-rich (SRCR) domain | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Prefoldin | 0 | Direct |
| L27 domain | 0 | Direct |
| gamma-adaptin C-terminal appendage domain-like | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Globins | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| UDPGT-like | 0 | Direct |
| Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| Gonadodropin/Follitropin | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| TRASH domain | 0 | Direct |
| Plakin repeat | 0 | Direct |
| Thioltransferase | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| NIPSNAP | 0 | Direct |
| Cyclophilin (peptidylprolyl isomerase) | 0 | Direct |
| DNA ligase | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| Paired domain | 0 | Direct |
| FCH domain | 0 | Direct |
| Pointed domain | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| DNA/RNA non-specific endonuclease | 0 | Direct |
| Myeloperoxidase-like | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Phenylalanine metabolism regulatory domain | 0 | Direct |
| MPP-like | 0 | Direct |
| Autophagin-like | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Fibronectin type I module | 0 | Direct |
| Netrin-like domain (NTR/C345C module) | 0 | Direct |
| Formate/glycerate dehydrogenases, substrate-binding domain | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| Alpha-adaptin ear subdomain-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| CCHHC domain | 0 | Direct |
| IF2B-like | 0 | Direct |
| L-aminoacid/polyamine oxidase | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| SRF-like | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| VHS domain | 0 | Direct |
| Cyclin | 0 | Direct |
| Notch domain | 0 | Direct |
| KRAB domain (Kruppel-associated box) | 0 | Direct |
| Caspase catalytic domain | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| SIAH, seven in absentia homolog | 0 | Direct |
| GABARAP-like | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| Sema domain | 0 | Direct |
| C1 set domains (antibody constant domain-like) | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| Trefoil | 0 | Direct |
| Sedlin (SEDL) | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Prohormone convertase 1 pro-domain | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| PDI-like | 0 | Direct |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
| Annexin | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| (Glycosyl)asparaginase | 0 | Direct |
| LON domain-like | 0 | Direct |
| PX domain | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Extradiol dioxygenases | 0 | Direct |
| ATP-dependent DNA ligase catalytic domain | 0 | Direct |
| Phoshatidylinositol transfer protein, PITP | 0 | Direct |
| D-aminoacid oxidase-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Neurotrophin | 0 | Direct |
| MSP-like | 0 | Direct |
| DLC | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Chromo domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Variant RING domain | 0 | Direct |
| U-box | 0 | Direct |
| MIT domain | 0 | Direct |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Plakophilin 1 helical region | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| F-box associated region, FBA | 0 | Direct |
| Sterol carrier protein, SCP | 0 | Direct |
| Alanine racemase-like, N-terminal domain | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| Other IPT/TIG domains | 0 | Direct |
| RPR domain (SMART 00582 ) | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Ephrin receptor ligand binding domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| GAT domain | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| UBC-related | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0 | Direct |
| MATH domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| SMAD domain | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Long-chain cytokines | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| Arrestin/Vps26-like | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| ZZ domain | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| LEM domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| WGR domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| DIX domain | 0 | Direct |
| BAR domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| CAT-like | 0 | Direct |
| Outer arm dynein light chain 1 | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| Subtilases | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Noggin | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Eukaryotic ODC-like | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| TATA-box binding protein (TBP), C-terminal domain | 0 | Direct |
| Hairy Orange domain | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| ALDH-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| NAP-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| First domain of FERM | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Cyclin A/CDK2-associated p19, Skp2 | 0 | Direct |
| Bromodomain | 0 | Direct |
| Nitrogenase iron protein-like | 0 | Direct |
| 5' nucleotidase-like | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| SEA domain | 0 | Direct |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| Carboxylesterase/thioesterase 1 | 0 | Direct |
| Medium chain acyl-CoA dehydrogenase-like, C-terminal domain | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| STAT | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| PAH2 domain | 0 | Direct |
| alpha-catenin/vinculin | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| PAZ domain | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| HCP-like | 0 | Direct |
| A20-like zinc finger | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Domain G2 of nidogen-1 | 0 | Direct |
| Carboxylesterase | 0 | Direct |
| Neutral endopeptidase (neprilysin) | 0 | Direct |
| Putative glucosidase YicI, domain 3 | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| MAPEG domain | 0 | Direct |
| ECR1 N-terminal domain-like | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| THAP domain | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| BAG domain | 0 | Direct |
| Occludin/ELL domain | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Synatpobrevin N-terminal domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| P4 origin-binding domain-like | 0 | Direct |
| Troponin I | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| Retinol binding protein-like | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| Connexin43 | 0 | Direct |
| UBX domain | 0 | Direct |
| L domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Pseudouridine synthase I TruA | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| Threonyl-tRNA synthetase (ThrRS), second 'additional' domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| BEACH domain | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| Ribosomal protein L3 | 0 | Direct |
| AAT-like | 0 | Direct |
| Lectin leg-like | 0 | Direct |
| MHCK/EF2 kinase | 0 | Direct |
| Chromo barrel domain | 0 | Direct |
| BSD domain | 0 | Direct |
| Malic enzyme N-domain | 0 | Direct |
| TRAPP components | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| NADPH-cytochrome p450 reductase-like | 0 | Direct |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Cryptochrome/photolyase, N-terminal domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Adenylyl and guanylyl cyclase catalytic domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Steroid-binding domain | 0 | Direct |
| Ran-binding domain | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| DJ-1/PfpI | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| Noncollagenous (NC1) domain of collagen IV | 0 | Direct |
| Transferrin | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| RhoGDI-like | 0 | Direct |
| GLA-domain | 0 | Direct |
| Nop domain | 0 | Direct |
| LysM domain | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| Fibroblast growth factors (FGF) | 0 | Direct |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | Direct |
| Synuclein | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| Cytochrome p450 reductase N-terminal domain-like | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Prokaryotic proteases | 0 | Direct |
| Calnexin/calreticulin | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Exostosin | 0 | Direct |
| Gelsolin-like | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| STAT DNA-binding domain | 0 | Direct |
| Troponin T | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| Cullin repeat | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| RUN domain | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| RIKEN cDNA 2310057j16 protein (KIAA1543) | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| AraD-like aldolase/epimerase | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| GDI-like N domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | Direct |
| B56-like | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| La domain | 0 | Direct |
| Aldo-keto reductases (NADP) | 0 | Direct |
| Oxysterol-binding protein | 0 | Direct |
| HEAT repeat | 0 | Direct |
| Reductases | 0 | Direct |
| Tudor domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Pseudouridine synthase RsuA/RluD | 0 | Direct |
| FF domain | 0 | Direct |
| Canonical RBD | 0.03156 | Inherited |
| Tandem AAA-ATPase domain | 0.04157 | Inherited |
| I set domains | 0.07237 | Inherited |
| WD40-repeat | 0.1767 | Inherited |
| HMG-box | 0.189 | Inherited |
| Plexin repeat | 0.3093 | Inherited |
| LIM domain | 0.3239 | Inherited |
| LDL receptor-like module | 0.3376 | Inherited |
| G proteins | 0.3474 | Inherited |
| Cadherin | 0.379 | Inherited |
| PHD domain | 0.3918 | Inherited |
| Growth factor receptor domain | 0.4041 | Inherited |
| Voltage-gated potassium channels | 0.4739 | Inherited |
| Extended AAA-ATPase domain | 0.517 | Inherited |
| Motor proteins | 0.5182 | Inherited |
| Tubulin, GTPase domain | 0.519 | Inherited |
| Tubulin, C-terminal domain | 0.519 | Inherited |
| EGF-type module | 0.5309 | Inherited |
| Proteasome subunits | 0.5881 | Inherited |
| POU-specific domain | 0.6655 | Inherited |
| 28-residue LRR | 0.6655 | Inherited |
| Papain-like | 0.6655 | Inherited |
| GABA-aminotransferase-like | 0.6949 | Inherited |
| Glutathione peroxidase-like | 0.6949 | Inherited |
| Laminin G-like module | 0.701 | Inherited |
| Calmodulin-like | 0.7354 | Inherited |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0.737 | Inherited |
| Tetramerization domain of potassium channels | 0.7746 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.7846 | Inherited |
| Leukotriene A4 hydrolase catalytic domain | 0.7846 | Inherited |
| Tropomyosin | 0.812 | Inherited |
| Link domain | 0.817 | Inherited |
| Erythroid transcription factor GATA-1 | 0.8501 | Inherited |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0.8501 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.8844 | Inherited |
| Myosin rod fragments | 0.9216 | Inherited |
| Classic zinc finger, C2H2 | 0.9465 | Inherited |
| Glutathione S-transferase (GST), C-terminal domain | 0.9546 | Inherited |
| Fibronectin type III | 0.9629 | Inherited |
| Forkhead DNA-binding domain | 0.9664 | Inherited |
| Glutathione S-transferase (GST), N-terminal domain | 0.9697 | Inherited |
| T-box | 0.9697 | Inherited |
| Tyrosine-dependent oxidoreductases | 0.9747 | Inherited |
| Intermediate filament protein, coiled coil region | 0.9949 | Inherited |
| Homeodomain | 1 | Inherited |
| TSP-1 type 1 repeat | 1 | Inherited |
| Eukaryotic proteases | 1 | Inherited |
| Transforming growth factor (TGF)-beta | 1 | Inherited |
| Ovomucoid domain III-like | 1 | Inherited |
| Rhodopsin-like | 1 | Inherited |
| Crystallins/Ca-binding development proteins | 1 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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A presence/absence matrix is generated using protein domain
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if individual trees had been produced. However, this data is extracted from the single
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this XA term (Not in SPXA)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| UBC-like | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Cullin repeat-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| TAFH domain-like | 0 | DIRECT |
| NAD(P)-linked oxidoreductase | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| DNA clamp | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Acyl-CoA binding protein | 0 | DIRECT |
| SCP-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Surp module (SWAP domain) | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| Nitric oxide (NO) synthase oxygenase domain | 0 | DIRECT |
| FMN-linked oxidoreductases | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | DIRECT |
| Dimeric alpha+beta barrel | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| Hook domain | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| F-box domain | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| TNF receptor-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Nucleotide cyclase | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| TRAF domain-like | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Calcium-dependent phosphotriesterase | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| Globin-like | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Eferin C-derminal domain-like | 0 | DIRECT |
| IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Chaperone J-domain | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Flavoproteins | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| Class II aaRS and biotin synthetases | 0 | DIRECT |
| Carbonic anhydrase | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| Orange domain-like | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| P-domain of calnexin/calreticulin | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Enolase C-terminal domain-like | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Ammonium transporter | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Mannose 6-phosphate receptor domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Nucleoplasmin-like core domain | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| SRCR-like | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Cryptochrome/photolyase, N-terminal domain | 0 | DIRECT |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| RGC domain-like | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Connexin43 | 0 | DIRECT |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| STAT | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Transducin (heterotrimeric G protein), gamma chain | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| LysM domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| MIT domain | 0 | DIRECT |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| ATP-dependent DNA ligase DNA-binding domain | 0 | DIRECT |
| RUN domain-like | 0 | DIRECT |
| Band 7/SPFH domain | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| GroES-like | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| GFP-like | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| DLC | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| alpha-catenin/vinculin-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| KRAB domain (Kruppel-associated box) | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
| Oxysterol-binding protein-like | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| LEM domain | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| TGS-like | 0 | DIRECT |
| FAD-binding/transporter-associated domain-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| FAS1 domain | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| 4-helical cytokines | 0 | DIRECT |
| Alpha-macroglobulin receptor domain | 0 | DIRECT |
| Di-copper centre-containing domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Phosphoglycerate mutase-like | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| ENTH/VHS domain | 0 | DIRECT |
| occludin/ELL-like | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| SRF-like | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| NAP-like | 0 | DIRECT |
| Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| Heme-dependent peroxidases | 0 | DIRECT |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
| Lamin A/C globular tail domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Second domain of FERM | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| BAG domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Ribosomal proteins L15p and L18e | 0 | DIRECT |
| Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Translation proteins | 0 | DIRECT |
| Plakin repeat | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Transcription factor STAT-4 N-domain | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Cyclophilin-like | 0 | DIRECT |
| PAH2 domain | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Cyclin-like | 0 | DIRECT |
| BEACH domain | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| GAT-like domain | 0 | DIRECT |
| Elongation factor TFIIS domain 2 | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| FAD-linked reductases, C-terminal domain | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| MAPEG domain-like | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| PRC-barrel domain | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| Annexin | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Ran binding protein zinc finger-like | 0 | DIRECT |
| C-terminal domain of adenylylcyclase associated protein | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Ribulose-phoshate binding barrel | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| AraD/HMP-PK domain-like | 0 | DIRECT |
| Enolase N-terminal domain-like | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Phosphoglucomutase, first 3 domains | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| FAD-dependent thiol oxidase | 0 | DIRECT |
| Histone-fold | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| eIF4e-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| Bcl-2 inhibitors of programmed cell death | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| MHC antigen-recognition domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | DIRECT |
| Glycolipid transfer protein, GLTP | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| RNA-binding domain, RBD | 0.007577 | INHERITED FROM: immune system || peripheral retina || egg || sensory system || spinal cord || genital system || intestine || hindbrain || urogenital system || endocrine system || liver and biliary system || gamete || musculoskeletal system || testis || eye || muscular system || forebrain || central nervous system || thymus |
| PH domain-like | 0.02824 | INHERITED FROM: brain |
| P-loop containing nucleoside triphosphate hydrolases | 0.03073 | INHERITED FROM: olfactory sensory neuron || genital system || urogenital system || testis |
| ARM repeat | 0.03547 | INHERITED FROM: egg || genital system || urogenital system || male genitalia || testis || central nervous system |
| Ubiquitin-like | 0.06055 | INHERITED FROM: central nervous system || brain |
| WD40 repeat-like | 0.1572 | INHERITED FROM: genital system || intestine || urogenital system || testis |
| HMG-box | 0.1891 | INHERITED FROM: sensory system || spinal cord || hindbrain || endocardium || endocardial tube || otic vesicle || splanchnocranium || midbrain-hindbrain boundary || forebrain || cardiovascular system || retinal layer |
| Tudor/PWWP/MBT | 0.1983 | INHERITED FROM: genital system || male genitalia || testis |
| Voltage-gated potassium channels | 0.2134 | INHERITED FROM: spinal cord || nerve || optic nerve || retinal inner plexiform layer || axon || neuron || retinal neural layer || optic disc || retinal ganglion cell layer || cephalic nerve |
| Ribonuclease H-like | 0.2173 | INHERITED FROM: genital system || urogenital system || testis |
| Nucleic acid-binding proteins | 0.2634 | INHERITED FROM: egg || genital system || urogenital system |
| Growth factor receptor domain | 0.2965 | INHERITED FROM: spinal cord || neuromere || urinary system || otic vesicle || cardiovascular system || heart |
| Plexin repeat | 0.3094 | INHERITED FROM: sensory system || otic placode || liver primordium || presumptive midbrain-hindbrain boundary |
| LDL receptor-like module | 0.3388 | INHERITED FROM: hindgut |
| Cadherin-like | 0.3695 | INHERITED FROM: nervous system || central nervous system |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.3697 | INHERITED FROM: immune system || endocrine system || skeletal muscle || thymus |
| NAD(P)-binding Rossmann-fold domains | 0.4194 | INHERITED FROM: intestine || anatomical cluster || viscus || alimentary system |
| FnI-like domain | 0.4195 | INHERITED FROM: neural tube || circulatory system || cardiovascular system || somite |
| SMAD/FHA domain | 0.4475 | INHERITED FROM: endocardium || heart |
| Thioredoxin-like | 0.455 | INHERITED FROM: skeletal tissue || bone element || early proximal tubule || bone tissue || dermal system || skeleton |
| Actin-like ATPase domain | 0.4908 | INHERITED FROM: jaw muscle || skeletal muscle || myocyte || pancreas || cranial muscle || heart || head somite |
| "Winged helix" DNA-binding domain | 0.493 | INHERITED FROM: sensory system || spinal cord || stomach || neural tube || musculoskeletal system || otic vesicle || hematological system || eye || hemangioblast || circulatory system || anterior ventral blood island || ventral blood island |
| Ras GEF | 0.4991 | INHERITED FROM: retinal inner plexiform layer || retinal outer plexiform layer |
| Tubulin nucleotide-binding domain-like | 0.4991 | INHERITED FROM: gustatory system || trigeminal nerve || neuron || glossopharyngeal nerve || facial nerve || epidermal cell || vagus nerve || epidermis || dermal system || spinal neuron || intersomitic neuron |
| Tubulin C-terminal domain-like | 0.5202 | INHERITED FROM: gustatory system || trigeminal nerve || neuron || glossopharyngeal nerve || facial nerve || epidermal cell || vagus nerve || epidermis || dermal system || spinal neuron || intersomitic neuron |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.5236 | INHERITED FROM: neural nucleus || basal forebrain || zona limitans intrathalamica || spinal cord || diencephalon || basal ganglion || pretectum || hindbrain || ventrolateral thalamic nucleus || thalamus || prosomere || neuromere || optic tectum || proximal tubule branch || ventral septum || midbrain || hypothalamus || liver diverticulum || prosomere 4 || striatum || hematological system || subpallium || anterior hypothalamus || septum || forebrain || lateral septum || cardiovascular system || medial septum || preoptic area || amygdala || lateral pallium || ventral pallium || central nucleus of the thalamus |
| Clavaminate synthase-like | 0.5674 | INHERITED FROM: early proximal tubule || late proximal tubule || late distal tubule |
| TIMP-like | 0.5907 | INHERITED FROM: foregut || cardiovascular system |
| SAM/Pointed domain | 0.6097 | INHERITED FROM: blood vessel || trunk vasculature || circulatory system |
| PLP-dependent transferases | 0.6173 | INHERITED FROM: intestine || anatomical cluster |
| EF-hand | 0.6246 | INHERITED FROM: left atrium || right atrium || cardiac ventricle || myocyte || cardiac atrium |
| Snake toxin-like | 0.6421 | INHERITED FROM: aorta || artery || dorsal aorta || trunk vasculature || hematological system || circulatory system || cardiovascular system || heart |
| Acyl-CoA dehydrogenase NM domain-like | 0.6421 | INHERITED FROM: muscle || skeletal muscle || muscular system |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.6421 | INHERITED FROM: muscle || skeletal muscle || muscular system |
| EGF/Laminin | 0.6656 | INHERITED FROM: spinal cord || heart || floor plate |
| SET domain | 0.689 | INHERITED FROM: hindbrain |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.7236 | INHERITED FROM: egg |
| Translation proteins SH3-like domain | 0.7252 | INHERITED FROM: immune system || skeletal tissue || bone element || skeletal element || muscle || endocrine system || skeletal system || musculoskeletal system || skeletal muscle || pancreas || muscular system || bone tissue || skeleton || thymus |
| Galactose-binding domain-like | 0.7274 | INHERITED FROM: optic nerve |
| Leukotriene A4 hydrolase N-terminal domain | 0.7554 | INHERITED FROM: pancreas |
| GroEL apical domain-like | 0.7554 | INHERITED FROM: immune system || anterior dorsal lateral plate region || muscle || endocrine system || skeletal muscle || skin || hematological system || muscular system || dermal system || thymus |
| Tropomyosin | 0.7583 | INHERITED FROM: left atrium || myocardium || outflow tract || myotome || myocyte || dermomyotome || cardiac atrium |
| GroEL equatorial domain-like | 0.7872 | INHERITED FROM: immune system || anterior dorsal lateral plate region || muscle || endocrine system || musculoskeletal system || skeletal muscle || skin || hematological system || muscular system || dermal system || thymus |
| GST C-terminal domain-like | 0.7956 | INHERITED FROM: dermal system |
| BPTI-like | 0.8191 | INHERITED FROM: skin || dermal system |
| lambda repressor-like DNA-binding domains | 0.8838 | INHERITED FROM: proximal tubule || spinal cord || early distal tubule || neuron || neural tube || pronephric tubule || presumptive midbrain-hindbrain boundary || late distal tubule || distal tubule |
| FYVE/PHD zinc finger | 0.9141 | INHERITED FROM: testis |
| Fibronectin type III | 0.9603 | INHERITED FROM: retinal inner nuclear layer || retinal neural layer || retinal ganglion cell layer |
| Intermediate filament protein, coiled coil region | 0.9935 | INHERITED FROM: neural nucleus || nerve || gustatory system || optic nerve || peripheral nervous system || retinal inner nuclear layer || retinal inner plexiform layer || spinal ganglion || medulla oblongata || neuron || retinal neural layer || nucleus reticularis inferior || vestibulocochlear nerve || ventricular zone || epidermis || retinal ganglion cell layer || midbrain tegmentum || dermal system || cephalic nerve || spinal neuron || ganglion || retinal ganglion cell |
| p53-like transcription factors | 0.9935 | INHERITED FROM: chondrocranium || sensory system || foregut || myocardium || cartilage tissue || skeletal subdivision || respiratory system || neuron || ceratohyal || facial nerve || primary heart field || lower jaw || lung bud || eye || cartilage element || branchial arch skeleton || cardiovascular system || heart || Meckel's cartilage || lung primordium |
| Cystine-knot cytokines | 1 | INHERITED FROM: mouth primordium || neural tube || appendicular skeleton || dorsal aorta || trunk vasculature || primary heart field || digit || circulatory system || hindlimb digit || cardiovascular system || heart || secondary heart field |
| Kazal-type serine protease inhibitors | 1 | INHERITED FROM: spinal cord || floor plate |
| gamma-Crystallin-like | 1 | INHERITED FROM: lens |
| TSP-1 type 1 repeat | 1 | INHERITED FROM: rectal diverticulum |
| Family A G protein-coupled receptor-like | 1 | INHERITED FROM: neural nucleus || basal forebrain || melanophore || diencephalon || basal ganglion || granule cell layer of the olfactory bulb || pigment cell || medial pallium || pallium || hypothalamus || striatum || anterior hypothalamus || septum || preoptic area || amygdala |
| Trypsin-like serine proteases | 1 | INHERITED FROM: pancreas |
| Metalloproteases ("zincins"), catalytic domain | 1 | INHERITED FROM: rectal diverticulum |
| Myosin rod fragments | 1 | INHERITED FROM: musculature of face |
| C-type lectin-like | 1 | INHERITED FROM: respiratory system |
| Homeodomain-like | 1 | INHERITED FROM: pallidum || neural nucleus || larval alimentary system || second pancreatic bud || proximal tubule || embryonic kidney || basal forebrain || sensory system || zona limitans intrathalamica || spinal cord || foregut || rostral presomitic mesoderm || nerve || cartilage tissue || dorsal thalamus || otic placode || early proximal tubule || mouth primordium || posterior hypothalamus || gut epithelium || caudal presomitic mesoderm || diencephalon || prethalamus || basal ganglion || skeletal subdivision || cranium || pronephric duct || pretectum || hindgut || respiratory system || optic stalk || infundibulum || peripheral nervous system || retinal inner nuclear layer || hindbrain || early distal tubule || stomach || small intestine || nervous system || medial ganglionic eminence || thalamus || midgut || neuron || neural tube || prosomere || neuromere || thyroid || profundus ganglion || pallium || lymphatic system || olfactory region || proximal tubule branch || anterior neural tube || right lymph heart || telencephalon || ventral septum || posterior neural tube || pronephric tubule || midbrain || hypothalamus || presomitic mesoderm || pronephric nephron || proliferative region || rhombomere || retinal pigmented epithelium || lower jaw || striatum || otic vesicle || subpallium || neurenteric canal || lung bud || eye || anterior hypothalamus || digit || cartilage element || enteric nervous system || presumptive midbrain-hindbrain boundary || midbrain-hindbrain boundary || late proximal tubule || eye primordium || circulatory system || neurocranium || septum || ventricular zone || posterior wall of neurenteric canal || optic tract || forebrain || retinal ganglion cell layer || lateral septum || olfactory bulb || hindlimb digit || lateral ganglionic eminence || cardiovascular system || medial septum || preoptic area || amygdala || somite || heart || lateral pallium || cephalic nerve || late distal tubule || pharynx || ventral pallium || optic vesicle || ganglion || distal tubule || chordoneural hinge || mesonephric duct || left lymph heart || large intestine |
| Immunoglobulin | 1 | INHERITED FROM: spleen || retinal inner nuclear layer |
| POZ domain | 1 | INHERITED FROM: axon || optic disc |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| UBC-like | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Cullin repeat-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| TAFH domain-like | 0 | Direct |
| NAD(P)-linked oxidoreductase | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| DNA clamp | 0 | Direct |
| NTF2-like | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Acyl-CoA binding protein | 0 | Direct |
| SCP-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Surp module (SWAP domain) | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| SNARE-like | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| Nitric oxide (NO) synthase oxygenase domain | 0 | Direct |
| FMN-linked oxidoreductases | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 0 | Direct |
| Dimeric alpha+beta barrel | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| Hook domain | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| DNase I-like | 0 | Direct |
| F-box domain | 0 | Direct |
| PAZ domain | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| TNF receptor-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| LigT-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit VIIa | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| PRTase-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Nucleotide cyclase | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| TRAF domain-like | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Nop domain | 0 | Direct |
| Calcium-dependent phosphotriesterase | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Sema domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| Globin-like | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Eferin C-derminal domain-like | 0 | Direct |
| IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
| L27 domain | 0 | Direct |
| Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Chaperone J-domain | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Flavoproteins | 0 | Direct |
| L30e-like | 0 | Direct |
| Synuclein | 0 | Direct |
| Class II aaRS and biotin synthetases | 0 | Direct |
| Carbonic anhydrase | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| Orange domain-like | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| P-domain of calnexin/calreticulin | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Sialidases | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| FF domain | 0 | Direct |
| Mss4-like | 0 | Direct |
| Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Enolase C-terminal domain-like | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| ALDH-like | 0 | Direct |
| Ammonium transporter | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Mannose 6-phosphate receptor domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Nucleoplasmin-like core domain | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| SRCR-like | 0 | Direct |
| SAP domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| SIS domain | 0 | Direct |
| Cryptochrome/photolyase, N-terminal domain | 0 | Direct |
| Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| RGC domain-like | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Connexin43 | 0 | Direct |
| Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| STAT | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| Transcription factor IIA (TFIIA), beta-barrel domain | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Transducin (heterotrimeric G protein), gamma chain | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| LysM domain | 0 | Direct |
| GYF domain | 0 | Direct |
| MIT domain | 0 | Direct |
| Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| ATP-dependent DNA ligase DNA-binding domain | 0 | Direct |
| RUN domain-like | 0 | Direct |
| Band 7/SPFH domain | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| eIF1-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| GroES-like | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| GFP-like | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| DLC | 0 | Direct |
| WGR domain-like | 0 | Direct |
| alpha-catenin/vinculin-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| KRAB domain (Kruppel-associated box) | 0 | Direct |
| Trefoil | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| ACT-like | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
| Oxysterol-binding protein-like | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| LEM domain | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| TGS-like | 0 | Direct |
| FAD-binding/transporter-associated domain-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| PapD-like | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| ClpS-like | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| FAS1 domain | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| 4-helical cytokines | 0 | Direct |
| Alpha-macroglobulin receptor domain | 0 | Direct |
| Di-copper centre-containing domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Translational machinery components | 0 | Direct |
| BSD domain-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Phosphoglycerate mutase-like | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| DUSP-like | 0 | Direct |
| ENTH/VHS domain | 0 | Direct |
| occludin/ELL-like | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| Stathmin | 0 | Direct |
| SRF-like | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| NAP-like | 0 | Direct |
| Cation efflux protein cytoplasmic domain-like | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| Heme-dependent peroxidases | 0 | Direct |
| Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
| Lamin A/C globular tail domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Second domain of FERM | 0 | Direct |
| PX domain | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| BAG domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Ribosomal proteins L15p and L18e | 0 | Direct |
| Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Translation proteins | 0 | Direct |
| Plakin repeat | 0 | Direct |
| KA1-like | 0 | Direct |
| Bromodomain | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Transcription factor IIA (TFIIA), alpha-helical domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| Proteasome activator | 0 | Direct |
| GLA-domain | 0 | Direct |
| Transcription factor STAT-4 N-domain | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Cyclophilin-like | 0 | Direct |
| PAH2 domain | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Cyclin-like | 0 | Direct |
| BEACH domain | 0 | Direct |
| Tim10-like | 0 | Direct |
| GAT-like domain | 0 | Direct |
| Elongation factor TFIIS domain 2 | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| FAD-linked reductases, C-terminal domain | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| MAPEG domain-like | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
| HCP-like | 0 | Direct |
| PRC-barrel domain | 0 | Direct |
| Pentein | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| Annexin | 0 | Direct |
| Caspase-like | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Ran binding protein zinc finger-like | 0 | Direct |
| C-terminal domain of adenylylcyclase associated protein | 0 | Direct |
| HRDC-like | 0 | Direct |
| Ribulose-phoshate binding barrel | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| AraD/HMP-PK domain-like | 0 | Direct |
| Enolase N-terminal domain-like | 0 | Direct |
| ACP-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Insulin-like | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Nudix | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Phosphoglucomutase, first 3 domains | 0 | Direct |
| ARID-like | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| FAD-dependent thiol oxidase | 0 | Direct |
| Histone-fold | 0 | Direct |
| Prefoldin | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| eIF4e-like | 0 | Direct |
| Aldolase | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Notch domain | 0 | Direct |
| Cytokine | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| Bcl-2 inhibitors of programmed cell death | 0 | Direct |
| YWTD domain | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| MHC antigen-recognition domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Delta-sleep-inducing peptide immunoreactive peptide | 0 | Direct |
| Glycolipid transfer protein, GLTP | 0 | Direct |
| MIR domain | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| RNA-binding domain, RBD | 0.007577 | Inherited |
| PH domain-like | 0.02824 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.03073 | Inherited |
| ARM repeat | 0.03547 | Inherited |
| Ubiquitin-like | 0.06055 | Inherited |
| WD40 repeat-like | 0.1572 | Inherited |
| HMG-box | 0.1891 | Inherited |
| Tudor/PWWP/MBT | 0.1983 | Inherited |
| Voltage-gated potassium channels | 0.2134 | Inherited |
| Ribonuclease H-like | 0.2173 | Inherited |
| Nucleic acid-binding proteins | 0.2634 | Inherited |
| Growth factor receptor domain | 0.2965 | Inherited |
| Plexin repeat | 0.3094 | Inherited |
| LDL receptor-like module | 0.3388 | Inherited |
| Cadherin-like | 0.3695 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0.3697 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.4194 | Inherited |
| FnI-like domain | 0.4195 | Inherited |
| SMAD/FHA domain | 0.4475 | Inherited |
| Thioredoxin-like | 0.455 | Inherited |
| Actin-like ATPase domain | 0.4908 | Inherited |
| "Winged helix" DNA-binding domain | 0.493 | Inherited |
| Ras GEF | 0.4991 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.4991 | Inherited |
| Tubulin C-terminal domain-like | 0.5202 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.5236 | Inherited |
| Clavaminate synthase-like | 0.5674 | Inherited |
| TIMP-like | 0.5907 | Inherited |
| SAM/Pointed domain | 0.6097 | Inherited |
| PLP-dependent transferases | 0.6173 | Inherited |
| EF-hand | 0.6246 | Inherited |
| Snake toxin-like | 0.6421 | Inherited |
| Acyl-CoA dehydrogenase NM domain-like | 0.6421 | Inherited |
| Acyl-CoA dehydrogenase C-terminal domain-like | 0.6421 | Inherited |
| EGF/Laminin | 0.6656 | Inherited |
| SET domain | 0.689 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 0.7236 | Inherited |
| Translation proteins SH3-like domain | 0.7252 | Inherited |
| Galactose-binding domain-like | 0.7274 | Inherited |
| Leukotriene A4 hydrolase N-terminal domain | 0.7554 | Inherited |
| GroEL apical domain-like | 0.7554 | Inherited |
| Tropomyosin | 0.7583 | Inherited |
| GroEL equatorial domain-like | 0.7872 | Inherited |
| GST C-terminal domain-like | 0.7956 | Inherited |
| BPTI-like | 0.8191 | Inherited |
| lambda repressor-like DNA-binding domains | 0.8838 | Inherited |
| FYVE/PHD zinc finger | 0.9141 | Inherited |
| Fibronectin type III | 0.9603 | Inherited |
| Intermediate filament protein, coiled coil region | 0.9935 | Inherited |
| p53-like transcription factors | 0.9935 | Inherited |
| Cystine-knot cytokines | 1 | Inherited |
| Kazal-type serine protease inhibitors | 1 | Inherited |
| gamma-Crystallin-like | 1 | Inherited |
| TSP-1 type 1 repeat | 1 | Inherited |
| Family A G protein-coupled receptor-like | 1 | Inherited |
| Trypsin-like serine proteases | 1 | Inherited |
| Metalloproteases ("zincins"), catalytic domain | 1 | Inherited |
| Myosin rod fragments | 1 | Inherited |
| C-type lectin-like | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| POZ domain | 1 | Inherited |
(show details)
Supra-domains annotated to this XA term (Not in SPXA)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49854,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | DIRECT |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | DIRECT |
56487,50494
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | DIRECT |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | DIRECT |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | DIRECT |
57196,100895
57196 - EGF/Laminin
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | DIRECT |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | DIRECT |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | DIRECT |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | DIRECT |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
46966,47473
46966 - Spectrin repeat
47473 - EF-hand | 0 | DIRECT |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | DIRECT |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | DIRECT |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
57196,56436
57196 - EGF/Laminin
56436 - C-type lectin-like | 0 | DIRECT |
49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | DIRECT |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
57535,57196
57535 - Complement control module/SCR domain
57196 - EGF/Laminin | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
81324,81324
81324 - Voltage-gated potassium channels
81324 - Voltage-gated potassium channels | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56487,56487
56487 - SRCR-like
56487 - SRCR-like | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | DIRECT |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0 | DIRECT |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
52425,48173
52425 - Cryptochrome/photolyase, N-terminal domain
48173 - Cryptochrome/photolyase FAD-binding domain | 0 | DIRECT |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | DIRECT |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | DIRECT |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
50729,48350
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
48065,103657
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like | 0 | DIRECT |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | DIRECT |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0 | DIRECT |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | DIRECT |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | DIRECT |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | DIRECT |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0 | DIRECT |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | DIRECT |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | DIRECT |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | DIRECT |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | DIRECT |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | DIRECT |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | DIRECT |
55550,158235
55550 - SH2 domain
158235 - SOCS box-like | 0 | DIRECT |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | DIRECT |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47473,57850
47473 - EF-hand
57850 - RING/U-box | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
64268,50044
64268 - PX domain
50044 - SH3-domain | 0 | DIRECT |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | DIRECT |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
50044,50156
50044 - SH3-domain
50156 - PDZ domain-like | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | DIRECT |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | DIRECT |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | DIRECT |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
47661,58038
47661 - t-snare proteins
58038 - SNARE fusion complex | 0 | DIRECT |
56512,52218
56512 - Nitric oxide (NO) synthase oxygenase domain
52218 - Flavoproteins | 0 | DIRECT |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57567,57603
57567 - Serine protease inhibitors
57603 - FnI-like domain | 0 | DIRECT |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | DIRECT |
50156,50729
50156 - PDZ domain-like
50729 - PH domain-like | 0 | DIRECT |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | DIRECT |
51045,50156
51045 - WW domain
50156 - PDZ domain-like | 0 | DIRECT |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | DIRECT |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54160,57850
54160 - Chromo domain-like
57850 - RING/U-box | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | DIRECT |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
46785,54928
46785 - "Winged helix" DNA-binding domain
54928 - RNA-binding domain, RBD | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
103657,50044
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | DIRECT |
57184,100895
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | DIRECT |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | DIRECT |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | DIRECT |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | DIRECT |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | DIRECT |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | DIRECT |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | DIRECT |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | DIRECT |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | DIRECT |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | DIRECT |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
48726,56436
48726 - Immunoglobulin
56436 - C-type lectin-like | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | DIRECT |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | DIRECT |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | DIRECT |
117281,50965
117281 - Kelch motif
50965 - Galactose oxidase, central domain | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | DIRECT |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07311 | INHERITED FROM: testis |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.1725 | INHERITED FROM: immune system || visual system || egg || intestine || endocrine system || liver and biliary system || gamete || musculoskeletal system || skeletal muscle || muscular system || viscus || alimentary system || central nervous system || thymus |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.1725 | INHERITED FROM: neural nucleus || anterior thalamic nucleus || basal forebrain || sensory system || zona limitans intrathalamica || nerve || anterior dorsal lateral plate region || trigeminal ganglion || basal ganglion || cranium || pretectum || hindbrain || ventrolateral thalamic nucleus || thalamus || prosomere || medial amygdala || neuromere || skeletal system || pallium || optic tectum || dorsal aorta || ventral septum || hypothalamus || anatomical cluster || prosomere 4 || striatum || otic vesicle || hematological system || subpallium || anterior hypothalamus || septum || bed nucleus of the stria terminalis || forebrain || lateral septum || ventral blood island || cardiovascular system || medial septum || preoptic area || amygdala || heart || lateral pallium || cephalic nerve || ventral pallium || central nucleus of the thalamus |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.2478 | INHERITED FROM: muscle || jaw muscle || skeletal muscle || myocyte || pancreas || cranial muscle || heart || head somite |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.3094 | INHERITED FROM: genital system || testis |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.3932 | INHERITED FROM: nervous system || central nervous system |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.4017 | INHERITED FROM: spinal cord || hypothalamus |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.5202 | INHERITED FROM: gustatory system || trigeminal nerve || neuron || glossopharyngeal nerve || facial nerve || epidermal cell || vagus nerve || epidermis || dermal system || spinal neuron || intersomitic neuron |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0.5674 | INHERITED FROM: pancreas |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.5674 | INHERITED FROM: retinal inner nuclear layer |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.5737 | INHERITED FROM: head vasculature || cardiovascular system || heart |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.6421 | INHERITED FROM: muscle || skeletal muscle || muscular system |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.6512 | INHERITED FROM: female genitalia || ovary |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0.6987 | INHERITED FROM: spinal cord || retinal inner nuclear layer || retinal neural layer || retinal ganglion cell layer |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0.7554 | INHERITED FROM: pancreas |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0.8526 | INHERITED FROM: blood vessel || circulatory system || cardiovascular system |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.8762 | INHERITED FROM: spinal cord || hindbrain || otic region |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.9046 | INHERITED FROM: spinal cord || retinal inner nuclear layer || retinal neural layer || retinal ganglion cell layer |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.9394 | INHERITED FROM: skin || dermal system |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0.953 | INHERITED FROM: neuron || neural tube || pronephric tubule || presumptive midbrain-hindbrain boundary || retinal ganglion cell layer |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 1 | INHERITED FROM: rectal diverticulum |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49854,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | Direct |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
82109,82109
82109 - MIR domain
82109 - MIR domain | 0 | Direct |
56487,50494
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | Direct |
50998,50978
50998 - Quinoprotein alcohol dehydrogenase-like
50978 - WD40 repeat-like | 0 | Direct |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | Direct |
57184,49899
57184 - Growth factor receptor domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57889,48350
57889 - Cysteine-rich domain
48350 - GTPase activation domain, GAP | 0 | Direct |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
54534,47473
54534 - FKBP-like
47473 - EF-hand | 0 | Direct |
57196,100895
57196 - EGF/Laminin
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | Direct |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
110324,50249
110324 - Ribosomal L27 protein-like
50249 - Nucleic acid-binding proteins | 0 | Direct |
117018,56091
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
54511,57184
54511 - GFP-like
57184 - Growth factor receptor domain | 0 | Direct |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | Direct |
49313,49899
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
55550,50729
55550 - SH2 domain
50729 - PH domain-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
57586,57586
57586 - TNF receptor-like
57586 - TNF receptor-like | 0 | Direct |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | Direct |
46966,47473
46966 - Spectrin repeat
47473 - EF-hand | 0 | Direct |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | Direct |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | Direct |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
53300,69318
53300 - vWA-like
69318 - Integrin alpha N-terminal domain | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57535,49854
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
48464,89009
48464 - ENTH/VHS domain
89009 - GAT-like domain | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | Direct |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0 | Direct |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
57196,56436
57196 - EGF/Laminin
56436 - C-type lectin-like | 0 | Direct |
49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | Direct |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
57535,57196
57535 - Complement control module/SCR domain
57196 - EGF/Laminin | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
81324,81324
81324 - Voltage-gated potassium channels
81324 - Voltage-gated potassium channels | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56487,56487
56487 - SRCR-like
56487 - SRCR-like | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
64593,74853
64593 - Intermediate filament protein, coiled coil region
74853 - Lamin A/C globular tail domain | 0 | Direct |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
103575,48726
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0 | Direct |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
52425,48173
52425 - Cryptochrome/photolyase, N-terminal domain
48173 - Cryptochrome/photolyase FAD-binding domain | 0 | Direct |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
64356,49447
64356 - SNARE-like
49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | Direct |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | Direct |
56968,48431
56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
50729,48350
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
48065,103657
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like | 0 | Direct |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | Direct |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0 | Direct |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0 | Direct |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | Direct |
48092,47655
48092 - Transcription factor STAT-4 N-domain
47655 - STAT | 0 | Direct |
81296,48239
81296 - E set domains
48239 - Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0 | Direct |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
82895,57424
82895 - TSP-1 type 1 repeat
57424 - LDL receptor-like module | 0 | Direct |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
49265,56496
49265 - Fibronectin type III
56496 - Fibrinogen C-terminal domain-like | 0 | Direct |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | Direct |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
49417,55550
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
49899,63887
49899 - Concanavalin A-like lectins/glucanases
63887 - P-domain of calnexin/calreticulin | 0 | Direct |
57603,57603
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | Direct |
57863,48403
57863 - ArfGap/RecO-like zinc finger
48403 - Ankyrin repeat | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
63501,50242
63501 - Frizzled cysteine-rich domain
50242 - TIMP-like | 0 | Direct |
55550,158235
55550 - SH2 domain
158235 - SOCS box-like | 0 | Direct |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
50729,81837
50729 - PH domain-like
81837 - BEACH domain | 0 | Direct |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47473,57850
47473 - EF-hand
57850 - RING/U-box | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
64268,50044
64268 - PX domain
50044 - SH3-domain | 0 | Direct |
48403,50044
48403 - Ankyrin repeat
50044 - SH3-domain | 0 | Direct |
47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
81383,50978
81383 - F-box domain
50978 - WD40 repeat-like | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
50044,50156
50044 - SH3-domain
50156 - PDZ domain-like | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
54452,48726
54452 - MHC antigen-recognition domain
48726 - Immunoglobulin | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,49265
53300 - vWA-like
49265 - Fibronectin type III | 0 | Direct |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
54534,54534
54534 - FKBP-like
54534 - FKBP-like | 0 | Direct |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | Direct |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
47661,58038
47661 - t-snare proteins
58038 - SNARE fusion complex | 0 | Direct |
56512,52218
56512 - Nitric oxide (NO) synthase oxygenase domain
52218 - Flavoproteins | 0 | Direct |
52087,101576
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
57184,63825
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57567,57603
57567 - Serine protease inhibitors
57603 - FnI-like domain | 0 | Direct |
81271,55186
81271 - TGS-like
55186 - ThrRS/AlaRS common domain | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
46942,57783
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon | 0 | Direct |
50156,50729
50156 - PDZ domain-like
50729 - PH domain-like | 0 | Direct |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
81324,53850
81324 - Voltage-gated potassium channels
53850 - Periplasmic binding protein-like II | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0 | Direct |
51045,50156
51045 - WW domain
50156 - PDZ domain-like | 0 | Direct |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | Direct |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54160,57850
54160 - Chromo domain-like
57850 - RING/U-box | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
47655,49417
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | Direct |
117281,117281
117281 - Kelch motif
117281 - Kelch motif | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
46785,54928
46785 - "Winged helix" DNA-binding domain
54928 - RNA-binding domain, RBD | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
82109,100909
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
103657,50044
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | Direct |
57184,100895
57184 - Growth factor receptor domain
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
47576,48065
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
64268,103657
64268 - PX domain
103657 - BAR/IMD domain-like | 0 | Direct |
51735,48179
51735 - NAD(P)-binding Rossmann-fold domains
48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
48350,50729
48350 - GTPase activation domain, GAP
50729 - PH domain-like | 0 | Direct |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | Direct |
56112,55073
56112 - Protein kinase-like (PK-like)
55073 - Nucleotide cyclase | 0 | Direct |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | Direct |
52540,48340
52540 - P-loop containing nucleoside triphosphate hydrolases
48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0 | Direct |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | Direct |
50494,50494
50494 - Trypsin-like serine proteases
50494 - Trypsin-like serine proteases | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
52540,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain | 0 | Direct |
82153,82153
82153 - FAS1 domain
82153 - FAS1 domain | 0 | Direct |
57863,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like | 0 | Direct |
50729,49562
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | Direct |
55753,82754
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
48726,56436
48726 - Immunoglobulin
56436 - C-type lectin-like | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
57903,51197
57903 - FYVE/PHD zinc finger
51197 - Clavaminate synthase-like | 0 | Direct |
57196,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain | 0 | Direct |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50729,57863
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
54236,50729
54236 - Ubiquitin-like
50729 - PH domain-like | 0 | Direct |
117281,50965
117281 - Kelch motif
50965 - Galactose oxidase, central domain | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | Direct |
161111,160240
161111 - Cation efflux protein transmembrane domain-like
160240 - Cation efflux protein cytoplasmic domain-like | 0 | Direct |
103637,103637
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07311 | Inherited |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.1725 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.1725 | Inherited |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.2478 | Inherited |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.3094 | Inherited |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.3932 | Inherited |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0.4017 | Inherited |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0.5202 | Inherited |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0.5674 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.5674 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.5737 | Inherited |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0.6421 | Inherited |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.6512 | Inherited |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0.6987 | Inherited |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0.7554 | Inherited |
53300,53300
53300 - vWA-like
53300 - vWA-like | 0.8526 | Inherited |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.8762 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.9046 | Inherited |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0.9394 | Inherited |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0.953 | Inherited |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 1 | Inherited |
(show details)
Supra-domains annotated to this XA term (Not in SPXA)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
90257,90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
57196,57196,49899
57196 - EGF/Laminin
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | DIRECT |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
63748,63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50044,55550,50044
50044 - SH3-domain
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | DIRECT |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | DIRECT |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | DIRECT |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49785,49785,49899
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | DIRECT |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
48726,56436,56436
48726 - Immunoglobulin
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | DIRECT |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
90229,90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
54160,57850,57845
54160 - Chromo domain-like
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | DIRECT |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
48065,103657,50044
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | DIRECT |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
49562,49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | DIRECT |
46966,46966,47473
46966 - Spectrin repeat
46966 - Spectrin repeat
47473 - EF-hand | 0 | DIRECT |
57196,49899,57196
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54511,57184,57184
54511 - GFP-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | DIRECT |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5422 | INHERITED FROM: skeletal system || cardiovascular system || heart |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.6701 | INHERITED FROM: female genitalia || neuron || ovary |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.7393 | INHERITED FROM: floor plate |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0.8191 | INHERITED FROM: urinary system || kidney || tail somite || chordoneural hinge || trunk somite |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.8526 | INHERITED FROM: optic vesicle |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57184,57184,57196
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49899,57196,49899
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
90257,90257,90257
90257 - Myosin rod fragments
90257 - Myosin rod fragments
90257 - Myosin rod fragments | 0 | Direct |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
47655,49417,55550
47655 - STAT
49417 - p53-like transcription factors
55550 - SH2 domain | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
57196,57196,49899
57196 - EGF/Laminin
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
103657,50729,48350
103657 - BAR/IMD domain-like
50729 - PH domain-like
48350 - GTPase activation domain, GAP | 0 | Direct |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
47459,55785,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
56436,56436,56436
56436 - C-type lectin-like
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
57184,57196,57184
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
64268,50044,50044
64268 - PX domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
49899,49899,57196
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
63748,63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50044,55550,50044
50044 - SH3-domain
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
103637,103637,103637
103637 - CCHHC domain
103637 - CCHHC domain
103637 - CCHHC domain | 0 | Direct |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
57184,57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
53300,69318,69179
53300 - vWA-like
69318 - Integrin alpha N-terminal domain
69179 - Integrin domains | 0 | Direct |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
50129,51735,50129
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 0 | Direct |
57196,57535,57535
57196 - EGF/Laminin
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
49785,49785,49899
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,57196,69687
57196 - EGF/Laminin
57196 - EGF/Laminin
69687 - Integrin beta tail domain | 0 | Direct |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
117018,56091,50249
117018 - ATP-dependent DNA ligase DNA-binding domain
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
57535,49854,57535
57535 - Complement control module/SCR domain
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
46689,46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | Direct |
50729,49562,48350
50729 - PH domain-like
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
48726,56436,56436
48726 - Immunoglobulin
56436 - C-type lectin-like
56436 - C-type lectin-like | 0 | Direct |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
90229,90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | Direct |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
101912,103575,48726
101912 - Sema domain
103575 - Plexin repeat
48726 - Immunoglobulin | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
54160,57850,57845
54160 - Chromo domain-like
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | Direct |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
48092,47655,49417
48092 - Transcription factor STAT-4 N-domain
47655 - STAT
49417 - p53-like transcription factors | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
52833,52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
48065,103657,50044
48065 - DBL homology domain (DH-domain)
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | Direct |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
52540,51045,51045
52540 - P-loop containing nucleoside triphosphate hydrolases
51045 - WW domain
51045 - WW domain | 0 | Direct |
49313,49313,49899
49313 - Cadherin-like
49313 - Cadherin-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
46938,52087,101576
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
101576 - Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
57863,50729,50729
57863 - ArfGap/RecO-like zinc finger
50729 - PH domain-like
50729 - PH domain-like | 0 | Direct |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50044,50044,50044
50044 - SH3-domain
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
82109,82109,100909
82109 - MIR domain
82109 - MIR domain
100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
47576,48065,50729
47576 - Calponin-homology domain, CH-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
49562,49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | Direct |
46966,46966,47473
46966 - Spectrin repeat
46966 - Spectrin repeat
47473 - EF-hand | 0 | Direct |
57196,49899,57196
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54511,57184,57184
54511 - GFP-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
103657,50729,57863
103657 - BAR/IMD domain-like
50729 - PH domain-like
57863 - ArfGap/RecO-like zinc finger | 0 | Direct |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57603,57603,57603
57603 - FnI-like domain
57603 - FnI-like domain
57603 - FnI-like domain | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.5422 | Inherited |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.6701 | Inherited |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.7393 | Inherited |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0.8191 | Inherited |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.8526 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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