Xenopus ANatomical entity (XAN): anatomical cluster

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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)

Shortest distance to current term (+ for parents, - for children) XA term [XA ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)

+ + + 3: Xenopus anatomical entity [XAO:0000000] <9>

+ + 2: anatomical structure [XAO:0003000] <11> (577|733) (577|400|163)

+ + 2: whole organism [XAO:0003004] <12> (461|598) (465|335|145)

+ 1: anatomical group [XAO:0003001] <2> (414|530) (418|309|134)

0: anatomical cluster [XAO:0003160] <43> (92|141) (95|75|38)

- 1: neural nucleus [XAO:0004609] <34> (4|4) (4|1|0)

- 1: skeletal subdivision [XAO:0004289] <16> (3|2) (3|0|0)

- 1: cranium [XAO:0003075] <14> (5|9) (5|3|1)

- 1: inner ear [XAO:0000192] <13> (1|1) (1|1|1)

- 1: viscus [XAO:0003034] <9> (63|96) (66|45|21)

- 1: amygdala [XAO:0004531] <4> (3|3) (3|1|0)

- 1: septum [XAO:0004585] <4> (3|3) (3|1|0)

- 1: basal ganglion [XAO:0004540] <3> (3|2) (3|1|0)

- 1: digit [XAO:0003032] <3> (2|1) (2|0|0)

- 1: pallidum [XAO:0004578] <3> (1|1) (1|0|0)

- 1: skeleton [XAO:0004053] <3> (13|9) (13|4|2)

- 1: trunk musculature [XAO:0003230] <3> (3|5) (3|2|1)

- 1: proliferative region [XAO:0004122] <2> (3|2) (4|1|0)

- 1: striatum [XAO:0004587] <2> (2|2) (3|1|0)

- 1: craniofacial region [XAO:0004024] <1> (0|0) (0|0|0)

- 1: ethmoid region [XAO:0005192] <1> (0|0) (0|0|0)

- 1: lower jaw [XAO:0003084] <1> (2|2) (2|0|0)

- 1: middle ear [XAO:0000191] <1> (0|0) (0|0|0)

- 1: otic region [XAO:0003175] <1> (0|0) (0|1|0)

- 1: anterior commissure [XAO:0004533] (0|0) (0|0|0)

- 1: central canal [XAO:0004543] (0|0) (0|0|0)

- 1: dorsal funiculus [XAO:0004580] (0|0) (0|0|0)

- 1: dorsal pallidum [XAO:0004547] (0|0) (0|0|0)

- 1: dorsal septum [XAO:0004549] (0|0) (0|0|0)

- 1: joint [XAO:0000171] (0|0) (0|0|0)

- 1: lateral forebrain bundle [XAO:0004559] (0|0) (0|0|0)

- 1: lateral funiculus [XAO:0004560] (0|0) (0|0|0)

- 1: lateral septum [XAO:0004564] (2|1) (2|1|0)

- 1: medial septum [XAO:0004571] (2|1) (2|1|0)

- 1: neurocranium [XAO:0003170] (1|1) (1|0|0)

- 1: occipital region [XAO:0003173] (0|0) (0|0|0)

- 1: olfactory region [XAO:0003172] (2|3) (2|0|0)

- 1: orbital region [XAO:0003171] (0|0) (0|0|0)

- 1: oropharynx [XAO:0004048] (0|0) (0|0|0)

- 1: posterior commissure [XAO:0004579] (0|0) (0|0|0)

- 1: solitary tract [XAO:0004586] (0|0) (0|0|0)

- 1: sphenoid region [XAO:0003174] (0|0) (0|0|0)

- 1: stria terminalis [XAO:0005057] (0|0) (0|0|0)

- 1: suspensorium [XAO:0003086] (0|0) (0|0|0)

- 1: upper jaw [XAO:0003087] (0|0) (0|0|0)

- 1: ventral funiculus [XAO:0004535] (0|0) (0|0|0)

- 1: ventral pallidum [XAO:0004593] (0|0) (0|0|0)

- 1: ventral septum [XAO:0005055] (2|2) (2|1|0)

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Superfamily

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SCOP term	FDR (all)	Annotation (direct or inherited)
alpha-ketoacid dehydrogenase kinase, N-terminal domain	0	Direct
SCP-like	0	Direct
RmlC-like cupins	0	Direct
PAH2 domain	0	Direct
Succinyl-CoA synthetase domains	0	Direct
DnaJ/Hsp40 cysteine-rich domain	0	Direct
Thiolase-like	0	Direct
Mannose 6-phosphate receptor domain	0	Direct
Mitochondrial cytochrome c oxidase subunit VIIa	0	Direct
Troponin coil-coiled subunits	0	Direct
F1F0 ATP synthase subunit C	0	Direct
4Fe-4S ferredoxins	0	Direct
Aminomethyltransferase beta-barrel domain	0	Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions	0	Direct
TB module/8-cys domain	0	Direct
Moesin tail domain	0	Direct
Fibrinogen coiled-coil and central regions	0	Direct
Bacterial exopeptidase dimerisation domain	0	Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	0	Direct
NAP-like	0	Direct
Isocitrate/Isopropylmalate dehydrogenase-like	0	Direct
Amidase signature (AS) enzymes	0	Direct
Mib/herc2 domain-like	0	Direct
MAPEG domain-like	0	Direct
N-acetylmuramoyl-L-alanine amidase-like	0	Direct
CoA-dependent acyltransferases	0	Direct
Guanido kinase N-terminal domain	0	Direct
Subunits of heterodimeric actin filament capping protein Capz	0	Direct
ACP-like	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	0	Direct
FAS1 domain	0	Direct
IP3 receptor type 1 binding core, domain 2	0	Direct
PLP-binding barrel	0	Direct
Apolipoprotein A-I	0	Direct
Surp module (SWAP domain)	0	Direct
Glutamine synthetase/guanido kinase	0	Direct
MHC antigen-recognition domain	0	Direct
TGS-like	0	Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain	0	Direct
AraD/HMP-PK domain-like	0	Direct
HRDC-like	0	Direct
TK C-terminal domain-like	0	Direct
Plakin repeat	0	Direct
BSD domain-like	0	Direct
Hedgehog/DD-peptidase	0	Direct
Alanine racemase C-terminal domain-like	0	Direct
ADP-ribosylglycohydrolase	0	Direct
Nop domain	0	Direct
Lipovitellin-phosvitin complex, superhelical domain	0	Direct
Cullin repeat-like	0	Direct
SRF-like	0	Direct
Delta-sleep-inducing peptide immunoreactive peptide	0	Direct
eIF1-like	0	Direct
NAD(P)-binding Rossmann-fold domains	0.00007918	Direct
PLP-dependent transferases	0.0002193	Direct
UBC-like	0.002508	Inherited
RNA-binding domain, RBD	0.006032	Inherited
ALDH-like	0.01712	Inherited
Thiamin diphosphate-binding fold (THDP-binding)	0.02431	Inherited
Actin-like ATPase domain	0.02579	Inherited
Annexin	0.03633	Inherited
Translation proteins SH3-like domain	0.08602	Inherited
SMAD MH1 domain	0.1149	Inherited
Trypsin-like serine proteases	0.1195	Inherited
Leukotriene A4 hydrolase N-terminal domain	0.1213	Inherited
Thioredoxin-like	0.1396	Inherited
WD40 repeat-like	0.156	Inherited
Zn-binding ribosomal proteins	0.1643	Inherited
Translational machinery components	0.1643	Inherited
Glucocorticoid receptor-like (DNA-binding domain)	0.1895	Inherited
LDH C-terminal domain-like	0.2324	Inherited
SMAD/FHA domain	0.2866	Inherited
Actin depolymerizing proteins	0.3011	Inherited
"Winged helix" DNA-binding domain	0.31	Inherited
GINS helical bundle-like	0.3258	Inherited
Snake toxin-like	0.4654	Inherited
HMG-box	0.4988	Inherited
p53-like transcription factors	0.5112	Inherited
Intermediate filament protein, coiled coil region	0.5112	Inherited
Spectrin repeat	0.5499	Inherited
Tropomyosin	0.5528	Inherited
EF-hand	0.6907	Inherited
EGF/Laminin	0.7319	Inherited
PYP-like sensor domain (PAS domain)	0.7865	Inherited
HLH, helix-loop-helix DNA-binding domain	0.8869	Inherited
Frizzled cysteine-rich domain	0.9	Inherited
Growth factor receptor domain	0.9181	Inherited
Homeodomain-like	1	Inherited
Cystine-knot cytokines	1	Inherited
Family A G protein-coupled receptor-like	1	Inherited
Cytokine	1	Inherited

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Family

(show details)

SCOP term	FDR (all)	Annotation (direct or inherited)
Thiolase-related	0	Direct
Hedgehog (development protein), N-terminal signaling domain	0	Direct
Ferritin	0	Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain	0	Direct
IP3 receptor type 1 binding core, domain 2	0	Direct
Pumilio repeat	0	Direct
Neurolysin-like	0	Direct
eIF1-like	0	Direct
UDP-glucose pyrophosphorylase	0	Direct
Fibronectin type II module	0	Direct
Mib/herc2 domain	0	Direct
Cofactor-dependent phosphoglycerate mutase	0	Direct
MHC antigen-recognition domain	0	Direct
ADP-ribosylglycohydrolase	0	Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)	0	Direct
FAS1 domain	0	Direct
Arginase-like amidino hydrolases	0	Direct
Protein-L-isoaspartyl O-methyltransferase	0	Direct
RuBisCo LSMT catalytic domain	0	Direct
HCDH C-domain-like	0	Direct
Glucose 6-phosphate dehydrogenase-like	0	Direct
Mannose 6-phosphate receptor domain	0	Direct
Crotonase-like	0	Direct
HAT/Suf repeat	0	Direct
RUNT domain	0	Direct
gamma-adaptin C-terminal appendage domain-like	0	Direct
Guanido kinase catalytic domain	0	Direct
Group II chaperonin (CCT, TRIC), intermediate domain	0	Direct
F1F0 ATP synthase subunit C	0	Direct
UDPGT-like	0	Direct
Plakin repeat	0	Direct
Bacterial exopeptidase dimerisation domain	0	Direct
NIPSNAP	0	Direct
DNA ligase	0	Direct
Phenylalanine metabolism regulatory domain	0	Direct
Fibronectin type I module	0	Direct
Netrin-like domain (NTR/C345C module)	0	Direct
Alpha-adaptin ear subdomain-like	0	Direct
SRF-like	0	Direct
SIAH, seven in absentia homolog	0	Direct
GABARAP-like	0	Direct
C1 set domains (antibody constant domain-like)	0	Direct
Aminomethyltransferase beta-barrel domain	0	Direct
PDI-like	0	Direct
D-aminoacid oxidase-like	0	Direct
Guanido kinase N-terminal domain	0	Direct
MSP-like	0	Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain	0	Direct
Delta-sleep-inducing peptide immunoreactive peptide	0	Direct
Variant RING domain	0	Direct
Sterol carrier protein, SCP	0	Direct
Alanine racemase-like, N-terminal domain	0	Direct
Hypoxia-inducible factor HIF ihhibitor (FIH1)	0	Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	0	Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain	0	Direct
Dimeric isocitrate & isopropylmalate dehydrogenases	0	Direct
Choline/Carnitine O-acyltransferase	0	Direct
Branched-chain alpha-keto acid dehydrogenase PP module	0	Direct
Lipovitellin-phosvitin complex, superhelical domain	0	Direct
Moesin tail domain	0	Direct
CAT-like	0	Direct
Apolipoprotein A-I	0	Direct
Eukaryotic ODC-like	0	Direct
NAP-like	0	Direct
PAH2 domain	0	Direct
alpha-catenin/vinculin	0	Direct
Amidase signature (AS) enzymes	0	Direct
MAPEG domain	0	Direct
TB module/8-cys domain	0	Direct
alpha-ketoacid dehydrogenase kinase, C-terminal domain	0	Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	0	Direct
Troponin I	0	Direct
Fibrinogen coiled-coil and central regions	0	Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions	0	Direct
Mitochondrial cytochrome c oxidase subunit VIIa	0	Direct
Threonyl-tRNA synthetase (ThrRS), second 'additional' domain	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Ribosomal protein L3	0	Direct
AAT-like	0	Direct
Lectin leg-like	0	Direct
Chromo barrel domain	0	Direct
BSD domain	0	Direct
Malic enzyme N-domain	0	Direct
Phosphoribosylpyrophosphate synthetase-like	0	Direct
N-acetylmuramoyl-L-alanine amidase-like	0	Direct
Steroid-binding domain	0	Direct
Ran-binding domain	0	Direct
S-adenosylhomocystein hydrolase	0	Direct
DJ-1/PfpI	0	Direct
Noncollagenous (NC1) domain of collagen IV	0	Direct
Transferrin	0	Direct
Nop domain	0	Direct
Anticodon-binding domain of Class II aaRS	0	Direct
Troponin T	0	Direct
Surp module (SWAP domain)	0	Direct
Cullin repeat	0	Direct
Serine carboxypeptidase-like	0	Direct
DnaJ/Hsp40 cysteine-rich domain	0	Direct
Succinyl-CoA synthetase domains	0	Direct
AraD-like aldolase/epimerase	0	Direct
Clathrin adaptor appendage, alpha and beta chain-specific domain	0	Direct
Canonical RBD	0.0001729	Direct
Tyrosine-dependent oxidoreductases	0.0004053	Direct
UBC-related	0.0006193	Direct
LIM domain	0.001318	Inherited
Actin/HSP70	0.003839	Inherited
GABA-aminotransferase-like	0.008105	Inherited
ALDH-like	0.01719	Inherited
Leukotriene A4 hydrolase N-terminal domain	0.03206	Inherited
SMAD domain	0.07489	Inherited
Eukaryotic proteases	0.107	Inherited
Complement components	0.1086	Inherited
SMAD MH1 domain	0.1086	Inherited
Class I aldolase	0.1086	Inherited
Parvalbumin	0.1561	Inherited
Leukotriene A4 hydrolase catalytic domain	0.1636	Inherited
Glutathione peroxidase-like	0.1875	Inherited
LDH N-terminal domain-like	0.2248	Inherited
Linker histone H1/H5	0.2248	Inherited
Lactate & malate dehydrogenases, C-terminal domain	0.2248	Inherited
Paired domain	0.2939	Inherited
WD40-repeat	0.2957	Inherited
Erythroid transcription factor GATA-1	0.3056	Inherited
Extracellular domain of cell surface receptors	0.4823	Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain	0.5027	Inherited
HMG-box	0.5242	Inherited
Intermediate filament protein, coiled coil region	0.5295	Inherited
28-residue LRR	0.5484	Inherited
Spectrin repeat	0.5647	Inherited
Translational machinery components	0.5958	Inherited
T-box	0.6889	Inherited
Calmodulin-like	0.6949	Inherited
Tropomyosin	0.7543	Inherited
Forkhead DNA-binding domain	0.8752	Inherited
Growth factor receptor domain	0.8942	Inherited
Frizzled cysteine-rich domain	0.9022	Inherited
HLH, helix-loop-helix DNA-binding domain	0.9205	Inherited
Homeodomain	1	Inherited
Transforming growth factor (TGF)-beta	1	Inherited
Rhodopsin-like	1	Inherited
Fibroblast growth factors (FGF)	1	Inherited

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Supra-domain (including individual superfamily)

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Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
Cullin repeat-like	0	Direct
SCP-like	0	Direct
Hedgehog/DD-peptidase	0	Direct
PLP-binding barrel	0	Direct
Surp module (SWAP domain)	0	Direct
Mitochondrial cytochrome c oxidase subunit VIIa	0	Direct
CoA-dependent acyltransferases	0	Direct
Nop domain	0	Direct
F1F0 ATP synthase subunit C	0	Direct
Thiolase-like	0	Direct
DnaJ/Hsp40 cysteine-rich domain	0	Direct
4Fe-4S ferredoxins	0	Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain	0	Direct
IP3 receptor type 1 binding core, domain 2	0	Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	0	Direct
N-acetylmuramoyl-L-alanine amidase-like	0	Direct
Mannose 6-phosphate receptor domain	0	Direct
Succinyl-CoA synthetase domains	0	Direct
Aminomethyltransferase beta-barrel domain	0	Direct
TK C-terminal domain-like	0	Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions	0	Direct
Moesin tail domain	0	Direct
eIF1-like	0	Direct
Fibrinogen coiled-coil and central regions	0	Direct
Apolipoprotein A-I	0	Direct
Subunits of heterodimeric actin filament capping protein Capz	0	Direct
Guanido kinase N-terminal domain	0	Direct
TGS-like	0	Direct
Isocitrate/Isopropylmalate dehydrogenase-like	0	Direct
FAS1 domain	0	Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	0	Direct
RmlC-like cupins	0	Direct
BSD domain-like	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
SRF-like	0	Direct
Bacterial exopeptidase dimerisation domain	0	Direct
NAP-like	0	Direct
Lipovitellin-phosvitin complex, superhelical domain	0	Direct
Plakin repeat	0	Direct
Glutamine synthetase/guanido kinase	0	Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain	0	Direct
PAH2 domain	0	Direct
MAPEG domain-like	0	Direct
Mib/herc2 domain-like	0	Direct
Amidase signature (AS) enzymes	0	Direct
HRDC-like	0	Direct
Troponin coil-coiled subunits	0	Direct
AraD/HMP-PK domain-like	0	Direct
ACP-like	0	Direct
ADP-ribosylglycohydrolase	0	Direct
TB module/8-cys domain	0	Direct
Alanine racemase C-terminal domain-like	0	Direct
MHC antigen-recognition domain	0	Direct
Delta-sleep-inducing peptide immunoreactive peptide	0	Direct
NAD(P)-binding Rossmann-fold domains	0.00005827	Direct
PLP-dependent transferases	0.0001633	Direct
UBC-like	0.001927	Inherited
RNA-binding domain, RBD	0.004687	Inherited
ALDH-like	0.01352	Inherited
Thiamin diphosphate-binding fold (THDP-binding)	0.01939	Inherited
Actin-like ATPase domain	0.02061	Inherited
Annexin	0.02945	Inherited
Orange domain-like	0.04427	Inherited
Translation proteins SH3-like domain	0.07201	Inherited
SMAD MH1 domain	0.09797	Inherited
Trypsin-like serine proteases	0.1024	Inherited
Leukotriene A4 hydrolase N-terminal domain	0.1041	Inherited
Thioredoxin-like	0.121	Inherited
WD40 repeat-like	0.136	Inherited
Zn-binding ribosomal proteins	0.1433	Inherited
Alpha-macroglobulin receptor domain	0.1433	Inherited
Translational machinery components	0.1433	Inherited
Glucocorticoid receptor-like (DNA-binding domain)	0.1667	Inherited
LDH C-terminal domain-like	0.2071	Inherited
SMAD/FHA domain	0.2584	Inherited
Actin depolymerizing proteins	0.2726	Inherited
"Winged helix" DNA-binding domain	0.281	Inherited
GINS helical bundle-like	0.2961	Inherited
Snake toxin-like	0.4314	Inherited
HMG-box	0.4645	Inherited
Intermediate filament protein, coiled coil region	0.4765	Inherited
p53-like transcription factors	0.4765	Inherited
Spectrin repeat	0.5134	Inherited
Tropomyosin	0.5163	Inherited
EF-hand	0.6549	Inherited
EGF/Laminin	0.6971	Inherited
PYP-like sensor domain (PAS domain)	0.7533	Inherited
HLH, helix-loop-helix DNA-binding domain	0.858	Inherited
Frizzled cysteine-rich domain	0.8711	Inherited
Growth factor receptor domain	0.8899	Inherited
Cystine-knot cytokines	1	Inherited
Family A G protein-coupled receptor-like	1	Inherited
Homeodomain-like	1	Inherited
Immunoglobulin	1	Inherited
Cytokine	1	Inherited

(show details)

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
82109,82109 82109 - MIR domain 82109 - MIR domain	0	Direct
57196,57581 57196 - EGF/Laminin 57581 - TB module/8-cys domain	0	Direct
57184,49899 57184 - Growth factor receptor domain 49899 - Concanavalin A-like lectins/glucanases	0	Direct
54534,47473 54534 - FKBP-like 47473 - EF-hand	0	Direct
54403,54403 54403 - Cystatin/monellin 54403 - Cystatin/monellin	0	Direct
51419,50621 51419 - PLP-binding barrel 50621 - Alanine racemase C-terminal domain-like	0	Direct
55550,50729 55550 - SH2 domain 50729 - PH domain-like	0	Direct
49899,52540 49899 - Concanavalin A-like lectins/glucanases 52540 - P-loop containing nucleoside triphosphate hydrolases	0	Direct
52518,52922 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52922 - TK C-terminal domain-like	0	Direct
53187,55031 53187 - Zn-dependent exopeptidases 55031 - Bacterial exopeptidase dimerisation domain	0	Direct
51230,47005 51230 - Single hybrid motif 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	0	Direct
57196,50494 57196 - EGF/Laminin 50494 - Trypsin-like serine proteases	0	Direct
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like	0	Direct
103025,101790 103025 - Folate-binding domain 101790 - Aminomethyltransferase beta-barrel domain	0	Direct
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
57581,57184 57581 - TB module/8-cys domain 57184 - Growth factor receptor domain	0	Direct
47473,103506 47473 - EF-hand 103506 - Mitochondrial carrier	0	Direct
56059,52210 56059 - Glutathione synthetase ATP-binding domain-like 52210 - Succinyl-CoA synthetase domains	0	Direct
74788,75632 74788 - Cullin repeat-like 75632 - Cullin homology domain	0	Direct
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain	0	Direct
69012,55874 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	0	Direct
47005,52777 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 52777 - CoA-dependent acyltransferases	0	Direct
81995,81811 81995 - beta-sandwich domain of Sec23/24 81811 - Helical domain of Sec23/24	0	Direct
53738,55957 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain	0	Direct
57184,57581 57184 - Growth factor receptor domain 57581 - TB module/8-cys domain	0	Direct
53901,53901 53901 - Thiolase-like 53901 - Thiolase-like	0	Direct
82895,57424 82895 - TSP-1 type 1 repeat 57424 - LDL receptor-like module	0	Direct
75399,75399 75399 - Plakin repeat 75399 - Plakin repeat	0	Direct
53300,81995 53300 - vWA-like 81995 - beta-sandwich domain of Sec23/24	0	Direct
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain	0	Direct
47095,47095 47095 - HMG-box 47095 - HMG-box	0	Direct
48034,55931 48034 - Guanido kinase N-terminal domain 55931 - Glutamine synthetase/guanido kinase	0	Direct
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin	0	Direct
57424,57184 57424 - LDL receptor-like module 57184 - Growth factor receptor domain	0	Direct
54452,48726 54452 - MHC antigen-recognition domain 48726 - Immunoglobulin	0	Direct
54534,54534 54534 - FKBP-like 54534 - FKBP-like	0	Direct
47661,58038 47661 - t-snare proteins 58038 - SNARE fusion complex	0	Direct
52087,101576 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain	0	Direct
81271,55186 81271 - TGS-like 55186 - ThrRS/AlaRS common domain	0	Direct
48371,46785 48371 - ARM repeat 46785 - "Winged helix" DNA-binding domain	0	Direct
53850,53850 53850 - Periplasmic binding protein-like II 53850 - Periplasmic binding protein-like II	0	Direct
57603,57440 57603 - FnI-like domain 57440 - Kringle-like	0	Direct
54631,54631 54631 - CBS-domain pair 54631 - CBS-domain pair	0	Direct
57581,57196 57581 - TB module/8-cys domain 57196 - EGF/Laminin	0	Direct
54160,57850 54160 - Chromo domain-like 57850 - RING/U-box	0	Direct
50729,55550 50729 - PH domain-like 55550 - SH2 domain	0	Direct
57938,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain	0	Direct
55021,56534 55021 - ACT-like 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	0	Direct
55486,48371 55486 - Metalloproteases ("zincins"), catalytic domain 48371 - ARM repeat	0	Direct
57630,57196 57630 - GLA-domain 57196 - EGF/Laminin	0	Direct
46565,57938 46565 - Chaperone J-domain 57938 - DnaJ/Hsp40 cysteine-rich domain	0	Direct
57924,57924 57924 - Inhibitor of apoptosis (IAP) repeat 57924 - Inhibitor of apoptosis (IAP) repeat	0	Direct
82109,100909 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2	0	Direct
82153,82153 82153 - FAS1 domain 82153 - FAS1 domain	0	Direct
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases	0	Direct
54236,50729 54236 - Ubiquitin-like 50729 - PH domain-like	0	Direct
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain)	0.0006951	Direct
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD	0.002612	Inherited
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain	0.009095	Inherited
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like	0.04427	Inherited
63737,55486 63737 - Leukotriene A4 hydrolase N-terminal domain 55486 - Metalloproteases ("zincins"), catalytic domain	0.1041	Inherited
103657,50729 103657 - BAR/IMD domain-like 50729 - PH domain-like	0.151	Inherited
46966,47473 46966 - Spectrin repeat 47473 - EF-hand	0.2071	Inherited
52518,52518 52518 - Thiamin diphosphate-binding fold (THDP-binding) 52518 - Thiamin diphosphate-binding fold (THDP-binding)	0.2071	Inherited
51735,56327 51735 - NAD(P)-binding Rossmann-fold domains 56327 - LDH C-terminal domain-like	0.2071	Inherited
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0.2071	Inherited
50494,50494 50494 - Trypsin-like serine proteases 50494 - Trypsin-like serine proteases	0.2071	Inherited
48726,56436 48726 - Immunoglobulin 56436 - C-type lectin-like	0.2961	Inherited
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0.3192	Inherited
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin	0.325	Inherited
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain)	0.3787	Inherited
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I)	0.4083	Inherited
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat	0.4637	Inherited
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain)	0.7648	Inherited
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers	1	Inherited

(show details)

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
50729,55550,56112 50729 - PH domain-like 55550 - SH2 domain 56112 - Protein kinase-like (PK-like)	0	Direct
54791,54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I)	0	Direct
57938,49493,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain	0	Direct
63737,55486,48371 63737 - Leukotriene A4 hydrolase N-terminal domain 55486 - Metalloproteases ("zincins"), catalytic domain 48371 - ARM repeat	0	Direct
57196,57581,57196 57196 - EGF/Laminin 57581 - TB module/8-cys domain 57196 - EGF/Laminin	0	Direct
57581,57196,57581 57581 - TB module/8-cys domain 57196 - EGF/Laminin 57581 - TB module/8-cys domain	0	Direct
57424,57424,57184 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57184 - Growth factor receptor domain	0	Direct
53300,81995,81811 53300 - vWA-like 81995 - beta-sandwich domain of Sec23/24 81811 - Helical domain of Sec23/24	0	Direct
57196,57581,57184 57196 - EGF/Laminin 57581 - TB module/8-cys domain 57184 - Growth factor receptor domain	0	Direct
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like	0	Direct
57196,49854,57535 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain 57535 - Complement control module/SCR domain	0	Direct
56436,56436,56436 56436 - C-type lectin-like 56436 - C-type lectin-like 56436 - C-type lectin-like	0	Direct
57630,57196,57196 57630 - GLA-domain 57196 - EGF/Laminin 57196 - EGF/Laminin	0	Direct
57581,57184,57581 57581 - TB module/8-cys domain 57184 - Growth factor receptor domain 57581 - TB module/8-cys domain	0	Direct
57581,57196,57196 57581 - TB module/8-cys domain 57196 - EGF/Laminin 57196 - EGF/Laminin	0	Direct
46565,57938,49493 46565 - Chaperone J-domain 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain	0	Direct
81995,81811,82754 81995 - beta-sandwich domain of Sec23/24 81811 - Helical domain of Sec23/24 82754 - C-terminal, gelsolin-like domain of Sec23/24	0	Direct
53738,53738,55957 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain	0	Direct
52058,52058,52058 52058 - L domain-like 52058 - L domain-like 52058 - L domain-like	0	Direct
50249,50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins	0	Direct
57196,57184,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain	0	Direct
57196,57196,57581 57196 - EGF/Laminin 57196 - EGF/Laminin 57581 - TB module/8-cys domain	0	Direct
54160,57850,57845 54160 - Chromo domain-like 57850 - RING/U-box 57845 - B-box zinc-binding domain	0	Direct
52833,52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like 52833 - Thioredoxin-like	0	Direct
46938,52087,101576 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain 101576 - Supernatant protein factor (SPF), C-terminal domain	0	Direct
74788,75632,46785 74788 - Cullin repeat-like 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain	0	Direct
82109,82109,100909 82109 - MIR domain 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2	0	Direct
51230,47005,52777 51230 - Single hybrid motif 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 52777 - CoA-dependent acyltransferases	0	Direct
57184,57581,57196 57184 - Growth factor receptor domain 57581 - TB module/8-cys domain 57196 - EGF/Laminin	0	Direct
57424,57184,63825 57424 - LDL receptor-like module 57184 - Growth factor receptor domain 63825 - YWTD domain	0	Direct
55550,56112,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) 56112 - Protein kinase-like (PK-like)	0	Direct
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain)	0.02166	Inherited
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat	0.1845	Inherited
46966,46966,47473 46966 - Spectrin repeat 46966 - Spectrin repeat 47473 - EF-hand	0.2071	Inherited
48726,56436,56436 48726 - Immunoglobulin 56436 - C-type lectin-like 56436 - C-type lectin-like	0.2961	Inherited
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0.3787	Inherited
47459,55785,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain)	0.4688	Inherited
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin	0.8438	Inherited

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Xenopus ANatomical entity (XAN): anatomical cluster

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Supra-domain (including individual superfamily)