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Xenopus DEvelopment stage (XDE): climax stage
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this XA term (SDXA level: Moderately Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Dimeric alpha+beta barrel | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| UBC-like | 0.00044 | DIRECT |
| Serpins | 0.0006321 | DIRECT |
| Actin depolymerizing proteins | 0.001627 | INHERITED FROM: NF stage 66 |
| RNA-binding domain, RBD | 0.008841 | INHERITED FROM: NF stage 66 |
| Spectrin repeat | 0.0358 | INHERITED FROM: NF stage 66 |
| FAD-linked reductases, C-terminal domain | 0.06788 | INHERITED FROM: NF stage 62 |
| Translation proteins SH3-like domain | 0.1253 | INHERITED FROM: NF stage 66 |
| gamma-Crystallin-like | 0.1666 | INHERITED FROM: NF stage 62 |
| Thioredoxin-like | 0.3196 | INHERITED FROM: NF stage 66 |
| Growth factor receptor domain | 0.7458 | INHERITED FROM: NF stage 60 |
| Homeodomain-like | 1 | INHERITED FROM: NF stage 65 || NF stage 63 |
| Cytochrome P450 | 1 | INHERITED FROM: NF stage 62 |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Synuclein | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Dimeric alpha+beta barrel | 0 | Direct |
| Stathmin | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Tim10-like | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | Direct |
| ACP-like | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Proteasome activator | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| FF domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| SIS domain | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| BSD domain-like | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| Notch domain | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| eIF1-like | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| PEBP-like | 0 | Direct |
| UBC-like | 0.00044 | Direct |
| Serpins | 0.0006321 | Direct |
| Actin depolymerizing proteins | 0.001627 | Inherited |
| RNA-binding domain, RBD | 0.008841 | Inherited |
| Spectrin repeat | 0.0358 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.06788 | Inherited |
| Translation proteins SH3-like domain | 0.1253 | Inherited |
| gamma-Crystallin-like | 0.1666 | Inherited |
| Thioredoxin-like | 0.3196 | Inherited |
| Growth factor receptor domain | 0.7458 | Inherited |
| Homeodomain-like | 1 | Inherited |
| Cytochrome P450 | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this XA term (Not in SDXA)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| Translation initiation factor eIF4e | 0 | DIRECT |
| Ferritin | 0 | DIRECT |
| Lipoxigenase N-terminal domain | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| ENTH domain | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
| APC10-like | 0 | DIRECT |
| Anticodon-binding domain | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| LDH N-terminal domain-like | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Cofactor-dependent phosphoglycerate mutase | 0 | DIRECT |
| Phosphatidylethanolamine binding protein | 0 | DIRECT |
| PUA domain | 0 | DIRECT |
| Parvalbumin | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| HD domain | 0 | DIRECT |
| Cytochrome b5 | 0 | DIRECT |
| Thrombospondin C-terminal domain | 0 | DIRECT |
| GS domain | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| HCDH C-domain-like | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| CUE domain | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| Gonadodropin/Follitropin | 0 | DIRECT |
| TRASH domain | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| NIPSNAP | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Phenylalanine metabolism regulatory domain | 0 | DIRECT |
| Autophagin-like | 0 | DIRECT |
| Netrin-like domain (NTR/C345C module) | 0 | DIRECT |
| Alpha-adaptin ear subdomain-like | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| SIAH, seven in absentia homolog | 0 | DIRECT |
| GABARAP-like | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Neurotrophin | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Alanine racemase-like, N-terminal domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| Eukaryotic ODC-like | 0 | DIRECT |
| Tim10/DDP | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Carboxylesterase/thioesterase 1 | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
| Neutral endopeptidase (neprilysin) | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Troponin I | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Ribosomal protein L3 | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| Chromo barrel domain | 0 | DIRECT |
| BSD domain | 0 | DIRECT |
| Malic enzyme N-domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Steroid-binding domain | 0 | DIRECT |
| Noncollagenous (NC1) domain of collagen IV | 0 | DIRECT |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Troponin T | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| UBC-related | 0.000002233 | DIRECT |
| Serpins | 0.000608 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0.00594 | INHERITED FROM: NF stage 62 |
| Canonical RBD | 0.01614 | INHERITED FROM: NF stage 66 |
| L-aminoacid/polyamine oxidase | 0.0324 | INHERITED FROM: NF stage 62 |
| Group II chaperonin (CCT, TRIC), apical domain | 0.07214 | INHERITED FROM: NF stage 66 |
| Crystallins/Ca-binding development proteins | 0.161 | INHERITED FROM: NF stage 62 |
| Cytochrome P450 | 0.999 | INHERITED FROM: NF stage 62 |
| Homeodomain | 1 | INHERITED FROM: NF stage 65 || NF stage 63 |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| Stathmin | 0 | Direct |
| Translation initiation factor eIF4e | 0 | Direct |
| Ferritin | 0 | Direct |
| Lipoxigenase N-terminal domain | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| ENTH domain | 0 | Direct |
| LeuD-like | 0 | Direct |
| Phosphoglucomutase, C-terminal domain | 0 | Direct |
| APC10-like | 0 | Direct |
| Anticodon-binding domain | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| eIF1-like | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| LDH N-terminal domain-like | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Cofactor-dependent phosphoglycerate mutase | 0 | Direct |
| Phosphatidylethanolamine binding protein | 0 | Direct |
| PUA domain | 0 | Direct |
| Parvalbumin | 0 | Direct |
| Class I aldolase | 0 | Direct |
| HD domain | 0 | Direct |
| Cytochrome b5 | 0 | Direct |
| Thrombospondin C-terminal domain | 0 | Direct |
| GS domain | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| HCDH C-domain-like | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| Fumble-like | 0 | Direct |
| CUE domain | 0 | Direct |
| NagB-like | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| Gonadodropin/Follitropin | 0 | Direct |
| TRASH domain | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| NIPSNAP | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Phenylalanine metabolism regulatory domain | 0 | Direct |
| Autophagin-like | 0 | Direct |
| Netrin-like domain (NTR/C345C module) | 0 | Direct |
| Alpha-adaptin ear subdomain-like | 0 | Direct |
| IF2B-like | 0 | Direct |
| Notch domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| SIAH, seven in absentia homolog | 0 | Direct |
| GABARAP-like | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Neurotrophin | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Alanine racemase-like, N-terminal domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase PP module | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| CAT-like | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| Eukaryotic ODC-like | 0 | Direct |
| Tim10/DDP | 0 | Direct |
| Type II chitinase | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Carboxylesterase/thioesterase 1 | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
| Neutral endopeptidase (neprilysin) | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Troponin I | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Ribosomal protein L3 | 0 | Direct |
| AAT-like | 0 | Direct |
| Chromo barrel domain | 0 | Direct |
| BSD domain | 0 | Direct |
| Malic enzyme N-domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Steroid-binding domain | 0 | Direct |
| Noncollagenous (NC1) domain of collagen IV | 0 | Direct |
| SH3BGR (SH3-binding, glutamic acid-rich protein-like) | 0 | Direct |
| Synuclein | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Troponin T | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Clathrin adaptor appendage, alpha and beta chain-specific domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| FF domain | 0 | Direct |
| UBC-related | 0.000002233 | Direct |
| Serpins | 0.000608 | Direct |
| FAD-linked reductases, N-terminal domain | 0.00594 | Inherited |
| Canonical RBD | 0.01614 | Inherited |
| L-aminoacid/polyamine oxidase | 0.0324 | Inherited |
| Group II chaperonin (CCT, TRIC), apical domain | 0.07214 | Inherited |
| Crystallins/Ca-binding development proteins | 0.161 | Inherited |
| Cytochrome P450 | 0.999 | Inherited |
| Homeodomain | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this XA term (Not in SPXA)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| LDH C-terminal domain-like | 0 | DIRECT |
| 14-3-3 protein | 0 | DIRECT |
| PLP-binding barrel | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Dimeric alpha+beta barrel | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| TSP type-3 repeat | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0 | DIRECT |
| Mediator hinge subcomplex-like | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Synuclein | 0 | DIRECT |
| Alpha-L RNA-binding motif | 0 | DIRECT |
| FF domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| PEBP-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Thyroglobulin type-1 domain | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| SIS domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
| Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Moesin tail domain | 0 | DIRECT |
| eIF1-like | 0 | DIRECT |
| A heparin-binding domain | 0 | DIRECT |
| USP8 N-terminal domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Fibrinogen coiled-coil and central regions | 0 | DIRECT |
| Apolipoprotein A-I | 0 | DIRECT |
| I/LWEQ domain | 0 | DIRECT |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| BSD domain-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Stathmin | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Proteasome activator | 0 | DIRECT |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Tim10-like | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Troponin coil-coiled subunits | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Ribosomal proteins S24e, L23 and L15e | 0 | DIRECT |
| TB module/8-cys domain | 0 | DIRECT |
| Alanine racemase C-terminal domain-like | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | DIRECT |
| VHP, Villin headpiece domain | 0 | DIRECT |
| UBC-like | 0.0002967 | DIRECT |
| Serpins | 0.0004303 | DIRECT |
| Actin depolymerizing proteins | 0.001115 | INHERITED FROM: NF stage 66 |
| RNA-binding domain, RBD | 0.006245 | INHERITED FROM: NF stage 66 |
| NTF2-like | 0.01756 | INHERITED FROM: NF stage 64 |
| Spectrin repeat | 0.02698 | INHERITED FROM: NF stage 66 |
| FAD-linked reductases, C-terminal domain | 0.05325 | INHERITED FROM: NF stage 62 |
| Translation proteins SH3-like domain | 0.1039 | INHERITED FROM: NF stage 66 |
| gamma-Crystallin-like | 0.1413 | INHERITED FROM: NF stage 62 |
| Thioredoxin-like | 0.2799 | INHERITED FROM: NF stage 66 |
| Growth factor receptor domain | 0.7038 | INHERITED FROM: NF stage 60 |
| Cytochrome P450 | 1 | INHERITED FROM: NF stage 62 |
| Homeodomain-like | 1 | INHERITED FROM: NF stage 65 || NF stage 63 |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Zn-binding ribosomal proteins | 0 | Direct |
| LDH C-terminal domain-like | 0 | Direct |
| 14-3-3 protein | 0 | Direct |
| PLP-binding barrel | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Dimeric alpha+beta barrel | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| TSP type-3 repeat | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| NagB/RpiA/CoA transferase-like | 0 | Direct |
| Mediator hinge subcomplex-like | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Synuclein | 0 | Direct |
| Alpha-L RNA-binding motif | 0 | Direct |
| FF domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| PEBP-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Thyroglobulin type-1 domain | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| SIS domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
| Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Moesin tail domain | 0 | Direct |
| eIF1-like | 0 | Direct |
| A heparin-binding domain | 0 | Direct |
| USP8 N-terminal domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Fibrinogen coiled-coil and central regions | 0 | Direct |
| Apolipoprotein A-I | 0 | Direct |
| I/LWEQ domain | 0 | Direct |
| Subunits of heterodimeric actin filament capping protein Capz | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| BSD domain-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Stathmin | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Proteasome activator | 0 | Direct |
| Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Tim10-like | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Troponin coil-coiled subunits | 0 | Direct |
| ACP-like | 0 | Direct |
| Ribosomal proteins S24e, L23 and L15e | 0 | Direct |
| TB module/8-cys domain | 0 | Direct |
| Alanine racemase C-terminal domain-like | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| Notch domain | 0 | Direct |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 0 | Direct |
| VHP, Villin headpiece domain | 0 | Direct |
| UBC-like | 0.0002967 | Direct |
| Serpins | 0.0004303 | Direct |
| Actin depolymerizing proteins | 0.001115 | Inherited |
| RNA-binding domain, RBD | 0.006245 | Inherited |
| NTF2-like | 0.01756 | Inherited |
| Spectrin repeat | 0.02698 | Inherited |
| FAD-linked reductases, C-terminal domain | 0.05325 | Inherited |
| Translation proteins SH3-like domain | 0.1039 | Inherited |
| gamma-Crystallin-like | 0.1413 | Inherited |
| Thioredoxin-like | 0.2799 | Inherited |
| Growth factor receptor domain | 0.7038 | Inherited |
| Cytochrome P450 | 1 | Inherited |
| Homeodomain-like | 1 | Inherited |
(show details)
Supra-domains annotated to this XA term (Not in SPXA)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
57196,100895
57196 - EGF/Laminin
100895 - Kazal-type serine protease inhibitors | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | DIRECT |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | DIRECT |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | DIRECT |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | DIRECT |
46966,47473
46966 - Spectrin repeat
47473 - EF-hand | 0 | DIRECT |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0 | DIRECT |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | DIRECT |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | DIRECT |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | DIRECT |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | DIRECT |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | DIRECT |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | DIRECT |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
47473,57850
47473 - EF-hand
57850 - RING/U-box | 0 | DIRECT |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | DIRECT |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
50156,50729
50156 - PDZ domain-like
50729 - PH domain-like | 0 | DIRECT |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54160,57850
54160 - Chromo domain-like
57850 - RING/U-box | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
103657,50044
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | DIRECT |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | DIRECT |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0.03852 | INHERITED FROM: NF stage 66 |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.07227 | INHERITED FROM: NF stage 62 |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0.2504 | INHERITED FROM: NF stage 62 |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.2504 | INHERITED FROM: NF stage 62 |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
103647,49899
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57196,57581
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
100895,100895
100895 - Kazal-type serine protease inhibitors
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
57196,100895
57196 - EGF/Laminin
100895 - Kazal-type serine protease inhibitors | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
49348,55711
49348 - Clathrin adaptor appendage domain
55711 - Subdomain of clathrin and coatomer appendage domain | 0 | Direct |
54403,54403
54403 - Cystatin/monellin
54403 - Cystatin/monellin | 0 | Direct |
57184,57610
57184 - Growth factor receptor domain
57610 - Thyroglobulin type-1 domain | 0 | Direct |
51419,50621
51419 - PLP-binding barrel
50621 - Alanine racemase C-terminal domain-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
50044,48350
50044 - SH3-domain
48350 - GTPase activation domain, GAP | 0 | Direct |
46966,47473
46966 - Spectrin repeat
47473 - EF-hand | 0 | Direct |
100895,47473
100895 - Kazal-type serine protease inhibitors
47473 - EF-hand | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
49562,53300
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
53300 - vWA-like | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
57581,57184
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
47473,103506
47473 - EF-hand
103506 - Mitochondrial carrier | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
64593,64593
64593 - Intermediate filament protein, coiled coil region
64593 - Intermediate filament protein, coiled coil region | 0 | Direct |
56491,89811
56491 - A heparin-binding domain
89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 0 | Direct |
57196,90193
57196 - EGF/Laminin
90193 - Notch domain | 0 | Direct |
56436,57535
56436 - C-type lectin-like
57535 - Complement control module/SCR domain | 0 | Direct |
57184,57603
57184 - Growth factor receptor domain
57603 - FnI-like domain | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
81995,81811
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0 | Direct |
57184,57581
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
75399,75399
75399 - Plakin repeat
75399 - Plakin repeat | 0 | Direct |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
53300,81995
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24 | 0 | Direct |
47095,47095
47095 - HMG-box
47095 - HMG-box | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
63825,57196
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
57424,57184
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
47473,57850
47473 - EF-hand
57850 - RING/U-box | 0 | Direct |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 0 | Direct |
82754,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
50156,50729
50156 - PDZ domain-like
50729 - PH domain-like | 0 | Direct |
57196,63825
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
48371,46785
48371 - ARM repeat
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57581,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
49785,49899
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54160,57850
54160 - Chromo domain-like
57850 - RING/U-box | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
103657,50044
103657 - BAR/IMD domain-like
50044 - SH3-domain | 0 | Direct |
81698,81698
81698 - FF domain
81698 - FF domain | 0 | Direct |
53300,49899
53300 - vWA-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0.03852 | Inherited |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 0.07227 | Inherited |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0.2504 | Inherited |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.2504 | Inherited |
(show details)
Supra-domains annotated to this XA term (Not in SPXA)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | DIRECT |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | DIRECT |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | DIRECT |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | DIRECT |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
49785,49785,49899
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | DIRECT |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | DIRECT |
54160,57850,57845
54160 - Chromo domain-like
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | DIRECT |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | DIRECT |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | DIRECT |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | DIRECT |
46966,46966,47473
46966 - Spectrin repeat
46966 - Spectrin repeat
47473 - EF-hand | 0 | DIRECT |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.09464 | INHERITED FROM: NF stage 62 |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
54791,54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
63825,57196,63825
63825 - YWTD domain
57196 - EGF/Laminin
63825 - YWTD domain | 0 | Direct |
57196,57581,57196
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57581,57196,57581
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
57424,57424,57184
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57184 - Growth factor receptor domain | 0 | Direct |
53300,81995,81811
53300 - vWA-like
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24 | 0 | Direct |
57196,57581,57184
57196 - EGF/Laminin
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
57581,57184,57581
57581 - TB module/8-cys domain
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain | 0 | Direct |
57581,57196,57196
57581 - TB module/8-cys domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
82754,55753,55753
82754 - C-terminal, gelsolin-like domain of Sec23/24
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
103647,103647,49899
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
81995,81811,82754
81995 - beta-sandwich domain of Sec23/24
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
49785,49785,49899
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47220,47220,47220
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like
47220 - alpha-catenin/vinculin-like | 0 | Direct |
47769,47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
50249,50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
57196,57184,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57196,57196,57581
57196 - EGF/Laminin
57196 - EGF/Laminin
57581 - TB module/8-cys domain | 0 | Direct |
57196,63825,57196
57196 - EGF/Laminin
63825 - YWTD domain
57196 - EGF/Laminin | 0 | Direct |
54160,57850,57845
54160 - Chromo domain-like
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | Direct |
51230,47005,52777
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
103647,103647,103647
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat
103647 - TSP type-3 repeat | 0 | Direct |
57184,57581,57196
57184 - Growth factor receptor domain
57581 - TB module/8-cys domain
57196 - EGF/Laminin | 0 | Direct |
57424,57184,63825
57424 - LDL receptor-like module
57184 - Growth factor receptor domain
63825 - YWTD domain | 0 | Direct |
46966,46966,47473
46966 - Spectrin repeat
46966 - Spectrin repeat
47473 - EF-hand | 0 | Direct |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0.09464 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
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