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Yeast Phenotype (YP): stress resistance
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: YP Hierarchy (yeast phenotype from Ascomycete phenotype ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this YP term (Not in SDYP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| SNARE-like | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| YjgF-like | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| YAP1 redox domain | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| DNA repair protein MutS, domain I | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Ribosomal protein S2 | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Ribosomal protein L14 | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| DNA repair protein MutS, domain II | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Ribosomal protein S8 | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| Ribosomal L11/L12e N-terminal domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | DIRECT |
| post-HMGL domain-like | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| POZ domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Family A G protein-coupled receptor-like | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| Ribosomal protein L13 | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| Ribosomal protein L6 | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Translation proteins SH3-like domain | 0.2788 | INHERITED FROM: heat sensitivity |
| Protein kinase-like (PK-like) | 0.6668 | INHERITED FROM: osmotic stress resistance || ionic stress resistance |
| Class II aaRS and biotin synthetases | 0.7021 | INHERITED FROM: heat sensitivity || temperature sensitive growth |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7306 | INHERITED FROM: starvation resistance |
| Cyclophilin-like | 0.8365 | INHERITED FROM: freeze-thaw resistance |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: heat sensitivity || temperature sensitive growth |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| SNARE-like | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| YjgF-like | 0 | Direct |
| HIT-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| KA1-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| YAP1 redox domain | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Aldolase | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Bromodomain | 0 | Direct |
| R3H domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| SAP domain | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| ALDH-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| WW domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| DNA repair protein MutS, domain I | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| PA domain | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Ribosomal protein S2 | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Ribosomal protein L14 | 0 | Direct |
| GYF domain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| DNA repair protein MutS, domain II | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| Kelch motif | 0 | Direct |
| Ras GEF | 0 | Direct |
| Ribosomal protein S8 | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| HMG-box | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| MurD-like peptide ligases, catalytic domain | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Nop domain | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| BRCT domain | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Mss4-like | 0 | Direct |
| Ribosomal L11/L12e N-terminal domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | Direct |
| post-HMGL domain-like | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| CheY-like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| L30e-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| vWA-like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| PR-1-like | 0 | Direct |
| Ribosomal protein L11, C-terminal domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| POZ domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Family A G protein-coupled receptor-like | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| Ribosomal protein L13 | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| Cytochrome c | 0 | Direct |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| HCP-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| Ribosomal protein L6 | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Translation proteins SH3-like domain | 0.2788 | Inherited |
| Protein kinase-like (PK-like) | 0.6668 | Inherited |
| Class II aaRS and biotin synthetases | 0.7021 | Inherited |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7306 | Inherited |
| Cyclophilin-like | 0.8365 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this YP term (Not in SDYP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| PyrH-like | 0 | DIRECT |
| TRAPP components | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| Glucose 6-phosphate dehydrogenase-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| FAD-linked oxidases, N-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| GABA-aminotransferase-like | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| FAD/NAD-linked reductases, N-terminal and central domains | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| MPP-like | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| RNB domain-like | 0 | DIRECT |
| Glycosyl hydrolases family 16 | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| N-type ATP pyrophosphatases | 0 | DIRECT |
| CheY-related | 0 | DIRECT |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
| HMGL-like | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Pseudouridine synthase I TruA | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Ribosomal protein S8 | 0 | DIRECT |
| Lysophospholipase | 0 | DIRECT |
| RING finger domain, C3HC4 | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| PHD domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
| Thiamin biosynthesis kinases | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Ribosomal protein L14e | 0 | DIRECT |
| Tetratricopeptide repeat (TPR) | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| FabD-like | 0 | DIRECT |
| Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
| Ribosomal protein L14 | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| DNA repair protein MutS, domain I | 0 | DIRECT |
| C-terminal domain of ribosomal protein L2 | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Glutathione S-transferase (GST), N-terminal domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| Ribosomal protein L6 | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| Trehalose-6-phosphate synthase, OtsA | 0 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| YjgF/L-PSP | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Ribosomal protein L13 | 0 | DIRECT |
| PDI-like | 0 | DIRECT |
| Ribosomal protein S13 | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Ubiquitin-related | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Bacteriorhodopsin-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| Ribosomal protein S2 | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| La domain | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Folylpolyglutamate synthetase | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| L-aspartase/fumarase | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| Trunk domain of Sec23/24 | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| HAT/Suf repeat | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| UBA domain | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
| ENTH domain | 0 | DIRECT |
| Forkhead DNA-binding domain | 0 | DIRECT |
| GAPDH-like | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Pumilio repeat | 0 | DIRECT |
| Vacuolar sorting protein domain | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Glutathione S-transferase (GST), C-terminal domain | 0 | DIRECT |
| Ribosomal protein L18 and S11 | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Tryptophan biosynthesis enzymes | 0 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| YAP1 redox domain | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| Ribosomal L11/L12e N-terminal domain | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| BCR-homology GTPase activation domain (BH-domain) | 0 | DIRECT |
| DJ-1/PfpI | 0 | DIRECT |
| Ran-binding domain | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Pepsin-like | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
| Gastric lipase | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| Cold shock DNA-binding domain-like | 0.2168 | INHERITED FROM: heat sensitivity || temperature sensitive growth |
| Protein kinases, catalytic subunit | 0.5452 | INHERITED FROM: osmotic stress resistance |
| Thioltransferase | 0.5753 | INHERITED FROM: oxidative stress resistance |
| Tandem AAA-ATPase domain | 0.7051 | INHERITED FROM: radiation resistance |
| 5' to 3' exonuclease catalytic domain | 0.7136 | INHERITED FROM: starvation resistance |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7136 | INHERITED FROM: starvation resistance |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0.7673 | INHERITED FROM: osmotic stress resistance || hyperosmotic stress resistance |
| Glutathione peroxidase-like | 0.8454 | INHERITED FROM: oxidative stress resistance |
| Cyclophilin (peptidylprolyl isomerase) | 0.8814 | INHERITED FROM: freeze-thaw resistance |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| PyrH-like | 0 | Direct |
| TRAPP components | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| Glucose 6-phosphate dehydrogenase-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| FAD-linked oxidases, N-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| GABA-aminotransferase-like | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Bromodomain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| HCP-like | 0 | Direct |
| FAD/NAD-linked reductases, N-terminal and central domains | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Hexokinase | 0 | Direct |
| MPP-like | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| RNB domain-like | 0 | Direct |
| Glycosyl hydrolases family 16 | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| N-type ATP pyrophosphatases | 0 | Direct |
| CheY-related | 0 | Direct |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
| HMGL-like | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Pseudouridine synthase I TruA | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Ribosomal protein S8 | 0 | Direct |
| Lysophospholipase | 0 | Direct |
| RING finger domain, C3HC4 | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| PHD domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| FHA domain | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Cyclin | 0 | Direct |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
| Thiamin biosynthesis kinases | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Class I aldolase | 0 | Direct |
| PA domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Ribosomal protein L14e | 0 | Direct |
| Tetratricopeptide repeat (TPR) | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| FabD-like | 0 | Direct |
| Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
| Ribosomal protein L14 | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| VHS domain | 0 | Direct |
| DNA repair protein MutS, domain I | 0 | Direct |
| C-terminal domain of ribosomal protein L2 | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Glutathione S-transferase (GST), N-terminal domain | 0 | Direct |
| SAP domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| Ribosomal protein L6 | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| Subtilases | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| Trehalose-6-phosphate synthase, OtsA | 0 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| PR-1-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| YjgF/L-PSP | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| UBC-related | 0 | Direct |
| Ribosomal protein L13 | 0 | Direct |
| PDI-like | 0 | Direct |
| Ribosomal protein S13 | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Ubiquitin-related | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Bacteriorhodopsin-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
| ALDH-like | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| Ribosomal protein S2 | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| La domain | 0 | Direct |
| SWIRM domain | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Folylpolyglutamate synthetase | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Ribosomal protein L11, C-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| L-aspartase/fumarase | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| Thiolase-related | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| Trunk domain of Sec23/24 | 0 | Direct |
| WW domain | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| HAT/Suf repeat | 0 | Direct |
| HMG-box | 0 | Direct |
| UBA domain | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Phosphoribulokinase/pantothenate kinase | 0 | Direct |
| ENTH domain | 0 | Direct |
| Forkhead DNA-binding domain | 0 | Direct |
| GAPDH-like | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| GYF domain | 0 | Direct |
| Pumilio repeat | 0 | Direct |
| Vacuolar sorting protein domain | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Glutathione S-transferase (GST), C-terminal domain | 0 | Direct |
| Ribosomal protein L18 and S11 | 0 | Direct |
| Ras GEF | 0 | Direct |
| Tryptophan biosynthesis enzymes | 0 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| YAP1 redox domain | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| LeuD-like | 0 | Direct |
| Ribosomal L11/L12e N-terminal domain | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| BCR-homology GTPase activation domain (BH-domain) | 0 | Direct |
| DJ-1/PfpI | 0 | Direct |
| Ran-binding domain | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Pepsin-like | 0 | Direct |
| NTF2-like | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Reductases | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
| Gastric lipase | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| Cold shock DNA-binding domain-like | 0.2168 | Inherited |
| Protein kinases, catalytic subunit | 0.5452 | Inherited |
| Thioltransferase | 0.5753 | Inherited |
| Tandem AAA-ATPase domain | 0.7051 | Inherited |
| 5' to 3' exonuclease catalytic domain | 0.7136 | Inherited |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7136 | Inherited |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0.7673 | Inherited |
| Glutathione peroxidase-like | 0.8454 | Inherited |
| Cyclophilin (peptidylprolyl isomerase) | 0.8814 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this YP term (Not in SPYP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| RNase III domain-like | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
| HIT/MYND zinc finger-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Ribosomal protein L30p/L7e | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Ribosomal L11/L12e N-terminal domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| DNA repair protein MutS, domain II | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Amidase signature (AS) enzymes | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| Nucleotide-binding domain | 0 | DIRECT |
| YAP1 redox domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Alkaline phosphatase-like | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| Ribosomal protein S2 | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
| YjgF-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| DNA repair protein MutS, domain III | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| L-aspartase-like | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| LuxS/MPP-like metallohydrolase | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
| Tubulin nucleotide-binding domain-like | 0 | DIRECT |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| FMN-binding split barrel | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Zn-finger domain of Sec23/24 | 0 | DIRECT |
| LeuD/IlvD-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Ribosomal protein L6 | 0 | DIRECT |
| DNA repair protein MutS, domain I | 0 | DIRECT |
| DNA-glycosylase | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| HSP20-like chaperones | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Clavaminate synthase-like | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Ribosomal protein L13 | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| ArfGap/RecO-like zinc finger | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Single hybrid motif | 0 | DIRECT |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| POZ domain | 0 | DIRECT |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| RmlC-like cupins | 0 | DIRECT |
| Ribosomal protein L14 | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| post-HMGL domain-like | 0 | DIRECT |
| Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
| Ribosomal protein S8 | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Cation efflux protein transmembrane domain-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Family A G protein-coupled receptor-like | 0 | DIRECT |
| Ribosomal protein L22 | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
| Translation proteins SH3-like domain | 0.2637 | INHERITED FROM: heat sensitivity |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.4259 | INHERITED FROM: ionic stress resistance |
| Protein kinase-like (PK-like) | 0.6529 | INHERITED FROM: osmotic stress resistance || ionic stress resistance |
| Nucleotidyltransferase | 0.6717 | INHERITED FROM: temperature sensitive growth |
| Class II aaRS and biotin synthetases | 0.6882 | INHERITED FROM: heat sensitivity || temperature sensitive growth |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7193 | INHERITED FROM: starvation resistance |
| Cyclophilin-like | 0.8283 | INHERITED FROM: freeze-thaw resistance |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: heat sensitivity || temperature sensitive growth |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| RNase III domain-like | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| WW domain | 0 | Direct |
| Glutathione synthetase ATP-binding domain-like | 0 | Direct |
| HIT/MYND zinc finger-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| HIT-like | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| PR-1-like | 0 | Direct |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | Direct |
| beta-sandwich domain of Sec23/24 | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| The spindle assembly checkpoint protein mad2 | 0 | Direct |
| PP2C-like | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Cytochrome c | 0 | Direct |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
| HRDC-like | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Ribosomal protein L30p/L7e | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| KA1-like | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| CheY-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| Ribosomal L11/L12e N-terminal domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| DNA repair protein MutS, domain II | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Kelch motif | 0 | Direct |
| Amidase signature (AS) enzymes | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| MurD-like peptide ligases, catalytic domain | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| Nucleotide-binding domain | 0 | Direct |
| YAP1 redox domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Alkaline phosphatase-like | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| BRCT domain | 0 | Direct |
| Ribosomal protein S2 | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Adenine nucleotide alpha hydrolases-like | 0 | Direct |
| YjgF-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| DNA repair protein MutS, domain III | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Nop domain | 0 | Direct |
| SAP domain | 0 | Direct |
| L-aspartase-like | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| LuxS/MPP-like metallohydrolase | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| HMG-box | 0 | Direct |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
| Tubulin nucleotide-binding domain-like | 0 | Direct |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| FMN-binding split barrel | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Zn-finger domain of Sec23/24 | 0 | Direct |
| LeuD/IlvD-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Ribosomal protein L6 | 0 | Direct |
| DNA repair protein MutS, domain I | 0 | Direct |
| DNA-glycosylase | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| vWA-like | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| PA domain | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Mss4-like | 0 | Direct |
| HSP20-like chaperones | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Ras GEF | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| HCP-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Clavaminate synthase-like | 0 | Direct |
| GYF domain | 0 | Direct |
| Ribosomal protein L13 | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| ArfGap/RecO-like zinc finger | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Single hybrid motif | 0 | Direct |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | Direct |
| Bromodomain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| POZ domain | 0 | Direct |
| Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
| Aldolase | 0 | Direct |
| RmlC-like cupins | 0 | Direct |
| Ribosomal protein L14 | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Prefoldin | 0 | Direct |
| post-HMGL domain-like | 0 | Direct |
| Ribosomal protein L11, C-terminal domain | 0 | Direct |
| Ribosomal protein S8 | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| NTF2-like | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Cation efflux protein transmembrane domain-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | Direct |
| R3H domain | 0 | Direct |
| L30e-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Family A G protein-coupled receptor-like | 0 | Direct |
| Ribosomal protein L22 | 0 | Direct |
| SNARE-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
| Translation proteins SH3-like domain | 0.2637 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.4259 | Inherited |
| Protein kinase-like (PK-like) | 0.6529 | Inherited |
| Nucleotidyltransferase | 0.6717 | Inherited |
| Class II aaRS and biotin synthetases | 0.6882 | Inherited |
| 5' to 3' exonuclease, C-terminal subdomain | 0.7193 | Inherited |
| Cyclophilin-like | 0.8283 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
(show details)
Supra-domains annotated to this YP term (Not in SPYP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0 | DIRECT |
48371,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
56235,52402
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
56053,56053
56053 - Ribosomal protein L6
56053 - Ribosomal protein L6 | 0 | DIRECT |
54236,57829
54236 - Ubiquitin-like
57829 - Zn-binding ribosomal proteins | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0 | DIRECT |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
50249,50104
50249 - Nucleic acid-binding proteins
50104 - Translation proteins SH3-like domain | 0 | DIRECT |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
54631,51412
54631 - CBS-domain pair
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | DIRECT |
81995,82919
81995 - beta-sandwich domain of Sec23/24
82919 - Zn-finger domain of Sec23/24 | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54747,46906
54747 - Ribosomal L11/L12e N-terminal domain
46906 - Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | DIRECT |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
-9,52954
-9 - PDB
52954 - Class II aaRS ABD-related | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
53150,48334
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III | 0 | DIRECT |
53623,53244
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.4382 | INHERITED FROM: gamma ray resistance |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
52833,52833
52833 - Thioredoxin-like
52833 - Thioredoxin-like | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0 | Direct |
48371,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
56235,52402
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
56053,56053
56053 - Ribosomal protein L6
56053 - Ribosomal protein L6 | 0 | Direct |
54236,57829
54236 - Ubiquitin-like
57829 - Zn-binding ribosomal proteins | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
81811,82754
81811 - Helical domain of Sec23/24
82754 - C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
51905,51905
51905 - FAD/NAD(P)-binding domain
51905 - FAD/NAD(P)-binding domain | 0 | Direct |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
50249,50104
50249 - Nucleic acid-binding proteins
50104 - Translation proteins SH3-like domain | 0 | Direct |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
54631,51412
54631 - CBS-domain pair
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
48371,-7
48371 - ARM repeat
-7 - CATH | 0 | Direct |
81995,82919
81995 - beta-sandwich domain of Sec23/24
82919 - Zn-finger domain of Sec23/24 | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
48334,52540
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
47923,47923
47923 - Ypt/Rab-GAP domain of gyp1p
47923 - Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
51905,56425
51905 - FAD/NAD(P)-binding domain
56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54747,46906
54747 - Ribosomal L11/L12e N-terminal domain
46906 - Ribosomal protein L11, C-terminal domain | 0 | Direct |
82919,53300
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | Direct |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
-9,52954
-9 - PDB
52954 - Class II aaRS ABD-related | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
53150,48334
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III | 0 | Direct |
53623,53244
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.4382 | Inherited |
(show details)
Supra-domains annotated to this YP term (Not in SPYP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
49562,49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
53150,48334,52540
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
81995,82919,53300
81995 - beta-sandwich domain of Sec23/24
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | DIRECT |
57756,57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
48371,52540,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
49562,49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
53150,48334,52540
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
81995,82919,53300
81995 - beta-sandwich domain of Sec23/24
82919 - Zn-finger domain of Sec23/24
53300 - vWA-like | 0 | Direct |
57756,57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
48371,52540,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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