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Yeast Phenotype (YP): resistance to chemicals
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: YP Hierarchy (yeast phenotype from Ascomycete phenotype ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this YP term (SDYP level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| FAD-linked oxidoreductase | 0 | DIRECT |
| YjgF-like | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| YAP1 redox domain | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| DNA repair protein MutS, domain I | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Ribosomal protein L14 | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| DNA repair protein MutS, domain II | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Ribosomal protein S8 | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| Ribosomal L11/L12e N-terminal domain | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
| POZ domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Family A G protein-coupled receptor-like | 0 | DIRECT |
| Ribosomal protein L13 | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| Ribosomal protein L6 | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0.3258 | INHERITED FROM: osmotic stress resistance || ionic stress resistance |
| Subtilisin-like | 0.7955 | INHERITED FROM: acid pH resistance |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| FAD-linked oxidoreductase | 0 | Direct |
| YjgF-like | 0 | Direct |
| HIT-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| KA1-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| YAP1 redox domain | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Bromodomain | 0 | Direct |
| R3H domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| ALDH-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| WW domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| DNA repair protein MutS, domain I | 0 | Direct |
| PA domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Ribosomal protein L14 | 0 | Direct |
| GYF domain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Thiolase-like | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| DNA repair protein MutS, domain II | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| Kelch motif | 0 | Direct |
| Ras GEF | 0 | Direct |
| Ribosomal protein S8 | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| HMG-box | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| MurD-like peptide ligases, catalytic domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Mss4-like | 0 | Direct |
| Ribosomal L11/L12e N-terminal domain | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| CheY-like | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| PR-1-like | 0 | Direct |
| Ribosomal protein L11, C-terminal domain | 0 | Direct |
| POZ domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Family A G protein-coupled receptor-like | 0 | Direct |
| Ribosomal protein L13 | 0 | Direct |
| Cytochrome c | 0 | Direct |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | Direct |
| HCP-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| Ribosomal protein L6 | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Protein kinase-like (PK-like) | 0.3258 | Inherited |
| Subtilisin-like | 0.7955 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this YP term (SDYP level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| MIF4G domain-like | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| PyrH-like | 0 | DIRECT |
| TRAPP components | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| FAD-linked oxidases, N-terminal domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| GABA-aminotransferase-like | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Cofilin-like | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| RNB domain-like | 0 | DIRECT |
| Glycosyl hydrolases family 16 | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| CheY-related | 0 | DIRECT |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
| p120GAP domain-like | 0 | DIRECT |
| ABC transporter transmembrane region | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Pseudouridine synthase I TruA | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Ribosomal protein S8 | 0 | DIRECT |
| Lysophospholipase | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
| Thiamin biosynthesis kinases | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Class I aldolase | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Ribosomal protein L14e | 0 | DIRECT |
| Tetratricopeptide repeat (TPR) | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| FabD-like | 0 | DIRECT |
| Ribosomal protein L14 | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| VHS domain | 0 | DIRECT |
| DNA repair protein MutS, domain I | 0 | DIRECT |
| C-terminal domain of ribosomal protein L2 | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Helical domain of Sec23/24 | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| Ribosomal protein L6 | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| YjgF/L-PSP | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| Ribosomal protein L13 | 0 | DIRECT |
| Ribosomal protein S13 | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Bacteriorhodopsin-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| DNA gyrase/MutL, second domain | 0 | DIRECT |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| La domain | 0 | DIRECT |
| SWIRM domain | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Folylpolyglutamate synthetase | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
| ENTH domain | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Vacuolar sorting protein domain | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Tryptophan biosynthesis enzymes | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| YAP1 redox domain | 0 | DIRECT |
| FAD-linked reductases, N-terminal domain | 0 | DIRECT |
| LeuD-like | 0 | DIRECT |
| Ribosomal L11/L12e N-terminal domain | 0 | DIRECT |
| BCR-homology GTPase activation domain (BH-domain) | 0 | DIRECT |
| DJ-1/PfpI | 0 | DIRECT |
| Ran-binding domain | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Pepsin-like | 0 | DIRECT |
| Reductases | 0 | DIRECT |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| Protein kinases, catalytic subunit | 0.2623 | INHERITED FROM: osmotic stress resistance |
| Thioltransferase | 0.3172 | INHERITED FROM: oxidative stress resistance |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0.5898 | INHERITED FROM: osmotic stress resistance || hyperosmotic stress resistance |
| RecA protein-like (ATPase-domain) | 0.6505 | INHERITED FROM: oxidative stress resistance || alkaline pH resistance |
| Subtilases | 0.7823 | INHERITED FROM: acid pH resistance |
| Glutathione peroxidase-like | 0.8247 | INHERITED FROM: oxidative stress resistance |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| MIF4G domain-like | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| PyrH-like | 0 | Direct |
| TRAPP components | 0 | Direct |
| Sec7 domain | 0 | Direct |
| FAD-linked oxidases, N-terminal domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| GABA-aminotransferase-like | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Bromodomain | 0 | Direct |
| Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Cofilin-like | 0 | Direct |
| HCP-like | 0 | Direct |
| Hexokinase | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| RNB domain-like | 0 | Direct |
| Glycosyl hydrolases family 16 | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| CheY-related | 0 | Direct |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
| p120GAP domain-like | 0 | Direct |
| ABC transporter transmembrane region | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Pseudouridine synthase I TruA | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Ribosomal protein S8 | 0 | Direct |
| Lysophospholipase | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| DNA gyrase/MutL, N-terminal domain | 0 | Direct |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
| Thiamin biosynthesis kinases | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Class I aldolase | 0 | Direct |
| PA domain | 0 | Direct |
| Ribosomal protein L14e | 0 | Direct |
| Tetratricopeptide repeat (TPR) | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| FabD-like | 0 | Direct |
| Ribosomal protein L14 | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| VHS domain | 0 | Direct |
| DNA repair protein MutS, domain I | 0 | Direct |
| C-terminal domain of ribosomal protein L2 | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Helical domain of Sec23/24 | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| Ribosomal protein L6 | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| PR-1-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| YjgF/L-PSP | 0 | Direct |
| UBC-related | 0 | Direct |
| Ribosomal protein L13 | 0 | Direct |
| Ribosomal protein S13 | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Bacteriorhodopsin-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| DNA gyrase/MutL, second domain | 0 | Direct |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
| ALDH-like | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| La domain | 0 | Direct |
| SWIRM domain | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Folylpolyglutamate synthetase | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Ribosomal protein L11, C-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Thiolase-related | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| WW domain | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| HMG-box | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Phosphoribulokinase/pantothenate kinase | 0 | Direct |
| ENTH domain | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| GYF domain | 0 | Direct |
| Vacuolar sorting protein domain | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Ras GEF | 0 | Direct |
| Tryptophan biosynthesis enzymes | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| YAP1 redox domain | 0 | Direct |
| FAD-linked reductases, N-terminal domain | 0 | Direct |
| LeuD-like | 0 | Direct |
| Ribosomal L11/L12e N-terminal domain | 0 | Direct |
| BCR-homology GTPase activation domain (BH-domain) | 0 | Direct |
| DJ-1/PfpI | 0 | Direct |
| Ran-binding domain | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Pepsin-like | 0 | Direct |
| Reductases | 0 | Direct |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| Protein kinases, catalytic subunit | 0.2623 | Inherited |
| Thioltransferase | 0.3172 | Inherited |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0.5898 | Inherited |
| RecA protein-like (ATPase-domain) | 0.6505 | Inherited |
| Subtilases | 0.7823 | Inherited |
| Glutathione peroxidase-like | 0.8247 | Inherited |
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this YP term (SPYP level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| EPT/RTPC-like | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| Calponin-homology domain, CH-domain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
| Acetyl-CoA synthetase-like | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| WW domain | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| Tubulin C-terminal domain-like | 0 | DIRECT |
| PR-1-like | 0 | DIRECT |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Cytochrome c | 0 | DIRECT |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Ribosomal protein L10-like | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| ALDH-like | 0 | DIRECT |
| Ribosomal L11/L12e N-terminal domain | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| DNA repair protein MutS, domain II | 0 | DIRECT |
| Aconitase iron-sulfur domain | 0 | DIRECT |
| Kelch motif | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
| YAP1 redox domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| HMA, heavy metal-associated domain | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| YjgF-like | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Cysteine alpha-hairpin motif | 0 | DIRECT |
| HMG-box | 0 | DIRECT |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| CCCH zinc finger | 0 | DIRECT |
| Chromo domain-like | 0 | DIRECT |
| Endosomal sorting complex assembly domain | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| HD-domain/PDEase-like | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| VPS9 domain | 0 | DIRECT |
| Ribosomal protein L6 | 0 | DIRECT |
| DNA repair protein MutS, domain I | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| PA domain | 0 | DIRECT |
| Cytochrome P450 | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| Mss4-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| Ras GEF | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| HCP-like | 0 | DIRECT |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
| GYF domain | 0 | DIRECT |
| Ribosomal protein L13 | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| POZ domain | 0 | DIRECT |
| Ribosomal protein L14 | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
| Ribosomal protein S8 | 0 | DIRECT |
| Actin depolymerizing proteins | 0 | DIRECT |
| FAD-linked oxidoreductase | 0 | DIRECT |
| Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Family A G protein-coupled receptor-like | 0 | DIRECT |
| HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
| tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| F1F0 ATP synthase subunit C | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.174 | INHERITED FROM: ionic stress resistance |
| Protein kinase-like (PK-like) | 0.3099 | INHERITED FROM: ionic stress resistance || osmotic stress resistance |
| Subtilisin-like | 0.7869 | INHERITED FROM: acid pH resistance |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| EPT/RTPC-like | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| Calponin-homology domain, CH-domain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
| Acetyl-CoA synthetase-like | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| WW domain | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| HIT-like | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| Tubulin C-terminal domain-like | 0 | Direct |
| PR-1-like | 0 | Direct |
| Fe,Mn superoxide dismutase (SOD), C-terminal domain | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| PP2C-like | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Cytochrome c | 0 | Direct |
| DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
| HRDC-like | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Sec7 domain | 0 | Direct |
| DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Ribosomal protein L10-like | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| KA1-like | 0 | Direct |
| CheY-like | 0 | Direct |
| ALDH-like | 0 | Direct |
| Ribosomal L11/L12e N-terminal domain | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| DNA repair protein MutS, domain II | 0 | Direct |
| Aconitase iron-sulfur domain | 0 | Direct |
| Kelch motif | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| MurD-like peptide ligases, catalytic domain | 0 | Direct |
| YAP1 redox domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| HMA, heavy metal-associated domain | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| YjgF-like | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Cysteine alpha-hairpin motif | 0 | Direct |
| HMG-box | 0 | Direct |
| Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
| C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| CCCH zinc finger | 0 | Direct |
| Chromo domain-like | 0 | Direct |
| Endosomal sorting complex assembly domain | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| HD-domain/PDEase-like | 0 | Direct |
| Ferritin-like | 0 | Direct |
| VPS9 domain | 0 | Direct |
| Ribosomal protein L6 | 0 | Direct |
| DNA repair protein MutS, domain I | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| PA domain | 0 | Direct |
| Cytochrome P450 | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| Mss4-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| Ras GEF | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| HCP-like | 0 | Direct |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
| FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
| GYF domain | 0 | Direct |
| Ribosomal protein L13 | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Mitochondrial cytochrome c oxidase subunit IV | 0 | Direct |
| Bromodomain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| POZ domain | 0 | Direct |
| Ribosomal protein L14 | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| Ribosomal protein L11, C-terminal domain | 0 | Direct |
| Ribosomal protein S8 | 0 | Direct |
| Actin depolymerizing proteins | 0 | Direct |
| FAD-linked oxidoreductase | 0 | Direct |
| Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| R3H domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Family A G protein-coupled receptor-like | 0 | Direct |
| HSP40/DnaJ peptide-binding domain | 0 | Direct |
| tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| F1F0 ATP synthase subunit C | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.174 | Inherited |
| Protein kinase-like (PK-like) | 0.3099 | Inherited |
| Subtilisin-like | 0.7869 | Inherited |
(show details)
Supra-domains annotated to this YP term (SPYP level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
48371,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
56053,56053
56053 - Ribosomal protein L6
56053 - Ribosomal protein L6 | 0 | DIRECT |
54236,57829
54236 - Ubiquitin-like
57829 - Zn-binding ribosomal proteins | 0 | DIRECT |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50249,50104
50249 - Nucleic acid-binding proteins
50104 - Translation proteins SH3-like domain | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
54631,51412
54631 - CBS-domain pair
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
54747,46906
54747 - Ribosomal L11/L12e N-terminal domain
46906 - Ribosomal protein L11, C-terminal domain | 0 | DIRECT |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | DIRECT |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | DIRECT |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
53150,48334
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III | 0 | DIRECT |
53623,53244
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
48371,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
-7,52540
-7 - CATH
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
52490,55307
52490 - Tubulin nucleotide-binding domain-like
55307 - Tubulin C-terminal domain-like | 0 | Direct |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
63380,52343
63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
56053,56053
56053 - Ribosomal protein L6
56053 - Ribosomal protein L6 | 0 | Direct |
54236,57829
54236 - Ubiquitin-like
57829 - Zn-binding ribosomal proteins | 0 | Direct |
49493,49493
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50249,50104
50249 - Nucleic acid-binding proteins
50104 - Translation proteins SH3-like domain | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
54631,51412
54631 - CBS-domain pair
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
46565,57938
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55874,54211
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
54631,54631
54631 - CBS-domain pair
54631 - CBS-domain pair | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
57938,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
54747,46906
54747 - Ribosomal L11/L12e N-terminal domain
46906 - Ribosomal protein L11, C-terminal domain | 0 | Direct |
51905,55424
51905 - FAD/NAD(P)-binding domain
55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
53732,52016
53732 - Aconitase iron-sulfur domain
52016 - LeuD/IlvD-like | 0 | Direct |
81333,81333
81333 - F1F0 ATP synthase subunit C
81333 - F1F0 ATP synthase subunit C | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
103657,50729
103657 - BAR/IMD domain-like
50729 - PH domain-like | 0 | Direct |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
53150,48334
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III | 0 | Direct |
53623,53244
53623 - MurD-like peptide ligases, catalytic domain
53244 - MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
52540,90123
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
(show details)
Supra-domains annotated to this YP term (SPYP level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
49562,49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
53150,48334,52540
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
57756,57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | DIRECT |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
48371,52540,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,54980,54211
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
46565,57938,49493
46565 - Chaperone J-domain
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
49562,49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57938,49493,49493
57938 - DnaJ/Hsp40 cysteine-rich domain
49493 - HSP40/DnaJ peptide-binding domain
49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
53150,48334,52540
53150 - DNA repair protein MutS, domain II
48334 - DNA repair protein MutS, domain III
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48371,48371,48371
48371 - ARM repeat
48371 - ARM repeat
48371 - ARM repeat | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
57756,57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
90123,52540,90123
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region | 0 | Direct |
52540,90123,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
90123 - ABC transporter transmembrane region
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
48371,52540,52540
48371 - ARM repeat
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
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