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Yeast Phenotype (YP): fitness
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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: YP Hierarchy (yeast phenotype from Ascomycete phenotype ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this YP term (Not in SDYP)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
Ankyrin repeat | 0 | DIRECT |
FAD-linked oxidoreductase | 0 | DIRECT |
FMN-linked oxidoreductases | 0 | DIRECT |
RBP11-like subunits of RNA polymerase | 0 | DIRECT |
Heme oxygenase-like | 0 | DIRECT |
Cyclophilin-like | 0 | DIRECT |
TGS-like | 0 | DIRECT |
YjgF-like | 0 | DIRECT |
Fumarate reductase respiratory complex transmembrane subunits | 0 | DIRECT |
HIT-like | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
F1F0 ATP synthase subunit C | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
Ribosomal protein L22 | 0 | DIRECT |
The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
Ribosomal protein L30p/L7e | 0 | DIRECT |
eIF1-like | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
S13-like H2TH domain | 0 | DIRECT |
Nucleoporin domain | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
Cation efflux protein transmembrane domain-like | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
KA1-like | 0 | DIRECT |
Radical SAM enzymes | 0 | DIRECT |
ThrRS/AlaRS common domain | 0 | DIRECT |
Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
YAP1 redox domain | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
EPT/RTPC-like | 0 | DIRECT |
Phosphoglycerate mutase-like | 0 | DIRECT |
PEBP-like | 0 | DIRECT |
Concanavalin A-like lectins/glucanases | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
HRDC-like | 0 | DIRECT |
NagB/RpiA/CoA transferase-like | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
GST C-terminal domain-like | 0 | DIRECT |
FMN-binding split barrel | 0 | DIRECT |
Carbohydrate phosphatase | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
L-aspartase-like | 0 | DIRECT |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
Seven-hairpin glycosidases | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
Aldolase | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
LDH C-terminal domain-like | 0 | DIRECT |
Carbamate kinase-like | 0 | DIRECT |
ACT-like | 0 | DIRECT |
FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
R3H domain | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
E set domains | 0 | DIRECT |
SAP domain | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
PLP-binding barrel | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
Nucleotide-binding domain | 0 | DIRECT |
Rudiment single hybrid motif | 0 | DIRECT |
Protein prenylyltransferase | 0 | DIRECT |
GINS helical bundle-like | 0 | DIRECT |
LexA/Signal peptidase | 0 | DIRECT |
PX domain | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
GHMP Kinase, C-terminal domain | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
WW domain | 0 | DIRECT |
PP2C-like | 0 | DIRECT |
DNA-glycosylase | 0 | DIRECT |
Aconitase iron-sulfur domain | 0 | DIRECT |
FKBP-like | 0 | DIRECT |
Cupredoxins | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
Endosomal sorting complex assembly domain | 0 | DIRECT |
Phosphoglucomutase, first 3 domains | 0 | DIRECT |
Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
HMA, heavy metal-associated domain | 0 | DIRECT |
DNA repair protein MutS, domain I | 0 | DIRECT |
Amidase signature (AS) enzymes | 0 | DIRECT |
PA domain | 0 | DIRECT |
(Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
Trimeric LpxA-like enzymes | 0 | DIRECT |
Cytochrome P450 | 0 | DIRECT |
ClpP/crotonase | 0 | DIRECT |
Glutamine synthetase/guanido kinase | 0 | DIRECT |
Acid proteases | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
GTPase activation domain, GAP | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
VPS9 domain | 0 | DIRECT |
Ribosomal protein L14 | 0 | DIRECT |
GYF domain | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
LeuD/IlvD-like | 0 | DIRECT |
Thiolase-like | 0 | DIRECT |
Ubiquitin-like | 0 | DIRECT |
EF-G C-terminal domain-like | 0 | DIRECT |
DNA repair protein MutS, domain II | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
Ras GEF | 0 | DIRECT |
Ribosomal protein S8 | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
HMG-box | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
Prefoldin | 0 | DIRECT |
DPP6 N-terminal domain-like | 0 | DIRECT |
beta-beta-alpha zinc fingers | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
Actin depolymerizing proteins | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
F-box domain | 0 | DIRECT |
MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
Galactose-binding domain-like | 0 | DIRECT |
Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
FAD-binding/transporter-associated domain-like | 0 | DIRECT |
Nop domain | 0 | DIRECT |
Subtilisin-like | 0 | DIRECT |
Transferrin receptor-like dimerisation domain | 0 | DIRECT |
PriA/YqbF domain | 0 | DIRECT |
Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
Pseudouridine synthase | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
Nucleotidyltransferase | 0 | DIRECT |
Zinc beta-ribbon | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
Metallo-dependent hydrolases | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
RNI-like | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
Ammonium transporter | 0 | DIRECT |
Mss4-like | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Methylglyoxal synthase-like | 0 | DIRECT |
Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
CorA soluble domain-like | 0 | DIRECT |
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
post-HMGL domain-like | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
Tubulin nucleotide-binding domain-like | 0 | DIRECT |
Magnesium transport protein CorA, transmembrane region | 0 | DIRECT |
CheY-like | 0 | DIRECT |
post-AAA+ oligomerization domain-like | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
Phospholipase D/nuclease | 0 | DIRECT |
DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
Galactose mutarotase-like | 0 | DIRECT |
Creatinase/prolidase N-terminal domain | 0 | DIRECT |
4'-phosphopantetheinyl transferase | 0 | DIRECT |
AMPKBI-like | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
L domain-like | 0 | DIRECT |
SpoIIaa-like | 0 | DIRECT |
Nudix | 0 | DIRECT |
RmlC-like cupins | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
PR-1-like | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
Family A G protein-coupled receptor-like | 0 | DIRECT |
Ribosomal protein L13 | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
GAT-like domain | 0 | DIRECT |
SRF-like | 0 | DIRECT |
Cytochrome c | 0 | DIRECT |
C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
Mitochondrial cytochrome c oxidase subunit IV | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Sialidases | 0 | DIRECT |
Ribosomal protein L6 | 0 | DIRECT |
Alpha-L RNA-binding motif | 0 | DIRECT |
PH domain-like | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
PLC-like phosphodiesterases | 0 | DIRECT |
Six-hairpin glycosidases | 0 | DIRECT |
SCOP term | FDR (all) | Annotation (direct or inherited) |
Ankyrin repeat | 0 | Direct |
FAD-linked oxidoreductase | 0 | Direct |
FMN-linked oxidoreductases | 0 | Direct |
RBP11-like subunits of RNA polymerase | 0 | Direct |
Heme oxygenase-like | 0 | Direct |
Cyclophilin-like | 0 | Direct |
TGS-like | 0 | Direct |
YjgF-like | 0 | Direct |
Fumarate reductase respiratory complex transmembrane subunits | 0 | Direct |
HIT-like | 0 | Direct |
SH3-domain | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
Ferritin-like | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
F1F0 ATP synthase subunit C | 0 | Direct |
Cullin repeat-like | 0 | Direct |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
Ribosomal protein L22 | 0 | Direct |
The spindle assembly checkpoint protein mad2 | 0 | Direct |
Ribosomal protein L30p/L7e | 0 | Direct |
eIF1-like | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
S13-like H2TH domain | 0 | Direct |
Nucleoporin domain | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
Cation efflux protein transmembrane domain-like | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
Restriction endonuclease-like | 0 | Direct |
KA1-like | 0 | Direct |
Radical SAM enzymes | 0 | Direct |
ThrRS/AlaRS common domain | 0 | Direct |
Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
YAP1 redox domain | 0 | Direct |
Rhomboid-like | 0 | Direct |
EPT/RTPC-like | 0 | Direct |
Phosphoglycerate mutase-like | 0 | Direct |
PEBP-like | 0 | Direct |
Concanavalin A-like lectins/glucanases | 0 | Direct |
Metallo-dependent phosphatases | 0 | Direct |
HRDC-like | 0 | Direct |
NagB/RpiA/CoA transferase-like | 0 | Direct |
Cullin homology domain | 0 | Direct |
GST C-terminal domain-like | 0 | Direct |
FMN-binding split barrel | 0 | Direct |
Carbohydrate phosphatase | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
L-aspartase-like | 0 | Direct |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
Seven-hairpin glycosidases | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
DNase I-like | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
Aldolase | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
Chromo domain-like | 0 | Direct |
LDH C-terminal domain-like | 0 | Direct |
Carbamate kinase-like | 0 | Direct |
ACT-like | 0 | Direct |
FAD-linked oxidases, C-terminal domain | 0 | Direct |
R3H domain | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Translational machinery components | 0 | Direct |
E set domains | 0 | Direct |
SAP domain | 0 | Direct |
Citrate synthase | 0 | Direct |
Phosphoglucomutase, C-terminal domain | 0 | Direct |
PLP-binding barrel | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
Nucleotide-binding domain | 0 | Direct |
Rudiment single hybrid motif | 0 | Direct |
Protein prenylyltransferase | 0 | Direct |
GINS helical bundle-like | 0 | Direct |
LexA/Signal peptidase | 0 | Direct |
PX domain | 0 | Direct |
ALDH-like | 0 | Direct |
GHMP Kinase, C-terminal domain | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
WW domain | 0 | Direct |
PP2C-like | 0 | Direct |
DNA-glycosylase | 0 | Direct |
Aconitase iron-sulfur domain | 0 | Direct |
FKBP-like | 0 | Direct |
Cupredoxins | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
Endosomal sorting complex assembly domain | 0 | Direct |
Phosphoglucomutase, first 3 domains | 0 | Direct |
Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
HMA, heavy metal-associated domain | 0 | Direct |
DNA repair protein MutS, domain I | 0 | Direct |
Amidase signature (AS) enzymes | 0 | Direct |
PA domain | 0 | Direct |
(Phosphotyrosine protein) phosphatases II | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
Trimeric LpxA-like enzymes | 0 | Direct |
Cytochrome P450 | 0 | Direct |
ClpP/crotonase | 0 | Direct |
Glutamine synthetase/guanido kinase | 0 | Direct |
Acid proteases | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
GTPase activation domain, GAP | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
VPS9 domain | 0 | Direct |
Ribosomal protein L14 | 0 | Direct |
GYF domain | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
PIN domain-like | 0 | Direct |
LeuD/IlvD-like | 0 | Direct |
Thiolase-like | 0 | Direct |
Ubiquitin-like | 0 | Direct |
EF-G C-terminal domain-like | 0 | Direct |
DNA repair protein MutS, domain II | 0 | Direct |
Kelch motif | 0 | Direct |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
Ras GEF | 0 | Direct |
Ribosomal protein S8 | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
HMG-box | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
Prefoldin | 0 | Direct |
DPP6 N-terminal domain-like | 0 | Direct |
beta-beta-alpha zinc fingers | 0 | Direct |
CCCH zinc finger | 0 | Direct |
Actin depolymerizing proteins | 0 | Direct |
Ribokinase-like | 0 | Direct |
F-box domain | 0 | Direct |
MurD-like peptide ligases, catalytic domain | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
Galactose-binding domain-like | 0 | Direct |
Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
FAD-binding/transporter-associated domain-like | 0 | Direct |
Nop domain | 0 | Direct |
Subtilisin-like | 0 | Direct |
Transferrin receptor-like dimerisation domain | 0 | Direct |
PriA/YqbF domain | 0 | Direct |
Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
NAD kinase/diacylglycerol kinase-like | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
Pseudouridine synthase | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
Nucleotidyltransferase | 0 | Direct |
Zinc beta-ribbon | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
Metallo-dependent hydrolases | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
RNI-like | 0 | Direct |
Aquaporin-like | 0 | Direct |
Multidrug resistance efflux transporter EmrE | 0 | Direct |
Ammonium transporter | 0 | Direct |
Mss4-like | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Methylglyoxal synthase-like | 0 | Direct |
Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
CorA soluble domain-like | 0 | Direct |
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | Direct |
Smc hinge domain | 0 | Direct |
t-snare proteins | 0 | Direct |
post-HMGL domain-like | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
Tubulin nucleotide-binding domain-like | 0 | Direct |
Magnesium transport protein CorA, transmembrane region | 0 | Direct |
CheY-like | 0 | Direct |
post-AAA+ oligomerization domain-like | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
Phospholipase D/nuclease | 0 | Direct |
DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
HSP40/DnaJ peptide-binding domain | 0 | Direct |
Galactose mutarotase-like | 0 | Direct |
Creatinase/prolidase N-terminal domain | 0 | Direct |
4'-phosphopantetheinyl transferase | 0 | Direct |
AMPKBI-like | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
L domain-like | 0 | Direct |
SpoIIaa-like | 0 | Direct |
Nudix | 0 | Direct |
RmlC-like cupins | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
PR-1-like | 0 | Direct |
Sec63 N-terminal domain-like | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
Family A G protein-coupled receptor-like | 0 | Direct |
Ribosomal protein L13 | 0 | Direct |
Single hybrid motif | 0 | Direct |
GAT-like domain | 0 | Direct |
SRF-like | 0 | Direct |
Cytochrome c | 0 | Direct |
C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
Mitochondrial cytochrome c oxidase subunit IV | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
Sialidases | 0 | Direct |
Ribosomal protein L6 | 0 | Direct |
Alpha-L RNA-binding motif | 0 | Direct |
PH domain-like | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
PLC-like phosphodiesterases | 0 | Direct |
Six-hairpin glycosidases | 0 | Direct |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this YP term (Not in SDYP)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
eIF1-like | 0 | DIRECT |
MIF4G domain-like | 0 | DIRECT |
DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | DIRECT |
N-acetyl transferase, NAT | 0 | DIRECT |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
Erythroid transcription factor GATA-1 | 0 | DIRECT |
PyrH-like | 0 | DIRECT |
TRAPP components | 0 | DIRECT |
RecA protein-like (ATPase-domain) | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
Glucose 6-phosphate dehydrogenase-like | 0 | DIRECT |
AMPKBI-like | 0 | DIRECT |
FAD-linked oxidases, N-terminal domain | 0 | DIRECT |
beta-glycanases | 0 | DIRECT |
Transcriptional factor domain | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
FKBP immunophilin/proline isomerase | 0 | DIRECT |
Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
Serine carboxypeptidase-like | 0 | DIRECT |
Aminoacid dehydrogenases | 0 | DIRECT |
Ferredoxin reductase FAD-binding domain-like | 0 | DIRECT |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
5' to 3' exonuclease catalytic domain | 0 | DIRECT |
FCH domain | 0 | DIRECT |
Aconitase iron-sulfur domain | 0 | DIRECT |
Cofilin-like | 0 | DIRECT |
HCP-like | 0 | DIRECT |
TENA/THI-4 | 0 | DIRECT |
Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
Glutathione peroxidase-like | 0 | DIRECT |
Cation efflux protein transmembrane domain-like | 0 | DIRECT |
LDH N-terminal domain-like | 0 | DIRECT |
Hexokinase | 0 | DIRECT |
RNA-polymerase beta-prime | 0 | DIRECT |
RNB domain-like | 0 | DIRECT |
Glycosyl hydrolases family 16 | 0 | DIRECT |
Amidase signature (AS) enzymes | 0 | DIRECT |
Heat-shock transcription factor | 0 | DIRECT |
Glycolipid 2-alpha-mannosyltransferase | 0 | DIRECT |
Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
BC ATP-binding domain-like | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
NagB-like | 0 | DIRECT |
SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
CheY-related | 0 | DIRECT |
Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
HMGL-like | 0 | DIRECT |
p120GAP domain-like | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
Adenosine/AMP deaminase | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Pseudouridine synthase I TruA | 0 | DIRECT |
Crotonase-like | 0 | DIRECT |
FMN-linked oxidoreductases | 0 | DIRECT |
Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Ribosomal protein S8 | 0 | DIRECT |
Lysophospholipase | 0 | DIRECT |
RING finger domain, C3HC4 | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
Subtilase propeptides/inhibitors | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
Multidomain cupredoxins | 0 | DIRECT |
DNA gyrase/MutL, N-terminal domain | 0 | DIRECT |
Cyclin | 0 | DIRECT |
Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
Thiamin biosynthesis kinases | 0 | DIRECT |
Class I aldolase | 0 | DIRECT |
PA domain | 0 | DIRECT |
Tetratricopeptide repeat (TPR) | 0 | DIRECT |
NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | DIRECT |
DNA polymerase I | 0 | DIRECT |
FabD-like | 0 | DIRECT |
Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
Ribosomal protein L14 | 0 | DIRECT |
NADPH-cytochrome p450 reductase-like | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
Ankyrin repeat | 0 | DIRECT |
Clathrin coat assembly domain | 0 | DIRECT |
VHS domain | 0 | DIRECT |
DNA repair protein MutS, domain I | 0 | DIRECT |
C-terminal domain of ribosomal protein L2 | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
IF2B-like | 0 | DIRECT |
Classic zinc finger, C2H2 | 0 | DIRECT |
VPS9 domain | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Glutathione S-transferase (GST), N-terminal domain | 0 | DIRECT |
Phosphoglucomutase, first 3 domains | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
SAP domain | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
Dual specificity phosphatase-like | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
Cofactor-dependent phosphoglycerate mutase | 0 | DIRECT |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Cyclophilin (peptidylprolyl isomerase) | 0 | DIRECT |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
Eps15 homology domain (EH domain) | 0 | DIRECT |
Ribosomal protein L6 | 0 | DIRECT |
Cytochrome P450 | 0 | DIRECT |
HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
Single strand DNA-binding domain, SSB | 0 | DIRECT |
Subtilases | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
Cytochrome p450 reductase N-terminal domain-like | 0 | DIRECT |
CorA soluble domain-like | 0 | DIRECT |
Magnesium transport protein CorA, transmembrane region | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
Trehalose-6-phosphate synthase, OtsA | 0 | DIRECT |
Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
PR-1-like | 0 | DIRECT |
Prefoldin | 0 | DIRECT |
TBP-associated factors, TAFs | 0 | DIRECT |
Cytochrome b5 | 0 | DIRECT |
Leukotriene A4 hydrolase catalytic domain | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
YjgF/L-PSP | 0 | DIRECT |
BC N-terminal domain-like | 0 | DIRECT |
Ribosomal protein L13 | 0 | DIRECT |
PDI-like | 0 | DIRECT |
Ribosomal protein S13 | 0 | DIRECT |
Ammonium transporter | 0 | DIRECT |
Ribosomal protein L30p/L7e | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Ubiquitin-related | 0 | DIRECT |
Histidine acid phosphatase | 0 | DIRECT |
Bacteriorhodopsin-like | 0 | DIRECT |
F1F0 ATP synthase subunit C | 0 | DIRECT |
AMPK-beta glycogen binding domain-like | 0 | DIRECT |
Formate/glycerate dehydrogenases, substrate-binding domain | 0 | DIRECT |
DNA gyrase/MutL, second domain | 0 | DIRECT |
C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
AAT-like | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
GHMP Kinase, N-terminal domain | 0 | DIRECT |
HMA, heavy metal-associated domain | 0 | DIRECT |
Clathrin adaptor core protein | 0 | DIRECT |
La domain | 0 | DIRECT |
SWIRM domain | 0 | DIRECT |
Myb/SANT domain | 0 | DIRECT |
XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
Transferrin receptor-like dimerisation domain | 0 | DIRECT |
Folylpolyglutamate synthetase | 0 | DIRECT |
DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
NAD kinase-like | 0 | DIRECT |
F-box domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
L-aspartase/fumarase | 0 | DIRECT |
Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
PP2C-like | 0 | DIRECT |
Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | DIRECT |
Thiolase-related | 0 | DIRECT |
tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | DIRECT |
WW domain | 0 | DIRECT |
DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
PX domain | 0 | DIRECT |
HMG-box | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
Ribosomal protein S4 | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
UBA domain | 0 | DIRECT |
Pseudouridine synthase RsuA/RluD | 0 | DIRECT |
Protein serine/threonine phosphatase | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
ENTH domain | 0 | DIRECT |
Forkhead DNA-binding domain | 0 | DIRECT |
GAPDH-like | 0 | DIRECT |
EF-G/eEF-2 domains III and V | 0 | DIRECT |
GYF domain | 0 | DIRECT |
Vacuolar sorting protein domain | 0 | DIRECT |
Glutathione S-transferase (GST), C-terminal domain | 0 | DIRECT |
Ribosomal protein L18 and S11 | 0 | DIRECT |
Ras GEF | 0 | DIRECT |
Glycosyl transferases group 1 | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
Tryptophan biosynthesis enzymes | 0 | DIRECT |
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Lactate & malate dehydrogenases, C-terminal domain | 0 | DIRECT |
YAP1 redox domain | 0 | DIRECT |
Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
FAD-linked reductases, N-terminal domain | 0 | DIRECT |
LeuD-like | 0 | DIRECT |
BCR-homology GTPase activation domain (BH-domain) | 0 | DIRECT |
SRF-like | 0 | DIRECT |
Ran-binding domain | 0 | DIRECT |
Ribosomal protein L22 | 0 | DIRECT |
Nucleosome core histones | 0 | DIRECT |
Phosphate binding protein-like | 0 | DIRECT |
Pepsin-like | 0 | DIRECT |
Choline/Carnitine O-acyltransferase | 0 | DIRECT |
Deoxycytidylate deaminase-like | 0 | DIRECT |
BC C-terminal domain-like | 0 | DIRECT |
Reductases | 0 | DIRECT |
NLI interacting factor-like phosphatase | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
Gastric lipase | 0 | DIRECT |
RuBisCo LSMT catalytic domain | 0 | DIRECT |
SCOP term | FDR (all) | Annotation (direct or inherited) |
eIF1-like | 0 | Direct |
MIF4G domain-like | 0 | Direct |
DNA ligase/mRNA capping enzyme postcatalytic domain | 0 | Direct |
N-acetyl transferase, NAT | 0 | Direct |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
Erythroid transcription factor GATA-1 | 0 | Direct |
PyrH-like | 0 | Direct |
TRAPP components | 0 | Direct |
RecA protein-like (ATPase-domain) | 0 | Direct |
Citrate synthase | 0 | Direct |
Glucose 6-phosphate dehydrogenase-like | 0 | Direct |
AMPKBI-like | 0 | Direct |
FAD-linked oxidases, N-terminal domain | 0 | Direct |
beta-glycanases | 0 | Direct |
Transcriptional factor domain | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
FKBP immunophilin/proline isomerase | 0 | Direct |
Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
Serine carboxypeptidase-like | 0 | Direct |
Aminoacid dehydrogenases | 0 | Direct |
Ferredoxin reductase FAD-binding domain-like | 0 | Direct |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
5' to 3' exonuclease catalytic domain | 0 | Direct |
FCH domain | 0 | Direct |
Aconitase iron-sulfur domain | 0 | Direct |
Cofilin-like | 0 | Direct |
HCP-like | 0 | Direct |
TENA/THI-4 | 0 | Direct |
Class I glutamine amidotransferases (GAT) | 0 | Direct |
Glutathione peroxidase-like | 0 | Direct |
Cation efflux protein transmembrane domain-like | 0 | Direct |
LDH N-terminal domain-like | 0 | Direct |
Hexokinase | 0 | Direct |
RNA-polymerase beta-prime | 0 | Direct |
RNB domain-like | 0 | Direct |
Glycosyl hydrolases family 16 | 0 | Direct |
Amidase signature (AS) enzymes | 0 | Direct |
Heat-shock transcription factor | 0 | Direct |
Glycolipid 2-alpha-mannosyltransferase | 0 | Direct |
Pleckstrin-homology domain (PH domain) | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
BC ATP-binding domain-like | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
NagB-like | 0 | Direct |
SCF ubiquitin ligase complex WHB domain | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
CheY-related | 0 | Direct |
Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
HMGL-like | 0 | Direct |
p120GAP domain-like | 0 | Direct |
Smc hinge domain | 0 | Direct |
Adenosine/AMP deaminase | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Pseudouridine synthase I TruA | 0 | Direct |
Crotonase-like | 0 | Direct |
FMN-linked oxidoreductases | 0 | Direct |
Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
Translational machinery components | 0 | Direct |
Ribosomal protein S8 | 0 | Direct |
Lysophospholipase | 0 | Direct |
RING finger domain, C3HC4 | 0 | Direct |
CCCH zinc finger | 0 | Direct |
Subtilase propeptides/inhibitors | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
Multidomain cupredoxins | 0 | Direct |
DNA gyrase/MutL, N-terminal domain | 0 | Direct |
Cyclin | 0 | Direct |
Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
Thiamin biosynthesis kinases | 0 | Direct |
Class I aldolase | 0 | Direct |
PA domain | 0 | Direct |
Tetratricopeptide repeat (TPR) | 0 | Direct |
NADPH-cytochrome p450 reductase FAD-binding domain-like | 0 | Direct |
DNA polymerase I | 0 | Direct |
FabD-like | 0 | Direct |
Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
Ribosomal protein L14 | 0 | Direct |
NADPH-cytochrome p450 reductase-like | 0 | Direct |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
Ankyrin repeat | 0 | Direct |
Clathrin coat assembly domain | 0 | Direct |
VHS domain | 0 | Direct |
DNA repair protein MutS, domain I | 0 | Direct |
C-terminal domain of ribosomal protein L2 | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
IF2B-like | 0 | Direct |
Classic zinc finger, C2H2 | 0 | Direct |
VPS9 domain | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Glutathione S-transferase (GST), N-terminal domain | 0 | Direct |
Phosphoglucomutase, first 3 domains | 0 | Direct |
SH3-domain | 0 | Direct |
SAP domain | 0 | Direct |
t-snare proteins | 0 | Direct |
Aquaporin-like | 0 | Direct |
Dual specificity phosphatase-like | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
Cofactor-dependent phosphoglycerate mutase | 0 | Direct |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Cyclophilin (peptidylprolyl isomerase) | 0 | Direct |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
Eps15 homology domain (EH domain) | 0 | Direct |
Ribosomal protein L6 | 0 | Direct |
Cytochrome P450 | 0 | Direct |
HSP40/DnaJ peptide-binding domain | 0 | Direct |
Single strand DNA-binding domain, SSB | 0 | Direct |
Subtilases | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
Cytochrome p450 reductase N-terminal domain-like | 0 | Direct |
CorA soluble domain-like | 0 | Direct |
Magnesium transport protein CorA, transmembrane region | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 0 | Direct |
Trehalose-6-phosphate synthase, OtsA | 0 | Direct |
Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
Ubiquitin activating enzymes (UBA) | 0 | Direct |
PR-1-like | 0 | Direct |
Prefoldin | 0 | Direct |
TBP-associated factors, TAFs | 0 | Direct |
Cytochrome b5 | 0 | Direct |
Leukotriene A4 hydrolase catalytic domain | 0 | Direct |
Chaperone J-domain | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
YjgF/L-PSP | 0 | Direct |
BC N-terminal domain-like | 0 | Direct |
Ribosomal protein L13 | 0 | Direct |
PDI-like | 0 | Direct |
Ribosomal protein S13 | 0 | Direct |
Ammonium transporter | 0 | Direct |
Ribosomal protein L30p/L7e | 0 | Direct |
Ribokinase-like | 0 | Direct |
Ubiquitin-related | 0 | Direct |
Histidine acid phosphatase | 0 | Direct |
Bacteriorhodopsin-like | 0 | Direct |
F1F0 ATP synthase subunit C | 0 | Direct |
AMPK-beta glycogen binding domain-like | 0 | Direct |
Formate/glycerate dehydrogenases, substrate-binding domain | 0 | Direct |
DNA gyrase/MutL, second domain | 0 | Direct |
C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
AAT-like | 0 | Direct |
ALDH-like | 0 | Direct |
GHMP Kinase, N-terminal domain | 0 | Direct |
HMA, heavy metal-associated domain | 0 | Direct |
Clathrin adaptor core protein | 0 | Direct |
La domain | 0 | Direct |
SWIRM domain | 0 | Direct |
Myb/SANT domain | 0 | Direct |
XPF/Rad1/Mus81 nuclease | 0 | Direct |
Transferrin receptor-like dimerisation domain | 0 | Direct |
Folylpolyglutamate synthetase | 0 | Direct |
DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
NAD kinase-like | 0 | Direct |
F-box domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
L-aspartase/fumarase | 0 | Direct |
Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
PP2C-like | 0 | Direct |
Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | Direct |
Thiolase-related | 0 | Direct |
tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | Direct |
WW domain | 0 | Direct |
DnaQ-like 3'-5' exonuclease | 0 | Direct |
DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
PX domain | 0 | Direct |
HMG-box | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
Phosphoglucomutase, C-terminal domain | 0 | Direct |
Ribosomal protein S4 | 0 | Direct |
Cullin homology domain | 0 | Direct |
UBA domain | 0 | Direct |
Pseudouridine synthase RsuA/RluD | 0 | Direct |
Protein serine/threonine phosphatase | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
Phosphoribulokinase/pantothenate kinase | 0 | Direct |
ENTH domain | 0 | Direct |
Forkhead DNA-binding domain | 0 | Direct |
GAPDH-like | 0 | Direct |
EF-G/eEF-2 domains III and V | 0 | Direct |
GYF domain | 0 | Direct |
Vacuolar sorting protein domain | 0 | Direct |
Glutathione S-transferase (GST), C-terminal domain | 0 | Direct |
Ribosomal protein L18 and S11 | 0 | Direct |
Ras GEF | 0 | Direct |
Glycosyl transferases group 1 | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
Tryptophan biosynthesis enzymes | 0 | Direct |
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Lactate & malate dehydrogenases, C-terminal domain | 0 | Direct |
YAP1 redox domain | 0 | Direct |
Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
FAD-linked reductases, N-terminal domain | 0 | Direct |
LeuD-like | 0 | Direct |
BCR-homology GTPase activation domain (BH-domain) | 0 | Direct |
SRF-like | 0 | Direct |
Ran-binding domain | 0 | Direct |
Ribosomal protein L22 | 0 | Direct |
Nucleosome core histones | 0 | Direct |
Phosphate binding protein-like | 0 | Direct |
Pepsin-like | 0 | Direct |
Choline/Carnitine O-acyltransferase | 0 | Direct |
Deoxycytidylate deaminase-like | 0 | Direct |
BC C-terminal domain-like | 0 | Direct |
Reductases | 0 | Direct |
NLI interacting factor-like phosphatase | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
Gastric lipase | 0 | Direct |
RuBisCo LSMT catalytic domain | 0 | Direct |
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A presence/absence matrix is generated using protein domain
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if individual trees had been produced. However, this data is extracted from the single
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this YP term (Not in SPYP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Pseudouridine synthase | 0 | DIRECT |
EPT/RTPC-like | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
Phosphoglycerate mutase-like | 0 | DIRECT |
Ligand-binding domain in the NO signalling and Golgi transport | 0 | DIRECT |
Galactose mutarotase-like | 0 | DIRECT |
Sialidases | 0 | DIRECT |
LDH C-terminal domain-like | 0 | DIRECT |
GST C-terminal domain-like | 0 | DIRECT |
Magnesium transport protein CorA, transmembrane region | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
WW domain | 0 | DIRECT |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
ThrRS/AlaRS common domain | 0 | DIRECT |
HIT-like | 0 | DIRECT |
S13-like H2TH domain | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
PR-1-like | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Concanavalin A-like lectins/glucanases | 0 | DIRECT |
SpoIIaa-like | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
The spindle assembly checkpoint protein mad2 | 0 | DIRECT |
PP2C-like | 0 | DIRECT |
Zinc beta-ribbon | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
FAD-binding/transporter-associated domain-like | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
Cupredoxins | 0 | DIRECT |
Cytochrome c | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | DIRECT |
HRDC-like | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
Ribosomal protein L30p/L7e | 0 | DIRECT |
Phospholipase D/nuclease | 0 | DIRECT |
Carbohydrate phosphatase | 0 | DIRECT |
DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
GHMP Kinase, C-terminal domain | 0 | DIRECT |
Metallo-dependent hydrolases | 0 | DIRECT |
KA1-like | 0 | DIRECT |
CheY-like | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Ribokinase-like | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
DNA repair protein MutS, domain II | 0 | DIRECT |
Aconitase iron-sulfur domain | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
Amidase signature (AS) enzymes | 0 | DIRECT |
eIF1-like | 0 | DIRECT |
LexA/Signal peptidase | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
MurD-like peptide ligases, catalytic domain | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
Nucleotide-binding domain | 0 | DIRECT |
beta-beta-alpha zinc fingers | 0 | DIRECT |
YAP1 redox domain | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
EF-G C-terminal domain-like | 0 | DIRECT |
Seven-hairpin glycosidases | 0 | DIRECT |
ClpP/crotonase | 0 | DIRECT |
Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
Phosphoglucomutase, first 3 domains | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
HMA, heavy metal-associated domain | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Alpha-L RNA-binding motif | 0 | DIRECT |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
YjgF-like | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
L domain-like | 0 | DIRECT |
DNA repair protein MutS, domain III | 0 | DIRECT |
RBP11-like subunits of RNA polymerase | 0 | DIRECT |
Nop domain | 0 | DIRECT |
SAP domain | 0 | DIRECT |
RNI-like | 0 | DIRECT |
L-aspartase-like | 0 | DIRECT |
Protein prenylyltransferase | 0 | DIRECT |
PH domain-like | 0 | DIRECT |
HMG-box | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
Zinc domain conserved in yeast copper-regulated transcription factors | 0 | DIRECT |
Tubulin nucleotide-binding domain-like | 0 | DIRECT |
C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
(Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
Heme oxygenase-like | 0 | DIRECT |
Acid proteases | 0 | DIRECT |
4'-phosphopantetheinyl transferase | 0 | DIRECT |
Rudiment single hybrid motif | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
FMN-binding split barrel | 0 | DIRECT |
Endosomal sorting complex assembly domain | 0 | DIRECT |
LeuD/IlvD-like | 0 | DIRECT |
PLC-like phosphodiesterases | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
VPS9 domain | 0 | DIRECT |
Ribosomal protein L6 | 0 | DIRECT |
DNA repair protein MutS, domain I | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
DNA-glycosylase | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
SRF-like | 0 | DIRECT |
PA domain | 0 | DIRECT |
GTPase activation domain, GAP | 0 | DIRECT |
Cytochrome P450 | 0 | DIRECT |
FMN-linked oxidoreductases | 0 | DIRECT |
GAT-like domain | 0 | DIRECT |
Nudix | 0 | DIRECT |
Mss4-like | 0 | DIRECT |
Nucleotidyltransferase | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
DPP6 N-terminal domain-like | 0 | DIRECT |
Thiolase-like | 0 | DIRECT |
Ras GEF | 0 | DIRECT |
Transferrin receptor-like dimerisation domain | 0 | DIRECT |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | DIRECT |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
AMPKBI-like | 0 | DIRECT |
Ankyrin repeat | 0 | DIRECT |
GYF domain | 0 | DIRECT |
FKBP-like | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
Ribosomal protein L13 | 0 | DIRECT |
Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
Fumarate reductase respiratory complex transmembrane subunits | 0 | DIRECT |
E set domains | 0 | DIRECT |
GINS helical bundle-like | 0 | DIRECT |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
Six-hairpin glycosidases | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
Citrate synthase | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
Mitochondrial cytochrome c oxidase subunit IV | 0 | DIRECT |
Nucleoporin domain | 0 | DIRECT |
Glutamine synthetase/guanido kinase | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Ubiquitin-like | 0 | DIRECT |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
Aldolase | 0 | DIRECT |
Creatinase/prolidase N-terminal domain | 0 | DIRECT |
RmlC-like cupins | 0 | DIRECT |
Ribosomal protein L14 | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
Carbamate kinase-like | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
Subtilisin-like | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Prefoldin | 0 | DIRECT |
post-AAA+ oligomerization domain-like | 0 | DIRECT |
PLP-binding barrel | 0 | DIRECT |
post-HMGL domain-like | 0 | DIRECT |
PEBP-like | 0 | DIRECT |
Ammonium transporter | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
Ribosomal protein S8 | 0 | DIRECT |
PriA/YqbF domain | 0 | DIRECT |
Cytochrome b5-like heme/steroid binding domain | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Actin depolymerizing proteins | 0 | DIRECT |
F-box domain | 0 | DIRECT |
FAD-linked oxidoreductase | 0 | DIRECT |
Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
PX domain | 0 | DIRECT |
Trimeric LpxA-like enzymes | 0 | DIRECT |
TGS-like | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
Cation efflux protein transmembrane domain-like | 0 | DIRECT |
CorA soluble domain-like | 0 | DIRECT |
Radical SAM enzymes | 0 | DIRECT |
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | DIRECT |
R3H domain | 0 | DIRECT |
NagB/RpiA/CoA transferase-like | 0 | DIRECT |
ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
Family A G protein-coupled receptor-like | 0 | DIRECT |
Ribosomal protein L22 | 0 | DIRECT |
HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
Galactose-binding domain-like | 0 | DIRECT |
tRNA-intron endonuclease catalytic domain-like | 0 | DIRECT |
Methylglyoxal synthase-like | 0 | DIRECT |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
ACT-like | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
F1F0 ATP synthase subunit C | 0 | DIRECT |
Cyclophilin-like | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Pseudouridine synthase | 0 | Direct |
EPT/RTPC-like | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
Phosphoglycerate mutase-like | 0 | Direct |
Ligand-binding domain in the NO signalling and Golgi transport | 0 | Direct |
Galactose mutarotase-like | 0 | Direct |
Sialidases | 0 | Direct |
LDH C-terminal domain-like | 0 | Direct |
GST C-terminal domain-like | 0 | Direct |
Magnesium transport protein CorA, transmembrane region | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Phosphoglucomutase, C-terminal domain | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
WW domain | 0 | Direct |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
ThrRS/AlaRS common domain | 0 | Direct |
HIT-like | 0 | Direct |
S13-like H2TH domain | 0 | Direct |
Aquaporin-like | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
PR-1-like | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Concanavalin A-like lectins/glucanases | 0 | Direct |
SpoIIaa-like | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
The spindle assembly checkpoint protein mad2 | 0 | Direct |
PP2C-like | 0 | Direct |
Zinc beta-ribbon | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
FAD-binding/transporter-associated domain-like | 0 | Direct |
PIN domain-like | 0 | Direct |
Cupredoxins | 0 | Direct |
Cytochrome c | 0 | Direct |
t-snare proteins | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
DNA-binding domain of Mlu1-box binding protein MBP1 | 0 | Direct |
HRDC-like | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
Ribosomal protein L30p/L7e | 0 | Direct |
Phospholipase D/nuclease | 0 | Direct |
Carbohydrate phosphatase | 0 | Direct |
DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
Cap-Gly domain | 0 | Direct |
GHMP Kinase, C-terminal domain | 0 | Direct |
Metallo-dependent hydrolases | 0 | Direct |
KA1-like | 0 | Direct |
CheY-like | 0 | Direct |
ALDH-like | 0 | Direct |
Ribokinase-like | 0 | Direct |
Sec63 N-terminal domain-like | 0 | Direct |
NAD kinase/diacylglycerol kinase-like | 0 | Direct |
DNA repair protein MutS, domain II | 0 | Direct |
Aconitase iron-sulfur domain | 0 | Direct |
Kelch motif | 0 | Direct |
Amidase signature (AS) enzymes | 0 | Direct |
eIF1-like | 0 | Direct |
LexA/Signal peptidase | 0 | Direct |
Cullin homology domain | 0 | Direct |
MurD-like peptide ligases, catalytic domain | 0 | Direct |
Smc hinge domain | 0 | Direct |
Nucleotide-binding domain | 0 | Direct |
beta-beta-alpha zinc fingers | 0 | Direct |
YAP1 redox domain | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
EF-G C-terminal domain-like | 0 | Direct |
Seven-hairpin glycosidases | 0 | Direct |
ClpP/crotonase | 0 | Direct |
Multidrug resistance efflux transporter EmrE | 0 | Direct |
Phosphoglucomutase, first 3 domains | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
HMA, heavy metal-associated domain | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Alpha-L RNA-binding motif | 0 | Direct |
DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
YjgF-like | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
L domain-like | 0 | Direct |
DNA repair protein MutS, domain III | 0 | Direct |
RBP11-like subunits of RNA polymerase | 0 | Direct |
Nop domain | 0 | Direct |
SAP domain | 0 | Direct |
RNI-like | 0 | Direct |
L-aspartase-like | 0 | Direct |
Protein prenylyltransferase | 0 | Direct |
PH domain-like | 0 | Direct |
HMG-box | 0 | Direct |
DNase I-like | 0 | Direct |
Zinc domain conserved in yeast copper-regulated transcription factors | 0 | Direct |
Tubulin nucleotide-binding domain-like | 0 | Direct |
C-terminal autoproteolytic domain of nucleoporin nup98 | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
(Phosphotyrosine protein) phosphatases II | 0 | Direct |
Heme oxygenase-like | 0 | Direct |
Acid proteases | 0 | Direct |
4'-phosphopantetheinyl transferase | 0 | Direct |
Rudiment single hybrid motif | 0 | Direct |
CCCH zinc finger | 0 | Direct |
Chromo domain-like | 0 | Direct |
FMN-binding split barrel | 0 | Direct |
Endosomal sorting complex assembly domain | 0 | Direct |
LeuD/IlvD-like | 0 | Direct |
PLC-like phosphodiesterases | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
Restriction endonuclease-like | 0 | Direct |
FAD-linked oxidases, C-terminal domain | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
Ferritin-like | 0 | Direct |
VPS9 domain | 0 | Direct |
Ribosomal protein L6 | 0 | Direct |
DNA repair protein MutS, domain I | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
DNA-glycosylase | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
SRF-like | 0 | Direct |
PA domain | 0 | Direct |
GTPase activation domain, GAP | 0 | Direct |
Cytochrome P450 | 0 | Direct |
FMN-linked oxidoreductases | 0 | Direct |
GAT-like domain | 0 | Direct |
Nudix | 0 | Direct |
Mss4-like | 0 | Direct |
Nucleotidyltransferase | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
SH3-domain | 0 | Direct |
DPP6 N-terminal domain-like | 0 | Direct |
Thiolase-like | 0 | Direct |
Ras GEF | 0 | Direct |
Transferrin receptor-like dimerisation domain | 0 | Direct |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 0 | Direct |
FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
AMPKBI-like | 0 | Direct |
Ankyrin repeat | 0 | Direct |
GYF domain | 0 | Direct |
FKBP-like | 0 | Direct |
Metallo-dependent phosphatases | 0 | Direct |
Ribosomal protein L13 | 0 | Direct |
Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
Fumarate reductase respiratory complex transmembrane subunits | 0 | Direct |
E set domains | 0 | Direct |
GINS helical bundle-like | 0 | Direct |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
Six-hairpin glycosidases | 0 | Direct |
Single hybrid motif | 0 | Direct |
Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
Citrate synthase | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
Cullin repeat-like | 0 | Direct |
Mitochondrial cytochrome c oxidase subunit IV | 0 | Direct |
Nucleoporin domain | 0 | Direct |
Glutamine synthetase/guanido kinase | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Ubiquitin-like | 0 | Direct |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
Aldolase | 0 | Direct |
Creatinase/prolidase N-terminal domain | 0 | Direct |
RmlC-like cupins | 0 | Direct |
Ribosomal protein L14 | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
Carbamate kinase-like | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
Subtilisin-like | 0 | Direct |
Translational machinery components | 0 | Direct |
Prefoldin | 0 | Direct |
post-AAA+ oligomerization domain-like | 0 | Direct |
PLP-binding barrel | 0 | Direct |
post-HMGL domain-like | 0 | Direct |
PEBP-like | 0 | Direct |
Ammonium transporter | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
Ribosomal protein S8 | 0 | Direct |
PriA/YqbF domain | 0 | Direct |
Cytochrome b5-like heme/steroid binding domain | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Actin depolymerizing proteins | 0 | Direct |
F-box domain | 0 | Direct |
FAD-linked oxidoreductase | 0 | Direct |
Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
PX domain | 0 | Direct |
Trimeric LpxA-like enzymes | 0 | Direct |
TGS-like | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
Cation efflux protein transmembrane domain-like | 0 | Direct |
CorA soluble domain-like | 0 | Direct |
Radical SAM enzymes | 0 | Direct |
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0 | Direct |
R3H domain | 0 | Direct |
NagB/RpiA/CoA transferase-like | 0 | Direct |
ValRS/IleRS/LeuRS editing domain | 0 | Direct |
Family A G protein-coupled receptor-like | 0 | Direct |
Ribosomal protein L22 | 0 | Direct |
HSP40/DnaJ peptide-binding domain | 0 | Direct |
Galactose-binding domain-like | 0 | Direct |
tRNA-intron endonuclease catalytic domain-like | 0 | Direct |
Methylglyoxal synthase-like | 0 | Direct |
Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
ACT-like | 0 | Direct |
Rhomboid-like | 0 | Direct |
F1F0 ATP synthase subunit C | 0 | Direct |
Cyclophilin-like | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
(show details)
Supra-domains annotated to this YP term (Not in SPYP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | DIRECT |
50677,52374 50677 - ValRS/IleRS/LeuRS editing domain 52374 - Nucleotidylyl transferase | 0 | DIRECT |
53756,56784 53756 - UDP-Glycosyltransferase/glycogen phosphorylase 56784 - HAD-like | 0 | DIRECT |
53901,53901 53901 - Thiolase-like 53901 - Thiolase-like | 0 | DIRECT |
51569,89000 51569 - Aldolase 89000 - post-HMGL domain-like | 0 | DIRECT |
90229,90229 90229 - CCCH zinc finger 90229 - CCCH zinc finger | 0 | DIRECT |
57850,52540 57850 - RING/U-box 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | DIRECT |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | DIRECT |
56024,56024 56024 - Phospholipase D/nuclease 56024 - Phospholipase D/nuclease | 0 | DIRECT |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
46689,46689 46689 - Homeodomain-like 46689 - Homeodomain-like | 0 | DIRECT |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
56235,52402 56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases) 52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | DIRECT |
63380,52343 63380 - Riboflavin synthase domain-like 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
56053,56053 56053 - Ribosomal protein L6 56053 - Ribosomal protein L6 | 0 | DIRECT |
54236,57829 54236 - Ubiquitin-like 57829 - Zn-binding ribosomal proteins | 0 | DIRECT |
49493,49493 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
51905,51905 51905 - FAD/NAD(P)-binding domain 51905 - FAD/NAD(P)-binding domain | 0 | DIRECT |
50615,52540 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56059,51246 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | DIRECT |
50249,50104 50249 - Nucleic acid-binding proteins 50104 - Translation proteins SH3-like domain | 0 | DIRECT |
47661,58038 47661 - t-snare proteins 58038 - SNARE fusion complex | 0 | DIRECT |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0 | DIRECT |
54980,54211 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
46565,57938 46565 - Chaperone J-domain 57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | DIRECT |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
48371,-7 48371 - ARM repeat -7 - CATH | 0 | DIRECT |
-9,-9 -9 - PDB -9 - PDB | 0 | DIRECT |
48464,89009 48464 - ENTH/VHS domain 89009 - GAT-like domain | 0 | DIRECT |
75632,46785 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
55874,54211 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
48334,52540 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
88723,47807 88723 - PIN domain-like 47807 - 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
53738,55957 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
47923,47923 47923 - Ypt/Rab-GAP domain of gyp1p 47923 - Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
54631,54631 54631 - CBS-domain pair 54631 - CBS-domain pair | 0 | DIRECT |
50447,54980 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
51905,56425 51905 - FAD/NAD(P)-binding domain 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | DIRECT |
56176,55103 56176 - FAD-binding/transporter-associated domain-like 55103 - FAD-linked oxidases, C-terminal domain | 0 | DIRECT |
57938,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
56091,50249 56091 - DNA ligase/mRNA capping enzyme, catalytic domain 50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | DIRECT |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
143865,144083 143865 - CorA soluble domain-like 144083 - Magnesium transport protein CorA, transmembrane region | 0 | DIRECT |
51735,56327 51735 - NAD(P)-binding Rossmann-fold domains 56327 - LDH C-terminal domain-like | 0 | DIRECT |
52540,48019 52540 - P-loop containing nucleoside triphosphate hydrolases 48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
51905,55424 51905 - FAD/NAD(P)-binding domain 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | DIRECT |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
53732,52016 53732 - Aconitase iron-sulfur domain 52016 - LeuD/IlvD-like | 0 | DIRECT |
52540,81271 52540 - P-loop containing nucleoside triphosphate hydrolases 81271 - TGS-like | 0 | DIRECT |
53223,51735 53223 - Aminoacid dehydrogenase-like, N-terminal domain 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | DIRECT |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | DIRECT |
49503,49503 49503 - Cupredoxins 49503 - Cupredoxins | 0 | DIRECT |
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C | 0 | DIRECT |
53098,56672 53098 - Ribonuclease H-like 56672 - DNA/RNA polymerases | 0 | DIRECT |
103657,50729 103657 - BAR/IMD domain-like 50729 - PH domain-like | 0 | DIRECT |
52025,53187 52025 - PA domain 53187 - Zn-dependent exopeptidases | 0 | DIRECT |
51735,55347 51735 - NAD(P)-binding Rossmann-fold domains 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
53187,47672 53187 - Zn-dependent exopeptidases 47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
54211,55060 54211 - Ribosomal protein S5 domain 2-like 55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
53150,48334 53150 - DNA repair protein MutS, domain II 48334 - DNA repair protein MutS, domain III | 0 | DIRECT |
53623,53244 53623 - MurD-like peptide ligases, catalytic domain 53244 - MurD-like peptide ligases, peptide-binding domain | 0 | DIRECT |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | DIRECT |
53613,48613 53613 - Ribokinase-like 48613 - Heme oxygenase-like | 0 | DIRECT |
54211,54980 54211 - Ribosomal protein S5 domain 2-like 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
103473,103473 103473 - MFS general substrate transporter 103473 - MFS general substrate transporter | 0 | DIRECT |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
52540,53254 52540 - P-loop containing nucleoside triphosphate hydrolases 53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | DIRECT |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
52833,52833 52833 - Thioredoxin-like 52833 - Thioredoxin-like | 0 | Direct |
50677,52374 50677 - ValRS/IleRS/LeuRS editing domain 52374 - Nucleotidylyl transferase | 0 | Direct |
53756,56784 53756 - UDP-Glycosyltransferase/glycogen phosphorylase 56784 - HAD-like | 0 | Direct |
53901,53901 53901 - Thiolase-like 53901 - Thiolase-like | 0 | Direct |
51569,89000 51569 - Aldolase 89000 - post-HMGL domain-like | 0 | Direct |
90229,90229 90229 - CCCH zinc finger 90229 - CCCH zinc finger | 0 | Direct |
57850,52540 57850 - RING/U-box 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | Direct |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | Direct |
56024,56024 56024 - Phospholipase D/nuclease 56024 - Phospholipase D/nuclease | 0 | Direct |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | Direct |
46689,46689 46689 - Homeodomain-like 46689 - Homeodomain-like | 0 | Direct |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
56235,52402 56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases) 52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | Direct |
63380,52343 63380 - Riboflavin synthase domain-like 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
56053,56053 56053 - Ribosomal protein L6 56053 - Ribosomal protein L6 | 0 | Direct |
54236,57829 54236 - Ubiquitin-like 57829 - Zn-binding ribosomal proteins | 0 | Direct |
49493,49493 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
51905,51905 51905 - FAD/NAD(P)-binding domain 51905 - FAD/NAD(P)-binding domain | 0 | Direct |
50615,52540 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56059,51246 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | Direct |
50249,50104 50249 - Nucleic acid-binding proteins 50104 - Translation proteins SH3-like domain | 0 | Direct |
47661,58038 47661 - t-snare proteins 58038 - SNARE fusion complex | 0 | Direct |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0 | Direct |
54980,54211 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0 | Direct |
53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
46565,57938 46565 - Chaperone J-domain 57938 - DnaJ/Hsp40 cysteine-rich domain | 0 | Direct |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
48371,-7 48371 - ARM repeat -7 - CATH | 0 | Direct |
-9,-9 -9 - PDB -9 - PDB | 0 | Direct |
48464,89009 48464 - ENTH/VHS domain 89009 - GAT-like domain | 0 | Direct |
75632,46785 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
55874,54211 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
48334,52540 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
88723,47807 88723 - PIN domain-like 47807 - 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
53738,55957 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
47923,47923 47923 - Ypt/Rab-GAP domain of gyp1p 47923 - Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
54631,54631 54631 - CBS-domain pair 54631 - CBS-domain pair | 0 | Direct |
50447,54980 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | Direct |
51905,56425 51905 - FAD/NAD(P)-binding domain 56425 - Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 0 | Direct |
56176,55103 56176 - FAD-binding/transporter-associated domain-like 55103 - FAD-linked oxidases, C-terminal domain | 0 | Direct |
57938,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
56091,50249 56091 - DNA ligase/mRNA capping enzyme, catalytic domain 50249 - Nucleic acid-binding proteins | 0 | Direct |
50249,50249 50249 - Nucleic acid-binding proteins 50249 - Nucleic acid-binding proteins | 0 | Direct |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
143865,144083 143865 - CorA soluble domain-like 144083 - Magnesium transport protein CorA, transmembrane region | 0 | Direct |
51735,56327 51735 - NAD(P)-binding Rossmann-fold domains 56327 - LDH C-terminal domain-like | 0 | Direct |
52540,48019 52540 - P-loop containing nucleoside triphosphate hydrolases 48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
51905,55424 51905 - FAD/NAD(P)-binding domain 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 0 | Direct |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
53732,52016 53732 - Aconitase iron-sulfur domain 52016 - LeuD/IlvD-like | 0 | Direct |
52540,81271 52540 - P-loop containing nucleoside triphosphate hydrolases 81271 - TGS-like | 0 | Direct |
53223,51735 53223 - Aminoacid dehydrogenase-like, N-terminal domain 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | Direct |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | Direct |
49503,49503 49503 - Cupredoxins 49503 - Cupredoxins | 0 | Direct |
81333,81333 81333 - F1F0 ATP synthase subunit C 81333 - F1F0 ATP synthase subunit C | 0 | Direct |
53098,56672 53098 - Ribonuclease H-like 56672 - DNA/RNA polymerases | 0 | Direct |
103657,50729 103657 - BAR/IMD domain-like 50729 - PH domain-like | 0 | Direct |
52025,53187 52025 - PA domain 53187 - Zn-dependent exopeptidases | 0 | Direct |
51735,55347 51735 - NAD(P)-binding Rossmann-fold domains 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
53187,47672 53187 - Zn-dependent exopeptidases 47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
54211,55060 54211 - Ribosomal protein S5 domain 2-like 55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
53150,48334 53150 - DNA repair protein MutS, domain II 48334 - DNA repair protein MutS, domain III | 0 | Direct |
53623,53244 53623 - MurD-like peptide ligases, catalytic domain 53244 - MurD-like peptide ligases, peptide-binding domain | 0 | Direct |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | Direct |
53613,48613 53613 - Ribokinase-like 48613 - Heme oxygenase-like | 0 | Direct |
54211,54980 54211 - Ribosomal protein S5 domain 2-like 54980 - EF-G C-terminal domain-like | 0 | Direct |
103473,103473 103473 - MFS general substrate transporter 103473 - MFS general substrate transporter | 0 | Direct |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
52540,53254 52540 - P-loop containing nucleoside triphosphate hydrolases 53254 - Phosphoglycerate mutase-like | 0 | Direct |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | Direct |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
(show details)
Supra-domains annotated to this YP term (Not in SPYP)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,54980,54211 50447 - Translation proteins 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
54980,54211,54980 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
46565,57938,49493 46565 - Chaperone J-domain 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
49562,49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57938,49493,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | DIRECT |
53150,48334,52540 53150 - DNA repair protein MutS, domain II 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
52540,50447,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
49503,49503,49503 49503 - Cupredoxins 49503 - Cupredoxins 49503 - Cupredoxins | 0 | DIRECT |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
57756,57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
53738,53738,55957 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | DIRECT |
52440,56059,51246 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | DIRECT |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50615,52540,47917 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
53738,53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | DIRECT |
52025,53187,47672 52025 - PA domain 53187 - Zn-dependent exopeptidases 47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,54980,54211 50447 - Translation proteins 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
54980,54211,54980 54980 - EF-G C-terminal domain-like 54211 - Ribosomal protein S5 domain 2-like 54980 - EF-G C-terminal domain-like | 0 | Direct |
46565,57938,49493 46565 - Chaperone J-domain 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
49562,49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57938,49493,49493 57938 - DnaJ/Hsp40 cysteine-rich domain 49493 - HSP40/DnaJ peptide-binding domain 49493 - HSP40/DnaJ peptide-binding domain | 0 | Direct |
53150,48334,52540 53150 - DNA repair protein MutS, domain II 48334 - DNA repair protein MutS, domain III 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
52540,50447,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | Direct |
49503,49503,49503 49503 - Cupredoxins 49503 - Cupredoxins 49503 - Cupredoxins | 0 | Direct |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
57756,57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0 | Direct |
53738,53738,55957 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 55957 - Phosphoglucomutase, C-terminal domain | 0 | Direct |
52440,56059,51246 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif | 0 | Direct |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50615,52540,47917 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
53738,53738,53738 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains 53738 - Phosphoglucomutase, first 3 domains | 0 | Direct |
52025,53187,47672 52025 - PA domain 53187 - Zn-dependent exopeptidases 47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
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