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Zebrafish Anatomy (ZA): whole organism
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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: ZA Hierarchy (zebrafish anatomy from ZFIN zebrafish anatomy ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this ZA term (Not in SDZA)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
DUSP-like | 0 | DIRECT |
Lipocalins | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
Trypsin-like serine proteases | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
PKD domain | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
F-box domain | 0 | DIRECT |
Interleukin 8-like chemokines | 0 | DIRECT |
Ubiquitin-like | 0 | DIRECT |
HIT-like | 0 | DIRECT |
ADP-ribosylation | 0 | DIRECT |
Serine protease inhibitors | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
C-type lectin-like | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Tudor/PWWP/MBT | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
Moesin tail domain | 0 | DIRECT |
ADC-like | 0 | DIRECT |
Connexin43 | 0 | DIRECT |
Troponin coil-coiled subunits | 0 | DIRECT |
TIMP-like | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
HD-domain/PDEase-like | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
Nucleic acid-binding proteins | 0 | DIRECT |
ARM repeat | 0 | DIRECT |
Tubulin nucleotide-binding domain-like | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Cysteine-rich domain | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
p53 tetramerization domain | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
Nucleoplasmin-like core domain | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
Translation proteins | 0 | DIRECT |
EF-hand | 0 | DIRECT |
IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
Caspase-like | 0 | DIRECT |
SAM/Pointed domain | 0 | DIRECT |
Subtilisin-like | 0 | DIRECT |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
Intermediate filament protein, coiled coil region | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
Phoshotransferase/anion transport protein | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
Cytokine | 0 | DIRECT |
Kazal-type serine protease inhibitors | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
p53-like transcription factors | 0 | DIRECT |
PLC-like phosphodiesterases | 0 | DIRECT |
Zinc beta-ribbon | 0 | DIRECT |
Protein kinase-like (PK-like) | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
Class II aaRS ABD-related | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
Tetraspanin | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
Histone-fold | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
ABC transporter transmembrane region | 0 | DIRECT |
Transcription factor STAT-4 N-domain | 0 | DIRECT |
Ribonuclease H-like | 0 | DIRECT |
Class II aaRS and biotin synthetases | 0 | DIRECT |
LDL receptor-like module | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
L27 domain | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
BRCT domain | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
Bet v1-like | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
PLP-dependent transferases | 0 | DIRECT |
PP2C-like | 0 | DIRECT |
GroES-like | 0 | DIRECT |
Acetyl-CoA synthetase-like | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Translation proteins SH3-like domain | 0 | DIRECT |
RNA-binding domain, RBD | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
GST C-terminal domain-like | 0 | DIRECT |
Ricin B-like lectins | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
L domain-like | 0 | DIRECT |
TNF receptor-like | 0 | DIRECT |
Plakin repeat | 0 | DIRECT |
CoA-dependent acyltransferases | 0 | DIRECT |
SMAD/FHA domain | 0 | DIRECT |
Hedgehog/intein (Hint) domain | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
GFP-like | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Homeodomain-like | 0 | DIRECT |
UBA-like | 0 | DIRECT |
Voltage-gated potassium channels | 0 | DIRECT |
"Winged helix" DNA-binding domain | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
Galactose-binding domain-like | 0 | DIRECT |
FnI-like domain | 0 | DIRECT |
CCHHC domain | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
TATA-box binding protein-like | 0 | DIRECT |
UBC-like | 0 | DIRECT |
DNA/RNA polymerases | 0 | DIRECT |
Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
SRF-like | 0 | DIRECT |
LCCL domain | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
HMG-box | 0 | DIRECT |
TPR-like | 0 | DIRECT |
Ribosomal protein S5 domain 2-like | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Kringle-like | 0 | DIRECT |
BRK domain-like | 0 | DIRECT |
PH domain-like | 0 | DIRECT |
PDZ domain-like | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
HAD-like | 0 | DIRECT |
Hemopexin-like domain | 0 | DIRECT |
Myosin rod fragments | 0 | DIRECT |
PGBD-like | 0 | DIRECT |
WW domain | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
ENTH/VHS domain | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Periplasmic binding protein-like I | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
Carbonic anhydrase | 0 | DIRECT |
Cupredoxins | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
Nuclear receptor ligand-binding domain | 0 | DIRECT |
FAD-linked reductases, C-terminal domain | 0 | DIRECT |
Periplasmic binding protein-like II | 0 | DIRECT |
JAB1/MPN domain | 0 | DIRECT |
G protein-binding domain | 0 | DIRECT |
Orange domain-like | 0 | DIRECT |
Integrin alpha N-terminal domain | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
TSP-1 type 1 repeat | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
ACT-like | 0 | DIRECT |
TNF-like | 0 | DIRECT |
BPTI-like | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
GLA-domain | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
SH2 domain | 0 | DIRECT |
Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
Cytochrome P450 | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
Nucleotidylyl transferase | 0 | DIRECT |
DPP6 N-terminal domain-like | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
Actin-like ATPase domain | 0 | DIRECT |
Polo-box domain | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
Metallo-dependent hydrolases | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
Nicotinic receptor ligand binding domain-like | 0 | DIRECT |
Aldolase | 0 | DIRECT |
4-helical cytokines | 0 | DIRECT |
SNARE-like | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
MFS general substrate transporter | 0 | DIRECT |
SET domain | 0 | DIRECT |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
beta-beta-alpha zinc fingers | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
PAZ domain | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
CalX-like | 0 | DIRECT |
Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
Hedgehog/DD-peptidase | 0 | DIRECT |
Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
EGF/Laminin | 0 | DIRECT |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
Insulin-like | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
(Trans)glycosidases | 0 | DIRECT |
vWA-like | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
alpha/beta-Hydrolases | 0 | DIRECT |
Leucine zipper domain | 0 | DIRECT |
STAT | 0 | DIRECT |
Snake toxin-like | 0 | DIRECT |
dsRNA-binding domain-like | 0 | DIRECT |
RuvA domain 2-like | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
Family A G protein-coupled receptor-like | 0 | DIRECT |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
PX domain | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
GTPase activation domain, GAP | 0 | DIRECT |
Sema domain | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
Nucleotide cyclase | 0 | DIRECT |
Zn-dependent exopeptidases | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
POZ domain | 0 | DIRECT |
Ras GEF | 0 | DIRECT |
Notch domain | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
Thioredoxin-like | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
FAS1 domain | 0 | DIRECT |
Heme-dependent peroxidases | 0 | DIRECT |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
E set domains | 0 | DIRECT |
DHS-like NAD/FAD-binding domain | 0 | DIRECT |
Cystine-knot cytokines | 0 | DIRECT |
HCP-like | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
Cyclin-like | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
(Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
MAPEG domain-like | 0 | DIRECT |
Cysteine proteinases | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
WD40 repeat-like | 0.8511 | INHERITED FROM: photoreceptor outer segment layer || retinal outer nuclear layer |
Immunoglobulin | 0.8511 | INHERITED FROM: white matter || olfactory bulb glomerulus || medial longitudinal fasciculus |
Fibronectin type III | 0.8986 | INHERITED FROM: white matter || synencephalon || medial longitudinal fasciculus || glomerular layer |
Concanavalin A-like lectins/glucanases | 0.9103 | INHERITED FROM: epidermis |
Ankyrin repeat | 0.9513 | INHERITED FROM: radial glial cell |
SCOP term | FDR (all) | Annotation (direct or inherited) |
DUSP-like | 0 | Direct |
Lipocalins | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
Trypsin-like serine proteases | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
Aquaporin-like | 0 | Direct |
PKD domain | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
F-box domain | 0 | Direct |
Interleukin 8-like chemokines | 0 | Direct |
Ubiquitin-like | 0 | Direct |
HIT-like | 0 | Direct |
ADP-ribosylation | 0 | Direct |
Serine protease inhibitors | 0 | Direct |
ALDH-like | 0 | Direct |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
Integrin domains | 0 | Direct |
C-type lectin-like | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Tudor/PWWP/MBT | 0 | Direct |
Smc hinge domain | 0 | Direct |
Moesin tail domain | 0 | Direct |
ADC-like | 0 | Direct |
Connexin43 | 0 | Direct |
Troponin coil-coiled subunits | 0 | Direct |
TIMP-like | 0 | Direct |
Cap-Gly domain | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
HD-domain/PDEase-like | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
Nucleic acid-binding proteins | 0 | Direct |
ARM repeat | 0 | Direct |
Tubulin nucleotide-binding domain-like | 0 | Direct |
YWTD domain | 0 | Direct |
Cysteine-rich domain | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
p53 tetramerization domain | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
Nucleoplasmin-like core domain | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
Cadherin-like | 0 | Direct |
Translation proteins | 0 | Direct |
EF-hand | 0 | Direct |
IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
Caspase-like | 0 | Direct |
SAM/Pointed domain | 0 | Direct |
Subtilisin-like | 0 | Direct |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
Intermediate filament protein, coiled coil region | 0 | Direct |
MIR domain | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
Phoshotransferase/anion transport protein | 0 | Direct |
Second domain of FERM | 0 | Direct |
Plexin repeat | 0 | Direct |
Cytokine | 0 | Direct |
Kazal-type serine protease inhibitors | 0 | Direct |
DEATH domain | 0 | Direct |
NAD(P)-binding Rossmann-fold domains | 0 | Direct |
Bromodomain | 0 | Direct |
p53-like transcription factors | 0 | Direct |
PLC-like phosphodiesterases | 0 | Direct |
Zinc beta-ribbon | 0 | Direct |
Protein kinase-like (PK-like) | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
Class II aaRS ABD-related | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
Tetraspanin | 0 | Direct |
Tropomyosin | 0 | Direct |
Histone-fold | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
ABC transporter transmembrane region | 0 | Direct |
Transcription factor STAT-4 N-domain | 0 | Direct |
Ribonuclease H-like | 0 | Direct |
Class II aaRS and biotin synthetases | 0 | Direct |
LDL receptor-like module | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
Calpain large subunit, middle domain (domain III) | 0 | Direct |
L27 domain | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
BRCT domain | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
Bet v1-like | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
PLP-dependent transferases | 0 | Direct |
PP2C-like | 0 | Direct |
GroES-like | 0 | Direct |
Acetyl-CoA synthetase-like | 0 | Direct |
NTF2-like | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
Translation proteins SH3-like domain | 0 | Direct |
RNA-binding domain, RBD | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
GST C-terminal domain-like | 0 | Direct |
Ricin B-like lectins | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
L domain-like | 0 | Direct |
TNF receptor-like | 0 | Direct |
Plakin repeat | 0 | Direct |
CoA-dependent acyltransferases | 0 | Direct |
SMAD/FHA domain | 0 | Direct |
Hedgehog/intein (Hint) domain | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
GFP-like | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
Translational machinery components | 0 | Direct |
Homeodomain-like | 0 | Direct |
UBA-like | 0 | Direct |
Voltage-gated potassium channels | 0 | Direct |
"Winged helix" DNA-binding domain | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
Galactose-binding domain-like | 0 | Direct |
FnI-like domain | 0 | Direct |
CCHHC domain | 0 | Direct |
Single hybrid motif | 0 | Direct |
TATA-box binding protein-like | 0 | Direct |
UBC-like | 0 | Direct |
DNA/RNA polymerases | 0 | Direct |
Nuclear receptor coactivator interlocking domain | 0 | Direct |
SRF-like | 0 | Direct |
LCCL domain | 0 | Direct |
Chaperone J-domain | 0 | Direct |
Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
HMG-box | 0 | Direct |
TPR-like | 0 | Direct |
Ribosomal protein S5 domain 2-like | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
CCCH zinc finger | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
CBS-domain pair | 0 | Direct |
Kringle-like | 0 | Direct |
BRK domain-like | 0 | Direct |
PH domain-like | 0 | Direct |
PDZ domain-like | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
HAD-like | 0 | Direct |
Hemopexin-like domain | 0 | Direct |
Myosin rod fragments | 0 | Direct |
PGBD-like | 0 | Direct |
WW domain | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
ENTH/VHS domain | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Periplasmic binding protein-like I | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
Carbonic anhydrase | 0 | Direct |
Cupredoxins | 0 | Direct |
Sec7 domain | 0 | Direct |
Nuclear receptor ligand-binding domain | 0 | Direct |
FAD-linked reductases, C-terminal domain | 0 | Direct |
Periplasmic binding protein-like II | 0 | Direct |
JAB1/MPN domain | 0 | Direct |
G protein-binding domain | 0 | Direct |
Orange domain-like | 0 | Direct |
Integrin alpha N-terminal domain | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
TSP-1 type 1 repeat | 0 | Direct |
NHL repeat | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
ACT-like | 0 | Direct |
TNF-like | 0 | Direct |
BPTI-like | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
GLA-domain | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
SH2 domain | 0 | Direct |
Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
Cytochrome P450 | 0 | Direct |
Kelch motif | 0 | Direct |
Nucleotidylyl transferase | 0 | Direct |
DPP6 N-terminal domain-like | 0 | Direct |
Cullin repeat-like | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
Actin-like ATPase domain | 0 | Direct |
Polo-box domain | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
Metallo-dependent hydrolases | 0 | Direct |
Metallo-dependent phosphatases | 0 | Direct |
Nicotinic receptor ligand binding domain-like | 0 | Direct |
Aldolase | 0 | Direct |
4-helical cytokines | 0 | Direct |
SNARE-like | 0 | Direct |
Spectrin repeat | 0 | Direct |
SH3-domain | 0 | Direct |
MFS general substrate transporter | 0 | Direct |
SET domain | 0 | Direct |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
Chromo domain-like | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
beta-beta-alpha zinc fingers | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
PAZ domain | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
CalX-like | 0 | Direct |
Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
Hedgehog/DD-peptidase | 0 | Direct |
Composite domain of metallo-dependent hydrolases | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
EGF/Laminin | 0 | Direct |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
Insulin-like | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
(Trans)glycosidases | 0 | Direct |
vWA-like | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
alpha/beta-Hydrolases | 0 | Direct |
Leucine zipper domain | 0 | Direct |
STAT | 0 | Direct |
Snake toxin-like | 0 | Direct |
dsRNA-binding domain-like | 0 | Direct |
RuvA domain 2-like | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
Family A G protein-coupled receptor-like | 0 | Direct |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
PX domain | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
GTPase activation domain, GAP | 0 | Direct |
Sema domain | 0 | Direct |
Hormone receptor domain | 0 | Direct |
Nucleotide cyclase | 0 | Direct |
Zn-dependent exopeptidases | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
POZ domain | 0 | Direct |
Ras GEF | 0 | Direct |
Notch domain | 0 | Direct |
SNARE fusion complex | 0 | Direct |
Thioredoxin-like | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
FAS1 domain | 0 | Direct |
Heme-dependent peroxidases | 0 | Direct |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
E set domains | 0 | Direct |
DHS-like NAD/FAD-binding domain | 0 | Direct |
Cystine-knot cytokines | 0 | Direct |
HCP-like | 0 | Direct |
DNase I-like | 0 | Direct |
Cyclin-like | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
(Phosphotyrosine protein) phosphatases II | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
MAPEG domain-like | 0 | Direct |
Cysteine proteinases | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
WD40 repeat-like | 0.8511 | Inherited |
Immunoglobulin | 0.8511 | Inherited |
Fibronectin type III | 0.8986 | Inherited |
Concanavalin A-like lectins/glucanases | 0.9103 | Inherited |
Ankyrin repeat | 0.9513 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this ZA term (Not in SDZA)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
SPRY domain | 0 | DIRECT |
Matrix metalloproteases, catalytic domain | 0 | DIRECT |
Netrin-like domain (NTR/C345C module) | 0 | DIRECT |
Fibroblast growth factors (FGF) | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
Transcription factor STAT-4 N-domain | 0 | DIRECT |
SRF-like | 0 | DIRECT |
EF-hand modules in multidomain proteins | 0 | DIRECT |
N-acetyl transferase, NAT | 0 | DIRECT |
p53 tetramerization domain | 0 | DIRECT |
GLA-domain | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Elongation factors | 0 | DIRECT |
UBA domain | 0 | DIRECT |
Intermediate filament protein, coiled coil region | 0 | DIRECT |
PWWP domain | 0 | DIRECT |
Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
Leucine zipper domain | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
Protein kinases, catalytic subunit | 0 | DIRECT |
FCH domain | 0 | DIRECT |
Arrestin/Vps26-like | 0 | DIRECT |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
FAD-linked reductases, N-terminal domain | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
SAM (sterile alpha motif) domain | 0 | DIRECT |
Platelet-derived growth factor-like | 0 | DIRECT |
DNA polymerase I | 0 | DIRECT |
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
Actin/HSP70 | 0 | DIRECT |
Mammalian PLC | 0 | DIRECT |
Hsp90 middle domain | 0 | DIRECT |
F-box domain | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
Carbonic anhydrase | 0 | DIRECT |
Extended AAA-ATPase domain | 0 | DIRECT |
Enabled/VASP homology 1 domain (EVH1 domain) | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
Fatty acid binding protein-like | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Hedgehog C-terminal (Hog) autoprocessing domain | 0 | DIRECT |
Ephrin receptor ligand binding domain | 0 | DIRECT |
G proteins | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
Motor proteins | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
L domain | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
Laminin G-like module | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
Nitrogenase iron protein-like | 0 | DIRECT |
Cadherin | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
Laminin-type module | 0 | DIRECT |
cAMP-binding domain | 0 | DIRECT |
Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
Classic zinc finger, C2H2 | 0 | DIRECT |
Biotinyl/lipoyl-carrier proteins and domains | 0 | DIRECT |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | DIRECT |
CalX-beta domain | 0 | DIRECT |
LDL receptor-like module | 0 | DIRECT |
ABC transporter transmembrane region | 0 | DIRECT |
MYND zinc finger | 0 | DIRECT |
BAR domain | 0 | DIRECT |
RhoGDI-like | 0 | DIRECT |
p120GAP domain-like | 0 | DIRECT |
Eukaryotic proteases | 0 | DIRECT |
L27 domain | 0 | DIRECT |
Homeodomain | 0 | DIRECT |
Histone lysine methyltransferases | 0 | DIRECT |
PX domain | 0 | DIRECT |
P4 origin-binding domain-like | 0 | DIRECT |
Ephrin ectodomain | 0 | DIRECT |
Cytoplasmic domain of inward rectifier potassium channel | 0 | DIRECT |
Anion transport protein, cytoplasmic domain | 0 | DIRECT |
V set domains (antibody variable domain-like) | 0 | DIRECT |
Sema domain | 0 | DIRECT |
DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
28-residue LRR | 0 | DIRECT |
Clathrin coat assembly domain | 0 | DIRECT |
Calmodulin-like | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
ABC transporter ATPase domain-like | 0 | DIRECT |
PHD domain | 0 | DIRECT |
Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
Adenylyl and guanylyl cyclase catalytic domain | 0 | DIRECT |
Dual specificity phosphatase-like | 0 | DIRECT |
Small Kunitz-type inhibitors & BPTI-like toxins | 0 | DIRECT |
Tudor domain | 0 | DIRECT |
PAZ domain | 0 | DIRECT |
Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
Transforming growth factor (TGF)-beta | 0 | DIRECT |
Paired domain | 0 | DIRECT |
Penta-EF-hand proteins | 0 | DIRECT |
Ras-binding domain, RBD | 0 | DIRECT |
Hedgehog (development protein), N-terminal signaling domain | 0 | DIRECT |
Plakophilin 1 helical region | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
POU-specific domain | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
TNF-like | 0 | DIRECT |
Caspase recruitment domain, CARD | 0 | DIRECT |
Rhodopsin-like | 0 | DIRECT |
C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Histone deacetylase, HDAC | 0 | DIRECT |
Myeloperoxidase-like | 0 | DIRECT |
Nucleoplasmin-like core domain | 0 | DIRECT |
Tubulin, GTPase domain | 0 | DIRECT |
PLC-like (P variant) | 0 | DIRECT |
Diap1 N-terninal region-like | 0 | DIRECT |
RUNT domain | 0 | DIRECT |
Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
Noncollagenous (NC1) domain of collagen IV | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
Integrin A (or I) domain | 0 | DIRECT |
Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
Pyridoxal-dependent decarboxylase | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
PDZ domain | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Ngr ectodomain-like | 0 | DIRECT |
Phenylalanine metabolism regulatory domain | 0 | DIRECT |
Insulin-like | 0 | DIRECT |
PAPS sulfotransferase | 0 | DIRECT |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
DEATH domain, DD | 0 | DIRECT |
Hairy Orange domain | 0 | DIRECT |
Tubulin, C-terminal domain | 0 | DIRECT |
Myb/SANT domain | 0 | DIRECT |
CCHHC domain | 0 | DIRECT |
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
STAT | 0 | DIRECT |
Link domain | 0 | DIRECT |
RecA protein-like (ATPase-domain) | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Fibronectin type II module | 0 | DIRECT |
LCCL domain | 0 | DIRECT |
Connexin43 | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
ets domain | 0 | DIRECT |
CUT domain | 0 | DIRECT |
Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
Regulator of chromosome condensation RCC1 | 0 | DIRECT |
Proprotein convertase P-domain | 0 | DIRECT |
Short-chain cytokines | 0 | DIRECT |
p53 DNA-binding domain-like | 0 | DIRECT |
T-box | 0 | DIRECT |
Reprolysin-like | 0 | DIRECT |
Nucleotide and nucleoside kinases | 0 | DIRECT |
Choline/Carnitine O-acyltransferase | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
Nicotinic receptor ligand binding domain-like | 0 | DIRECT |
Extracellular domain of cell surface receptors | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
Papain-like | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
Filamin repeat (rod domain) | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
Troponin T | 0 | DIRECT |
TNF receptor-like | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Nuclear receptor | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
SMAD domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
Tetratricopeptide repeat (TPR) | 0 | DIRECT |
Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
FAS1 domain | 0 | DIRECT |
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
Arginine methyltransferase | 0 | DIRECT |
Voltage-gated potassium channels | 0 | DIRECT |
Zf-UBP | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
Cyclin | 0 | DIRECT |
Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
Chromo domain | 0 | DIRECT |
LIM domain | 0 | DIRECT |
PB1 domain | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
Dachshund-homology domain | 0 | DIRECT |
SH2 domain | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
Synaptotagmin-like (S variant) | 0 | DIRECT |
Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
Moesin tail domain | 0 | DIRECT |
EGF-type module | 0 | DIRECT |
Subtilases | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
Cold shock DNA-binding domain-like | 0 | DIRECT |
Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
Erythroid transcription factor GATA-1 | 0 | DIRECT |
Third domain of FERM | 0 | DIRECT |
VWC domain | 0 | DIRECT |
TBP-associated factors, TAFs | 0 | DIRECT |
Forkhead DNA-binding domain | 0 | DIRECT |
Tetramerization domain of potassium channels | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
C-type lectin domain | 0 | DIRECT |
DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
MAPEG domain | 0 | DIRECT |
PKD domain | 0 | DIRECT |
Armadillo repeat | 0 | DIRECT |
Plakin repeat | 0 | DIRECT |
UBC-related | 0 | DIRECT |
Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
Long-chain cytokines | 0 | DIRECT |
Myotubularin-like phosphatases | 0 | DIRECT |
Flavin-binding PAS domain | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
L-arabinose binding protein-like | 0 | DIRECT |
Protein serine/threonine phosphatase | 0 | DIRECT |
Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
HMG-box | 0 | DIRECT |
Prohormone convertase 1 pro-domain | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
Caspase catalytic domain | 0 | DIRECT |
First domain of FERM | 0 | DIRECT |
WW domain | 0 | DIRECT |
BTB/POZ domain | 0 | DIRECT |
Domain G2 of nidogen-1 | 0 | DIRECT |
Interleukin 8-like chemokines | 0 | DIRECT |
Glutathione S-transferase (GST), C-terminal domain | 0 | DIRECT |
Ubiquitin-related | 0 | DIRECT |
Nuclear receptor ligand-binding domain | 0 | DIRECT |
STAT DNA-binding domain | 0 | DIRECT |
BCR-homology GTPase activation domain (BH-domain) | 0 | DIRECT |
Clathrin adaptor core protein | 0 | DIRECT |
Tyrosine-dependent oxidoreductases | 0 | DIRECT |
Cell cycle transcription factor e2f-dp | 0 | DIRECT |
Cytochrome P450 | 0 | DIRECT |
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
PP2C-like | 0 | DIRECT |
Notch domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
Ras GEF | 0 | DIRECT |
Pentraxin (pentaxin) | 0 | DIRECT |
Cdc48 N-terminal domain-like | 0 | DIRECT |
Tandem AAA-ATPase domain | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
FHA domain | 0 | DIRECT |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
GABA-aminotransferase-like | 0 | DIRECT |
MMP N-terminal domain | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
TSP-1 type 1 repeat | 0 | DIRECT |
Acetyl-CoA synthetase-like | 0 | DIRECT |
Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
Myosin rod fragments | 0 | DIRECT |
Ovomucoid domain III-like | 0 | DIRECT |
Single strand DNA-binding domain, SSB | 0 | DIRECT |
Hemopexin-like domain | 0 | DIRECT |
Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
BRK domain-like | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
Canonical RBD | 0 | DIRECT |
SWIRM domain | 0 | DIRECT |
Integrin alpha N-terminal domain | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
WD40-repeat | 0.9019 | INHERITED FROM: photoreceptor outer segment layer || retinal cone cell |
Fibronectin type III | 0.9019 | INHERITED FROM: white matter || synencephalon || medial longitudinal fasciculus || glomerular layer |
I set domains | 0.949 | INHERITED FROM: white matter || synencephalon || medial longitudinal fasciculus |
Ankyrin repeat | 0.954 | INHERITED FROM: radial glial cell |
SCOP term | FDR (all) | Annotation (direct or inherited) |
SPRY domain | 0 | Direct |
Matrix metalloproteases, catalytic domain | 0 | Direct |
Netrin-like domain (NTR/C345C module) | 0 | Direct |
Fibroblast growth factors (FGF) | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
Calpain large subunit, middle domain (domain III) | 0 | Direct |
Transcription factor STAT-4 N-domain | 0 | Direct |
SRF-like | 0 | Direct |
EF-hand modules in multidomain proteins | 0 | Direct |
N-acetyl transferase, NAT | 0 | Direct |
p53 tetramerization domain | 0 | Direct |
GLA-domain | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Elongation factors | 0 | Direct |
UBA domain | 0 | Direct |
Intermediate filament protein, coiled coil region | 0 | Direct |
PWWP domain | 0 | Direct |
Phosphotyrosine-binding domain (PTB) | 0 | Direct |
Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
Leucine zipper domain | 0 | Direct |
Bromodomain | 0 | Direct |
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
Protein kinases, catalytic subunit | 0 | Direct |
FCH domain | 0 | Direct |
Arrestin/Vps26-like | 0 | Direct |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
FAD-linked reductases, N-terminal domain | 0 | Direct |
NHL repeat | 0 | Direct |
SAM (sterile alpha motif) domain | 0 | Direct |
Platelet-derived growth factor-like | 0 | Direct |
DNA polymerase I | 0 | Direct |
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
Actin/HSP70 | 0 | Direct |
Mammalian PLC | 0 | Direct |
Hsp90 middle domain | 0 | Direct |
F-box domain | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
Carbonic anhydrase | 0 | Direct |
Extended AAA-ATPase domain | 0 | Direct |
Enabled/VASP homology 1 domain (EVH1 domain) | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
Fatty acid binding protein-like | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Hedgehog C-terminal (Hog) autoprocessing domain | 0 | Direct |
Ephrin receptor ligand binding domain | 0 | Direct |
G proteins | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
Hydantoinase (dihydropyrimidinase) | 0 | Direct |
Motor proteins | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Sec7 domain | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
SNARE fusion complex | 0 | Direct |
L domain | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
Laminin G-like module | 0 | Direct |
Aquaporin-like | 0 | Direct |
Nitrogenase iron protein-like | 0 | Direct |
Cadherin | 0 | Direct |
Tropomyosin | 0 | Direct |
Laminin-type module | 0 | Direct |
cAMP-binding domain | 0 | Direct |
Class I glutamine amidotransferases (GAT) | 0 | Direct |
Classic zinc finger, C2H2 | 0 | Direct |
Biotinyl/lipoyl-carrier proteins and domains | 0 | Direct |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | Direct |
CalX-beta domain | 0 | Direct |
LDL receptor-like module | 0 | Direct |
ABC transporter transmembrane region | 0 | Direct |
MYND zinc finger | 0 | Direct |
BAR domain | 0 | Direct |
RhoGDI-like | 0 | Direct |
p120GAP domain-like | 0 | Direct |
Eukaryotic proteases | 0 | Direct |
L27 domain | 0 | Direct |
Homeodomain | 0 | Direct |
Histone lysine methyltransferases | 0 | Direct |
PX domain | 0 | Direct |
P4 origin-binding domain-like | 0 | Direct |
Ephrin ectodomain | 0 | Direct |
Cytoplasmic domain of inward rectifier potassium channel | 0 | Direct |
Anion transport protein, cytoplasmic domain | 0 | Direct |
V set domains (antibody variable domain-like) | 0 | Direct |
Sema domain | 0 | Direct |
DnaQ-like 3'-5' exonuclease | 0 | Direct |
28-residue LRR | 0 | Direct |
Clathrin coat assembly domain | 0 | Direct |
Calmodulin-like | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
ABC transporter ATPase domain-like | 0 | Direct |
PHD domain | 0 | Direct |
Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
Adenylyl and guanylyl cyclase catalytic domain | 0 | Direct |
Dual specificity phosphatase-like | 0 | Direct |
Small Kunitz-type inhibitors & BPTI-like toxins | 0 | Direct |
Tudor domain | 0 | Direct |
PAZ domain | 0 | Direct |
Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | Direct |
Plexin repeat | 0 | Direct |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
Transforming growth factor (TGF)-beta | 0 | Direct |
Paired domain | 0 | Direct |
Penta-EF-hand proteins | 0 | Direct |
Ras-binding domain, RBD | 0 | Direct |
Hedgehog (development protein), N-terminal signaling domain | 0 | Direct |
Plakophilin 1 helical region | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
POU-specific domain | 0 | Direct |
Cap-Gly domain | 0 | Direct |
TNF-like | 0 | Direct |
Caspase recruitment domain, CARD | 0 | Direct |
Rhodopsin-like | 0 | Direct |
C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
Cell cycle control phosphatase, catalytic domain | 0 | Direct |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
CBS-domain pair | 0 | Direct |
Histone deacetylase, HDAC | 0 | Direct |
Myeloperoxidase-like | 0 | Direct |
Nucleoplasmin-like core domain | 0 | Direct |
Tubulin, GTPase domain | 0 | Direct |
PLC-like (P variant) | 0 | Direct |
Diap1 N-terninal region-like | 0 | Direct |
RUNT domain | 0 | Direct |
Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
Noncollagenous (NC1) domain of collagen IV | 0 | Direct |
Second domain of FERM | 0 | Direct |
Integrin A (or I) domain | 0 | Direct |
Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
Pyridoxal-dependent decarboxylase | 0 | Direct |
CCCH zinc finger | 0 | Direct |
PDZ domain | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Ngr ectodomain-like | 0 | Direct |
Phenylalanine metabolism regulatory domain | 0 | Direct |
Insulin-like | 0 | Direct |
PAPS sulfotransferase | 0 | Direct |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
DEATH domain, DD | 0 | Direct |
Hairy Orange domain | 0 | Direct |
Tubulin, C-terminal domain | 0 | Direct |
Myb/SANT domain | 0 | Direct |
CCHHC domain | 0 | Direct |
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | Direct |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
STAT | 0 | Direct |
Link domain | 0 | Direct |
RecA protein-like (ATPase-domain) | 0 | Direct |
MIR domain | 0 | Direct |
Fibronectin type II module | 0 | Direct |
LCCL domain | 0 | Direct |
Connexin43 | 0 | Direct |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
ets domain | 0 | Direct |
CUT domain | 0 | Direct |
Anticodon-binding domain of Class II aaRS | 0 | Direct |
Regulator of chromosome condensation RCC1 | 0 | Direct |
Proprotein convertase P-domain | 0 | Direct |
Short-chain cytokines | 0 | Direct |
p53 DNA-binding domain-like | 0 | Direct |
T-box | 0 | Direct |
Reprolysin-like | 0 | Direct |
Nucleotide and nucleoside kinases | 0 | Direct |
Choline/Carnitine O-acyltransferase | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
Nicotinic receptor ligand binding domain-like | 0 | Direct |
Extracellular domain of cell surface receptors | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
Papain-like | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
Filamin repeat (rod domain) | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
Troponin T | 0 | Direct |
TNF receptor-like | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Nuclear receptor | 0 | Direct |
SH3-domain | 0 | Direct |
Hormone receptor domain | 0 | Direct |
SMAD domain | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
Tetratricopeptide repeat (TPR) | 0 | Direct |
Nuclear receptor coactivator interlocking domain | 0 | Direct |
FAS1 domain | 0 | Direct |
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
Arginine methyltransferase | 0 | Direct |
Voltage-gated potassium channels | 0 | Direct |
Zf-UBP | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
Cyclin | 0 | Direct |
Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
Chromo domain | 0 | Direct |
LIM domain | 0 | Direct |
PB1 domain | 0 | Direct |
Smc hinge domain | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
Dachshund-homology domain | 0 | Direct |
SH2 domain | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
Synaptotagmin-like (S variant) | 0 | Direct |
Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
Moesin tail domain | 0 | Direct |
EGF-type module | 0 | Direct |
Subtilases | 0 | Direct |
Chaperone J-domain | 0 | Direct |
Cold shock DNA-binding domain-like | 0 | Direct |
Pleckstrin-homology domain (PH domain) | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
Erythroid transcription factor GATA-1 | 0 | Direct |
Third domain of FERM | 0 | Direct |
VWC domain | 0 | Direct |
TBP-associated factors, TAFs | 0 | Direct |
Forkhead DNA-binding domain | 0 | Direct |
Tetramerization domain of potassium channels | 0 | Direct |
YWTD domain | 0 | Direct |
C-type lectin domain | 0 | Direct |
DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
MAPEG domain | 0 | Direct |
PKD domain | 0 | Direct |
Armadillo repeat | 0 | Direct |
Plakin repeat | 0 | Direct |
UBC-related | 0 | Direct |
Meta-cation ATPase, catalytic domain P | 0 | Direct |
Long-chain cytokines | 0 | Direct |
Myotubularin-like phosphatases | 0 | Direct |
Flavin-binding PAS domain | 0 | Direct |
Spectrin repeat | 0 | Direct |
L-arabinose binding protein-like | 0 | Direct |
Protein serine/threonine phosphatase | 0 | Direct |
Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
HMG-box | 0 | Direct |
Prohormone convertase 1 pro-domain | 0 | Direct |
Integrin domains | 0 | Direct |
Caspase catalytic domain | 0 | Direct |
First domain of FERM | 0 | Direct |
WW domain | 0 | Direct |
BTB/POZ domain | 0 | Direct |
Domain G2 of nidogen-1 | 0 | Direct |
Interleukin 8-like chemokines | 0 | Direct |
Glutathione S-transferase (GST), C-terminal domain | 0 | Direct |
Ubiquitin-related | 0 | Direct |
Nuclear receptor ligand-binding domain | 0 | Direct |
STAT DNA-binding domain | 0 | Direct |
BCR-homology GTPase activation domain (BH-domain) | 0 | Direct |
Clathrin adaptor core protein | 0 | Direct |
Tyrosine-dependent oxidoreductases | 0 | Direct |
Cell cycle transcription factor e2f-dp | 0 | Direct |
Cytochrome P450 | 0 | Direct |
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 0 | Direct |
ALDH-like | 0 | Direct |
Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
PP2C-like | 0 | Direct |
Notch domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Kelch motif | 0 | Direct |
Ras GEF | 0 | Direct |
Pentraxin (pentaxin) | 0 | Direct |
Cdc48 N-terminal domain-like | 0 | Direct |
Tandem AAA-ATPase domain | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
FHA domain | 0 | Direct |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
GABA-aminotransferase-like | 0 | Direct |
MMP N-terminal domain | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
TSP-1 type 1 repeat | 0 | Direct |
Acetyl-CoA synthetase-like | 0 | Direct |
Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
Myosin rod fragments | 0 | Direct |
Ovomucoid domain III-like | 0 | Direct |
Single strand DNA-binding domain, SSB | 0 | Direct |
Hemopexin-like domain | 0 | Direct |
Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
BRK domain-like | 0 | Direct |
Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
Canonical RBD | 0 | Direct |
SWIRM domain | 0 | Direct |
Integrin alpha N-terminal domain | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
WD40-repeat | 0.9019 | Inherited |
Fibronectin type III | 0.9019 | Inherited |
I set domains | 0.949 | Inherited |
Ankyrin repeat | 0.954 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this ZA term (Not in SPZA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
MAPEG domain-like | 0 | DIRECT |
GFP-like | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Hedgehog/DD-peptidase | 0 | DIRECT |
HSP20-like chaperones | 0 | DIRECT |
LDL receptor-like module | 0 | DIRECT |
NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
E set domains | 0 | DIRECT |
BRK domain-like | 0 | DIRECT |
Nucleotidylyl transferase | 0 | DIRECT |
Protein kinase-like (PK-like) | 0 | DIRECT |
C-type lectin-like | 0 | DIRECT |
Hemopexin-like domain | 0 | DIRECT |
L domain-like | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
CoA-dependent acyltransferases | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
UBA-like | 0 | DIRECT |
Doublecortin (DC) | 0 | DIRECT |
Nicotinic receptor ligand binding domain-like | 0 | DIRECT |
4-helical cytokines | 0 | DIRECT |
G protein-binding domain | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
TNF receptor-like | 0 | DIRECT |
Cytokine | 0 | DIRECT |
"Winged helix" DNA-binding domain | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
SMAD/FHA domain | 0 | DIRECT |
TIMP-like | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
PLP-dependent transferases | 0 | DIRECT |
Moesin tail domain | 0 | DIRECT |
Translational machinery components | 0 | DIRECT |
Thioredoxin-like | 0 | DIRECT |
Protease propeptides/inhibitors | 0 | DIRECT |
Serine protease inhibitors | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
ENTH/VHS domain | 0 | DIRECT |
Actin-like ATPase domain | 0 | DIRECT |
UBC-like | 0 | DIRECT |
MFS general substrate transporter | 0 | DIRECT |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
FAS1 domain | 0 | DIRECT |
Kazal-type serine protease inhibitors | 0 | DIRECT |
HIT-like | 0 | DIRECT |
Acetyl-CoA synthetase-like | 0 | DIRECT |
Zinc beta-ribbon | 0 | DIRECT |
Caspase-like | 0 | DIRECT |
PKD domain | 0 | DIRECT |
Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
Periplasmic binding protein-like I | 0 | DIRECT |
Intermediate filament protein, coiled coil region | 0 | DIRECT |
BPTI-like | 0 | DIRECT |
Carbonic anhydrase | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
Cysteine proteinases | 0 | DIRECT |
Nucleoplasmin-like core domain | 0 | DIRECT |
Family A G protein-coupled receptor-like | 0 | DIRECT |
Kringle-like | 0 | DIRECT |
Soluble quinoprotein glucose dehydrogenase | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
HAD-like | 0 | DIRECT |
Aquaporin-like | 0 | DIRECT |
RuvA domain 2-like | 0 | DIRECT |
SAM/Pointed domain | 0 | DIRECT |
Nuclear receptor ligand-binding domain | 0 | DIRECT |
SET domain | 0 | DIRECT |
Subtilisin-like | 0 | DIRECT |
Heme-dependent peroxidases | 0 | DIRECT |
Periplasmic binding protein-like II | 0 | DIRECT |
Lipocalins | 0 | DIRECT |
PLC-like phosphodiesterases | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
CalX-like | 0 | DIRECT |
Translation proteins SH3-like domain | 0 | DIRECT |
CCHHC domain | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
HCP-like | 0 | DIRECT |
DUSP-like | 0 | DIRECT |
Single hybrid motif | 0 | DIRECT |
MIR domain | 0 | DIRECT |
GST C-terminal domain-like | 0 | DIRECT |
PH domain-like | 0 | DIRECT |
Zn-dependent exopeptidases | 0 | DIRECT |
Leucine zipper domain | 0 | DIRECT |
TATA-box binding protein-like | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
PP2C-like | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
SNARE-like | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
Cyclin-like | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
EF-hand | 0 | DIRECT |
Orange domain-like | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
Homeodomain-like | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
PDZ domain-like | 0 | DIRECT |
ADC-like | 0 | DIRECT |
L27 domain | 0 | DIRECT |
Sema domain | 0 | DIRECT |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
Ras GEF | 0 | DIRECT |
Histone-fold | 0 | DIRECT |
CCCH zinc finger | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
Ribonuclease H-like | 0 | DIRECT |
DNA/RNA polymerases | 0 | DIRECT |
Cystine-knot cytokines | 0 | DIRECT |
FAD-linked reductases, C-terminal domain | 0 | DIRECT |
ACT-like | 0 | DIRECT |
Nucleotide cyclase | 0 | DIRECT |
PAZ domain | 0 | DIRECT |
TPR-like | 0 | DIRECT |
F-box domain | 0 | DIRECT |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
Bet v1-like | 0 | DIRECT |
(Trans)glycosidases | 0 | DIRECT |
Tricorn protease domain 2 | 0 | DIRECT |
Transcription factor STAT-4 N-domain | 0 | DIRECT |
SH3-domain | 0 | DIRECT |
Ricin B-like lectins | 0 | DIRECT |
SWIB/MDM2 domain | 0 | DIRECT |
Ribosomal protein S5 domain 2-like | 0 | DIRECT |
vWA-like | 0 | DIRECT |
Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
BRCT domain | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
p53 tetramerization domain | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
Hormone receptor domain | 0 | DIRECT |
beta-beta-alpha zinc fingers | 0 | DIRECT |
Class II aaRS ABD-related | 0 | DIRECT |
p53-like transcription factors | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
GLA-domain | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
PGBD-like | 0 | DIRECT |
Thyroglobulin type-1 domain | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
Ubiquitin-like | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
DPP6 N-terminal domain-like | 0 | DIRECT |
PX domain | 0 | DIRECT |
DHS-like NAD/FAD-binding domain | 0 | DIRECT |
HD-domain/PDEase-like | 0 | DIRECT |
Translation proteins | 0 | DIRECT |
Notch domain | 0 | DIRECT |
Polo-box domain | 0 | DIRECT |
Cytochrome P450 | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Calponin-homology domain, CH-domain | 0 | DIRECT |
WW domain | 0 | DIRECT |
POZ domain | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
alpha/beta-Hydrolases | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
HSP90 C-terminal domain | 0 | DIRECT |
Chaperone J-domain | 0 | DIRECT |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
ALDH-like | 0 | DIRECT |
Spectrin repeat | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
SH2 domain | 0 | DIRECT |
Hedgehog/intein (Hint) domain | 0 | DIRECT |
GTPase activation domain, GAP | 0 | DIRECT |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
Insulin-like | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
RNA-binding domain, RBD | 0 | DIRECT |
Terpenoid cyclases/Protein prenyltransferases | 0 | DIRECT |
Class II aaRS and biotin synthetases | 0 | DIRECT |
Myosin rod fragments | 0 | DIRECT |
Galactose-binding domain-like | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
ADP-ribosylation | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
Snake toxin-like | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
Plakin repeat | 0 | DIRECT |
SRF-like | 0 | DIRECT |
Aldolase | 0 | DIRECT |
HMG-box | 0 | DIRECT |
Tubulin nucleotide-binding domain-like | 0 | DIRECT |
EGF/Laminin | 0 | DIRECT |
ABC transporter transmembrane region | 0 | DIRECT |
Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
Cysteine-rich domain | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
TSP-1 type 1 repeat | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Metallo-dependent hydrolases | 0 | DIRECT |
Voltage-gated potassium channels | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
Nucleic acid-binding proteins | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
dsRNA-binding domain-like | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
Trypsin-like serine proteases | 0 | DIRECT |
TNF-like | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
CRAL/TRIO N-terminal domain | 0 | DIRECT |
STAT | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
Interleukin 8-like chemokines | 0 | DIRECT |
Phoshotransferase/anion transport protein | 0 | DIRECT |
Tudor/PWWP/MBT | 0 | DIRECT |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
(Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
Sec7 domain | 0 | DIRECT |
Cupredoxins | 0 | DIRECT |
Troponin coil-coiled subunits | 0 | DIRECT |
Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
FnI-like domain | 0 | DIRECT |
Tetraspanin | 0 | DIRECT |
ARM repeat | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
LCCL domain | 0 | DIRECT |
P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
Connexin43 | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
Integrin alpha N-terminal domain | 0 | DIRECT |
GroES-like | 0 | DIRECT |
JAB1/MPN domain | 0 | DIRECT |
Immunoglobulin | 0.8383 | INHERITED FROM: synencephalon || olfactory bulb glomerulus || medial longitudinal fasciculus || scale || white matter || glomerular layer |
WD40 repeat-like | 0.8383 | INHERITED FROM: sensory system || eye || retinal photoreceptor layer || photoreceptor outer segment layer || retinal outer nuclear layer |
Fibronectin type III | 0.8888 | INHERITED FROM: synencephalon || medial longitudinal fasciculus || white matter || glomerular layer |
Concanavalin A-like lectins/glucanases | 0.9024 | INHERITED FROM: epidermis |
Ankyrin repeat | 0.9479 | INHERITED FROM: radial glial cell || ventricular zone || neuroblast (sensu Vertebrata) |
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
MAPEG domain-like | 0 | Direct |
GFP-like | 0 | Direct |
YWTD domain | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Hedgehog/DD-peptidase | 0 | Direct |
HSP20-like chaperones | 0 | Direct |
LDL receptor-like module | 0 | Direct |
NAD(P)-binding Rossmann-fold domains | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
E set domains | 0 | Direct |
BRK domain-like | 0 | Direct |
Nucleotidylyl transferase | 0 | Direct |
Protein kinase-like (PK-like) | 0 | Direct |
C-type lectin-like | 0 | Direct |
Hemopexin-like domain | 0 | Direct |
L domain-like | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
CoA-dependent acyltransferases | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
UBA-like | 0 | Direct |
Doublecortin (DC) | 0 | Direct |
Nicotinic receptor ligand binding domain-like | 0 | Direct |
4-helical cytokines | 0 | Direct |
G protein-binding domain | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
TNF receptor-like | 0 | Direct |
Cytokine | 0 | Direct |
"Winged helix" DNA-binding domain | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
SMAD/FHA domain | 0 | Direct |
TIMP-like | 0 | Direct |
Smc hinge domain | 0 | Direct |
Second domain of FERM | 0 | Direct |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
PLP-dependent transferases | 0 | Direct |
Moesin tail domain | 0 | Direct |
Translational machinery components | 0 | Direct |
Thioredoxin-like | 0 | Direct |
Protease propeptides/inhibitors | 0 | Direct |
Serine protease inhibitors | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
ENTH/VHS domain | 0 | Direct |
Actin-like ATPase domain | 0 | Direct |
UBC-like | 0 | Direct |
MFS general substrate transporter | 0 | Direct |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
FAS1 domain | 0 | Direct |
Kazal-type serine protease inhibitors | 0 | Direct |
HIT-like | 0 | Direct |
Acetyl-CoA synthetase-like | 0 | Direct |
Zinc beta-ribbon | 0 | Direct |
Caspase-like | 0 | Direct |
PKD domain | 0 | Direct |
Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
Periplasmic binding protein-like I | 0 | Direct |
Intermediate filament protein, coiled coil region | 0 | Direct |
BPTI-like | 0 | Direct |
Carbonic anhydrase | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
DNase I-like | 0 | Direct |
Cysteine proteinases | 0 | Direct |
Nucleoplasmin-like core domain | 0 | Direct |
Family A G protein-coupled receptor-like | 0 | Direct |
Kringle-like | 0 | Direct |
Soluble quinoprotein glucose dehydrogenase | 0 | Direct |
Plexin repeat | 0 | Direct |
HAD-like | 0 | Direct |
Aquaporin-like | 0 | Direct |
RuvA domain 2-like | 0 | Direct |
SAM/Pointed domain | 0 | Direct |
Nuclear receptor ligand-binding domain | 0 | Direct |
SET domain | 0 | Direct |
Subtilisin-like | 0 | Direct |
Heme-dependent peroxidases | 0 | Direct |
Periplasmic binding protein-like II | 0 | Direct |
Lipocalins | 0 | Direct |
PLC-like phosphodiesterases | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
CalX-like | 0 | Direct |
Translation proteins SH3-like domain | 0 | Direct |
CCHHC domain | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
HCP-like | 0 | Direct |
DUSP-like | 0 | Direct |
Single hybrid motif | 0 | Direct |
MIR domain | 0 | Direct |
GST C-terminal domain-like | 0 | Direct |
PH domain-like | 0 | Direct |
Zn-dependent exopeptidases | 0 | Direct |
Leucine zipper domain | 0 | Direct |
TATA-box binding protein-like | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
PP2C-like | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
DEATH domain | 0 | Direct |
SNARE-like | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
Tropomyosin | 0 | Direct |
Cyclin-like | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
EF-hand | 0 | Direct |
Orange domain-like | 0 | Direct |
Metallo-dependent phosphatases | 0 | Direct |
Homeodomain-like | 0 | Direct |
Integrin domains | 0 | Direct |
PDZ domain-like | 0 | Direct |
ADC-like | 0 | Direct |
L27 domain | 0 | Direct |
Sema domain | 0 | Direct |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
Ras GEF | 0 | Direct |
Histone-fold | 0 | Direct |
CCCH zinc finger | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
Ribonuclease H-like | 0 | Direct |
DNA/RNA polymerases | 0 | Direct |
Cystine-knot cytokines | 0 | Direct |
FAD-linked reductases, C-terminal domain | 0 | Direct |
ACT-like | 0 | Direct |
Nucleotide cyclase | 0 | Direct |
PAZ domain | 0 | Direct |
TPR-like | 0 | Direct |
F-box domain | 0 | Direct |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
Bet v1-like | 0 | Direct |
(Trans)glycosidases | 0 | Direct |
Tricorn protease domain 2 | 0 | Direct |
Transcription factor STAT-4 N-domain | 0 | Direct |
SH3-domain | 0 | Direct |
Ricin B-like lectins | 0 | Direct |
SWIB/MDM2 domain | 0 | Direct |
Ribosomal protein S5 domain 2-like | 0 | Direct |
vWA-like | 0 | Direct |
Composite domain of metallo-dependent hydrolases | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
BRCT domain | 0 | Direct |
Cullin repeat-like | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Kelch motif | 0 | Direct |
p53 tetramerization domain | 0 | Direct |
NHL repeat | 0 | Direct |
Cadherin-like | 0 | Direct |
Hormone receptor domain | 0 | Direct |
beta-beta-alpha zinc fingers | 0 | Direct |
Class II aaRS ABD-related | 0 | Direct |
p53-like transcription factors | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
Lipovitellin-phosvitin complex; beta-sheet shell regions | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
GLA-domain | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
PGBD-like | 0 | Direct |
Thyroglobulin type-1 domain | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
Ubiquitin-like | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
DPP6 N-terminal domain-like | 0 | Direct |
PX domain | 0 | Direct |
DHS-like NAD/FAD-binding domain | 0 | Direct |
HD-domain/PDEase-like | 0 | Direct |
Translation proteins | 0 | Direct |
Notch domain | 0 | Direct |
Polo-box domain | 0 | Direct |
Cytochrome P450 | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Calponin-homology domain, CH-domain | 0 | Direct |
WW domain | 0 | Direct |
POZ domain | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
alpha/beta-Hydrolases | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
HSP90 C-terminal domain | 0 | Direct |
Chaperone J-domain | 0 | Direct |
C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
ALDH-like | 0 | Direct |
Spectrin repeat | 0 | Direct |
NTF2-like | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
SH2 domain | 0 | Direct |
Hedgehog/intein (Hint) domain | 0 | Direct |
GTPase activation domain, GAP | 0 | Direct |
Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
Insulin-like | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
RNA-binding domain, RBD | 0 | Direct |
Terpenoid cyclases/Protein prenyltransferases | 0 | Direct |
Class II aaRS and biotin synthetases | 0 | Direct |
Myosin rod fragments | 0 | Direct |
Galactose-binding domain-like | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
ADP-ribosylation | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
Snake toxin-like | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
Plakin repeat | 0 | Direct |
SRF-like | 0 | Direct |
Aldolase | 0 | Direct |
HMG-box | 0 | Direct |
Tubulin nucleotide-binding domain-like | 0 | Direct |
EGF/Laminin | 0 | Direct |
ABC transporter transmembrane region | 0 | Direct |
Calpain large subunit, middle domain (domain III) | 0 | Direct |
Cysteine-rich domain | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
TSP-1 type 1 repeat | 0 | Direct |
CBS-domain pair | 0 | Direct |
Metallo-dependent hydrolases | 0 | Direct |
Voltage-gated potassium channels | 0 | Direct |
SNARE fusion complex | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
Nucleic acid-binding proteins | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
dsRNA-binding domain-like | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
Bromodomain | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
Trypsin-like serine proteases | 0 | Direct |
TNF-like | 0 | Direct |
Chromo domain-like | 0 | Direct |
CRAL/TRIO N-terminal domain | 0 | Direct |
STAT | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
Interleukin 8-like chemokines | 0 | Direct |
Phoshotransferase/anion transport protein | 0 | Direct |
Tudor/PWWP/MBT | 0 | Direct |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
(Phosphotyrosine protein) phosphatases II | 0 | Direct |
Sec7 domain | 0 | Direct |
Cupredoxins | 0 | Direct |
Troponin coil-coiled subunits | 0 | Direct |
Nuclear receptor coactivator interlocking domain | 0 | Direct |
FnI-like domain | 0 | Direct |
Tetraspanin | 0 | Direct |
ARM repeat | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
LCCL domain | 0 | Direct |
P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
Connexin43 | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
Integrin alpha N-terminal domain | 0 | Direct |
GroES-like | 0 | Direct |
JAB1/MPN domain | 0 | Direct |
Immunoglobulin | 0.8383 | Inherited |
WD40 repeat-like | 0.8383 | Inherited |
Fibronectin type III | 0.8888 | Inherited |
Concanavalin A-like lectins/glucanases | 0.9024 | Inherited |
Ankyrin repeat | 0.9479 | Inherited |
(show details)
Supra-domains annotated to this ZA term (Not in SPZA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,50729 50729 - PH domain-like 50729 - PH domain-like | 0 | DIRECT |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | DIRECT |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | DIRECT |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | DIRECT |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | DIRECT |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
55550,55550 55550 - SH2 domain 55550 - SH2 domain | 0 | DIRECT |
57440,57440 57440 - Kringle-like 57440 - Kringle-like | 0 | DIRECT |
69179,69179 69179 - Integrin domains 69179 - Integrin domains | 0 | DIRECT |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | DIRECT |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | DIRECT |
52058,57184 52058 - L domain-like 57184 - Growth factor receptor domain | 0 | DIRECT |
49417,55550 49417 - p53-like transcription factors 55550 - SH2 domain | 0 | DIRECT |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | DIRECT |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | DIRECT |
101288,50156 101288 - L27 domain 50156 - PDZ domain-like | 0 | DIRECT |
52058,49265 52058 - L domain-like 49265 - Fibronectin type III | 0 | DIRECT |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | DIRECT |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | DIRECT |
89837,89837 89837 - Doublecortin (DC) 89837 - Doublecortin (DC) | 0 | DIRECT |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
81324,81324 81324 - Voltage-gated potassium channels 81324 - Voltage-gated potassium channels | 0 | DIRECT |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
82109,100909 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
63501,50242 63501 - Frizzled cysteine-rich domain 50242 - TIMP-like | 0 | DIRECT |
69318,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains | 0 | DIRECT |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | DIRECT |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49785,57184 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain | 0 | DIRECT |
57586,57586 57586 - TNF receptor-like 57586 - TNF receptor-like | 0 | DIRECT |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | DIRECT |
46966,47473 46966 - Spectrin repeat 47473 - EF-hand | 0 | DIRECT |
56112,56112 56112 - Protein kinase-like (PK-like) 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like | 0 | DIRECT |
103575,81296 103575 - Plexin repeat 81296 - E set domains | 0 | DIRECT |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | DIRECT |
47986,52129 47986 - DEATH domain 52129 - Caspase-like | 0 | DIRECT |
63380,52343 63380 - Riboflavin synthase domain-like 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
49562,48350 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48350 - GTPase activation domain, GAP | 0 | DIRECT |
48092,47655 48092 - Transcription factor STAT-4 N-domain 47655 - STAT | 0 | DIRECT |
55166,51294 55166 - Hedgehog/DD-peptidase 51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
111418,81321 111418 - Hormone receptor domain 81321 - Family A G protein-coupled receptor-like | 0 | DIRECT |
57184,52058 57184 - Growth factor receptor domain 52058 - L domain-like | 0 | DIRECT |
49854,49785 49854 - Spermadhesin, CUB domain 49785 - Galactose-binding domain-like | 0 | DIRECT |
82199,57667 82199 - SET domain 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | DIRECT |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
90193,90193 90193 - Notch domain 90193 - Notch domain | 0 | DIRECT |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
57196,49854 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | DIRECT |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | DIRECT |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
47454,57959 47454 - A DNA-binding domain in eukaryotic transcription factors 57959 - Leucine zipper domain | 0 | DIRECT |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | DIRECT |
141072,141072 141072 - CalX-like 141072 - CalX-like | 0 | DIRECT |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | DIRECT |
51412,51412 51412 - Inosine monophosphate dehydrogenase (IMPDH) 51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | DIRECT |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53300,53300 53300 - vWA-like 53300 - vWA-like | 0 | DIRECT |
49785,49899 49785 - Galactose-binding domain-like 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | DIRECT |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | DIRECT |
55021,56534 55021 - ACT-like 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0 | DIRECT |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | DIRECT |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | DIRECT |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
56436,56436 56436 - C-type lectin-like 56436 - C-type lectin-like | 0 | DIRECT |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | DIRECT |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | DIRECT |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
57184,57603 57184 - Growth factor receptor domain 57603 - FnI-like domain | 0 | DIRECT |
46689,46689 46689 - Homeodomain-like 46689 - Homeodomain-like | 0 | DIRECT |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | DIRECT |
54001,143791 54001 - Cysteine proteinases 143791 - DUSP-like | 0 | DIRECT |
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | DIRECT |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50729,50044 50729 - PH domain-like 50044 - SH3-domain | 0 | DIRECT |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | DIRECT |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | DIRECT |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
49265,49899 49265 - Fibronectin type III 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
100909,49899 100909 - IP3 receptor type 1 binding core, domain 2 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
75399,75399 75399 - Plakin repeat 75399 - Plakin repeat | 0 | DIRECT |
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | DIRECT |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | DIRECT |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57603,57603 57603 - FnI-like domain 57603 - FnI-like domain | 0 | DIRECT |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | DIRECT |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0 | DIRECT |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | DIRECT |
90257,57997 90257 - Myosin rod fragments 57997 - Tropomyosin | 0 | DIRECT |
63825,57196 63825 - YWTD domain 57196 - EGF/Laminin | 0 | DIRECT |
52799,49562 52799 - (Phosphotyrosine protein) phosphatases II 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
48097,56112 48097 - Regulator of G-protein signaling, RGS 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0 | DIRECT |
57196,90193 57196 - EGF/Laminin 90193 - Notch domain | 0 | DIRECT |
82109,82109 82109 - MIR domain 82109 - MIR domain | 0 | DIRECT |
49854,57196 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin | 0 | DIRECT |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | DIRECT |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0 | DIRECT |
49417,47719 49417 - p53-like transcription factors 47719 - p53 tetramerization domain | 0 | DIRECT |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0 | DIRECT |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
82153,82153 82153 - FAS1 domain 82153 - FAS1 domain | 0 | DIRECT |
57850,57850 57850 - RING/U-box 57850 - RING/U-box | 0 | DIRECT |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | DIRECT |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0 | DIRECT |
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49758,47473 49758 - Calpain large subunit, middle domain (domain III) 47473 - EF-hand | 0 | DIRECT |
56112,47769 56112 - Protein kinase-like (PK-like) 47769 - SAM/Pointed domain | 0 | DIRECT |
48452,81901 48452 - TPR-like 81901 - HCP-like | 0 | DIRECT |
47655,49417 47655 - STAT 49417 - p53-like transcription factors | 0 | DIRECT |
49785,49785 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
48371,48371 48371 - ARM repeat 48371 - ARM repeat | 0 | DIRECT |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
103575,48726 103575 - Plexin repeat 48726 - Immunoglobulin | 0 | DIRECT |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9024 | INHERITED FROM: synencephalon || medial longitudinal fasciculus || white matter |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9855 | INHERITED FROM: synencephalon || brain nucleus || brainstem || medial longitudinal fasciculus || white matter |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50729,50729 50729 - PH domain-like 50729 - PH domain-like | 0 | Direct |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | Direct |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | Direct |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | Direct |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | Direct |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
55550,55550 55550 - SH2 domain 55550 - SH2 domain | 0 | Direct |
57440,57440 57440 - Kringle-like 57440 - Kringle-like | 0 | Direct |
69179,69179 69179 - Integrin domains 69179 - Integrin domains | 0 | Direct |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | Direct |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | Direct |
52058,57184 52058 - L domain-like 57184 - Growth factor receptor domain | 0 | Direct |
49417,55550 49417 - p53-like transcription factors 55550 - SH2 domain | 0 | Direct |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | Direct |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | Direct |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | Direct |
101288,50156 101288 - L27 domain 50156 - PDZ domain-like | 0 | Direct |
52058,49265 52058 - L domain-like 49265 - Fibronectin type III | 0 | Direct |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | Direct |
52283,51735 52283 - Formate/glycerate dehydrogenase catalytic domain-like 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
54001,49758 54001 - Cysteine proteinases 49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
56968,48431 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions 48431 - Lipovitellin-phosvitin complex, superhelical domain | 0 | Direct |
89837,89837 89837 - Doublecortin (DC) 89837 - Doublecortin (DC) | 0 | Direct |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
81324,81324 81324 - Voltage-gated potassium channels 81324 - Voltage-gated potassium channels | 0 | Direct |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
82109,100909 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
63501,50242 63501 - Frizzled cysteine-rich domain 50242 - TIMP-like | 0 | Direct |
69318,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains | 0 | Direct |
90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | Direct |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49785,57184 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain | 0 | Direct |
57586,57586 57586 - TNF receptor-like 57586 - TNF receptor-like | 0 | Direct |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | Direct |
46966,47473 46966 - Spectrin repeat 47473 - EF-hand | 0 | Direct |
56112,56112 56112 - Protein kinase-like (PK-like) 56112 - Protein kinase-like (PK-like) | 0 | Direct |
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like | 0 | Direct |
103575,81296 103575 - Plexin repeat 81296 - E set domains | 0 | Direct |
50729,47473 50729 - PH domain-like 47473 - EF-hand | 0 | Direct |
47986,52129 47986 - DEATH domain 52129 - Caspase-like | 0 | Direct |
63380,52343 63380 - Riboflavin synthase domain-like 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
49562,48350 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48350 - GTPase activation domain, GAP | 0 | Direct |
48092,47655 48092 - Transcription factor STAT-4 N-domain 47655 - STAT | 0 | Direct |
55166,51294 55166 - Hedgehog/DD-peptidase 51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
111418,81321 111418 - Hormone receptor domain 81321 - Family A G protein-coupled receptor-like | 0 | Direct |
57184,52058 57184 - Growth factor receptor domain 52058 - L domain-like | 0 | Direct |
49854,49785 49854 - Spermadhesin, CUB domain 49785 - Galactose-binding domain-like | 0 | Direct |
82199,57667 82199 - SET domain 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | Direct |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
90193,90193 90193 - Notch domain 90193 - Notch domain | 0 | Direct |
47473,51695 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
57196,49854 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | Direct |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | Direct |
57362,57362 57362 - BPTI-like 57362 - BPTI-like | 0 | Direct |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
47454,57959 47454 - A DNA-binding domain in eukaryotic transcription factors 57959 - Leucine zipper domain | 0 | Direct |
57196,63825 57196 - EGF/Laminin 63825 - YWTD domain | 0 | Direct |
141072,141072 141072 - CalX-like 141072 - CalX-like | 0 | Direct |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | Direct |
51412,51412 51412 - Inosine monophosphate dehydrogenase (IMPDH) 51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | Direct |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | Direct |
53300,53300 53300 - vWA-like 53300 - vWA-like | 0 | Direct |
49785,49899 49785 - Galactose-binding domain-like 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | Direct |
46938,52087 46938 - CRAL/TRIO N-terminal domain 52087 - CRAL/TRIO domain | 0 | Direct |
55021,56534 55021 - ACT-like 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
63712,90112 63712 - Nicotinic receptor ligand binding domain-like 90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0 | Direct |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | Direct |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 0 | Direct |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
56436,56436 56436 - C-type lectin-like 56436 - C-type lectin-like | 0 | Direct |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | Direct |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | Direct |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
57184,57603 57184 - Growth factor receptor domain 57603 - FnI-like domain | 0 | Direct |
46689,46689 46689 - Homeodomain-like 46689 - Homeodomain-like | 0 | Direct |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | Direct |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | Direct |
54001,143791 54001 - Cysteine proteinases 143791 - DUSP-like | 0 | Direct |
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | Direct |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50729,50044 50729 - PH domain-like 50044 - SH3-domain | 0 | Direct |
50978,50998 50978 - WD40 repeat-like 50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | Direct |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | Direct |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
55785,55785 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
49265,49899 49265 - Fibronectin type III 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
100909,49899 100909 - IP3 receptor type 1 binding core, domain 2 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
75399,75399 75399 - Plakin repeat 75399 - Plakin repeat | 0 | Direct |
52743,49785 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | Direct |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
81324,81296 81324 - Voltage-gated potassium channels 81296 - E set domains | 0 | Direct |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | Direct |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57603,57603 57603 - FnI-like domain 57603 - FnI-like domain | 0 | Direct |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | Direct |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
51556,51338 51556 - Metallo-dependent hydrolases 51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0 | Direct |
54897,52743 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like | 0 | Direct |
90257,57997 90257 - Myosin rod fragments 57997 - Tropomyosin | 0 | Direct |
63825,57196 63825 - YWTD domain 57196 - EGF/Laminin | 0 | Direct |
52799,49562 52799 - (Phosphotyrosine protein) phosphatases II 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
48097,56112 48097 - Regulator of G-protein signaling, RGS 56112 - Protein kinase-like (PK-like) | 0 | Direct |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0 | Direct |
57196,90193 57196 - EGF/Laminin 90193 - Notch domain | 0 | Direct |
82109,82109 82109 - MIR domain 82109 - MIR domain | 0 | Direct |
49854,57196 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin | 0 | Direct |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | Direct |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0 | Direct |
49417,47719 49417 - p53-like transcription factors 47719 - p53 tetramerization domain | 0 | Direct |
52833,47616 52833 - Thioredoxin-like 47616 - GST C-terminal domain-like | 0 | Direct |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
82153,82153 82153 - FAS1 domain 82153 - FAS1 domain | 0 | Direct |
57850,57850 57850 - RING/U-box 57850 - RING/U-box | 0 | Direct |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | Direct |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | Direct |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0 | Direct |
50729,56112 50729 - PH domain-like 56112 - Protein kinase-like (PK-like) | 0 | Direct |
49758,47473 49758 - Calpain large subunit, middle domain (domain III) 47473 - EF-hand | 0 | Direct |
56112,47769 56112 - Protein kinase-like (PK-like) 47769 - SAM/Pointed domain | 0 | Direct |
48452,81901 48452 - TPR-like 81901 - HCP-like | 0 | Direct |
47655,49417 47655 - STAT 49417 - p53-like transcription factors | 0 | Direct |
49785,49785 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0 | Direct |
48371,48371 48371 - ARM repeat 48371 - ARM repeat | 0 | Direct |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
103575,48726 103575 - Plexin repeat 48726 - Immunoglobulin | 0 | Direct |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9024 | Inherited |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9855 | Inherited |
(show details)
Supra-domains annotated to this ZA term (Not in SPZA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | DIRECT |
50156,50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | DIRECT |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
57196,63825,57196 57196 - EGF/Laminin 63825 - YWTD domain 57196 - EGF/Laminin | 0 | DIRECT |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
47655,49417,55550 47655 - STAT 49417 - p53-like transcription factors 55550 - SH2 domain | 0 | DIRECT |
101912,103575,48726 101912 - Sema domain 103575 - Plexin repeat 48726 - Immunoglobulin | 0 | DIRECT |
49854,49785,49785 49854 - Spermadhesin, CUB domain 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
57184,52058,57184 57184 - Growth factor receptor domain 52058 - L domain-like 57184 - Growth factor receptor domain | 0 | DIRECT |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
47459,55785,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
90257,90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | DIRECT |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
82109,100909,49899 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57603,57603,57603 57603 - FnI-like domain 57603 - FnI-like domain 57603 - FnI-like domain | 0 | DIRECT |
57184,57184,57196 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49854,57196,49854 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57196,57196,90193 57196 - EGF/Laminin 57196 - EGF/Laminin 90193 - Notch domain | 0 | DIRECT |
49785,49785,49899 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
90193,90193,90193 90193 - Notch domain 90193 - Notch domain 90193 - Notch domain | 0 | DIRECT |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57196,57184,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
52743,49785,57184 52743 - Subtilisin-like 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain | 0 | DIRECT |
48726,49265,49265 48726 - Immunoglobulin 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
57184,57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54897,52743,49785 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | DIRECT |
69318,69179,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains 69179 - Integrin domains | 0 | DIRECT |
52058,57184,52058 52058 - L domain-like 57184 - Growth factor receptor domain 52058 - L domain-like | 0 | DIRECT |
49899,57196,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
57850,57850,57850 57850 - RING/U-box 57850 - RING/U-box 57850 - RING/U-box | 0 | DIRECT |
82109,82109,100909 82109 - MIR domain 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 | 0 | DIRECT |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
75399,75399,75399 75399 - Plakin repeat 75399 - Plakin repeat 75399 - Plakin repeat | 0 | DIRECT |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | DIRECT |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
69179,69179,69179 69179 - Integrin domains 69179 - Integrin domains 69179 - Integrin domains | 0 | DIRECT |
54928,54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
47031,50729,50729 47031 - Second domain of FERM 50729 - PH domain-like 50729 - PH domain-like | 0 | DIRECT |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
48092,47655,49417 48092 - Transcription factor STAT-4 N-domain 47655 - STAT 49417 - p53-like transcription factors | 0 | DIRECT |
57184,52058,49265 57184 - Growth factor receptor domain 52058 - L domain-like 49265 - Fibronectin type III | 0 | DIRECT |
82199,57667,57667 82199 - SET domain 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | DIRECT |
103575,81296,81296 103575 - Plexin repeat 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
46966,46966,47473 46966 - Spectrin repeat 46966 - Spectrin repeat 47473 - EF-hand | 0 | DIRECT |
57196,90193,90193 57196 - EGF/Laminin 90193 - Notch domain 90193 - Notch domain | 0 | DIRECT |
52058,49265,49265 52058 - L domain-like 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
49265,49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9297 | INHERITED FROM: synencephalon || medial longitudinal fasciculus || white matter |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9977 | INHERITED FROM: synencephalon || skeletal muscle cell || brain nucleus || brainstem || medial longitudinal fasciculus || white matter |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
50729,47473,51695 50729 - PH domain-like 47473 - EF-hand 51695 - PLC-like phosphodiesterases | 0 | Direct |
50156,50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | Direct |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
57196,63825,57196 57196 - EGF/Laminin 63825 - YWTD domain 57196 - EGF/Laminin | 0 | Direct |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
47655,49417,55550 47655 - STAT 49417 - p53-like transcription factors 55550 - SH2 domain | 0 | Direct |
101912,103575,48726 101912 - Sema domain 103575 - Plexin repeat 48726 - Immunoglobulin | 0 | Direct |
49854,49785,49785 49854 - Spermadhesin, CUB domain 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like | 0 | Direct |
57184,52058,57184 57184 - Growth factor receptor domain 52058 - L domain-like 57184 - Growth factor receptor domain | 0 | Direct |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
47459,55785,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
90257,90257,90257 90257 - Myosin rod fragments 90257 - Myosin rod fragments 90257 - Myosin rod fragments | 0 | Direct |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
82109,100909,49899 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57603,57603,57603 57603 - FnI-like domain 57603 - FnI-like domain 57603 - FnI-like domain | 0 | Direct |
57184,57184,57196 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49854,57196,49854 49854 - Spermadhesin, CUB domain 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | Direct |
57196,57196,90193 57196 - EGF/Laminin 57196 - EGF/Laminin 90193 - Notch domain | 0 | Direct |
49785,49785,49899 49785 - Galactose-binding domain-like 49785 - Galactose-binding domain-like 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
90193,90193,90193 90193 - Notch domain 90193 - Notch domain 90193 - Notch domain | 0 | Direct |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57196,57184,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
52743,49785,57184 52743 - Subtilisin-like 49785 - Galactose-binding domain-like 57184 - Growth factor receptor domain | 0 | Direct |
48726,49265,49265 48726 - Immunoglobulin 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
57184,57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54897,52743,49785 54897 - Protease propeptides/inhibitors 52743 - Subtilisin-like 49785 - Galactose-binding domain-like | 0 | Direct |
69318,69179,69179 69318 - Integrin alpha N-terminal domain 69179 - Integrin domains 69179 - Integrin domains | 0 | Direct |
52058,57184,52058 52058 - L domain-like 57184 - Growth factor receptor domain 52058 - L domain-like | 0 | Direct |
49899,57196,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
57850,57850,57850 57850 - RING/U-box 57850 - RING/U-box 57850 - RING/U-box | 0 | Direct |
82109,82109,100909 82109 - MIR domain 82109 - MIR domain 100909 - IP3 receptor type 1 binding core, domain 2 | 0 | Direct |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
75399,75399,75399 75399 - Plakin repeat 75399 - Plakin repeat 75399 - Plakin repeat | 0 | Direct |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
48726,49265,48726 48726 - Immunoglobulin 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | Direct |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | Direct |
69179,69179,69179 69179 - Integrin domains 69179 - Integrin domains 69179 - Integrin domains | 0 | Direct |
54928,54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
47031,50729,50729 47031 - Second domain of FERM 50729 - PH domain-like 50729 - PH domain-like | 0 | Direct |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
48092,47655,49417 48092 - Transcription factor STAT-4 N-domain 47655 - STAT 49417 - p53-like transcription factors | 0 | Direct |
57184,52058,49265 57184 - Growth factor receptor domain 52058 - L domain-like 49265 - Fibronectin type III | 0 | Direct |
82199,57667,57667 82199 - SET domain 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0 | Direct |
103575,81296,81296 103575 - Plexin repeat 81296 - E set domains 81296 - E set domains | 0 | Direct |
46966,46966,47473 46966 - Spectrin repeat 46966 - Spectrin repeat 47473 - EF-hand | 0 | Direct |
57196,90193,90193 57196 - EGF/Laminin 90193 - Notch domain 90193 - Notch domain | 0 | Direct |
52058,49265,49265 52058 - L domain-like 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
49265,49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.9297 | Inherited |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.9977 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
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