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Chorismate synthase, AroC superfamily
SCOP classification
Superfamily statistics
Functional annotation
General category | Metabolism |
Detailed category | Other enzymes |
Document: Function annotation of SCOP domain superfamilies
Enzyme Commission (EC) (show details)
Highlighted in gray are those with FDR_all>0.001
Document: EC annotation of SCOP domains
Enzyme Commission (EC) (show details)
Highlighted in gray are those with FDR_all>0.001
Document: EC annotation of SCOP domains
InterPro annotation
Cross references | IPR000453 SSF103263 Protein matches |
Abstract | Chorismate synthase catalyzes the last of the
seven steps in the
shikimate pathway which is used in prokaryotes, fungi and plants for the
biosynthesis of aromatic amino acids. It catalyzes the 1,4-trans elimination
of the phosphate group from 5-enolpyruvylshikimate-3-phosphate (EPSP) to form
chorismate which can then be used in phenylalanine, tyrosine or tryptophan
biosynthesis. Chorismate synthase requires the presence of a reduced flavin
mononucleotide (FMNH2 or FADH2) for its activity.
Chorismate synthase from various sources shows [1718979,
1837329] a high degree of sequence
conservation. It is a protein of about 360 to 400 amino-acid residues. |
InterPro database
PDBeMotif information about ligands, sequence and structure motifs
PDBeMotif resource
Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) ]
Internal database links
Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
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Alignments of sequences to 8 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
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Browse and view proteins in genomes which have
different domain combinations including a Chorismate synthase, AroC domain.
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Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
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Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
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There are 8 hidden Markov models representing the Chorismate synthase, AroC superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
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Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) · Internal database links ]
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