SUPERFAMILY 1.75 HMM library and genome assignments server

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Band 7/SPFH domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   EF-Ts domain-like [ 54712] (2)
Superfamily:   Band 7/SPFH domain [ 117892]
Families:   Band 7/SPFH domain [ 117893]

Superfamily statistics
Genomes (2,870) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 11,526 74,760 1
Proteins 11,256 73,574 1

Functional annotation
General category Processes_IC
Detailed category Ion metabolism and transport

Function annotation of SCOP domain superfamilies

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)integument phenotype0.03193Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal gland morphology0.1515Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal mammary gland morphology0.0006275InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism behavior variant0.000003392Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0.000006209Least InformativeDirect
Worm Phenotype (WP)mechanosensation variant0.0000002244InformativeDirect
Worm Phenotype (WP)growth rate variant0.0004903Highly InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)testis0Moderately InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0.717Least InformativeInherited
Plant ANatomical entity (PAN)root system0.7606Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue0.8804Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis0.9363Least InformativeInherited
Plant ANatomical entity (PAN)primordium0.00000005275InformativeDirect
Plant ANatomical entity (PAN)root tip0.000001205InformativeDirect
Plant ANatomical entity (PAN)cultured plant cell0.000000000006098Highly InformativeDirect
Plant ANatomical entity (PAN)vegetative shoot apex0.000000001568Highly InformativeDirect
Plant ANatomical entity (PAN)phyllome primordium0.000000001905Highly InformativeDirect
Plant ANatomical entity (PAN)root meristem0.000000004627Highly InformativeDirect
Plant ANatomical entity (PAN)trichome0.00000006757Highly InformativeDirect

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Band 7/SPFH domain domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Band 7/SPFH domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]