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Home > SCOP hierarchy > SOCS box-like superfamily

SOCS box-like superfamily

SCOP classification

Root:	SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:	All alpha proteins [ 46456] (284)
Fold:	SOCS box-like [ 158234]
Superfamily:	SOCS box-like [ 158235]
Families:	SOCS box-like [ 158236] (2)

Superfamily statistics

	Genomes (144)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	2,851	7,179	2
Proteins	2,850	7,177	2

Functional annotation
Document: Function annotation of SCOP domain superfamilies

Disease Ontology (DO)

(show details)

	DO term	FDR (all)	SDDO level	Annotation (direct or inherited)
Disease Ontology (DO)	organ system cancer	0.261	Least Informative	Inherited
Disease Ontology (DO)	disease by infectious agent	0.004594	Moderately Informative	Inherited
Disease Ontology (DO)	hematologic cancer	0.07582	Moderately Informative	Inherited
Disease Ontology (DO)	primary bacterial infectious disease	0.002102	Informative	Inherited
Disease Ontology (DO)	myeloid leukemia	0.1328	Informative	Inherited
Disease Ontology (DO)	in situ carcinoma	0.00003832	Highly Informative	Direct
Disease Ontology (DO)	tuberculosis	0.0006095	Highly Informative	Direct

Document: DO annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)

	XA term	FDR (all)	SDXA level	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	tail	0.0007349	Informative	Direct

Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Disease Ontology (DO) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a SOCS box-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the SOCS box-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Disease Ontology (DO) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]