SUPERFAMILY 1.75 HMM library and genome assignments server

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SNF-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   SNF-like [ 161069]
Superfamily:   SNF-like [ 161070]
Family:   SNF-like [ 161071]

Family statistics
Genomes (1,218) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 4,062 22,169 2
Proteins 4,056 22,113 2

Disease Ontology (DO)

show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)disease of mental health0.003133Moderately InformativeInherited
Disease Ontology (DO)substance dependence0.00006605InformativeDirect
Disease Ontology (DO)developmental disorder of mental health0.08129InformativeInherited
Disease Ontology (DO)bipolar disorder0.00007358Highly InformativeDirect
Disease Ontology (DO)specific developmental disorder0.0003945Highly InformativeDirect
Disease Ontology (DO)drug dependence0.000653Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.03699Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.03886Least InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.009938Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal amino acid level0.00002211InformativeDirect
Mammalian Phenotype (MP)abnormal behavioral response to xenobiotic0.00004846InformativeDirect
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.0004705InformativeDirect
Mammalian Phenotype (MP)abnormal learning/memory/conditioning0.003363InformativeInherited
Mammalian Phenotype (MP)abnormal emotion/affect behavior0.01631InformativeInherited
Mammalian Phenotype (MP)abnormal associative learning0.00008126Highly InformativeDirect
Mammalian Phenotype (MP)abnormal response to novelty0.06972Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism behavior variant0.0003402Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0.1659Least InformativeInherited
Worm Phenotype (WP)movement variant0.000002097Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.00001191Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.00001227Moderately InformativeDirect
Worm Phenotype (WP)chemical response variant0.2699Moderately InformativeInherited
Worm Phenotype (WP)head movement variant0InformativeDirect
Worm Phenotype (WP)body posture variant6.263e-16InformativeDirect
Worm Phenotype (WP)foraging behavior variant0.0000000000000561InformativeDirect
Worm Phenotype (WP)locomotor coordination variant0.0000000000003025InformativeDirect
Worm Phenotype (WP)forward locomotion variant0.000006161InformativeDirect
Worm Phenotype (WP)drug hypersensitive0.0001311InformativeDirect
Worm Phenotype (WP)velocity of movement variant0.0002141InformativeDirect
Worm Phenotype (WP)small0.5697InformativeInherited
Worm Phenotype (WP)locomotion reduced1InformativeInherited
Worm Phenotype (WP)coiling frequency variant0.00000000000005268Highly InformativeDirect
Worm Phenotype (WP)forward point velocity variant0.0000000000001744Highly InformativeDirect
Worm Phenotype (WP)backward point velocity variant0.0000000000002422Highly InformativeDirect
Worm Phenotype (WP)fat0.0000004226Highly InformativeDirect
Worm Phenotype (WP)pausing variant0.0000007571Highly InformativeDirect
Worm Phenotype (WP)short0.000007812Highly InformativeDirect
Worm Phenotype (WP)roaming variant0.008649Highly InformativeInherited
Worm Phenotype (WP)foraging hyperactive0.01993Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) ]

Internal database links

Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Superfamily level     Family level

Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Superfamily level

Browse and view proteins in genomes which have different domain combinations including a SNF-like domain.

Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Internal database links ]