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Home > SCOP hierarchy > Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain superfamily

Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain superfamily

SCOP classification

Root:	SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:	All alpha proteins [ 46456] (284)
Fold:	Spectrin repeat-like [ 46965] (16)
Superfamily:	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain [ 46977]
Families:	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain [ 46978] (4)

Superfamily statistics

	Genomes (2,703)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	5,448	41,543	10
Proteins	5,444	41,527	10

Functional annotation

General category	Metabolism
Detailed category	Redox

Document: Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)

	EC term	FDR (all)	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	Oxidoreductases	0	Least Informative	Direct
Enzyme Commission (EC)	Acting on the CH-CH group of donors	0	Moderately Informative	Direct
Enzyme Commission (EC)	With oxygen as acceptor	0	Informative	Direct
Enzyme Commission (EC)	With other acceptors	0.000000000001972	Informative	Direct
Enzyme Commission (EC)	Succinate dehydrogenase	0	Highly Informative	Direct
Enzyme Commission (EC)	Succinate dehydrogenase (ubiquinone)	0	Highly Informative	Direct
Enzyme Commission (EC)	L-aspartate oxidase	0	Highly Informative	Direct

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)

	AP term	FDR (all)	SDAP level	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	guard cell	0	Least Informative	Direct
Plant ANatomical entity (PAN)	root system	0	Least Informative	Direct

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)

	EC term	FDR (all)	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Oxidoreductases	0	Least Informative	Direct
Enzyme Commission (EC)	Acting on the CH-NH(2) group of donors	0	Informative	Direct
Enzyme Commission (EC)	With a quinone or related compound as acceptor	0	Highly Informative	Direct
Enzyme Commission (EC)	With oxygen as acceptor	0	Highly Informative	Direct

Document: EC annotation of SCOP domains

InterPro annotation

Cross references IPR015939 SSF46977 Protein matches

Abstract
This entry represents a domain with a spectrin-repeat-like fold consisting of three helices in a closed bundle with a left-handed twist. This domain is found in the succinate dehydrogenase/fumarate reductase oxidoreductase family of proteins, such as:

L-aspartate oxidase , a flavoenzyme component of the bacterial quinolinate synthase system that catalyses the conversion of L-aspartate to oxaloacetate, the first step in the de novo biosynthesis of NAD+ [ PubMed 11863440, PubMed 10425677].

Fumarate reductase, which is part of the quinol-fumarate reductase (QFR) respiratory complex that catalyses the terminal step of anaerobic respiration when fumarate acts as the terminal electron acceptor [ PubMed 11850430].

Succinate dehydrogenase (SQR), an iron-sulphur flavoenzyme from bacteria that is analogous to the mitochondrial respiratory complex II, forming part of the electron transport pathway from the electron acceptor (succinate) to the terminal donor (ubiquinone) [ PubMed 12560550].

Adenylylsulphate reductase A subunit , an iron-sulphur flavoenzyme that catalyses the reversible reduction of adenosine-5'-phosphate (APS) to sulphite and AMP [ PubMed 11842205].

InterPro database

PDBeMotif information about ligands, sequence and structure motifs

Cross references

PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]