SUPERFAMILY 1.75 HMM library and genome assignments server

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Armadillo repeat family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   ARM repeat [ 48371] (23)
Family:   Armadillo repeat [ 48372] (6)

Family statistics
Genomes (504) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 4,511 12,514 31
Proteins 4,468 12,443 31

Human Phenotype (HP)

show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the face0Least InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.01705Least InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.2515Moderately InformativeInherited
Mammalian Phenotype (MP)embryonic lethality prior to organogenesis0.7161InformativeInherited
Mammalian Phenotype (MP)embryonic lethality between implantation and somite formation, complete penetrance0.0004079Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.00003484Least InformativeDirect
Worm Phenotype (WP)cell development variant0.0007531Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.003939Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.09086Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.000000003986Moderately InformativeDirect
Worm Phenotype (WP)cell organization biogenesis variant0.0000001729Moderately InformativeDirect
Worm Phenotype (WP)pattern of transgene expression variant0.0004525Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0.002589Moderately InformativeInherited
Worm Phenotype (WP)protein expression variant0.01304Moderately InformativeInherited
Worm Phenotype (WP)organ system development variant0.05081Moderately InformativeInherited
Worm Phenotype (WP)organism stress response variant0.07677Moderately InformativeInherited
Worm Phenotype (WP)cell death variant0.2786Moderately InformativeInherited
Worm Phenotype (WP)embryonic cell organization biogenesis variant0.000000005395InformativeDirect
Worm Phenotype (WP)cytoskeleton organization biogenesis variant0.00000009027InformativeDirect
Worm Phenotype (WP)pattern protein expression variant0.0000005354InformativeDirect
Worm Phenotype (WP)germ cell physiology variant0.00002222InformativeDirect
Worm Phenotype (WP)brood size variant0.00005482InformativeDirect
Worm Phenotype (WP)hermaphrodite physiology variant0.0001129InformativeDirect
Worm Phenotype (WP)cell number increased0.0001338InformativeDirect
Worm Phenotype (WP)endocytic transport defect0.0003848InformativeDirect
Worm Phenotype (WP)sensillum morphology variant0.003904InformativeInherited
Worm Phenotype (WP)epithelial system development variant0.02683InformativeInherited
Worm Phenotype (WP)organism pathogen response variant0.153InformativeInherited
Worm Phenotype (WP)developmental morphology variant0.0000006557Highly InformativeDirect
Worm Phenotype (WP)RNAi resistant0.000001689Highly InformativeDirect
Worm Phenotype (WP)maintenance of gene silencing variant0.000002933Highly InformativeDirect
Worm Phenotype (WP)epithelial development variant0.000009783Highly InformativeDirect
Worm Phenotype (WP)pericellular component physiology variant0.00002153Highly InformativeDirect
Worm Phenotype (WP)pronucleus centrosomes defective early emb0.00004463Highly InformativeDirect
Worm Phenotype (WP)cell polarity variant0.0002709Highly InformativeDirect
Worm Phenotype (WP)epithelial system physiology variant0.0003474Highly InformativeDirect
Worm Phenotype (WP)dye filling defect0.0003864Highly InformativeDirect
Worm Phenotype (WP)no induction of antimicrobial peptide expression after infection0.0004471Highly InformativeDirect
Worm Phenotype (WP)cell secretion variant0.002185Highly InformativeInherited
Worm Phenotype (WP)cell number decreased0.03647Highly InformativeInherited
Worm Phenotype (WP)spindle position orientation defective early emb0.8845Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details) Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)somatic cell0Least InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0.000000003401Least InformativeDirect
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0InformativeDirect
Enzyme Commission (EC)HECT-type E3 ubiquitin transferase0.0000000728Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Superfamily level     Family level

Alignments of sequences to 75 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Superfamily level

Browse and view proteins in genomes which have different domain combinations including a ARM repeat domain.

Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]