HSP20 family

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: All beta proteins [ 48724] (174)
• Fold: HSP20-like chaperones [ 49763]
• Superfamily: HSP20-like chaperones [ 49764] (4)
• Family: HSP20 [ 49765]

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Family statistics

	Genomes (71)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	734	1,433	3
Proteins	732	1,426	3

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Worm Phenotype (WP)

Highlighted in gray are those with FDR_all>0.001

	WP term	FDR (all)	IC level	SDWP level	Annotation (direct or inherited)
Worm Phenotype (WP)	growth variant	0	0.3438	--	DIRECT
Worm Phenotype (WP)	postembryonic development variant	0	0.269	--	DIRECT
Worm Phenotype (WP)	embryonic lethal	0	0.046	--	DIRECT
Worm Phenotype (WP)	lethal	0	0.00521	--	DIRECT
Worm Phenotype (WP)	fertility variant	0	0.05937	--	DIRECT
Worm Phenotype (WP)	transgene expression variant	0	0.773	--	DIRECT
Worm Phenotype (WP)	behavior variant	0	0.6859	--	DIRECT
Worm Phenotype (WP)	development variant	0	0.001482	--	DIRECT
Worm Phenotype (WP)	organism development variant	0	0.00297	--	DIRECT
Worm Phenotype (WP)	organ system physiology variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	organism physiology variant	0	0.1342	--	DIRECT
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	0.1444	--	DIRECT
Worm Phenotype (WP)	reproductive system physiology variant	0	0.05515	--	DIRECT
Worm Phenotype (WP)	locomotion variant	0	1.053	--	DIRECT
Worm Phenotype (WP)	maternal sterile	0	0.1213	--	DIRECT
Worm Phenotype (WP)	hermaphrodite sterile	0	0.1203	--	DIRECT
Worm Phenotype (WP)	gene expression variant	0	0.6256	--	DIRECT
Worm Phenotype (WP)	embryonic development variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	larval development variant	0	0.4322	--	DIRECT
Worm Phenotype (WP)	hermaphrodite fertility variant	0	0.0947	--	DIRECT
Worm Phenotype (WP)	developmental growth variant	0	0.4991	--	DIRECT
Worm Phenotype (WP)	larval growth variant	0	0.4991	--	DIRECT
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	0.1193	--	DIRECT
Worm Phenotype (WP)	fertility reduced	0	0.06449	--	DIRECT
Worm Phenotype (WP)	protein aggregation variant	0.00000005822	1.087	--	DIRECT
Worm Phenotype (WP)	transgene subcellular localization variant	0.000004069	1.125	--	DIRECT
Worm Phenotype (WP)	protein interaction variant	0.00006646	1.078	--	DIRECT
Worm Phenotype (WP)	physiology variant	1	0	--	INHERITED FROM: hermaphrodite fertility variant || developmental growth variant || organism metabolism processing variant || protein protein interaction variant || reproductive system physiology variant || transgene expression variant || gene expression variant || pathogen susceptibility increased || organism homeostasis metabolism variant || movement variant || lethal || larval development variant || protein interaction variant || organism physiology variant || transgene subcellular localization variant || development variant || organism pathogen response variant || hermaphrodite sterile || growth variant || hermaphrodite fertility reduced || embryonic development variant || embryonic lethal || larval growth variant || fertility variant || behavior variant || protein aggregation variant || postembryonic development variant || larval arrest || organ system physiology variant || organism behavior variant || maternal sterile || organism development variant || locomotion variant || fertility reduced
Worm Phenotype (WP)	sterile	1	0.1135	--	INHERITED FROM: hermaphrodite sterile || maternal sterile
Worm Phenotype (WP)	organism metabolism processing variant	0	0.4899	Least Informative	DIRECT
Worm Phenotype (WP)	larval arrest	0	0.4991	Least Informative	DIRECT
Worm Phenotype (WP)	organism behavior variant	0	0.6859	Least Informative	DIRECT
Worm Phenotype (WP)	organism environmental stimulus response variant	0.1216	0.6614	Least Informative	INHERITED FROM: pathogen susceptibility increased || organism pathogen response variant
Worm Phenotype (WP)	movement variant	0	1.02	Moderately Informative	DIRECT
Worm Phenotype (WP)	protein protein interaction variant	0.00000007086	1.078	Moderately Informative	DIRECT
Worm Phenotype (WP)	organism stress response variant	0.01018	0.9693	Moderately Informative	INHERITED FROM: pathogen susceptibility increased || organism pathogen response variant
Worm Phenotype (WP)	pattern of transgene expression variant	0.1137	0.9833	Moderately Informative	INHERITED FROM: transgene subcellular localization variant
Worm Phenotype (WP)	organism pathogen response variant	0.0001969	1.468	Informative	DIRECT
Worm Phenotype (WP)	pathogen susceptibility increased	0.0000006584	2.07	Highly Informative	DIRECT

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Arabidopsis Plant Ontology (AP)

Highlighted in gray are those with FDR_all>0.001

	AP term	FDR (all)	IC level	SDAP level	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	collective plant structure	0	0.01555	--	DIRECT
Plant ANatomical entity (PAN)	shoot system	0	0.05272	--	DIRECT
Plant ANatomical entity (PAN)	plant cell	0.7873	0.1228	--	INHERITED FROM: pollen tube cell
Plant ANatomical entity (PAN)	plant structure	1	0	--	INHERITED FROM: collective plant structure || shoot system || pollen tube cell
Plant ANatomical entity (PAN)	collective plant organ structure	1	0.03998	--	INHERITED FROM: shoot system
Plant ANatomical entity (PAN)	pollen tube cell	0.000617	1.454	Informative	DIRECT
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	0	0.0371	--	DIRECT
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0	0.0282	--	DIRECT
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	0.02956	--	INHERITED FROM: reproductive shoot system development stage

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UniProtKB KeyWords (KW)

Highlighted in gray are those with FDR_all>0.001

	KW term	FDR (all)	IC level	SDKW level	Annotation (direct or inherited)
Biological process	Stress response	0	1.114	Moderately Informative	DIRECT

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