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Home > SCOP hierarchy > Bacterial luciferase-like superfamily

Bacterial luciferase-like superfamily

SCOP classification

Root:	SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:	Alpha and beta proteins (a/b) [ 51349] (147)
Fold:	TIM beta/alpha-barrel [ 51350] (33)
Superfamily:	Bacterial luciferase-like [ 51679] (4)
Families:	Bacterial luciferase (alkanal monooxygenase) [ 51680] (2)
	Non-fluorescent flavoprotein (luxF, FP390) [ 51683]
	F420 dependent oxidoreductases [ 51687] (2)
	Ssud-like monoxygenases [ 82275] (2)

Superfamily statistics

	Genomes (1,604)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	11,055	123,993	11
Proteins	11,046	123,878	11

Functional annotation

General category	Metabolism
Detailed category	Other enzymes

Document: Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)

	EC term	FDR (all)	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	Oxidoreductases	0	Least Informative	Direct
Enzyme Commission (EC)	Acting on paired donors, with incorporation or red	0	Moderately Informative	Direct
Enzyme Commission (EC)	Acting on the CH-NH group of donors	0.4211	Moderately Informative	Inherited
Enzyme Commission (EC)	With other acceptors	0	Informative	Direct
Enzyme Commission (EC)	With reduced flavin or flavoprotein as one donor,	0	Highly Informative	Direct

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)

	EC term	FDR (all)	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Oxidoreductases	0	Least Informative	Direct
Enzyme Commission (EC)	Acting on the CH-OH group of donors	1	Moderately Informative	Inherited
Enzyme Commission (EC)	Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporate	0	Informative	Direct
Enzyme Commission (EC)	Acting on the CH-NH group of donors	0.4403	Informative	Inherited
Enzyme Commission (EC)	Miscellaneous	0.000000000000001518	Highly Informative	Direct
Enzyme Commission (EC)	With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	0.000000000004322	Highly Informative	Direct

Document: EC annotation of SCOP domains

InterPro annotation

Cross references IPR011251 SSF51679 Protein matches

Abstract
Bacterial luciferase is a flavin monooxygenase that catalyses the oxidation of long-chain aldehydes and releases energy in the form of visible light, and which uses flavin as a substrate rather than a cofactor [ PubMed 8703001]. Bacterial luciferase is an alpha/beta (LuxA/LuxB) heterodimer, where each individual subunit folds into a single TIM (beta/alpha)8-barrel domain. There are structural similarities between bacterial luciferase and nonfluorescent flavoproteins (LuxF, FP390), alkanesulphonate monooxygenase (SsuD), and coenzyme F420-dependent terahydromethanopterin reductase, which make up clearly related families with somewhat different folds [ PubMed 7776372, PubMed 12445781, PubMed 10891279].

More information about these proteins can be found at Protein of the Month: Luciferase.

InterPro database

PDBeMotif information about ligands, sequence and structure motifs

Cross references

PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 17 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Bacterial luciferase-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 17 hidden Markov models representing the Bacterial luciferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) · Internal database links ]