6-phosphogluconate dehydrogenase-like, N-terminal domain family

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: Alpha and beta proteins (a/b) [ 51349] (147)
• Fold: NAD(P)-binding Rossmann-fold domains [ 51734]
• Superfamily: NAD(P)-binding Rossmann-fold domains [ 51735] (12)
• Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain [ 51868] (18)

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Family statistics

	Genomes (3,008)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	12,732	96,239	37
Proteins	12,729	96,215	37

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	With other known acceptors	0	2.44	--	DIRECT
Enzyme Commission (EC)	5,10-methenyltetrahydromethanopterin hydrogenase	0	2.44	--	DIRECT
Enzyme Commission (EC)	Glycerol-3-phosphate dehydrogenase (NAD(P)(+))	0	2.44	--	DIRECT
Enzyme Commission (EC)	3-hydroxybutyryl-CoA epimerase	0	2.264	--	DIRECT
Enzyme Commission (EC)	Ketol-acid reductoisomerase	0	2.44	--	DIRECT
Enzyme Commission (EC)	Acting on the CH-OH group of donors	0	0.935	--	DIRECT
Enzyme Commission (EC)	Carbon-oxygen lyases	0	0.8221	--	DIRECT
Enzyme Commission (EC)	3-hydroxyacyl-CoA dehydrogenase	0	2.264	--	DIRECT
Enzyme Commission (EC)	Phosphogluconate dehydrogenase (decarboxylating)	0	2.44	--	DIRECT
Enzyme Commission (EC)	Pyrroline-5-carboxylate reductase	0	2.44	--	DIRECT
Enzyme Commission (EC)	Dodecenoyl-CoA isomerase	0	2.264	--	DIRECT
Enzyme Commission (EC)	Prephenate dehydrogenase	0	2.44	--	DIRECT
Enzyme Commission (EC)	Acting on hydroxy acids and derivatives	0	2.264	--	DIRECT
Enzyme Commission (EC)	Enoyl-CoA hydratase	0	2.264	--	DIRECT
Enzyme Commission (EC)	Glycerol-3-phosphate dehydrogenase (NAD(+))	0.000000000000001381	2.44	--	DIRECT
Enzyme Commission (EC)	UDP-glucose 6-dehydrogenase	0.0000000000008398	2.264	--	DIRECT
Enzyme Commission (EC)	Tagaturonate reductase	0.000002422	2.44	--	DIRECT
Enzyme Commission (EC)	Mannitol 2-dehydrogenase	0.0000207	2.44	--	DIRECT
Enzyme Commission (EC)	UDP-N-acetyl-D-mannosamine dehydrogenase	0.0000424	2.264	--	DIRECT
Enzyme Commission (EC)	3-hydroxyisobutyrate dehydrogenase	0.00004719	2.44	--	DIRECT
Enzyme Commission (EC)	3-hydroxybutyryl-CoA dehydrogenase	0.0001788	2.44	--	DIRECT
Enzyme Commission (EC)	L-gulonate 3-dehydrogenase	0.0003684	2.44	--	DIRECT
Enzyme Commission (EC)	GDP-mannose 6-dehydrogenase	0.0007611	2.264	--	DIRECT
Enzyme Commission (EC)	Acting on the CH-NH group of donors	1	1.279	--	INHERITED FROM: Pyrroline-5-carboxylate reductase || With NAD(+) or NADP(+) as acceptor
Enzyme Commission (EC)	Oxidoreductases	0	0.3212	Least Informative	DIRECT
Enzyme Commission (EC)	Isomerases	0.000000000000354	0.6881	Least Informative	DIRECT
Enzyme Commission (EC)	Lyases	0.01169	0.4956	Least Informative	INHERITED FROM: Carbon-oxygen lyases || Enoyl-CoA hydratase || Hydro-lyases
Enzyme Commission (EC)	Hydro-lyases	0	0.9853	Moderately Informative	DIRECT
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	0.9853	Moderately Informative	DIRECT
Enzyme Commission (EC)	Intramolecular oxidoreductases	0.00000000001739	1.118	Moderately Informative	DIRECT
Enzyme Commission (EC)	Acting on the CH-CH group of donors	1	1.185	Moderately Informative	INHERITED FROM: Prephenate dehydrogenase
Enzyme Commission (EC)	Racemases and epimerases	0	1.379	Informative	DIRECT
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	1.511	Informative	DIRECT
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0.01378	1.399	Informative	INHERITED FROM: Prephenate dehydrogenase
Enzyme Commission (EC)	Transposing C==C bonds	0	1.838	Highly Informative	DIRECT
Enzyme Commission (EC)	Acting on hydrogen as donor	0.0009595	2.139	Highly Informative	DIRECT

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Worm Phenotype (WP)

Highlighted in gray are those with FDR_all>0.001

	WP term	FDR (all)	IC level	SDWP level	Annotation (direct or inherited)
Worm Phenotype (WP)	embryonic lethal	0	0.046	--	DIRECT
Worm Phenotype (WP)	lethal	0	0.00521	--	DIRECT
Worm Phenotype (WP)	fertility variant	0	0.05937	--	DIRECT
Worm Phenotype (WP)	development variant	0	0.001482	--	DIRECT
Worm Phenotype (WP)	morphology variant	0	0.046	--	DIRECT
Worm Phenotype (WP)	organism development variant	0	0.00297	--	DIRECT
Worm Phenotype (WP)	organ system physiology variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	reproductive system physiology variant	0	0.05515	--	DIRECT
Worm Phenotype (WP)	hermaphrodite sterile	0	0.1203	--	DIRECT
Worm Phenotype (WP)	embryonic development variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	hermaphrodite fertility variant	0	0.0947	--	DIRECT
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	0.1193	--	DIRECT
Worm Phenotype (WP)	fertility reduced	0	0.06449	--	DIRECT
Worm Phenotype (WP)	lipid metabolism variant	0.00001128	1.337	--	DIRECT
Worm Phenotype (WP)	organism homeostasis metabolism variant	0.261	0.1444	--	INHERITED FROM: lipid metabolism variant || fat content variant
Worm Phenotype (WP)	organism physiology variant	0.2793	0.1342	--	INHERITED FROM: lipid metabolism variant || fat content variant
Worm Phenotype (WP)	physiology variant	1	0	--	INHERITED FROM: hermaphrodite fertility variant || fat content variant || reproductive system physiology variant || lethal || development variant || hermaphrodite sterile || hermaphrodite fertility reduced || lipid metabolism variant || embryonic development variant || embryonic lethal || fertility variant || organ system physiology variant || organism development variant || fertility reduced
Worm Phenotype (WP)	sterile	1	0.1135	--	INHERITED FROM: hermaphrodite sterile
Worm Phenotype (WP)	organism metabolism processing variant	0.1037	0.4899	Least Informative	INHERITED FROM: lipid metabolism variant || fat content variant
Worm Phenotype (WP)	fat content variant	0.000004311	1.407	Informative	DIRECT

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Yeast Phenotype (YP)

Highlighted in gray are those with FDR_all>0.001

	YP term	FDR (all)	IC level	SDYP level	Annotation (direct or inherited)
Yeast Phenotype (YP)	cellular processes	0	0.09186	--	DIRECT

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Fly Phenotype (FP)

Highlighted in gray are those with FDR_all>0.001

	FP term	FDR (all)	IC level	SDFP level	Annotation (direct or inherited)
Fly Phenotype (FP)	viable	0	0.6613	Least Informative	DIRECT
Fly Phenotype (FP)	fertile	0	0.8805	Moderately Informative	DIRECT

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Fly Anatomy (FA)

Highlighted in gray are those with FDR_all>0.001

	FA term	FDR (all)	IC level	SDFA level	Annotation (direct or inherited)
Fly Anatomy (FA)	organism	0	0.06695	--	DIRECT
Fly Anatomy (FA)	organ system	0	0.1823	--	DIRECT
Fly Anatomy (FA)	multicellular structure	0	0.008955	--	DIRECT
Fly Anatomy (FA)	anatomical structure	1	0	--	INHERITED FROM: organism || organ system || multicellular structure
Fly Anatomy (FA)	material anatomical entity	1	0	--	INHERITED FROM: organ system || multicellular structure || organism

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Xenopus Anatomy (XA)

Highlighted in gray are those with FDR_all>0.001

	XA term	FDR (all)	IC level	SDXA level	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	anatomical structure	0	0	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical group	0	0.1408	--	DIRECT
Xenopus ANatomical entity (XAN)	organism subdivision	0	0.1679	--	DIRECT
Xenopus ANatomical entity (XAN)	compound organ	0	0.2177	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical region	0	0.1803	--	DIRECT
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	0.1131	--	DIRECT
Xenopus ANatomical entity (XAN)	whole organism	1	0.0884	--	INHERITED FROM: anatomical group || cavitated compound organ || multicellular anatomical structure || compound organ || anatomical region || organism subdivision
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	0.2685	Least Informative	DIRECT
Xenopus DEvelopment stage (XDE)	NF stage	0	0.01895	--	DIRECT

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Arabidopsis Plant Ontology (AP)

Highlighted in gray are those with FDR_all>0.001

	AP term	FDR (all)	IC level	SDAP level	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	whole plant	0	0.3507	--	DIRECT
Plant ANatomical entity (PAN)	cauline leaf	0	0.6042	--	DIRECT
Plant ANatomical entity (PAN)	guard cell	0	0.2279	--	DIRECT
Plant ANatomical entity (PAN)	stomatal complex	0	0.2279	--	DIRECT
Plant ANatomical entity (PAN)	epidermal cell	0	0.2152	--	DIRECT
Plant ANatomical entity (PAN)	epidermis	0	0.2046	--	DIRECT
Plant ANatomical entity (PAN)	phyllome	0	0.3234	--	DIRECT
Plant ANatomical entity (PAN)	shoot epidermis	0	0.2224	--	DIRECT
Plant ANatomical entity (PAN)	leaf lamina base	0	0.6245	--	DIRECT
Plant ANatomical entity (PAN)	plant cell	0	0.1228	--	DIRECT
Plant ANatomical entity (PAN)	shoot system	0	0.05272	--	DIRECT
Plant ANatomical entity (PAN)	portion of plant tissue	0	0.1621	--	DIRECT
Plant ANatomical entity (PAN)	plant organ	0	0.2391	--	DIRECT
Plant ANatomical entity (PAN)	sporophyll	0	0.3985	--	DIRECT
Plant ANatomical entity (PAN)	stamen	0	0.5171	--	DIRECT
Plant ANatomical entity (PAN)	carpel	0	0.5117	--	DIRECT
Plant ANatomical entity (PAN)	flower	0	0.3446	--	DIRECT
Plant ANatomical entity (PAN)	pedicel	0	0.5373	--	DIRECT
Plant ANatomical entity (PAN)	perianth	0	0.4476	--	DIRECT
Plant ANatomical entity (PAN)	corolla	0	0.4893	--	DIRECT
Plant ANatomical entity (PAN)	calyx	0	0.4728	--	DIRECT
Plant ANatomical entity (PAN)	inflorescence branch	0	0.5373	--	DIRECT
Plant ANatomical entity (PAN)	cotyledon	0	0.6432	--	DIRECT
Plant ANatomical entity (PAN)	petiole	0	0.6385	--	DIRECT
Plant ANatomical entity (PAN)	inflorescence axis	0	0.5373	--	DIRECT
Plant ANatomical entity (PAN)	leaf apex	0	0.5999	--	DIRECT
Plant ANatomical entity (PAN)	stem internode	0	0.5373	--	DIRECT
Plant ANatomical entity (PAN)	cardinal organ part	0	0.4385	--	DIRECT
Plant ANatomical entity (PAN)	plant axis	0	0.3257	--	DIRECT
Plant ANatomical entity (PAN)	collective phyllome structure	0	0.3837	--	DIRECT
Plant ANatomical entity (PAN)	shoot axis	0	0.3985	--	DIRECT
Plant ANatomical entity (PAN)	leaf	0	0.4282	--	DIRECT
Plant ANatomical entity (PAN)	lamina	0	0.6199	--	DIRECT
Plant ANatomical entity (PAN)	reproductive shoot system	0	0.3304	--	DIRECT
Plant ANatomical entity (PAN)	shoot epidermal cell	0	0.227	--	DIRECT
Plant ANatomical entity (PAN)	multi-tissue plant structure	0	0.2335	--	DIRECT
Plant ANatomical entity (PAN)	collective plant structure	0	0.01555	--	DIRECT
Plant ANatomical entity (PAN)	cardinal part of multi-tissue plant structure	0	0.437	--	DIRECT
Plant ANatomical entity (PAN)	plant structure	1	0	--	INHERITED FROM: perianth || sporophyll || calyx || inflorescence axis || flower || lamina || collective plant structure || plant embryo || leaf || shoot internode || phyllome || cardinal organ part || multi-tissue plant structure || microsporophyll || guard cell || megasporophyll || cauline leaf || reproductive shoot system || shoot apex || leaf apex || leaf lamina base || branch || collective leaf structure || stem internode || inflorescence branch || shoot system || portion of plant tissue || stomatal complex || plant organ || stem || whole plant || epidermis || inflorescence || cardinal part of multi-tissue plant structure || petiole || stalk || gynoecium || vascular leaf || sepal || epidermal cell || leaf lamina || shoot epidermal cell || corolla || plant axis || collective phyllome structure || petal || plant cell || carpel || seed || shoot epidermis || phyllome apex || cotyledon || stamen || shoot axis || pedicel || androecium
Plant ANatomical entity (PAN)	collective plant organ structure	1	0.03998	--	INHERITED FROM: inflorescence axis || calyx || flower || sporophyll || inflorescence || perianth || stem || leaf || phyllome || shoot internode || sepal || vascular leaf || gynoecium || petiole || petal || reproductive shoot system || shoot apex || leaf apex || carpel || collective phyllome structure || guard cell || megasporophyll || cauline leaf || microsporophyll || leaf lamina || shoot epidermal cell || corolla || pedicel || androecium || stomatal complex || phyllome apex || cotyledon || stamen || stem internode || inflorescence branch || shoot axis || shoot system || leaf lamina base || collective leaf structure || branch || shoot epidermis
Plant ANatomical entity (PAN)	phyllome lamina	1	0.6199	--	INHERITED FROM: leaf lamina base || leaf lamina
Plant ANatomical entity (PAN)	organ lamina	1	0.6199	--	INHERITED FROM: leaf lamina base || leaf lamina
Plant ANatomical entity (PAN)	shoot apex	0	0.481	Least Informative	DIRECT
Plant ANatomical entity (PAN)	shoot internode	0	0.5373	Least Informative	DIRECT
Plant ANatomical entity (PAN)	plant embryo	0	0.4978	Least Informative	DIRECT
Plant ANatomical entity (PAN)	seed	0	0.5189	Least Informative	DIRECT
Plant ANatomical entity (PAN)	vascular leaf	0	0.437	Least Informative	DIRECT
Plant ANatomical entity (PAN)	megasporophyll	0	0.5117	Least Informative	DIRECT
Plant ANatomical entity (PAN)	microsporophyll	0	0.4415	Least Informative	DIRECT
Plant ANatomical entity (PAN)	sepal	0	0.4728	Least Informative	DIRECT
Plant ANatomical entity (PAN)	petal	0	0.4893	Least Informative	DIRECT
Plant ANatomical entity (PAN)	stem	0	0.4777	Least Informative	DIRECT
Plant ANatomical entity (PAN)	inflorescence	0	0.4859	Least Informative	DIRECT
Plant ANatomical entity (PAN)	androecium	0	0.5153	Least Informative	DIRECT
Plant ANatomical entity (PAN)	gynoecium	0	0.5082	Least Informative	DIRECT
Plant ANatomical entity (PAN)	leaf lamina	0	0.6199	Least Informative	DIRECT
Plant ANatomical entity (PAN)	collective leaf structure	0	0.46	Least Informative	DIRECT
Plant ANatomical entity (PAN)	stalk	0	0.6176	Least Informative	DIRECT
Plant ANatomical entity (PAN)	branch	0	0.5373	Least Informative	DIRECT
Plant ANatomical entity (PAN)	phyllome apex	0	0.5956	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	whole plant development stage	0	0.1547	--	DIRECT
Plant structure DEvelopment stage (PDE)	1 main shoot growth stage	0	0.3245	--	DIRECT
Plant structure DEvelopment stage (PDE)	sporophyte vegetative stage	0	0.1593	--	DIRECT
Plant structure DEvelopment stage (PDE)	floral organ differentiation stage	0	0.07163	--	DIRECT
Plant structure DEvelopment stage (PDE)	corolla development stage	0	0.1484	--	DIRECT
Plant structure DEvelopment stage (PDE)	flowering stage	0	0.1648	--	DIRECT
Plant structure DEvelopment stage (PDE)	plant embryo stage	0	0.2319	--	DIRECT
Plant structure DEvelopment stage (PDE)	collective plant organ structure development stage	0	0.0282	--	DIRECT
Plant structure DEvelopment stage (PDE)	plant organ development stage	0	0.06127	--	DIRECT
Plant structure DEvelopment stage (PDE)	reproductive shoot system development stage	0	0.0371	--	DIRECT
Plant structure DEvelopment stage (PDE)	collective phyllome structure development stage	0	0.07163	--	DIRECT
Plant structure DEvelopment stage (PDE)	phyllome development stage	0	0.3879	--	DIRECT
Plant structure DEvelopment stage (PDE)	floral organ formation stage	0	0.07163	--	DIRECT
Plant structure DEvelopment stage (PDE)	leaf development stage	1	0.3879	--	INHERITED FROM: 4 leaf senescence stage
Plant structure DEvelopment stage (PDE)	leaf production stage	1	0.3272	--	INHERITED FROM: LP.02 two leaves visible stage || LP.10 ten leaves visible stage || LP.04 four leaves visible stage || LP.08 eight leaves visible stage || LP.12 twelve leaves visible stage || LP.06 six leaves visible stage
Plant structure DEvelopment stage (PDE)	flower development stage	1	0.05402	--	INHERITED FROM: corolla development stage || flowering stage || floral organ differentiation stage || floral organ formation stage
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	0.1584	--	INHERITED FROM: sporophyte vegetative stage || C globular stage || LP.10 ten leaves visible stage || E expanded cotyledon stage || LP.12 twelve leaves visible stage || F mature embryo stage || LP.04 four leaves visible stage || D bilateral stage || LP.06 six leaves visible stage || LP.08 eight leaves visible stage || LP.02 two leaves visible stage || plant embryo stage || 1 main shoot growth stage
Plant structure DEvelopment stage (PDE)	shoot system development stage	1	0.02956	--	INHERITED FROM: phyllome development stage || reproductive shoot system development stage || floral organ formation stage || floral organ differentiation stage || flowering stage || corolla development stage || plant organ development stage || 4 leaf senescence stage
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	0.1584	--	INHERITED FROM: LP.08 eight leaves visible stage || LP.12 twelve leaves visible stage || E expanded cotyledon stage || LP.10 ten leaves visible stage || LP.06 six leaves visible stage || sporophyte vegetative stage || C globular stage || 1 main shoot growth stage || D bilateral stage || F mature embryo stage || LP.04 four leaves visible stage || plant embryo stage || LP.02 two leaves visible stage
Plant structure DEvelopment stage (PDE)	4 leaf senescence stage	0	0.3895	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	E expanded cotyledon stage	0	0.2861	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	F mature embryo stage	0	0.3205	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	C globular stage	0	0.3087	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	D bilateral stage	0	0.301	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.12 twelve leaves visible stage	0	0.479	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.08 eight leaves visible stage	0	0.4752	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.02 two leaves visible stage	0	0.4603	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.10 ten leaves visible stage	0	0.4234	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.04 four leaves visible stage	0	0.3479	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	LP.06 six leaves visible stage	0	0.4268	Least Informative	DIRECT

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Acting on the CH-OH group of donors	0	1.372	--	DIRECT
Enzyme Commission (EC)	3-hydroxyacyl-CoA dehydrogenase	0	2.753	--	DIRECT
Enzyme Commission (EC)	Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)	0	2.929	--	DIRECT
Enzyme Commission (EC)	Ketol-acid reductoisomerase (NADP(+))	0	2.929	--	DIRECT
Enzyme Commission (EC)	Glycerol-3-phosphate dehydrogenase (NAD(P)(+))	0	2.929	--	DIRECT
Enzyme Commission (EC)	With other, known, acceptors	0	2.753	--	DIRECT
Enzyme Commission (EC)	5,10-methenyltetrahydromethanopterin hydrogenase	0	2.929	--	DIRECT
Enzyme Commission (EC)	Prephenate dehydrogenase	0	2.929	--	DIRECT
Enzyme Commission (EC)	Pyrroline-5-carboxylate reductase	0	2.929	--	DIRECT
Enzyme Commission (EC)	Carbon-oxygen lyases	0	1.208	--	DIRECT
Enzyme Commission (EC)	Enoyl-CoA hydratase	0	2.753	--	DIRECT
Enzyme Commission (EC)	Acting on hydroxy acids and derivatives	0	2.753	--	DIRECT
Enzyme Commission (EC)	3-hydroxybutyryl-CoA epimerase	0	2.753	--	DIRECT
Enzyme Commission (EC)	Delta(3)-Delta(2)-enoyl-CoA isomerase	0	2.628	--	DIRECT
Enzyme Commission (EC)	UDP-glucose 6-dehydrogenase	0.00000000000003045	2.753	--	DIRECT
Enzyme Commission (EC)	Glycerol-3-phosphate dehydrogenase (NAD(+))	0.000000000000156	2.929	--	DIRECT
Enzyme Commission (EC)	Ferric-chelate reductase (NADPH)	0.00000003473	3.23	--	DIRECT
Enzyme Commission (EC)	Carnitine 3-dehydrogenase	0.0000005841	2.753	--	DIRECT
Enzyme Commission (EC)	8-hydroxy-5-deazaflavin:NADPH oxidoreductase	0.000004631	3.23	--	DIRECT
Enzyme Commission (EC)	Tagaturonate reductase	0.000004982	2.929	--	DIRECT
Enzyme Commission (EC)	3-hydroxyisobutyrate dehydrogenase	0.000009763	2.929	--	DIRECT
Enzyme Commission (EC)	Mannitol 2-dehydrogenase	0.00001696	2.929	--	DIRECT
Enzyme Commission (EC)	Chorismate mutase	0.00002268	2.385	--	DIRECT
Enzyme Commission (EC)	UDP-N-acetyl-D-mannosamine dehydrogenase	0.00003338	2.753	--	DIRECT
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0.00006617	2.452	--	DIRECT
Enzyme Commission (EC)	D-octopine dehydrogenase	0.0001056	2.929	--	DIRECT
Enzyme Commission (EC)	3-hydroxybutyryl-CoA dehydrogenase	0.0005117	2.929	--	DIRECT
Enzyme Commission (EC)	Acting on hydrogen as donors	0.00484	2.452	--	INHERITED FROM: With other, known, acceptors || 5,10-methenyltetrahydromethanopterin hydrogenase
Enzyme Commission (EC)	Oxidizing metal ions	1	2.275	--	INHERITED FROM: Ferric-chelate reductase (NADPH) || With NAD(+) or NADP(+) as acceptor
Enzyme Commission (EC)	Oxidoreductases	0	0.7328	Least Informative	DIRECT
Enzyme Commission (EC)	Isomerases	0.000000000001131	1.026	Moderately Informative	DIRECT
Enzyme Commission (EC)	Lyases	0.4267	0.8775	Moderately Informative	INHERITED FROM: Enoyl-CoA hydratase || Carbon-oxygen lyases || Hydro-lyases
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	1.437	Informative	DIRECT
Enzyme Commission (EC)	Hydro-lyases	0	1.385	Informative	DIRECT
Enzyme Commission (EC)	Racemases and epimerases	0	1.711	Informative	DIRECT
Enzyme Commission (EC)	Intramolecular oxidoreductases	0.000000000004343	1.505	Informative	DIRECT
Enzyme Commission (EC)	Acting on the CH-CH group of donors	1	1.586	Informative	INHERITED FROM: Prephenate dehydrogenase
Enzyme Commission (EC)	Acting on the CH-NH group of donors	1	1.686	Informative	INHERITED FROM: Pyrroline-5-carboxylate reductase || 8-hydroxy-5-deazaflavin:NADPH oxidoreductase || With NAD(+) or NADP(+) as acceptor || D-octopine dehydrogenase
Enzyme Commission (EC)	Intramolecular transferases	1	1.606	Informative	INHERITED FROM: Chorismate mutase
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	1.907	Highly Informative	DIRECT
Enzyme Commission (EC)	Transposing C=C bonds	0	2.116	Highly Informative	DIRECT
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0.0052	1.783	Highly Informative	INHERITED FROM: Prephenate dehydrogenase
Enzyme Commission (EC)	Transferring other groups	1	1.849	Highly Informative	INHERITED FROM: Chorismate mutase

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