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Home > SCOP hierarchy > Dihydrofolate reductases family

Dihydrofolate reductases family

SCOP classification

Root:	SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:	Alpha and beta proteins (a/b) [ 51349] (147)
Fold:	Dihydrofolate reductase-like [ 53596]
Superfamily:	Dihydrofolate reductase-like [ 53597] (2)
Family:	Dihydrofolate reductases [ 53598] (3)

Family statistics

	Genomes (1,662)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	1,854	14,451	29
Proteins	1,854	14,450	29

Enzyme Commission (EC)

(show details)

	EC term	FDR (all)	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	Oxidoreductases	0	Least Informative	Direct
Enzyme Commission (EC)	Transferring one-carbon groups	0.000000268	Least Informative	Direct
Enzyme Commission (EC)	Methyltransferases	0.0000000002691	Moderately Informative	Direct
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	Informative	Direct

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)

	EC term	FDR (all)	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Oxidoreductases	0	Least Informative	Direct
Enzyme Commission (EC)	Transferases	1	Least Informative	Inherited
Enzyme Commission (EC)	Transferring one-carbon groups	0.000008944	Moderately Informative	Direct
Enzyme Commission (EC)	Acting on the CH-NH group of donors	0	Informative	Direct
Enzyme Commission (EC)	Methyltransferases	0.00000001167	Informative	Direct
Enzyme Commission (EC)	With NAD(+) or NADP(+) as acceptor	0	Highly Informative	Direct

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links


Superfamily level	Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Superfamily level	Family level

Alignments of sequences to 36 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Dihydrofolate reductase-like domain.


Superfamily level	Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]