L30e/L7ae ribosomal proteins family

SCOP classification

• Root: SCOP hierarchy in SUPERFAMILY [ 0] (11)
• Class: Alpha and beta proteins (a+b) [ 53931] (376)
• Fold: Bacillus chorismate mutase-like [ 55297] (9)
• Superfamily: L30e-like [ 55315] (3)
• Family: L30e/L7ae ribosomal proteins [ 55316] (4)

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Family statistics

	Genomes (659)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	1,392	4,116	23
Proteins	1,392	4,113	23

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Disease Ontology (DO)

Highlighted in gray are those with FDR_all>0.001

	DO term	FDR (all)	IC level	SDDO level	Annotation (direct or inherited)
Disease Ontology (DO)	disease of cellular proliferation	0	0.2322	--	DIRECT
Disease Ontology (DO)	cancer	0	0.2555	--	DIRECT

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Worm Phenotype (WP)

Highlighted in gray are those with FDR_all>0.001

	WP term	FDR (all)	IC level	SDWP level	Annotation (direct or inherited)
Worm Phenotype (WP)	growth variant	0	0.3438	--	DIRECT
Worm Phenotype (WP)	postembryonic development variant	0	0.269	--	DIRECT
Worm Phenotype (WP)	embryonic lethal	0	0.046	--	DIRECT
Worm Phenotype (WP)	lethal	0	0.00521	--	DIRECT
Worm Phenotype (WP)	fertility variant	0	0.05937	--	DIRECT
Worm Phenotype (WP)	transgene expression variant	0	0.773	--	DIRECT
Worm Phenotype (WP)	development variant	0	0.001482	--	DIRECT
Worm Phenotype (WP)	morphology variant	0	0.046	--	DIRECT
Worm Phenotype (WP)	organism development variant	0	0.00297	--	DIRECT
Worm Phenotype (WP)	organ system physiology variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	organism physiology variant	0	0.1342	--	DIRECT
Worm Phenotype (WP)	organism homeostasis metabolism variant	0	0.1444	--	DIRECT
Worm Phenotype (WP)	reproductive system physiology variant	0	0.05515	--	DIRECT
Worm Phenotype (WP)	maternal sterile	0	0.1213	--	DIRECT
Worm Phenotype (WP)	hermaphrodite sterile	0	0.1203	--	DIRECT
Worm Phenotype (WP)	gene expression variant	0	0.6256	--	DIRECT
Worm Phenotype (WP)	embryonic development variant	0	0.04518	--	DIRECT
Worm Phenotype (WP)	hermaphrodite fertility variant	0	0.0947	--	DIRECT
Worm Phenotype (WP)	hermaphrodite fertility reduced	0	0.1193	--	DIRECT
Worm Phenotype (WP)	fertility reduced	0	0.06449	--	DIRECT
Worm Phenotype (WP)	pachytene region organization variant	0.000004604	1.727	--	DIRECT
Worm Phenotype (WP)	meiotic progression prophase variant	0.00002594	1.407	--	DIRECT
Worm Phenotype (WP)	meiotic progression during oogenesis variant	0.00004701	1.321	--	DIRECT
Worm Phenotype (WP)	germ cell compartment morphology variant	0.00006205	1.354	--	DIRECT
Worm Phenotype (WP)	oogenesis variant	0.0001188	1.237	--	DIRECT
Worm Phenotype (WP)	meiosis variant	0.0002611	1.263	--	DIRECT
Worm Phenotype (WP)	gonad morphology variant	0.0003	1.306	--	DIRECT
Worm Phenotype (WP)	feeding behavior variant	0.0003067	1.25	--	DIRECT
Worm Phenotype (WP)	germ cell morphology variant	0.001033	1.156	--	INHERITED FROM: oocyte morphology variant || germ cell compartment morphology variant || oocyte number decreased || germ cell compartment expansion variant
Worm Phenotype (WP)	response to bacteria variant	0.001557	1.426	--	INHERITED FROM: avoids bacterial lawn
Worm Phenotype (WP)	organ system morphology variant	0.0216	0.7516	--	INHERITED FROM: rachis morphology variant || diplotene region organization variant || gonad vesiculated || gonad morphology variant || rachis narrow || pachytene region organization variant
Worm Phenotype (WP)	cell morphology variant	0.02291	0.7558	--	INHERITED FROM: germ cell compartment morphology variant || oocyte number decreased || oocyte morphology variant || germ cell compartment expansion variant
Worm Phenotype (WP)	behavior variant	0.06264	0.6859	--	INHERITED FROM: avoids bacterial lawn || feeding behavior variant
Worm Phenotype (WP)	gametogenesis variant	0.1039	1.013	--	INHERITED FROM: germ cell differentiation variant || pachytene progression during oogenesis variant || meiotic progression prophase variant || oogenesis variant || pachytene region organization variant || meiotic progression during oogenesis variant || meiosis variant || diplotene progression during oogenesis variant || diplotene region organization variant || oocyte number decreased
Worm Phenotype (WP)	physiology variant	1	0	--	INHERITED FROM: hermaphrodite fertility variant || meiotic progression during oogenesis variant || organism metabolism processing variant || reproductive system physiology variant || transgene expression variant || diplotene progression during oogenesis variant || gene expression variant || early embryonic lethal || extended life span || oogenesis variant || organism homeostasis metabolism variant || oocyte number decreased || avoids bacterial lawn || lethal || diplotene region organization variant || organism physiology variant || meiosis variant || germ cell differentiation variant || development variant || cell physiology variant || hermaphrodite sterile || growth variant || hermaphrodite fertility reduced || sick || embryonic development variant || embryonic lethal || fertility variant || pattern of transgene expression variant || feeding behavior variant || pachytene progression during oogenesis variant || meiotic progression prophase variant || postembryonic development variant || organ system physiology variant || maternal sterile || organism development variant || fertility reduced || pachytene region organization variant
Worm Phenotype (WP)	sterile	1	0.1135	--	INHERITED FROM: hermaphrodite sterile || maternal sterile
Worm Phenotype (WP)	organism metabolism processing variant	0	0.4899	Least Informative	DIRECT
Worm Phenotype (WP)	cell physiology variant	0	0.5955	Least Informative	DIRECT
Worm Phenotype (WP)	cell development variant	0.001895	0.6752	Least Informative	INHERITED FROM: germ cell differentiation variant || meiotic progression during oogenesis variant || diplotene progression during oogenesis variant || meiosis variant || diplotene region organization variant || oocyte number decreased || pachytene progression during oogenesis variant || meiotic progression prophase variant || oogenesis variant || pachytene region organization variant
Worm Phenotype (WP)	organism environmental stimulus response variant	0.006782	0.6614	Least Informative	INHERITED FROM: avoids bacterial lawn
Worm Phenotype (WP)	organism behavior variant	0.06178	0.6859	Least Informative	INHERITED FROM: avoids bacterial lawn || feeding behavior variant
Worm Phenotype (WP)	pattern of transgene expression variant	0	0.9833	Moderately Informative	DIRECT
Worm Phenotype (WP)	germ cell differentiation variant	0.0004101	1.167	Moderately Informative	DIRECT
Worm Phenotype (WP)	early embryonic lethal	0.0005995	1.178	Moderately Informative	DIRECT
Worm Phenotype (WP)	germ cell development variant	0.002072	1.013	Moderately Informative	INHERITED FROM: meiotic progression during oogenesis variant || pachytene region organization variant || diplotene region organization variant || oocyte number decreased || meiosis variant || diplotene progression during oogenesis variant || oogenesis variant || pachytene progression during oogenesis variant || meiotic progression prophase variant
Worm Phenotype (WP)	reproductive system morphology variant	0.003327	1.078	Moderately Informative	INHERITED FROM: rachis narrow || diplotene region organization variant || pachytene region organization variant || gonad vesiculated || rachis morphology variant || gonad morphology variant
Worm Phenotype (WP)	cell type morphology variant	0.008074	0.8878	Moderately Informative	INHERITED FROM: oocyte morphology variant || germ cell compartment morphology variant || germ cell compartment expansion variant || oocyte number decreased
Worm Phenotype (WP)	cell cycle variant	0.03647	1.225	Moderately Informative	INHERITED FROM: diplotene region organization variant || diplotene progression during oogenesis variant || meiosis variant || pachytene region organization variant || meiotic progression prophase variant || pachytene progression during oogenesis variant
Worm Phenotype (WP)	cell division variant	0.122	1.036	Moderately Informative	INHERITED FROM: meiotic progression prophase variant || pachytene progression during oogenesis variant || pachytene region organization variant || meiosis variant || diplotene progression during oogenesis variant || diplotene region organization variant
Worm Phenotype (WP)	pachytene progression during oogenesis variant	0.000007712	1.565	Informative	DIRECT
Worm Phenotype (WP)	diplotene progression during oogenesis variant	0.000007712	1.655	Informative	DIRECT
Worm Phenotype (WP)	germ cell compartment expansion variant	0.00002671	1.468	Informative	DIRECT
Worm Phenotype (WP)	rachis morphology variant	0.00002829	1.623	Informative	DIRECT
Worm Phenotype (WP)	avoids bacterial lawn	0.00003983	1.49	Informative	DIRECT
Worm Phenotype (WP)	oocyte morphology variant	0.000132	1.292	Informative	DIRECT
Worm Phenotype (WP)	sick	0.0002568	1.727	Informative	DIRECT
Worm Phenotype (WP)	life span variant	0.01254	1.321	Informative	INHERITED FROM: extended life span
Worm Phenotype (WP)	diplotene region organization variant	0.000001382	1.99	Highly Informative	DIRECT
Worm Phenotype (WP)	gonad vesiculated	0.000002217	2.167	Highly Informative	DIRECT
Worm Phenotype (WP)	rachis narrow	0.000005754	1.866	Highly Informative	DIRECT
Worm Phenotype (WP)	oocyte number decreased	0.00000756	1.924	Highly Informative	DIRECT
Worm Phenotype (WP)	extended life span	0.0002063	1.814	Highly Informative	DIRECT

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Yeast Phenotype (YP)

Highlighted in gray are those with FDR_all>0.001

	YP term	FDR (all)	IC level	SDYP level	Annotation (direct or inherited)
Yeast Phenotype (YP)	cellular processes	0	0.09186	--	DIRECT
Yeast Phenotype (YP)	stress resistance	0	0.1452	--	DIRECT

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Fly Phenotype (FP)

Highlighted in gray are those with FDR_all>0.001

	FP term	FDR (all)	IC level	SDFP level	Annotation (direct or inherited)
Fly Phenotype (FP)	phenotype	0	0.06546	--	DIRECT

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Xenopus Anatomy (XA)

Highlighted in gray are those with FDR_all>0.001

	XA term	FDR (all)	IC level	SDXA level	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	head region	0	0.4759	--	DIRECT
Xenopus ANatomical entity (XAN)	trunk region	0	0.388	--	DIRECT
Xenopus ANatomical entity (XAN)	genital system	0	0.5751	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical structure	0	0	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical group	0	0.1408	--	DIRECT
Xenopus ANatomical entity (XAN)	organism subdivision	0	0.1679	--	DIRECT
Xenopus ANatomical entity (XAN)	compound organ	0	0.2177	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical region	0	0.1803	--	DIRECT
Xenopus ANatomical entity (XAN)	multicellular anatomical structure	0	0.1131	--	DIRECT
Xenopus ANatomical entity (XAN)	anatomical system	1	0.283	--	INHERITED FROM: urogenital system || genital system
Xenopus ANatomical entity (XAN)	whole organism	1	0.0884	--	INHERITED FROM: urogenital system || head region || genital system || anatomical group || cavitated compound organ || multicellular anatomical structure || compound organ || trunk || anatomical region || trunk region || organism subdivision || head
Xenopus ANatomical entity (XAN)	urogenital system	0	0.4777	Least Informative	DIRECT
Xenopus ANatomical entity (XAN)	head	0	0.4777	Least Informative	DIRECT
Xenopus ANatomical entity (XAN)	trunk	0	0.3894	Least Informative	DIRECT
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	0.2685	Least Informative	DIRECT
Xenopus DEvelopment stage (XDE)	NF stage	0	0.01895	--	DIRECT

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Arabidopsis Plant Ontology (AP)

Highlighted in gray are those with FDR_all>0.001

	AP term	FDR (all)	IC level	SDAP level	Annotation (direct or inherited)
Plant ANatomical entity (PAN)	shoot system	0	0.05272	--	DIRECT
Plant ANatomical entity (PAN)	plant organ	0	0.2391	--	DIRECT
Plant ANatomical entity (PAN)	stem internode	0	0.5373	--	DIRECT
Plant ANatomical entity (PAN)	cardinal organ part	0	0.4385	--	DIRECT
Plant ANatomical entity (PAN)	plant axis	0	0.3257	--	DIRECT
Plant ANatomical entity (PAN)	root system	0	0.4584	--	DIRECT
Plant ANatomical entity (PAN)	shoot axis	0	0.3985	--	DIRECT
Plant ANatomical entity (PAN)	multi-tissue plant structure	0	0.2335	--	DIRECT
Plant ANatomical entity (PAN)	collective plant structure	0	0.01555	--	DIRECT
Plant ANatomical entity (PAN)	cardinal part of multi-tissue plant structure	0	0.437	--	DIRECT
Plant ANatomical entity (PAN)	plant structure	1	0	--	INHERITED FROM: root || collective plant structure || shoot internode || cardinal organ part || multi-tissue plant structure || shoot apex || stem internode || shoot system || plant organ || stem || root system || cardinal part of multi-tissue plant structure || plant axis || seed || shoot axis
Plant ANatomical entity (PAN)	collective plant organ structure	1	0.03998	--	INHERITED FROM: root system || root || stem || shoot internode || shoot apex || stem internode || shoot axis || shoot system
Plant ANatomical entity (PAN)	shoot apex	0	0.481	Least Informative	DIRECT
Plant ANatomical entity (PAN)	shoot internode	0	0.5373	Least Informative	DIRECT
Plant ANatomical entity (PAN)	root	0	0.4679	Least Informative	DIRECT
Plant ANatomical entity (PAN)	seed	0	0.5189	Least Informative	DIRECT
Plant ANatomical entity (PAN)	stem	0	0.4777	Least Informative	DIRECT
Plant structure DEvelopment stage (PDE)	whole plant development stage	0	0.1547	--	DIRECT
Plant structure DEvelopment stage (PDE)	sporophyte vegetative stage	0	0.1593	--	DIRECT
Plant structure DEvelopment stage (PDE)	plant embryo stage	0	0.2319	--	DIRECT
Plant structure DEvelopment stage (PDE)	life of whole plant stage	1	0.1584	--	INHERITED FROM: sporophyte vegetative stage || F mature embryo stage || plant embryo stage
Plant structure DEvelopment stage (PDE)	sporophyte development stage	1	0.1584	--	INHERITED FROM: sporophyte vegetative stage || F mature embryo stage || plant embryo stage
Plant structure DEvelopment stage (PDE)	F mature embryo stage	0	0.3205	Least Informative	DIRECT

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Enzyme Commission (EC)

Highlighted in gray are those with FDR_all>0.001

	EC term	FDR (all)	IC level	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Endoribonucleases producing 5'-phosphomonoesters	0	1.767	--	DIRECT
Enzyme Commission (EC)	Ribonuclease P	0	2.531	--	DIRECT
Enzyme Commission (EC)	Hydrolases	0	0.4043	Least Informative	DIRECT
Enzyme Commission (EC)	Acting on ester bonds	0	0.8756	Moderately Informative	DIRECT

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