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Home > SCOP hierarchy > SRCR-like superfamily

SRCR-like superfamily

SCOP classification

Root:	SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:	Alpha and beta proteins (a+b) [ 53931] (376)
Fold:	SRCR-like [ 56486] (2)
Superfamily:	SRCR-like [ 56487] (2)
Families:	Scavenger receptor cysteine-rich (SRCR) domain [ 56488]
	Hepsin, N-terminal domain [ 103355]

Superfamily statistics

	Genomes (173)	Uniprot 2018_03 genome	PDB chains (SCOP 1.75)
Domains	11,962	23,812	3
Proteins	4,041	8,875	3

Functional annotation

General category	Regulation
Detailed category	Receptor activity

Document: Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)

	EC term	FDR (all)	SDEO level	Annotation (direct or inherited)
Enzyme Commission (EC)	Acting on peptide bonds (peptide hydrolases)	0	Least Informative	Direct
Enzyme Commission (EC)	Serine endopeptidases	0	Moderately Informative	Direct

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)

	DO term	FDR (all)	SDDO level	Annotation (direct or inherited)
Disease Ontology (DO)	disease by infectious agent	0.1327	Moderately Informative	Inherited
Disease Ontology (DO)	viral infectious disease	0.1306	Informative	Inherited

Document: DO annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)

	XA term	FDR (all)	SDXA level	Annotation (direct or inherited)
Xenopus ANatomical entity (XAN)	cavitated compound organ	0	Least Informative	Direct
Xenopus DEvelopment stage (XDE)	embryonic stage	0.1364	Moderately Informative	Inherited
Xenopus DEvelopment stage (XDE)	early tailbud stage	0.006761	Highly Informative	Inherited

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)

	EC term	FDR (all)	SDEC level	Annotation (direct or inherited)
Enzyme Commission (EC)	Oxidoreductases	0.0000002305	Least Informative	Direct
Enzyme Commission (EC)	Hydrolases	0.0008644	Least Informative	Direct
Enzyme Commission (EC)	Acting on peptide bonds (peptidases)	0.0000000000009368	Moderately Informative	Direct
Enzyme Commission (EC)	Acting on the CH-NH(2) group of donors	0	Informative	Direct
Enzyme Commission (EC)	Serine endopeptidases	0	Informative	Direct
Enzyme Commission (EC)	With oxygen as acceptor	0	Highly Informative	Direct

Document: EC annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 4 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a SRCR-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 4 hidden Markov models representing the SRCR-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Disease Ontology (DO) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]