SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.


Zn-binding ribosomal proteins superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Rubredoxin-like [ 57769] (17)
Superfamily:   Zn-binding ribosomal proteins [ 57829] (8)
Families:   Ribosomal protein L37ae [ 57830]
  Ribosomal protein L37e [ 57833]
  Ribosomal protein L44e [ 57836]
  Ribosomal protein S27e [ 90217]
  Ribosomal protein L32p [ 144200]
  Ribosomal protein L33p [ 144203]
  Ribosomal protein L40e [ 161181]
  Ribosomal protein S27a [ 161184]


Superfamily statistics
Genomes (3,219) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 12,314 70,788 32
Proteins 12,304 70,752 32


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Disease Ontology (DO)

(show details) Document: DO annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)general pace of development variant0Least InformativeDirect
Worm Phenotype (WP)retarded heterochronic variations0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)larval growth variant0Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.003715Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.004433Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.005863Least InformativeInherited
Worm Phenotype (WP)organ system morphology variant0.008943Least InformativeInherited
Worm Phenotype (WP)cell morphology variant0.009762Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.04594Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.00000003406Moderately InformativeDirect
Worm Phenotype (WP)feeding behavior variant0.0000009021Moderately InformativeDirect
Worm Phenotype (WP)level of transgene expression variant0.0001928Moderately InformativeDirect
Worm Phenotype (WP)germ cell morphology variant0.0002408Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.0007344Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.000747Moderately InformativeDirect
Worm Phenotype (WP)metabolic pathway variant0.0008494Moderately InformativeDirect
Worm Phenotype (WP)reproductive system morphology variant0.0009944Moderately InformativeDirect
Worm Phenotype (WP)cell homeostasis metabolism variant0.04204Moderately InformativeInherited
Worm Phenotype (WP)pleiotropic defects severe early emb0.00000000000003527InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.00000004594InformativeDirect
Worm Phenotype (WP)germ cell cytoplasmic morphology variant0.001478InformativeInherited
Worm Phenotype (WP)RNA expression variant0.00382InformativeInherited
Worm Phenotype (WP)RNA processing variant0.000003032Highly InformativeDirect
Worm Phenotype (WP)cytoplasmic processing body variant0.00001725Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0Least InformativeDirect

Document: FP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0.5773Least InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)germ cell0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)sensory system0.001676Moderately InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.009868Moderately InformativeInherited
Xenopus ANatomical entity (XAN)viscus0.3012Moderately InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system0.373Moderately InformativeInherited
Xenopus ANatomical entity (XAN)endomesoderm0InformativeDirect
Xenopus ANatomical entity (XAN)skeletal system0.0004373InformativeDirect
Xenopus ANatomical entity (XAN)connective tissue0.0007659InformativeDirect
Xenopus ANatomical entity (XAN)eye0.0009686InformativeDirect
Xenopus ANatomical entity (XAN)muscle0.002233InformativeInherited
Xenopus ANatomical entity (XAN)solid compound organ0.0106InformativeInherited
Xenopus ANatomical entity (XAN)pancreas0.00003372Highly InformativeDirect
Xenopus ANatomical entity (XAN)bone tissue0.00008545Highly InformativeDirect
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect
Xenopus DEvelopment stage (XDE)climax stage0Moderately InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect

Document: AP annotation of SCOP domains

InterPro annotation
Cross references IPR011332 SSF57829 Protein matches
Abstract

This entry represents a rubredoxin-like metal-binding fold found in ribosomal proteins L37ae, L37e, L44e and S27e. This domain contains two CX(n)C motifs (where n is usually two) [PubMed15184028, PubMed15096641].


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Disease Ontology (DO) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 14 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Zn-binding ribosomal proteins domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 14 hidden Markov models representing the Zn-binding ribosomal proteins superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Disease Ontology (DO) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]